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| 1 | Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress显示文摘癌症房间以他们的能力著名给新陈代谢的小径换新电线在各种各样的压力条件下面支持幸存和增长。尽管在肝生产了,酉同类身体没在正常的成年的肝房间被消费。我们这里发现酉同类分解代谢或 ketolysis 在 hepatocellular 被重新激活在营养剥夺条件下面的癌(HCC ) 房间。机械学地, 3-oxoacid CoA-transferase 1 (OXCT1 ) ,其表情在正常的成年的肝纸巾被压制的限制率的 ketolytic 酶,被浆液重新导致被触发饥饿的 mTORC2-AKT-SP1 在 HCC 房间发信号。而且,我们观察到在 HCC 的那提高的 ketolysis 为 AMPK 激活的压抑是批评的并且保护 HCC 房间免受过多的 autophagy 的伤害,从而提高肿瘤生长。重要地,临床的 HCC 样品的分析表明那增加的 OXCT1 表情预言更高耐心的死亡。一起拿,我们这里揭开剥夺营养的 HCC 房间为精力由采用酉同类身体的新奇新陈代谢的改编供应和癌症前进。 | De Huang Tingting Li Lin Wang Long Zhang Ronghui Yan Kui Li Songge Xing Gongwei Wu Lan Hu Weidong Jia Sheng-Cai Lin Chi V Dang Libing Song Ping Gao Huafeng Zhang | 2016 | Cell Research2016,26,10: | 27 |
| 2 | The prognostic value of preoperative serum levels of CEA,CA19-9 and CA72-4 in patients with colorectal cancer显示文摘INTRODUCTIONCarcinoembryonic antigen ( CEA) , originally described by Gold and Freedman [1] in 1965, is now an acknowledged member of immunoglobulin superfamily[2],with a role as an intracellular adhesion molecule[3].Carbohydrate antigen 19-9(CA19-9), obtained with a monoclonal antibody produced by immunizing a monoclonal antibody produced by immunizing a mouse with a colonic cancer cell line in 1979[4],is a ligand for E-selectin that plays an important role in the addhesion of cancer cells to endothelial cells [5,6]. | Chao Xu Zheng~1 Wen Hua Zhan~1 Ji Zong Zhao~2 Dong Zheng~3 Dong Ping Wang~1 Yu Long He~1 Zhang Qing Zheng~1 ~1Department of General Surgery,~2Laboratory of Surgery,~3Department of Medicine,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,Guangzhou 510080,Guangdong Province,ChinaDr.Chao Xu Zheng now working as a surgeon and lecturer in the Department of General Surgery,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,who is a Ph.D.student,having 7 papers published. | 2001 | World Journal of Gastroenterology2001,7,3: | 25 |
| 3 | Mechanical Properties Prediction of the Mechanical Clinching Joints Based on Genetic Algorithm and BP Neural Network显示文摘For optimal design of mechanical clinching steel-aluminum joints, the back propagation(BP) neural network is used to research the mapping relationship between joining technique parameters including sheet thickness, sheet hardness, joint bottom diameter etc., and mechanical properties of shearing and peeling in order to investigate joining technology between various material plates in the steel-aluminum hybrid structure car body.Genetic algorithm(GA) is adopted to optimize the back-propagation neural network connection weights.The training and validating samples are made by the BTM? Tog-L-Loc system with different technologic parameters.The training samples' parameters and the corresponding joints' mechanical properties are supplied to the artificial neural network(ANN) for training.The validating samples' experimental data is used for checking up the prediction outputs.The calculation results show that GA can improve the model's prediction precision and generalization ability of BP neural network.The comparative analysis between the experimental data and the prediction outputs shows that ANN prediction models after training can effectively predict the mechanical properties of mechanical clinching joints and prove the feasibility and reliability of the intelligent neural networks system when used in the mechanical properties prediction of mechanical clinching joints.The prediction results can be used for a reference in the design of mechanical clinching steel-aluminum joints. | LONG Jiangqi LAN Fengchong CHEN Jiqing YU Ping | 2009 | Chinese Journal of Mechanical Engineering2009,22,1: | 22 |
| 4 | Relationship between expression of α-fetoprotein messenger RNA and some clinical parameters of human hepatocelular carcinoma显示文摘METHODWedetectedtheexpressionofAFPinmRNAlevelintissuesamplesfrom52patientssuferingfromHCCbyRTPCRmethod.RESULTSThepositiverat... | HE Ping, TANG Zhao You, YE Sheng Long and LIU Bin Bin | 1999 | World Journal of Gastroenterology1999,5,2: | 23 |
| 5 | Effectiveness of Different Waist Circumference Cut-off Values in Predicting Metabolic Syndrome Prevalence and Risk Factors in Adults in China显示文摘Objective To study the effectiveness of waist circumference cut-off values in predicting the prevalence of metabolic syndrome(MetS) and risk factors in adults in China. Methods A cross-sectional survey was condcuted in 14 provinces(autonomous region, municipality) in China. A total of 47 325 adults aged ≥20 years were selected by multistage stratified sampling, and questionnaire survey and physical and clinical examination were conducted among them. MetS was defined according to the International Diabetes Federation(IDF) criteria and modified IDF criteria.Results The age-standardized prevalence of MetS was 24.2%(22.1% in men and 25.8% in women) and 19.5%(22.1% in men and 18.0% in women) according to the IDF criteria and modified IDF criteria respectively. The age-standardized prevalence of pre-MetS was 8.1%(8.6% in men and 7.8% in women) according to the modified IDF criteria. The prevalence of MetS was higher in urban residents than rural residents and in northern China residents than in southern China residents. The prevalence of central obesity was about 30% in both men and women according to the ethnicity-specific cut-off values of waist circumference for central obesity(90 cm for men and 85 cm for women). Multivariate regression analysis revealed no significant difference in risk factors between the two MetS definitions. Conclusion Using both the modified IDF criteria and ethnicity-specific cut-off values of waist circumference can provide more useful information about the prevalence of MetS in China. | ZHOU Hai Cheng LAI Ya Xin SHAN Zhong Yan JIA Wei Ping YANG Wen Ying LU Ju Ming WENG Jian Ping JI Li Nong LIU Jie TIAN Hao Ming JI Qiu He ZHU Da Long CHEN Li GUO Xiao Hui ZHAO Zhi Gang Li Qiang ZHOU Zhi Guang GE Jia Pu SHAN Guang Liang | 2014 | Biomedical and Environmental Sciences2014,27,5: | 17 |
| 6 | Genetic diversity of Harpins from Xanthomonas oryzae and their activity to induce hypersensitive response and disease resistance in tobacco显示文摘Three hrfA (hypersensitive response-functioning faction A) homologues (hrf1, hrf2 and hrf3) are cloned from 12 strains of Xanthomonas oryzae using PCR based techniques. Hrf1, hrf2 and hrf3 are derived from strains belonging to X. o. pv. oryzae, X. o. pv. oryzicola and X. o. pv. oryzae respectively. Sequence analysis shows that all three genes encode glycine-rich pro-teins with various numbers of GGG-GG motifs. They all share a conserved cysteine residue at position 45 or 47. Hrf1 and hrf3 encode HarpinXoo while hrf2 encodes Harpinxooc. Hrf1 and hrf3 encodes two different types of HarpinXoo proteins. Hrf1 from X. o. pv. oryzae strains ( JxoIII, JxoIV, Jxov, Pxo61, Pxo76, Pxo79, Pxo99, Pxo99 and Pxo124) encodes a 15.6 kD HarpinXoo with 3 GGG-GG motifs while Hrf3 from strain Pxo86 and Pxo112 encodes a 15.9 kD Harpinxoo with 4 GGG-GG motifs. Harpinxooc encoded by hrf2 from X. o. pv. oryzicola (strain RS105) has the mo-lecular weight of 15.3 kD and contains 2 GGG-GG motifs. Cluster analysis is performed using deduced sequences of hrf1, hrf2 and hrf3 as well as previously reported Hpa1 and XopI protein sequence. The results indicated that Harpinxoo and Harpinxooc belong to two closely related sub-groups. Hrf, hrf2 and hrf3 are expressed in E. coli strain BL21 successfully. Under the same condition, hrf1, hrf2 and hrf3 are expressed at the level of 0.389, 0.530 and 0.083 mg/mL re-spectively. All expressed hrf1, hrf2 and hrf3 proteins (Harpins) are shown to be able to induce hypersensitive reaction and TMV resistance on tobacco. Among the three proteins, Hrf2 has the highest activity while Hrf3 has the lowest activity. | LI Ping, LU Xuzhong, SHAO Min, LONG Juying & WANG Jinsheng Department of Plant Pathology, Nanjing Agricultural University Key Laboratory of Monitoring and Management of Plant Disease and Pests, Ministry of Agriculture, Nanjing 210095, China | 2004 | Science China(Life Sciences)2004,47,5: | 15 |
| 7 | DNA storage:research landscape and future prospects显示文摘The global demand for data storage is currently outpacing the world’s storage capabilities.DNA,the carrier of natural genetic information,offers a stable,resource-and energy-efficient and sustainable data storage solution.In this review,we summarize the fundamental theory,research history,and technical challenges of DNA storage.From a quantitative perspective,we evaluate the prospect of DNA,and organic polymers in general,as a novel class of data storage medium. | Yiming Dong Fajia Sun Zhi Ping Qi Ouyang Long Qian | 2020 | National Science Review2020,7,6: | 12 |
| 8 | Seasonal and inter-annual variations in carbon fluxes and evapotranspiration over cotton field under drip irrigation with plastic mulch in an arid region of Northwest China显示文摘Xinjiang is the largest semi-arid and arid region in China, and drip irrigation under plastic mulch is widely used in this water-limited area. Quantifying carbon and water fluxes as well as investigating their environmental drivers over cotton fields is critical for understanding regional carbon and water budgets in Xinjiang, the largest cotton production basin of China. In this study, an eddy covariance(EC) technique was used to measure the carbon and water fluxes of cotton field under drip irrigation with plastic mulch in the growing seasons of 2009, 2010, 2012 and 2013 at Wulanwusu Agrometeorological Experiment Station, a representative oasis cropland in northern Xinjiang. The diurnal patterns of gross primary production(GPP), net ecosystem exchange(NEE) and evapotranspiration(ET) showed obviously sinusoidal variations from June to September, while the diurnal ecosystem respiration(Res) was stable between daytime and nighttime. The daytime hourly GPP and ET displayed asymptotic relationships with net solar radiation(Rnet), while showed concave patterns with raising vapor pressure deficit(VPD) and air temperature(Ta). The increases in hourly GPP and ET towards the maximum occurred over half ranges of VPD and Ta. The seasonal variations of GPP, NEE and ET were close to the cotton phenology, which almost reached the peak value in July. The cumulative GPP averaged 816.2±55.0 g C/m2 in the growing season(from April to October), and more than half of GPP was partitioned into NEE(mean value of –478.6±41.4 g C/m2). The mean seasonal ET was 501.3±13.9 mm, and the mean water use efficiency(WUE) was 1.0±0.1(mg C/g H2O)/d. The agro-ecosystem behaved as a carbon sink from squaring to harvest period, while it acted as a carbon source before the squaring time as well as after the harvest time. | Jie BAI Jin WANG Xi CHEN Ge Ping LUO Hao SHI Long Hui LI Jun Li LI | 2015 | Journal of Arid Land2015,7,2: | 12 |
| 9 | Internal solitons in the northern South China Sea from insitu observations显示文摘In this paper, we demonstrate the characteris- tics of strong internal solitons at the southern edge of Dong- sha Islands in the northern South China Sea (SCS) during May―June 1998, using in situ time series data from the con- ductivity temperature depth (CTD), acoustic Doppler current profiler (ADCP) and thermistor chain. Our measurements indicated that the strongest internal solitons were larger than 90 m in wave amplitude, and propagated approximately westward in traveling direction, with the maximum current speed of about 2 m/s and the period of 10―20 min. The strongest internal solitons occurred noticeably during May 14―16, 1998, which is consistent with the occurrence period of the diurnal-dominated spring internal tides. | FANG Wendong SHI Ping LONG Xiaomin MAO Qingwen | 2005 | Chinese Science Bulletin2005,50,15: | 10 |
| 10 | Effects of SLCO1 Bl and GATM gene variants on rosuvastatin-induced myopathy are unrelated to high plasma exposure of rosuvastatin and its metabolites显示文摘Myotoxicity is a sign ificant factor contributi ng to the poor adhere nee and reduced effective ness in the treatme nt of statins. Gen etic variations and high drug plasma exposure are considered as critique causes for statin-induced myopathy (SIM). This study aims to explore the sequential influences of rosuvastatin (RST) pharmacokinetic and myopathy-related single-nucleotide polymorphisms (SNPs) on the plasma exposure to RST and its metabolites: rosuvastatin lactone (RSTL) and /V-desmethyl rosuvastatin (DM-RST), and further on RST-induced myopathy. A total of 758 Chinese patients with coronary artery disease were enrolled and followed up SIM incidents for 2 years. The plasma concentrations of RST and its metabolites were determined through a validated ultra-performanee liquid chromatography mass spectrometry method. Nine SNPs in six genes were genotyped by using the Sequenom MassArray iPlex platform. Results revealed that ABCG2 rs2231142 variations were highly associated with the plasma concentrations of RST, RSTL, and DM-RST (Pad)<0.01, FDR < 0.05). CYP2C9 rs1057910 significantly affected the DM-RST concentration (Padj <0.01, FDR < 0.05). SLCO1B1 rs4149056 variant allele was significantly associated with high SIM risk (OR: 1.741, 95% Cl: 1.180-2.568, P = 0.0052, FDR = 0.0468). Glycine amidinotransferase (GATM) rs9806699 was marginally associated with SIM incidents (OR: 0.617, 95% Cl: 0.406-0.939, P = 0.0240, FDR = 0.0960). The plasma concentrations of RST and its metabolites were not significantly different between the SIM (n = 51) and control groups (n=707)(all P > 0.05). In conclusion, SLCO1B1 and GATM genetic variants are potential biomarkers for predicting RST-induced myopathy, and their effects on SIM are unrelated to the high plasma exposure of RST and its metabolites. | Xue Bai Bin Zhang Ping Wang Guan-lei Wang Jia-li Li Ding-sheng Wen Xing-zhen Long Hong-shuo Sun Yi-bin Liu Min Huang Shi-Iong Zhong | 2019 | Acta Pharmacologica Sinica2019,40,4: | 9 |
| 11 | Test for the effects of three surfactants on the penetration ability of the calcium chloride and water glass Solutions in dust显示文摘1IntroductionCalciumchlorideisoftenusedinthefieldofsoilstabilizationandraisingdustcontrolbecauseitcanreactwithwaterglas(Wu,19... | Wu Chao, Chen Jun liang, Zhou Bo, Wang Ping long Department of Resources Exploitation Engineering, Central South University of Technology, Changsha 410083, China | 1998 | Journal of Environmental Sciences1998,10,4: | 8 |
| 12 | Cadmium Activates Reactive Oxygen Species-dependent AKT/mT OR and Mitochondrial Apoptotic Pathways in Neuronal Cells显示文摘Objective To examine the role of Cd-induced reactive oxygen species(ROS)generation in the apoptosis of neuronal cells.Methods Neuronal cells(primary rat cerebral cortical neurons and PC12 cells)were incubated with or without Cd post-pretreatment with rapamycin(Rap)or N-acetyl-L-cysteine(NAC).Cell viability was determined by MTT assay,apoptosis was examined using flow cytometry and fluorescence microscopy,and the activation of phosphoinositide 3'-kinase/protein kinase B(Akt)/mammalian target of rapamycin(m TOR)and mitochondrial apoptotic pathways were measured by western blotting or immunofluorescence assays.Results Cd-induced activation of Akt/m TOR signaling,including Akt,m TOR,p70 S6 kinase(p70 S6K),and eukaryotic initiation factor 4E binding protein 1(4E-BP1).Rap,an m TOR inhibitor and NAC,a ROS scavenger,blocked Cd-induced activation of Akt/m TOR signaling and apoptosis of neuronal cells.Furthermore,NAC blocked the decrease of B-cell lymphoma 2/Bcl-2 associated X protein(Bcl-2/Bax)ratio,release of cytochrome c,cleavage of caspase-3 and poly(ADP-ribose)polymerase(PARP),and nuclear translocation of apoptosis-inducing factor(AIF)and endonuclease G(Endo G).Conclusion Cd-induced ROS generation activates Akt/m TOR and mitochondrial pathways,leading to apoptosis of neuronal cells.Our findings suggest that m TOR inhibitors or antioxidants have potential for preventing Cd-induced neurodegenerative diseases. | YUAN Yan WANG Yi HU Fei Fei JIANG Chen Yang ZHANG Ya Jing YANG Jin Long ZHAO Shi Wen GU Jian Hong LIU Xue Zhong BIAN Jian Chun LIU Zong Ping | 2016 | Biomedical and Environmental Sciences2016,29,2: | 8 |
| 13 | Detection of serum IgM and IgG for COVID-19 diagnosis显示文摘Dear Editor,Infection with the novel coronavirus(SARS-CoV-2,which is the virus responsible for the coronavirus disease 2019(COVID-19))was first reported in Wuhan,China on December 31,2019.The outbreak of COVID-19 remains ongoing and was linked to more than 80,000 infected patients and more than 3,000 deaths in China as of March 7,2020(Holshue et al.,2020). | Ling Zhong Junlan Chuan Bo Gong Ping Shuai Yu Zhou Yi Zhang Zhilin Jiang Dingding Zhang Xiaoqi Liu Shi Ma Yi Huang He Lin Qingwei Wang Lulin Huang Dan Jiang Fang Hao Juan Tang Chunqi Zheng Hua Yu Zhibin Wang Qi Jiang Tao Zeng Mei Luo Fanwei Zeng Fanxin Zeng Jianghai Liu Junxi Tian Yu Xu Tengxiang Long Kaiju Xu Xingxiang Yang Yuping Liu Yi Shi Li Jiang Zhenglin Yang | 2020 | Science China(Life Sciences)2020,63,5: | 8 |
| 14 | Emergent Endoscopic Retrograde Cholangiopancreatography with Placement of Biliary Double Stents to Salvage Endoscopic Retrograde Cholangiopancreatography-lnduced Stapfer's Type Ⅱ Perforation显示文摘 | Ping Yue Wen-Bo Meng Joseph W Leung Lei Zhang Xiao-Liang Zhu Hui Zhang Hai-Ping Wang Zheng-Feng Wang Ke-Xiang Zhu Long Miao Wen-Ce Zhou Xun Li | 2018 | Chinese Medical Journal2018,,19: | 7 |
| 15 | Impact of different termination modes on atrial fibrillation termination in catheter ablation of persistent atrial fibrillation显示文摘 | WANG Ping DONG Jian-zeng LONG De-yong NING Man TANG Ri-bo YU Rong-hui XUE Zeng-ming SANG Cai-hua JIANG Chen-xi MA Chang-sheng | 2012 | Chinese Medical Journal2012,,11: | 7 |
| 16 | Toxic activity of a protein complex purified from Xenorhabdus nematophila HB310 to Plutella xylostella larvae显示文摘Xenorhabdus nematophila,属于家庭 Enterobacteriaceae 的克否定的 proteobacterium 并且与土壤 entomopathogenic 线虫共生地联系了, Steinernema carpocapsae,对大量昆虫病原。有杀虫的活动的蛋白质建筑群从房间 ofX 被孤立。外面腌和本国的 polyacrylamide 胶化电气泳动(页) 的 nematophilaHB310 紧张使用方法。七多肽变化 50250 kDa 被钠 dodecyl 硫酸盐(SDS ) 很好与蛋白质建筑群(命名 Xnpt ) 分开其五被帮助矩阵的激光 desorption-time-of-flight 团 spectrometry (MALDI-TOFMS ) 作为 XptA2, xptC1, XptB1, GroEL 和假想蛋白质识别的 -PAGE, 。Xnpt 显示出高口头的毒力到有菱形斑纹的蛾(DBM ) 的幼虫, Plutella xylostellaL。(鳞翅目, Plutellidae ) 作为它对第二和第三中间形态的中部的致命的集中(LC50 ) ,幼虫分别地在 72 h 是 331.45 ng/mL 和 553.59 ng/mL。喂 Xnpt 的 DBM 幼虫的组织学的分析在 midgut 上显示出广泛的组织病理学说的效果。生物化学的分析显示 Xnpt 显著地在 midgut 禁止了三重要的酶的活动。总的来说,我们的数据证明蛋白质建筑群孤立 fromX。nematophilaHB310 由破坏 midgut 纸巾并且禁止 midgut 朊酶活动导致了昆虫的 antifeedant 和死亡。 | Qin-Ying Wang Zi-Yan Nangong Jun Yang Ping Song Yi Wang Liwang Cui Long Cui | 2012 | Insect Science2012,19,3: | 7 |
| 17 | Two new lignans from Dipteronia dyeriana显示文摘新 sesquilignan, 7 鈥 ? 8 鈥 ? didehydroherpetotriol (1 ) ,和新 lignan glycoside,(+)-isolariciresinol-9 鈥 ?O- 伪 -l-rhamnopyranosyl-(1 鈫 ? 6 )- 尾 -d-glucopyranoside (2 ) ,从 Dipteronia dyeriana 的分支被孤立。他们的结构被分光镜的方法和化学证据阐明。与 39 渭 m ol/L 的 IC50 价值对人的白血球过多症 K562 房间加重 1 项拥有的禁止的活动。 | Rong Guo Min Luo Chun Lin Long Ma Lin Li Zhi Qin Ouyang Yi Ping Zhou Yue Hu Wang Xing Yu Li Ya Na Shi | 2008 | Chinese Chemical Letters2008,19,10: | 7 |
| 18 | Geochemistry and Sr-Nd-Pb isotopic characteristics of the Mugouriwang Cenozoic volcanic rocks from Tibetan Plateau:Constraints on mantle source of the underplated basic magma显示文摘The Mugouriwang Cenozoic volcanic rocks exposed in the north Qiangtang Block of Tibetan Plateau are mainly composed of basalt and andesitic-basalt,both characterized by the lower SiO2 (51%―54%),high refractory elements (i.e. Mg,Cr,Ni) as well as the moderate enrichment in light rare earth elements (LREE) relative to a slight depleted in Eu and high strength field elements (HFSE,i.e. Nb,Ta,Ti). Be-sides,the fairly low Sm/Yb value (3.07―4.35) could signify that the rocks should be derived directly from partial melting of the spinel lherzolite at the upper part of the asthenosphere. These rocks have radiogenic Sr and Pb (87Sr/86Sr = 0.705339 to 0.705667; 208Pb/204Pb = 38.8192 to 38.8937; 207Pb/204Pb = 15.6093 to 15.6245; 206Pb/204Pb = 18.6246 to 18.6383),and non-radiogenic Nd (143Nd/144Nd = 0.512604 to 0.512639; εNd = +0.02 to -0.66) in agreement with those values of the BSE mantle reservoir. The DUPAL anomaly of the rocks can be evidently attested by the △8/4Pb = 66.82 to 74.53 ,△7/4Pb = 9.88 to 11.42,△Sr>50,implying that the Mugouriwang volcanic rock is likely to be generated by partial melting of a Gondwana-bearing asthenospheric mantle ever matasomatised by the fluid from subduction zone. Depending on the previous study on the high-K calc-alkaline intermediate-felsic volcanics in the study area,this paper proposed that the fluids derived from the subducted Lhasa Block metasomatised the asthenosphere beneath the Qiangtang Block,and induced its partial melting,and then the melt under-plated the thickened Qiangtang lithosphere and caused the generation of the Cenozoic adakite-like felsic magmas in the Qiangtang region. | LAI ShaoCong QIN JiangFeng LI YongFei LONG Ping | 2007 | Science China Earth Sciences2007,50,7: | 7 |
| 19 | Multiparty-controlled teleportation of an arbitrary GHZ-class state by using a d-dimensional (N+2)-particle nonmaximally entangled state as the quantum channel显示文摘We present a scheme for multiparty-controlled teleportation of an arbitrary high-dimensional GHZ-class state with a d-dimensional (N+2)-particle GHZ state following some ideas from the teleportation (Chinese Physics B, 2007, 16: 2867). This scheme has the advantage of transmitting much fewer particles for controlled teleportation of an arbitrary multiparticle GHZ-class state. Moreover,we discuss the application of this scheme by using a nonmaximally entangled state as its quantum channel. | LONG LiuRong LI HongWei ZHOU Ping FAN Chao YIN CaiLiu | 2011 | Science China(Physics,Mechanics & Astronomy)2011,54,3: | 7 |
| 20 | A THIRD-ORDER BOUSSINESQ MODEL APPLIED TO NONLINEAR EVOLUTION OF SHALLOW-WATER WAVES显示文摘The conventional Boussinesq model is extended to the third order in dispersion and nonlinearity. The new equations are shown to possess better linear dispersion characteristics. For the evolution of periodic waves over a constant depth, the computed wave envelops are spatially aperiodic and skew. The model is then applied to the study of wave focusing by a topographical lens and the results are compared with Whalin′s (1971) experimental data as well as some previous results from the conventional Boussinesq model. Encouragingly, improved agreement with Whalin′s experimental data is found. [WT5”HZ] | Zhang Ying long CCM MINDEF, Department of Mech. and Prod. Eng., National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260 Zhu Song ping Department of Mathematics, the University of Wollongong, Wollongong, NSW 2522, Australia | 2000 | Journal of Hydrodynamics2000,12,2: | 7 |