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| 1 | Inhibitory effects of the extracts with different solvents from three compositae plants on cyanobacterium Microcystis aeruginosas显示文摘The algicidal activity of the terrestrial plants is a novel and promising means for alga control of eutrophic waters.In this study,three compositae plants - Artemisia annua(A.annua),Conyza canadensis(C.canadensis),and Erigeron annuus(E.annuus) were selected and antialgal activity of petroleum ether(PE),ethyl acetate(EA) and ethanol extracts of these plants on blue algae Microcystis aeruginosa was investigated.The result shows the EA extracts of these plants present the stronger inhibitory effects.The results of the further separation of PE and EA extracts according to water-solubility and acidity or alkalinity show that fatty acids and terpenoids in A.annua,terpenoids and organic acid in C.Canadensis and E.Annuus may be the main antialgal active constituents.This study suggested that the EA extracts of these plants could become the potential algicide to prevent water blooming. | NI LiXiao HAO XiangYang LI ShiYin CHEN ShiJin REN GaoXiang ZHU Liang | 2011 | Science China Chemistry2011，54，7： | 7 |
| 2 | Electrochemical reduction of CO_2 in solid oxide electrolysis cells显示文摘The effort on electrochemical reduction of CO_2 to useful chemicals using the renewable energy to drive the process is growing fast recently. In this review, we introduce the recent progresses on the electrochemical reduction of CO_2 in solid oxide electrolysis cells(SOECs). At high temperature, only CO is produced with high current densities and Faradic efficiency while the reactor is complicated and a better sealing technique is urgently needed. The typical electrolytes such as zirconia-based oxides, ceria-based oxides and lanthanum gallates-based oxides, anodes and cathodes are introduced in this review, and the cathode materials, such as conventional metal–ceramics(cermets), mixed ionic and electronic conductors(MIECs) are discussed in detail. In the future, to gain more value-added products, the electrolyte, cathode and anode materials should be developed to allow SOECs to be operated at temperature range of 573–873 K. At those temperatures, SOECs may combine the advantages of the low temperature system and the high temperature system to produce various products with high current densities. | Lixiao Zhang Shiqing Hu Xuefeng Zhu Weishen Yang | 2017 | Journal of Energy Chemistry2017，26，4： | 6 |
| 3 | Design and efficient synthesis of novel haptens and complete antigens for the AOZ,a toxic metabolite of furazolidone显示文摘好策略为设计有效幸运向前被带十并且为 3-amino-2-oxazolidinone (AOZ ) 的完全的抗原。最新设计的 Haptens 被使用 LiCl N (et ) 在好产量轻易地完成 3 同样新的催化作用系统,其结构被光谱学分析阐明,。为 AOZ 的新奇抗原被方便活跃酉旨方法成功地准备。3 和 4 作为 41:1 (5a ) 分别地被证明到搬运人蛋白质的幸运十的比率, 39:1 (6a ) , 11:1 (5b ) 和由 trinitrobenzene 的 9:1 (6b ) 酸性硫酸基的酸(TNBS ) 方法。抗血清的间接竞争 ELISA (ic-ELISA ) 的结果显示十与一个短不饱和的方面锁住的幸运能有效地唤起特定的有免疫力的反应。 | Yu Dong Shen Yu Wang Shi Wei Zhang Zhi LiXiao Yuan Ming Sun Xian Zhang Bu Lian Quan Gu | 2007 | Chinese Chemical Letters2007，18，12： | 5 |
| 4 | A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice,rabbits and NHPs显示文摘The emergence of SARS-CoV-2 variants and potentially other highly pathogenic sarbecoviruses in the future highlights the need for pan-sarbecovirus vaccines.Here,we discovered a new STING agonist,CF501,and found that CF501-adjuvanted RBD-FC vaccine(CF501/RBD-FC)elicited significantly stronger neutralizing antibody(nAb)and T cell responses than Alum-and cGAMP-adjuvanted RBD-FC in mice.Vaccination of rabbits and rhesus macaques(nonhuman primates,NHPs)with CF501/RBD-FC elicited exceptionally potent nAb responses against SARS-CoV-2 and its nine variants and 41 S-mutants,SARS-CoV and bat SARSr-CoVs.CF501/RBD-FC-immunized hACE2-transgenic mice were almost completely protected against SARS-CoV-2 challenge,even 6 months after the initial immunization.NHPs immunized with a single dose of CF501/RBD-FC produced high titers of nAbs.The immunized macaques also exhibited durable humoral and cellular immune responses and showed remarkably reduced viral load in the upper and lower airways upon SARS-CoV-2 challenge even at 108 days post the final immunization.Thus,CF501/RBD-Fc can be further developed as a novel pan-sarbecovirus vaccine to combat current and future outbreaks of sarbecovirus diseases. | Zezhong Liu Jie Zhou Wei Xu Wei Deng Yanqun Wang Meiyu Wang Qian Wang Ming Hsieh Jingming Dong Xinling Wang Weijin Huang Lixiao Xing Miaoling He Chunlin Tao Youhua Xie Yilong Zhang Youchun Wang Jincun Zhao Zhenghong Yuan Chuan Qin Shibo Jiang Lu Lu | 2022 | Cell Research2022，32，3： | 5 |
| 5 | North Pacific Eastern Subtropical Mode Water simulation and future projection显示文摘The present climate simulation and future projection of the Eastern Subtropical Mode Water(ESTMW) in the North Pacific are investigated based on the Geophysical Fluid Dynamics Laboratory Earth System Model(GFDL-ESM2M). Spatial patterns of the mixed layer depth(MLD) in the eastern subtropical North Pacific and the ESTMW are well simulated using this model. Compared with historical simulation, the ESTMW is produced at lighter isopycnal surfaces and its total volume is decreased in the RCP8.5 runs, because the subduction rate of the ESTMW decreases by 0.82×10-6 m/s during February–March. In addition, it is found that the lateral induction decreasing is approximately four times more than the Ekman pumping, and thus it plays a dominant role in the decreased subduction rate associated with global warming. Moreover, the MLD during February–March is banded shoaling in response to global warming, extending northeastward from the east of the Hawaii Islands(20°N, 155°W) to the west coast of North America(30°N, 125°W), with a maximum shoaling of 50 m, and then leads to the lateral induction reduction. Meanwhile, the increased northeastward surface warm current to the east of Hawaii helps strengthen of the local upper ocean stratification and induces the banded shoaling MLD under warmer climate. This new finding indicates that the ocean surface currents play an important role in the response of the MLD and the ESTMW to global warming. | XIA Ruibin LIU Qinyu XU Lixiao LU Yiqun | 2015 | Acta Oceanologica Sinica2015，34，3： | 5 |
| 6 | A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases显示文摘The development of broad-spectrum antivirals against human coronaviruses(HCoVs)is critical to combat the current coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and its variants,as well as future outbreaks of emerging CoVs.We have previously identified a polyethylene glycol-conjugated(PEGylated)lipopeptide,EK1C4,with potent pan-CoV fusion inhibitory activity.However,PEG linkers in peptide or protein drugs may reduce stability or induce anti-PEG antibodies in vivo.Therefore,we herein report the design and synthesis of a series of dePEGylated lipopeptide-based pan-CoV fusion inhibitors featuring the replacement of the PEG linker with amino acids in the heptad repeat 2 C-terminal fragment(HR2-CF)of HCoV-OC43.Among these lipopeptides,EKL1C showed the most potent inhibitory activity against infection by SARS-CoV-2 and its spike(S)mutants,as well as other HCoVs and some bat SARS-related coronaviruses(SARSr-CoVs)tested.The dePEGylated lipopeptide EKL1C exhibited significantly stronger resistance to proteolytic enzymes,better metabolic stability in mouse serum,higher thermostability than the PEGylated lipopeptide EK1C4,suggesting that EKL1C could be further developed as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases. | Jie Zhou Wei Xu Zezhong Liu Chao Wang Shuai Xia Qiaoshuai Lan Yanxing Cai Shan Su Jing Pu Lixiao Xing Youhua Xie Lu Lu Shibo Jiang Qian Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 5 |
| 7 | CitGVD:a comprehensive database of citrus genomic variations显示文摘Citrus is one of the most important commercial fruit crops worldwide.With the vast genomic data currently available for citrus fruit,genetic relationships,and molecular markers can be assessed for the development of molecular breeding and genomic selection strategies.In this study,to permit the ease of access to these data,a web-based database,the citrus genomic variation database(CitGVD,http://gffzz1758061741e3440chk6509fxpb5nq6v5b.ffgz.tsg.suse.edu.cn/home)was developed as the first citrusspecific comprehensive database dedicated to genome-wide variations including single nucleotide polymorphisms(SNPs)and insertions/deletions(INDELs).The current version(V1.0.0)of CitGVD is an open-access resource centered on 1,493,258,964 high-quality genomic variations and 84 phenotypes of 346 organisms curated from in-house projects and public resources.CitGVD integrates closely related information on genomic variation annotations,related gene annotations,and details regarding the organisms,incorporating a variety of built-in tools for data accession and analysis.As an example,CitGWAS can be used for genome-wide association studies(GWASs)with SNPs and phenotypic data,while CitEVOL can be used for genetic structure analysis.These features make CitGVD a comprehensive web portal and bioinformatics platform for citrus-related studies.It also provides a model for analyzing genome-wide variations for a wide range of crop varieties. | Qiang Li Jingjing Qi Xiujuan Qin Wanfu Dou Tiangang Lei Anhua Hu Ruirui Jia Guojin Jiang Xiuping Zou Qin Long Lanzhen Xu Aihong Peng Lixiao Yao Shanchun Chen Yongrui He | 2020 | Horticulture Research2020，7，1： | 4 |
| 8 | Enclosed stigma contributes to higher spikelet fertility for rice(Oryza sativa L.) subjected to heat stress显示文摘With global warming, rice plants may be subjected to heat stress more regularly during the heatsensitive flowering stage, causing spikelet sterility and grain yield loss.Stigma exsertion is considered to increase pollen reception and promote female reproductive success.The aim of this study was to investigate the role of stigma exsertion on spikelet fertility at high temperatures.Five rice cultivars(Liangyoupeijiu, Shanyou 63, Huanghuazhan, Nagina 22, and IR64) with differing degrees of stigma exsertion were cultivated and exposed to high temperature at anthesis.Heat-tolerant cultivars did not always show a high percentage of spikelets with exserted stigmas, and vice versa.Irrespective of the presence of more pollen grains on exserted stigmas, spikelets with exserted stigmas did not show greater spikelet fertility than spikelets with fewer exserted stigmas or hidden stigmas under heat stress.GA3 application augmented the percentage of spikelets with exserted stigmas;however, it did not increase spikelet fertility under heat stress.Spikelet fertility of whole panicles was negatively correlated with the percentage of spikelets with exserted stigmas, but positively with that with hidden stigmas.Viability of the hidden stigmas was less reduced than that of exserted stigmas under heat stress, suggesting that hidden stigmas have an advantage in maintaining viability.Heat stress delayed anther dehiscence and reduced the viabilities of both exserted stigmas and pollens, thereby causing low spikelet fertility.Together, these results suggest that high spikelet fertility does not depend on stigma exsertion and that enclosed stigma generally contributes to higher spikelet fertility and heat tolerance under high-temperature conditions during flowering in rice. | Chao Wu Kehui Cui Qiuqian Hu Wencheng Wang Lixiao Nie Jianliang Huang Shaobing Peng | 2019 | The Crop Journal2019，7，3： | 4 |
| 9 | OsAM1 is required for leptotene-zygotene transition in rice显示文摘发生在成熟分裂的发作的事件充分没被阐明。在现在的学习, OsAM1 被基于地图的克隆在米饭(Oryza sativa L.) 识别。OsAM1, Arabidopsis SWI1 的一个相当或相同的事物和玉米 AM1,与一个卷卷领域把蛋白质编码为它的中央区域。在 Osam1 异种,花粉母亲房间在 leptotene 被逮捕,证明 OsAM1 为 leptotene-zygotene 转变被要求。Immunocytological 分析表明 OsAM1 在早前期作为 foci 存在我 meiocytes。很微弱的 OsREC8 foci 在 Osam1 异种坚持了,显示 OsAM1 没为 OsREC8 的起始的 meiotic 招募被要求。当 OsAM1 不在时,包括 PAIR2, ZEP1 和 OsMER3,许多另外的批评 meiotic 部件不能正确地被安装到染色体上。在 pair2, Osmer3 和 zep1 异种,相反, OsAM1 能通常被装载,建议 OsAM1 起造在成熟分裂的开始的合适的染色体结构里的一个基本作用。 | Lixiao Che Ding Tang Kejian Wang Mo Wang Keming Zhu Hengxiu Yu Minghong Gu Zhukuan Cheng | 2011 | Cell Research2011，21，4： | 4 |
| 10 | Cloning and Expression Analysis of Citrus Genes Cs GH3.1 and Cs GH3.6Responding to Xanthomonas axonopodis pv. citri Infection显示文摘To study the functions of the early auxin-responsive genes Cs GH3.1 and Cs GH3.6 in citrus resistance against canker disease, we cloned Cs GH3.1and Cs GH3.6 in ‘Newhall' Navel Orange(Citrus sinensis Osbeck). They are 1 797 bp and 1 887 bp and encode 598 and 629 amino acids, respectively. In vitro mature leaves from susceptible ‘Newhall' and resistant Calamondin(C. madurensis) were inoculated by a Xanthomonas axonopodis pv. citri(Xac) bacterial suspension, and expression of Cs GH3.1 and Cs GH3.6 in the two varieties were analyzed using quantitative real-time PCR(q RT-PCR). ‘Newhall' leaves were treated with different hormones for 3 days, inoculated by Xac bacterial suspension, and then the symptoms in these leaves were investigated. We used q RT-PCR to analyze the effect of different hormones on Cs GH3.1 and Cs GH3.6 expression in ‘Newhall'leaves. The expression levels of both Cs GH3.1 and Cs GH3.6 were significantly induced by Xac in ‘Newhall' leaves, compared with levels in Calamondin leaves. 1-naphthy acetic acid(NAA) increased the hypertrophy of infection sites in ‘Newhall' leaves, while naphthyl-phthalamic acid(NPA)had no visible effect on lesion development. NAA hormone greatly improved expression of Cs GH3.1 in ‘Newhall', but not Cs GH3.6. These results indicate that the auxin primary-response gene Cs GH3.1 plays an important role in citrus susceptibility to Xac. | CHEN Min HE Yongrui XU Lanzhen PENG Aihong LEI Tiangang YAO Lixiao LI Qiang ZHOU Pengfei BAI Xiaojing DUAN Minjie JIANG Xueyou JIA Ruirui ZOU Xiuping CHEN Shanchun | 2016 | Horticultural Plant Journal2016，2，4： | 4 |
| 11 | Correlation of Leaf and Root Senescence During Ripening in Dry Seeded and Transplanted Rice显示文摘Dry seeding is a resource-saving rice establishment method. With an equivalent yield, dry seeded flooded rice(DSR) has been considered as a replacement for traditional transplanted flooded rice(TFR). However, the differences in leaf and root senescence during grain filling between DSR and TFR were seldom identified. In this study, the root length, root tip number and leaf senescence of rice varieties Huanghuazhan and Yangliangyou 6 during ripening were compared between DSR and TFR. Results showed that top three leaves in DSR had the characteristics of relatively lower SPAD value, lower N content and premature leaf senescence. In addition, both the total root length and total root tip number of DSR were significantly lower than those of TFR. In conclusion, premature and quick leaf senescence was related with inadequate root length and root tip number during ripening, which might result from the deficiency of nitrogen supply in DSR. Techniques on improving leaf nitrogen status and delaying the leaf senescence during grain-filling in DSR should be developed in future researches. | LIU Hongyan WANG Weiqin HE Aibin NIE Lixiao | 2018 | Rice science2018，25，5： | 4 |
| 12 | Recent advances in high-loading catalysts for low-temperature fuel cells: From nanoparticle to single atom显示文摘Low-temperature fuel cells(LTFCs)are considered to be one of the most promising power sources for widespread application in sustainable and renew-able energy conversion technologies.Although remarkable advances have been made in the mass activity of catalysts,mass transport impedance needs to be urgently addressed at a well-designed membrane electrode assembly(MEA)scale.Increasing the loading of electrocatalysts is conducive to prepare thinner and more efficient MEAs owing to the resulting enhanced reactant permeability,better proton diffusion,and lower electrical resistance.Herein,recent progress in high-loading(≥40 wt.%)Pt nanoparticle catalysts(NPCs)and high-loading(≥2 wt.%)single-atom catalysts(SACs)for LTFC applications are reviewed.A summary of various synthetic approaches and support materials for high-loading Pt NPCs and SACs is systematically presented.The influences of high surface area and appropriate surface functionalization for Pt NPCs,as well as coordina-tion environment,spatial confinement effect,and strong metal-support interac-tions(SMSI)for SACs are highlighted.Additionally,this review presents some ideas regarding challenges and future opportunities of high-loading catalysts in the application of LTFCs. | Lixiao Shen Miao Ma Fengdi Tu Zigang Zhao Yunfei Xia Kokswee Goh Lei Zhao Zhenbo Wang Guangjie Shao | 2021 | SusMat2021，1，4： | 3 |
| 13 | Effect of slope inclination on step friction coefficient of human being显示文摘Effect of slope inclination on step friction coefficient of human being was studied by gait friction tester developed by Henan University of Science and Technology.It is beneficial to improving the safety of human beings while walking on a ramp.Based on the trajectory of mass center of body(MCOB)and the mechanical analysis of human body while walking,conclusion could be drawn that the required step frictional coefficient(RSFC)exhibited an'M'shaped curve during the foot contacting with the ground and got its maximum and minimum values when MCOB of the subject was at the highest and lowest position respectively.Moreover,the first peak of RSFC decreases firstly and then increases,while the second peak of RSFC increases with the increase of slope inclination at the experimental condition.The position of pivotal point is decided by the relative size of slope inclination and the angle between the plumb line through MCOB and the line from foot to MCOB. | ZHANG YongZhen JIA LiXiao PANG XianJuan NIU YongPing DU SanMing | 2013 | Science China(Technological Sciences)2013，56，12： | 3 |
| 14 | Response of Mode Water and Subtropical Countercurrent to Greenhouse Gas and Aerosol Forcing in the North Pacific显示文摘The response of the North Pacific Subtropical Mode Water and Subtropical Countercurrent (STCC) to changes in greenhouse gas (GHG) and aerosol is investigated based on the 20th-century historical and single-forcing simulations with the Geo-physical Fluid Dynamics Laboratory Climate Model version 3 (GFDL CM3). The aerosol effect causes sea surface temperature (SST) to decrease in the mid-latitude North Pacific, especially in the Kuroshio Extension region, during the past five decades (1950-2005), and this cooling effect exceeds the warming effect by the GHG increase. The STCC response to the GHG and aerosol forcing are opposite. In the GHG (aerosol) forcing run, the STCC decelerates (accelerates) due to the decreased (increased) mode waters in the North Pacific, resulting from a weaker (stronger) front in the mixed layer depth and decreased (increased) subduction in the mode water formation region. The aerosol effect on the SST, mode waters and STCC more than offsets the GHG effect. The response of SST in a zonal band around 40?N and the STCC to the combined forcing in the historical simulation is similar to the response to the aerosol forcing. | WANG Liyi LIU Qinyu XU Lixiao XIE Shang-Ping | 2013 | Journal of Ocean University of China2013，12，2： | 3 |
| 15 | Forming of magnesium alloy microtubes in the fabrication of biodegradable stents显示文摘Magnesium alloys have, in recent years, been recognized as highly promising biodegradable materials, especially for vascular stent applications. Forming of magnesium alloys into high-precision thin-wall tubes has however presented a technological barrier in the fabrication of vascular stents, because of the poor workability of magnesium at room temperature. In the present study, the forming processes, i.e., hot indirect extrusion and multi-pass cold drawing were used to fabricate seamless microtubes of a magnesium alloy. The magnesium alloy ZM21 was selected as a representative biomaterial for biodegradable stent applications. Microtubes with an outside diameter of 2.9 mm and a wall thickness of 0.2 mm were successfully produced at the fourth pass of cold drawing without inter-pass annealing. Dimensional evaluation showed that multipass cold drawing was effective in correcting dimensional non-uniformity arising from hot indirect extrusion. Examinations of the microstructures of microtubes revealed the generation of a large number of twins as a result of accumulated work hardening at the third and fourth passes of cold drawing, corresponding to the significantly raised forming forces. The work demonstrated the viability of the forming process route selected for the fabrication of biodegradable magnesium alloy microtubes. | Lixiao Wang Gang Fang Lingyun Qian Sander Leeflang Jurek Duszczyk Jie Zhou | 2014 | Progress in Natural Science:Materials International2014，24，5： | 2 |
| 16 | Cost of non-renewable energy in production of wood pellets in China显示文摘因为生产,估计被宣称可更新的所有简历燃料事实上可更新的对程度是必要的如此的可更新的燃料本身要求非可更新的精力(NE ) 和材料的某数量。用混合生命周期分析( LCA )一[欧元]“从原料收集到到结束 usersa 的小团的交货[欧元]”在中国的木头小团生产的精力费用在 1.35 J/J ,仅仅 0.09 J 从 NE 被导出被估计,显示仅仅 NE 的 0.09 J 被要求交付可更新的精力的 1 J 进社会并且证明这个过程真正是可更新的。大多数 NE 在变换过程(46.21%) 和小团的交货期间被消费到终端用户(40.69%) ,在哪个电和柴油机期间 NE 的二种主要形式分别地被使用。敏感分析证明小团在上被搬运的距离显著地影响 NE 的费用。因此木头资源是可得到的终端市场和这个地点的地点对节省柴油机关键[出版摘要] | Changbo WANG Lixiao ZHANG Jie LIU | 2013 | Frontiers of Earth Science2013，7，2： | 2 |
| 17 | Fast and Slow Responses of the North Pacific Mode Water and Subtropical Countercurrent to Global Warming显示文摘Six coupled general circulation models from the Coupled Model Intercomparison Project Phase 5 (CMIP5) are em-ployed for examining the full evolution of the North Pacific mode water and Subtropical Countercurrent (STCC) under global warming over 400 years following the Representative Concentration Pathways (RCP) 4.5. The mode water and STCC first show a sharp weakening trend when the radiative forcing increases, but then reverse to a slow strengthening trend of smaller magnitude after the radiative forcing is stablized. As the radiative forcing increases during the 21st century, the ocean warming is surface-intensified and decreases with depth, strengthening the upper ocean's stratification and becoming unfavorable for the mode water formation. Moving southward in the subtropical gyre, the shrinking mode water decelerates the STCC to the south. After the radiative forcing is stabilized in the 2070s, the subsequent warming is greater at the subsurface than at the sea surface, destabilizing the upper ocean and becoming favorable for the mode water formation. As a result, the mode water and STCC recover gradually after the radiative forc-ing is stabilized. | XU Lixiao XIE Shang-Ping LIU Qinyu | 2013 | Journal of Ocean University of China2013，12，2： | 2 |
| 18 | A Class of Solvable Lie Algebras and Their Hom-Lie Algebra Structures显示文摘The finite-dimensional indecomposable solvable Lie algebras s with Q2n+1as their nilradical are studied and classified, it turns out that the dimension of s is dim Q2n+1+1.Then the Hom-Lie algebra structures on solvable Lie algebras s are calculated. | LIXiao—chao LI Dong-ya JIN Quan-qin | 2014 | Chinese Quarterly Journal of Mathematics2014，29，2： | 2 |
| 19 | Mechanism and Modeling for Polymerization of Acrylamide in Inverse Microemulsions显示文摘After discussion on the mechanism of polymer particle nucleation and growth in inverse microemulsion polymerization, a schematic physical model for polymerization of acrylamide in inverse microemulsions was presented. Furthermore, several key problems in mathematically modeling of inverse microemulsion polymerization were pointed out. | LiXiao ZhangWeiying YuanHuigen | 2004 | 工程科学(英文版)2004，2，2： | 1 |
| 20 | Researchprogressofwaterbornepolyurethanemodifiedbypolyacrylate[J]显示文摘 | ChenJianfu(陈建福) LiXiao(李晓) ZhangWeiying(张卫英) CaiJinxiang(蔡锦香) | | 中国胶黏剂0，，： | 1 |
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