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4篇 您的检索式:作者名="Sander Leeflang"
    题名 作者 年代 出处 被引量
1Forming of magnesium alloy microtubes in the fabrication of biodegradable stents显示文摘Magnesium alloys have, in recent years, been recognized as highly promising biodegradable materials, especially for vascular stent applications. Forming of magnesium alloys into high-precision thin-wall tubes has however presented a technological barrier in the fabrication of vascular stents, because of the poor workability of magnesium at room temperature. In the present study, the forming processes, i.e., hot indirect extrusion and multi-pass cold drawing were used to fabricate seamless microtubes of a magnesium alloy. The magnesium alloy ZM21 was selected as a representative biomaterial for biodegradable stent applications. Microtubes with an outside diameter of 2.9 mm and a wall thickness of 0.2 mm were successfully produced at the fourth pass of cold drawing without inter-pass annealing. Dimensional evaluation showed that multipass cold drawing was effective in correcting dimensional non-uniformity arising from hot indirect extrusion. Examinations of the microstructures of microtubes revealed the generation of a large number of twins as a result of accumulated work hardening at the third and fourth passes of cold drawing, corresponding to the significantly raised forming forces. The work demonstrated the viability of the forming process route selected for the fabrication of biodegradable magnesium alloy microtubes.Lixiao Wang Gang Fang Lingyun Qian Sander Leeflang Jurek Duszczyk Jie Zhou 2014Progress in Natural Science:Materials International2014,24,5:2
2Multipass cold drawing of magnesium alloy minitubes for biodegradable vascular stents显示文摘Gang Fang Wei-jiang Ai Sander Leeflang Jurek Duszczyk Jie Zhou 2013Materials Science & Engineering C2013,,6:1
3Muhipass Cold Drawing of Magnesium Alloy Minitubes for Biodegradable Vascular Stents 显示文摘FANG Gang AI Wei-jiang LEEFLANG Sander 2013Materials Science & Engineering C2013,,:1
43D printed titanium scaffolds with ordered TiO_(2) nanotubular surface and mesoporous bioactive glass for bone repair显示文摘Titanium alloy scaffolds have recently gained substantial interest for the treatment of critical-size bone defect,particularly along with the maturity of the 3D printing technology that is capable of turning scaffold design ideas into real implants.As titanium alloys lack surface osteogenic activity,for improved biological performance of such scaffolds,surface modification is necessary.Various coating materials and coating methods have been explored.In this study,we developed a unique surface modification method to provide the surface of 3D printed titanium scaffolds with nano-sized structure and bioactive agent.Uniform,ordered TiO2 nanotube arrays were formed by applying two-step anodization,and then mesoporous bioactive glass(MBG)was loaded into nanotubes.The results of in vitro immersion testing showed that bioactive ions,i.e.,Si and Ca ions,could be steadily and continuously released from MBG into basal medium.The assessment of the responses of hBMSCs confirmed that the surface-modified scaffolds supported the adhesion and proliferation of hBMSCs,indicating good surface cytocompatibility.The developed method of combining surface nanostructure and bioactive agent could be used as a new strategy to improve the osteogenic activity of 3D printed titanium alloy scaffolds.Pengyu Zhao Yaqin Liu Tian Li Yanling Zhou Sander Leeflang Lei Chen Chengtie Wu Jie Zhou Zhiguang Huan 2020Progress in Natural Science:Materials International2020,30,4:1
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