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| 1 | Inhibition of metastasis-associated lung adenocarcinoma transcript 1 in CaSki human cervical cancer cells suppresses cell proliferation and invasion显示文摘(MALAT1 ) 联系转移的肺腺癌抄本 1 被建议是一长(7 kb ) 非编码的 RNA。MALAT1 是在许多人的癌的 overexpressed,但是它的功能仍然保持未知。在人的颈的癌症前进调查 MALAT1 的角色,我们设计了并且使用了短发卡 RNA 在 CaSki 房间禁止 MALAT1 表示并且在房间增长和侵略上验证了它的效果。在基因表示的变化被反向的 transcriptasepolymerase 链反应分析。我们的数据证明 MALAT1 通过基因表示的规定涉及颈的癌症房间生长,房间周期前进,和侵略,例如 caspase-3, -8, Bax, Bcl-2,和 Bcl-xL,建议 MALAT1 能有在颈的癌症生物学的重要含意。我们的调查结果在颈的癌症前进说明 MALAT1 的生物意义并且提供 MALAT1 可以在人的颈的癌症的预防作为一个治疗学的目标服务的新奇证据。 | Fengjie Guo Yalin Li Yan Liu Jiajia Wang Yuehui Li Guancheng Li | 2010 | Acta Biochimica et Biophysica Sinica2010，42，3： | 89 |
| 2 | Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome based on NMR techniques显示文摘Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome has been performed by comparison with those of normal rats based on NMR techniques. The relative contents of formate,creatinine,2-oxoglutarate(2-OG) ,citrate,taurine,trimethylamine-N-oxide(TMAO) ,succinate and hippurate in the urine of the rats with Qi deficiency and blood stasis syndrome have been changed. These results have provided evidence for understanding the mechanism and the therapy of Qi defi-ciency and blood stasis syndrome. | LI Lin WANG JianNong REN JianXun XIANG JunFeng TANG YaLin LIU JianXun HANDing | 2007 | Chinese Science Bulletin2007，52，22： | 21 |
| 3 | Apelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2 pathway显示文摘 | Bo Bai Jiyou Tang Haiqing Liu Jing Chen Yalin Li Wengang Song | 2008 | Acta Biochimica et Biophysica Sinica2008，40，4： | 14 |
| 4 | Danggui Buxue decoction ameliorates lipid metabolic defects involved in the initiation of diabetic atherosclerosis;identification of active compounds显示文摘OBJECTIVE: To determine the constituent compounds of Danggui buxue decoction(DBD) involved and the potential mechanisms mediating its effects, with specific reference to lipids playing a role in the initiation of diabetic atherosclerosis.METHODS: Liquid chromatography-tandem mass spectrometry was used to identify and quantify the absorbed bioactive compounds(ABCs) present in DBD. Goto-Kakizaki(GK) rats were randomly allocated to a diabetes atherosclerosis(DA) group, a DBD group, and an ABC group(10 per group), which were all high-fat diet-fed. The treated rats were administered DBD(4 g/kg) or ABCs(in amounts equal to those present in DBD) once daily for 28 d, and a control group of Wistar rats were administered vehicle. Body mass gain, fasting blood glucose, and homeostasis assessment of insulin resistance(HOMAIR) were measured. Serum triglyceride(TG), cholesterol(CHOL), high density lipoprotein-cholesterol(HDL-C), low-density lipoprotein-cholesterol(LDLC) and tumor necrosis factor-α(TNF-α) concentrations were determined. Hematoxylin and eosin staining and microscopy were used to characterize the abdominal aorta and the expression of lipogenic genes was quantified in this vessel.RESULTS: Seven ABCs were identified in rat serum:ferulic acid, formononetin, calycosin, astragaloside,caffeic acid, ligustilide, and butyphthalide. DBD significantly reduced HOMA-IR, the serum concentrations of TG, CHOL, and LDL-C, and the expression of the lipogenic genes monocyte chemotactic protein1, Fas, intercellular adhesion molecule 1, and Cd36 in aorta;and significantly increased the mRNA expression of Scd1 in aorta.CONCLUSION: DBD affects lipid metabolism in the early stage of atherosclerosis in diabetic GK rats,with the mechanism likely involving the regulation of lipid metabolic genes in vessels. The contribution of ABCs to the effect of DBD on lipid metabolism was 24%-101%. | Xue Mei Bian Yong Liu Yalin Zhou Junjie Xu Jianjun Zhang Liang Huang Xi | 2020 | Journal of Traditional Chinese Medicine2020，40，3： | 13 |
| 5 | Interactive effects of soil temperature and moisture on soil N mineralization in a Stipa krylovii grassland in Inner Mongolia, China显示文摘Determining soil N mineralization response to soil temperature and moisture changes is challenging in the field due to complicated effects from other factors. In the laboratory, N mineralization is highly dependent on temperature, moisture and sample size. In this study, a laboratory incubation experiment was carefully designed and conducted under controlled conditions to examine the effects of soil temperature and moisture on soil N mineralization using soil samples obtained from the Stipa krylovii grassland in Inner Mongolia, China. Five temperature(i.e. 9°C, 14°C, 22°C, 30°C and 40°C) and five moisture levels(i.e. 20%, 40%, 60%, 80% and 100% WHC, where WHC is the soil water holding capacity) were included in a full-factorial design. During the 71-day incubation period, microbial biomass carbon(MBC), ammonium nitrogen(NH4 +-N) and nitrate nitrogen(NO3--N) were measured approximately every 18 days; soil basal respiration for qCO2 index was measured once every 2 days(once a week near the end of the incubation period). The results showed that the mineral N production and net N mineralization rates were positively correlated with temperature; the strongest correlation was observed for temperatures between 30°C and 40°C. The relationships between moisture levels and both the mineral N production and net N mineralization rates were quadratic. The interaction between soil temperature and moisture was significant on N mineralization, i.e. increasing temperatures(moisture) enhanced the sensitivity of N mineralization to moisture(temperature). Our results also showed a positive correlation between the net nitrification rate and temperature, while the correlation between the NH4 +-N content and temperature was insignificant. The net nitrification rate was negatively correlated with high NH4 +-N contents at 80%–100% WHC, suggesting an active denitrification in moist conditions. Moreover, qCO2 index was positively correlated with temperature, especially at 80% WHC. With a low net nitrification rate and high soil basal respiration rate, it was likely that the denitrification concealed the microbial gross mineralization activity; therefore, active soil N mineralization occurred in 60%–80% WHC conditions. | Yue LI YingHui LIU YaLin WANG Lei NIU Xia XU YuQiang TIAN | 2014 | Journal of Arid Land2014，6，5： | 12 |
| 6 | Double-composite rectangular truss bridge and its joint analysis显示文摘This paper describes a novel composite tubular truss bridge with concrete slab and concrete-filled rectangular chords. With concrete slab plus truss system and joints reinforced with concrete and Perfobond Leiste rib, double composite truss bridge proved to be a fairly suitable solution in negative moment area. Perfobond Leiste shear connector(PBL) is widely implemented in the composite structure for its outstanding fatigue resistance. In this pilot bridge, Perfobond Leister ribs(PBR) were installed in the truss girder's joints,which played double roles as shear connector and stiffener. An erection method and overall bridge structural analysis were then presented. Typical joints in the pilot bridge were selected to analyze the effect of PBR. Investigation of the effect of PBR in concretefilled tubular joints was elaborated. Comparison has revealed that concrete-filled tubular joints with PBR have much higher constraint capability than joints without PBR. For rectangular tubular truss, the punching shear force of the concrete filled joint with PBR is approximately 43% larger than that of the joint without PBR. Fatigue performance of the joint installed with PBR was improved, which was found through analysis of the stress concentration factor of joint. The PBR installed in the joints mitigated the stress concentration factor in the chord face. Therefore, the advantages of this new type of bridge are demonstrated, including the convenience of construction using rectangular truss, innovative concept of structural design and better global and local performances. | Yongjian Liu Zhihua Xiong Yalin Luo Gao Cheng Ge Liu Jian Yang | 2015 | Journal of Traffic and Transportation Engineering(English Edition)2015，2，4： | 8 |
| 7 | Detection of periodontal pathogens in the patients with aortic aneurysm显示文摘 | Ding Fang Lyu Yalin Han Xiao Zhang Hai Liu Dongyu Hei Wei Liu Yinhua | 2014 | Chinese Medical Journal2014，，23： | 6 |
| 8 | Insulating materials for realising carbon neutrality:Opportunities,remaining issues and challenges显示文摘The 2050 carbon-neutral vision spawns a novel energy structure revolution,and the construction of the future energy structure is based on equipment innovation.Insulating material,as the core of electrical power equipment and electrified transportation asset,faces unprecedented challenges and opportunities.The goal of carbon neutral and the urgent need for innovation in electric power equipment and electrification assets are first discussed.The engineering challenges constrained by the insulation system in future electric power equipment/devices and electrified transportation assets are investigated.Insulating materials,including intelligent insulating material,high thermal conductivity insulating material,high energy storage density insulating material,extreme environment resistant insulating material,and environmental-friendly insulating material,are cat-egorised with their scientific issues,opportunities and challenges under the goal of carbon neutrality being discussed.In the context of carbon neutrality,not only improves the understanding of the insulation problems from a macro level,that is,electrical power equipment and electrified transportation asset,but also offers opportunities,remaining issues and challenges from the insulating material level.It is hoped that this paper en-visions the challenges regarding design and reliability of insulations in electrical equipment and electric vehicles in the context of policies towards carbon neutrality rules.The authors also hope that this paper can be helpful in future development and research of novel insulating materials,which promote the realisation of the carbon-neutral vision. | Chuanyang Li Yang Yang Guoqiang Xu Yao Zhou Mengshuo Jia Shaolong Zhong Yu Gao Chanyeop Park Qiang Liu Yalin Wang Shakeel Akram Xiaoliang Zeng Yi Li Fangwei Liang Bin Cui Junpeng Fang Lingling Tang Yulin Zeng Xingtao Hu Jiachen Gao Giovanni Mazzanti Jinliang He Jianxiao Wang Davide Fabiani Gilbert Teyssedre Yang Cao Feipeng Wang Yunlong Zi | 2022 | High Voltage2022，7，4： | 4 |
| 9 | Thermoelectric properties of In-Hg co-doping in SnTe:Energy band engineering显示文摘Synergistic effect of band convergence and resonant level could be manipulated in SnTe by co-doping In and Hg,leading to a potential thermoelectric performance enhancement in a much wider temperature range.In this work we carefully investigated thermoelectric properties of the In-Hg co-doped SnTe,synthesized by a hot pressing method.With this co-doping the Seebeck coefficients of the co-doped samples were greatly improved(over 50 mVK^(-1))at the room temperature.Although power factors of the In-Hg co-doped SnTe were also able to be optimized,the peak ZT(0.9 at 850 K in Sn_(0.98)Bi_(0.02)Te-1%HgInTe_(2)),however,is not high enough when comparing to other co-doped SnTe systems.This may be caused by the relatively high lattice thermal conductivity.An apparent competition between band convergence doping and resonant level doping was observed in our experiment.The results suggest that band engineering via co-doping should be further understood in order to optimize the thermoelectric properties inside the material system. | Xiaofang Tan Guoqiang Liu Jingtao Xu Xiaojian Tan Hezhu Shao Haoyang Hu Haochuan Jiang Yalin Lu Jun Jiang | 2018 | Journal of Materiomics2018，4，1： | 3 |
| 10 | Effects of Qizhukangxian granules on idiopathic pulmonary fibrosis:a randomized,double blind,placebo-controlled and multicenter clinical pilot trial显示文摘OBJECTIVE:To evaluate the effects of Qizhukangxian granules(QG)on idiopathic pulmonary fibrosis(IPF).METHODS:This is a randomized,double blind,placebo-controlled and multicenter clinical pilot trial.Six medical centers in Tianjin,China,participated in the study.A total of 120 IPF patients were enrolled and randomized into two groups,with 60 patients in each group.The treatment group was treated with QG,while the control group received a Qizhukangxian placebo.The pharmacological treatment lasted for 48 weeks from the enrollment date.The indexes of patients were recorded on the admission day and at the end of the 24th and 48th weeks.Data were analyzed to study the effects of QG;forced vital capacity,change in forced vital capacity and maximal 6-min walk test(6MWT)distance were the primary endpoints.Secondary endpoints were percentage of patients with episodes of acute exacerbation of IPF,pulmonary function,changes in pulse oxygen saturation during the 6MWT,dyspnea score,St.George's respiratory questionnaire score,arterial blood gas analyses and the total Traditional Chinese Medicine symptom pattern score.RESULTS:After 24 weeks of treatment,QG showed greater efficacy than the placebo in certain parameters,including the dyspnea score,Traditional Chinese Medicine symptom pattern score and some indicators in the St.George's respiratory questionnaire score.Analysis of the indexes obtained from all patients at the end of the 48th week showed that the therapeutic effects in the treatment group were significantly better than those in the control group because remarkable differences were observed in most of the primary and secondary endpoints between the two groups,except for the maximal distance of the 6MWT and arterial blood gas analyses.No adverse reaction was observed in either group during the 48-week trial treatment period.CONCLUSION:QG could effectively treat IPF patients by ameliorating pulmonary function,improving the quality of life and lowering the percentage of acute exacerbations. | Guo Sijia Song Yalin Feng Jihong Liu Shuang Li Yuechuan Liu Min Wei Luqing Zhang Xian Xie Hui Sun Zengtao | 2020 | Journal of Traditional Chinese Medicine2020，40，4： | 3 |
| 11 | New practice in semaglutide on type-2 diabetes and obesity:clinical evidence and expectation显示文摘Obesity is an important risk factor of type 2 diabetes(T2D),which has become an important factor threatening human health.However,no perfect drug choice for obesity exists.Semaglutide is a kind of human glucagon-like peptide-1(GLP-1)analog that promotes insulin secretion while inhibiting glucagon secretion through a glucose concentration-dependent mechanism.GLP-1 can also delay stomach emptying and suppress appetite to help lose weight.This review summarizes clinical evidence of the semaglutide effect on T2D and obesity and establishes expectations on future clinical trials for obesity treatment. | Yalin Liu Xianghang Luo | 2022 | Frontiers of Medicine2022，16，1： | 2 |
| 12 | Study on Wave-influenced resistance to erosion of silty soil in Huanghe (Yellow) River Delta显示文摘Along with the reduction of sediment yield of the Huanghe(Yellow) River,the erosion of the Huanghe River Delta aggravates,which has becomes an important factor that threatens the coastal protection structures.Starting from the study of the erosion resistibility of the sediment,this paper explores the internal mechanism of erosion phenomenon.This paper takes Diaokou as the study area and takes soils as samples which are mixed with clay into reconstructed samples whose ratio of clay content are 5%,10%,15%,20% respectively,then dynamic tri-axial apparatus is applied to simulate wave loads of different intensity;then the resistibility of soil to erosion is determined via concentrated flow test and the structural property is determined via the disintegration test.Finally,the resistibility to erosion and the structural property of the non-compressed soil samples are compared with the compressed data.The results indicates that liquefaction failure exerts significant influence on the resistibility to erosion and the structural property of the silty soil in the Huanghe River Delta.Therefore,in the future erosion studies,the liquefaction phenomenon shall be fully considered. | QIN Hao CHEN Fang LIU Yalin | 2010 | Acta Oceanologica Sinica2010，29，2： | 2 |
| 13 | Positioning taxonomic research for the future显示文摘Why do taxonomists matter? The work of taxonomists is often understated if not completely misunderstood. Without taxonomists, organisms cannot be accurately identified, neither can these organisms be given universally accepted names, and reliably positioned in the phylogenetic tree of life. Thanks to the work of taxonomists over the last 269 years since Carl Linnaeus established the binomial system, we can now measure the health and wealth of our biodiversity in a refined, science-based inventory prescribed by stringent nomenclatural rules. | Deyuan Hong Wenying Zhuang Min Zhu Keping Ma Xiaoquan Wang Dawei Huang Yalin Zhang Guodong Ren Wenjun Bu Wanzhi Cai Dong Ren Ding Yang Aiping Liang Fengyan Bai Runzhi Zhang Fumin Lei Shuqiang Li Hongzhi Kong Lei Cai Yucheng Dai Chaodong Zhu Qisen Yang Jun Chen Zhongli Sha Jianping Jiang Jing Che Donghui Wu Jiatang Li Qiang Wang Xinli Wei Ming Bai Xingyue Liu Xuexin Chen Gexia Qiao | 2022 | Zoological Systematics2022，47，3： | 2 |
| 14 | Sol–gel preparation and enhanced photocatalytic performance of Cu-doped ZnO nanoparticles显示文摘 | Min Fu Yalin Li Siwei wu Peng Lu Jing Liu Fan Dong | 2011 | Applied Surface Science2011，，4： | 1 |
| 15 | A friction contact stiffness model of fractal geometry in forced response analysis of a shrouded blade显示文摘 | LIU Yalin SHANGGUAN Bo XU Zili | 2012 | Nonlinear Dynamics2012，70，3： | 1 |
| 16 | Enhancing near infrared solar cell response using upconverting transparent eeramie显示文摘 | M Liu Yalin Lu Z B Xie G M Chow | 2011 | Solar Energy Materials & Solar Cells2011，95，： | 1 |
| 17 | The effect of classroom wall color on learning performance: A virtual reality experiment显示文摘The wall color has the certain impact on the learning performance of college students in the classroom.To find the suitable wall color to improve the learning performance,this study used the virtual reality(VR)technology to build five virtual classrooms with yellow,red,white,blue,and green walls,while the subjective evaluation and objective physiological indicators of college students were collected.The subjective survey showed the cold-colored walls such as blue and green had the highest levels of relaxation and pleasure,while the warm-colored walls such as yellow and red had the better attention and learning performance.And the white-walled classroom had the lowest subjective evaluation and the worst learning performance,but the white wall was widely used in the present class room.Physiological test results showed the yellow wall had the higher HRV-nLF/nHF and low-β&high-βfrequencies in the FP2 channel in the frontal,but the white wall had the lowest scores.Moreover,the correlation analysis had confirmed electroencephalography(EEG)and electrocardiogram(ECG)indicators could be employed to evaluate the learning performance.These findings provide an effective reference for the spatial design of university classrooms and a basis for the study of physiological indicators. | Chao Liu Yalin Zhang Limei Sun Weijun Gao Qiuyun Zang Jiaxin Li | 2022 | Building Simulation2022，15，12： | 1 |
| 18 | A unified control strategy for three-phase inverter in distributed generation 显示文摘 | Zeng Liu Jinjun Liu Yalin Zhao | 2014 | IEEE Transactions on Power Electronics2014，29，3： | 1 |
| 19 | Endoscopic management for pancreatic injuries due to blunt abdominal trauma decreases failure of nonoperative management and incidence of pancreatic-related complications显示文摘 | Yalin Kong Hongyi Zhang Xiaojun He Chengli Liu Longsong Piao Gang Zhao Yuying Zhen | 2014 | Injury2014，，： | 1 |
| 20 | Cenozoic Vertical-Axis Rotations of the Hoh Xil Basin, Central–Northern Tibet显示文摘Understanding the Cenozoic vertical-axis rotation in the Tibetan Plateau is crucial for continental dynamic evolution. Paleomagnetic and rock magnetic investigations were carried out for the Oligocene and Miocene continental rocks of the Hoh Xil basin in order to better understand the tectonic rotations of central Tibet. The study area was located in the Tongtianhe area located in the southern part of the Hoh Xil basin and northern margin of the Tanggula thrust system in central-northern Tibet. A total of 160 independently oriented paleomagnetic samples were drilled from the Tongtianhe section for this study. The magnetic properties of magnetite and hematite have been recognized by measurements of magnetic susceptibility vs. temperature curves and unblocking temperatures. The mean directions of the Oligocene Yaxicuo Group in stratigraphic coordinates(Declination/Inclination = 354.9°/29.3°, k = 33.0, α_(95) = 13.5°, N =5 Sites) and of the Miocene Wudaoliang Group in stratigraphic coordinates(Declination/Inclination = 3.6°/36.4°, k = 161.0, α_(95) = 9.7°, N =3 Sites) pass reversal tests, indicating the primary nature of the characteristic magnetizations. Our results suggested that the sampled areas in the Tuotuohe depression of the Hoh Xil basin have undergone no paleomagnetically detectable rotations under single thrusting from the Tanggula thrust system. Our findings, together with constraints from other tectonic characteristics reported by previous paleomagnetic studies, suggest tectonic rotations in the Cuoredejia and Wudaoliang depressions of the Hoh Xil basin were affected by strike-slip faulting of the Fenghuo Shan-Nangqian thrust systems. A closer examination of geological data and different vertical-axis rotation magnitudes suggest the tectonic history of the Hoh Xil basin may be controlled by thrust and strike-slip faulting since the Eocene. | RAN Bo ZHAO Xixi LIU Zhifei WANG Chengshan ZHU Lidong JIN Wei LI Yalin | 2016 | Acta Geologica Sinica(English Edition)2016，90，3： | 1 |
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