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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017，27，12： | 70 |
| 2 | Epidemiological characteristics and disease burden of infectious mononucleosis in hospitalized children in China:A nationwide retrospective study显示文摘Epstein-Barr virus(EBV)is very common,with the infection rate in adults over 90%worldwide.Infectious mononucleosis(IM)is caused by primary infection with EBV.Most IM patients are generally considered to have a favorable prognosis,but a few patients will also develop complications.Children with severe symptoms will require hospitalization.However,the disease burden of children hospitalized with IM in China has been rarely described.In this study,we included the Face sheets of discharge medical records from 27 member children's hospitals of Futang Research Center of Pediatric Development from Jan 1st,2016 to Dec 31st,2020,and medical information such as gender,age,region,time of admission,length of stay and expenditure were extracted.There were 24,120 IM cases,which accounted for 0.42%(24,120/5,693,262)of all hospitalized cases during this period.The ratio of male to female was 1.48:1.Hospitalization for IM in the 4-6 years age group was the highest among inpatients of all age groups.Case numbers increased year by year between 2016 and 2020,and the monthly hospitalization was generally high from Jul to Sep but reduced from Jan to Feb per year.Bronchitis/pneumonia and hepatic dysfunction were two common complications in hospitalized IM patients.The median length of stay was 8 days,and the median cost of hospitalization was 970.59 US dollars.This study will help understand the epidemiological characteristics and disease burden of hospitalized children with IM in China. | Mengjia Liu Xinyu Wang Linlin Zhang Guoshuang Feng Yueping Zeng Ran Wang Zhengde Xie | 2022 | Virologica Sinica2022，37，5： | 10 |
| 3 | 小鼠骨骼肌挫伤后基因表达的时间进程(英文)显示文摘Background:Though the mechanisms of skeletal muscle regeneration are deeply understood,those involved in muscle contusion,one of the most common muscle injuries in sports medicine clinics,are not.The objective of this study is to explore the mechanisms involved in muscle regeneration after contusion injury.Methods:In this study,a total of 72 mice were used.Eight of them were randomly chosen for the control group,while the rest were subjected to muscle contusion.Subsequently,their gastrocnemius muscles were harvested at different time points.The changes in muscle morphology were assessed by hematoxylin and eosin(HE) stain.In addition,the gene expression was analyzed by real-time polymerase chain reaction.Results:The data showed that the expression of many genes,i.e.,specific markers of immune cells and satellite cells,regulatory factors for muscle regeneration,cytokines,and chemokines,increased in the early stages of recovery,especially in the first 3 days.Furthermore,there were strict rules in the expression of these genes.However,almost all the genes returned to normal at 14 days post-injury.Conclusion:The sequence of immune cells invaded after muscle contusion was neutrophils,M1 macrophages and M2 macrophages.Some CC(CCL2,CCL3,and CCL4) and CXC(CXCL10) chemokines may be involved in the chemotaxis of these immune cells.HGF may be the primary factor to activate the satellite cells after muscle contusion.Moreover,2 weeks are needed to recover when acute contusion happens as used in this study. | Weihua Xiao Yu Liu Beibei Luo Linlin Zhao Xiaoguang Liu Zhigang Zeng Peijie Chen | 2016 | Journal of Sport and Health Science2016，5，1： | 8 |
| 4 | Resilience-based retrofitting of existing urban RC-frame buildings using seismic isolation显示文摘The improvement of the seismic resilience of existing reinforced-concrete(RC) frame buildings, which is essential for the seismic resilience of a city, has become a critical issue. Although seismic isolation is an effective method for improving the resilient performance of such buildings, target-oriented quantitative improvements of the resilient performance of these buildings have been reported rarely. To address this gap, the seismic resilience of two existing RC frame buildings located in a high seismic intensity region of China were assessed based on the Chinese Standard for Seismic Resilience Assessment of Buildings. The critical engineering demand parameters(EDPs) affecting the seismic resilience of such buildings were identified. Subsequently, the seismic resilience of buildings retrofitted with different isolation schemes(i.e., yield ratios) were evaluated and compared, with emphasis on the relationships among yield ratios, EDPs, and levels of seismic resilience. Accordingly, to achieve the highest level of seismic resilience with respect to the Chinese standard, a yield ratio of 3% was recommended and successfully applied to the target-oriented design for the seismic-resilience improvement of an existing RC frame building. The research outcome can provide an important reference for the resilience-based retrofitting of existing RC frame buildings using seismic isolation in urban cities. | Yang Cantian Xie Linlin Li Aiqun Zeng Demin Jia Junbo Chen Xi Chen Min | 2020 | Earthquake Engineering and Engineering Vibration2020，19，4： | 7 |
| 5 | A Study on Planning Strategies for Urban Housing Block Development显示文摘As a city is the carrier of human society and housing is an important part of a citizen's life and survival, the citizens' choice of their housing mode will inf luence the material and spiritual life of the individuals, families, and society. In view of the diversification of values and investments, people are eager for a harmonious relationship between the community and the city. As a kind of compact and efficient housing mode, the housing block highlights the organic link of the community within the city in an open and shared living environment. This paper reviews the development of housing blocks in various countries and summarizes the characteristics of housing blocks through a comparison with traditional gated residential quarters and urban blocks. It then analyzes the current diffi culties of housing block development in China from aspects such as the planning concept, planning system, management mode, and development mode and accordingly proposes planning principles and strategies in hope of providing theoretical supports for the development and construction of housing blocks in China. | Zeng Wei Wang Hua You Juanjuan Wang Linlin Li Caige(译) | 2016 | China City Planning Review2016，25，4： | 3 |
| 6 | SOD1^(G93A) Induces a Unique PSAP-Dependent Mitochondrial Apoptosis Pathway via Bax-Bak Interaction显示文摘Amyotrophic lateral syndrome(ALS)is a progressive degenerative disorder characterized by motor neuron death and axon degeneration.Mitochondrial dysfunction plays a key role in the pathogenesis of ALS,the mechanism of which remains poorly understood.The B-cell lymphoma-2(Bcl-2)family of proteins that control and mediate mitochondrial function and apoptosis,including the pro-apoptotic members Bcl2-Associated X(Bax),are involved in ALS development.The death receptor 6(DR6)regulates motor neuron death in ALS,and DR6 antibodies can prevent axon degeneration and motor neuron damage by blocking DR6.Previous studies demonstrated that PSAP localized to mitochondria and was required for DR6-induced apoptosis.In this study,SOD1^(G93A) was transfected into the motor neuron cell line NSC-34 to serve as an ALS cell model in vitro.The data assessed the role of PSAP in SOD1^(G93A)induced apoptosis and demonstrated that the overexpression of SOD1^(G93A),but not wtSOD1,induced PARP cleavage,caspase-3 activation,cytochrome c release,and Bax translocation.PSAP,Bax,and Bak were necessary for SOD1^(G93A)induced apoptosis,as silencing PSAP inhibited SOD1^(G93A)-mediated cell death that was dependent on Bax-Bak interaction. | HAN NIU XIN CHEN XUEQI FU JINGTIAN ZHANG GUODONG LI YUXIANG WANG JIAYUE SONG XUETING MA CHEN HU XUEMIN XU FUQIANG ZHANG LINLIN ZENG | 2021 | BIOCELL2021，45，4： | 2 |
| 7 | Characterization of oogonia stem cells in mice by Fragilis显示文摘Dear Editor,Identification of oogonia stem cells would have great potentials in infertility treatment and fertility preservation.Here we tested whether Fragilis/lfitm3 can identify oogonia stem cells in fetal mouse ovaries and their molecular features,if it can,and whether the oogonia stem cells marked by Fragilis can be found in the postnatal ovaries. | Xiaoyan Sheng Chenglei Tian Linlin Liu Lingling Wang Xiaoying Ye Jie Li Ming Zeng Lin Liu | 2019 | Protein & Cell2019，10，11： | 2 |
| 8 | Source profiles of volatile organic compounds (VOCs) measured in China: Part I显示文摘 | Ying Liu Min Shao Linlin Fu Sihua Lu Limin Zeng Dagang Tang | 2008 | Atmospheric Environment2008，，25： | 2 |
| 9 | Source profiles of volatile organic compounds (VOCs) measured in China: Part I显示文摘 | Ying Liu Min Shao Linlin Fu Sihua Lu Limin Zeng Dagang Tang | 2008 | Atmospheric Environment2008，，25： | 2 |
| 10 | The p38-MAPK Pathway Is Involved in Neuroprotection of Artemisinin against H2O2-induced Apoptosis in PC12 Cells显示文摘 | Liu Linlin Zhiwen Zeng Uma Gaur Fengxia Yan Wenhua Zheng | 2017 | Journal of Pharmacy and Pharmacology2017，5，7： | 1 |
| 11 | Stereotactic Biopsy for Intracranial Space-Occupying Lesions: Clinical Avalysis of 550 cases显示文摘 | Xiu Yu Zonghui Liu Zeng min Tian Shiyue Li Hongyun Huang Bo Xiu Quanjun Zhao Linlin Liu | 2000 | Stereotct Funct Neurosurg2000，75，： | 1 |
| 12 | Generation of developmentally competent oocytes and fertile mice from parthenogenetic embryonic stem cells显示文摘Parthenogenetic embryos,created by activation and diploidization of oocytes,arrest at mid-gestation for defective paternal imprints,which impair placental development.Also,viable offspring has not been obtained without genetic manipulation from parthenogenetic embryonic stem cells(pESCs)derived from parthenogenetic embryos,presumably attributable to their aberrant imprinting.We show that an unlimited number of oocytes can be derived from pESCs and produce healthy offspring.Moreover,normal expression of imprinted genes is found in the germ cells and the mice.pESCs exhibited imprinting consistent with exclusively maternal lineage,and higher X-chromosome activation compared to female ESCs derived from the same mouse genetic background.pESCs differentiated into primordial germ cell-like cells(PGCLCs)and formed oocytes following in vivo transplantation into kidney capsule that produced fertile pups and reconstituted ovarian endocrine function.The transcriptome and methylation of imprinted and X-linked genes in pESC-PGCLCs closely resembled those of in vivo produced PGCs,consistent with efficient reprogramming of methylation and genomic imprinting.These results demonstrate that amplification of germ cells through parthenogenesis faithfully maintains maternal imprinting,offering a promising route for deriving functional oocytes and having potential in rebuilding ovarian endocrine function. | Chenglei Tian Linlin Liu Ming Zeng Xiaoyan Sheng Dai Heng Lingling Wang Xiaoying Ye David L.Keefe Lin Liu | 2021 | Protein & Cell2021，12，12： | 1 |
| 13 | Synaptobrevin-2 facilitates the trafficking and function of atrial SK2 channel显示文摘Dear Editor,Small conductance Ca2+-activated potassium (SK) channels are widely expressed in various tissues and play a unique role in regulating cell function by integrating cytosolic Ca2+ levels and membrane potential (Adelman et al., 2012). Xu et al. first identified SK channels in the heart and found that SK channels, particularly the SK2 channel, are preferentially expressed in human and mouse atrial myocytes but not in ventricular myocytes (Xu et al., 2003). This suggests that the | Tao Li Xuehui Fan Yiyan Yu Linlin Chen Wenjun Huang Yan Yang Jimin Cao Xiaorong Zeng Xiaoqiu Tan | 2018 | Science China(Life Sciences)2018，61，5： | 1 |
| 14 | Characteristics and genesis of clay minerals in the northern margin of the Qaidam Basin显示文摘以便在 Qaidam 盆的北边缘开发适当水库保护措施并且改进它的油和煤气的恢复效率,从从 Qaidam 盆的北边缘的十一件泥土岩石样品的泥土矿物质的特征用X光检查衍射分析被调查,扫描电子显微镜( SEM )和精力光谱分析。主要的烃水库的克莱矿物质作文和分发特征,即从侏罗记和 Paleogene 鈥揘e ogene,被探索。我们分析了影响了这些属性的主要因素。结果证明在北边缘的主要泥土矿物质是绿泥石, kaolinite, illite,绿土和 illite/smectite inter-stratified 矿物质。Illite 是在这个区域的最广泛地散布的泥土矿物质。绿泥石主要在全部晚第三纪并且在 Paleogene 的浅地平线被发现。绿土在浅 Paleogene 鈥揘e ogene 被充实。在侏罗记有大量 kaolinite 和 illite/smectite inter-stratified 矿物质。在这个区域影响泥土矿物质的不同发展的主要因素是父母岩石,古气候和 paleowater 媒介条件的性质,成岩作用转变,构造并且地面条件。 | Wang Linlin Jiang Bo Peng Dehua Yin Chengming Zeng Chunlin | 2011 | Mining Science and Technology2011，21，1： | 1 |
| 15 | Molecular level understanding of CO_(2) capture in ionic liquid/polyimide composite membrane显示文摘Ionic liquid(IL)/polyimide(PI)composite membranes demonstrate promise for use in CO_(2)separation applications.However,few studies have focused on the microscopic mechanism of CO_(2)in these composite systems,which is important information for designing new membranes.In this work,a series of systems of CO_(2)in 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide composited with 4,4-(hexafluoroisopropylidene)diphthalic anhydride(6FDA)-based PI,6FDA-2,3,5,6-tetramethyl-1,4-phenylene-diamine,at different IL concentrations were investigated by all-atom molecular dynamics simulation.The formation of IL regions in PI was found,and the IL regions gradually became continuous channels with increasing IL concentrations.The analysis of the radial distribution functions and hydrogen bond numbers demonstrated that PI had a stronger interaction with cations than anions.However,the hydrogen bonds among PI chains were destroyed by the addition of IL,which was favorable for transporting CO_(2).Furthermore,the self-diffusion coefficient and free energy barrier suggested that the diffusion coefficient of CO_(2)decreased with increasing IL concentrations up to 35 wt-%due to the decrease of the fractional free volume of the composite membrane.However,the CO_(2)selfdiffusion coefficients increased when the IL contents were higher than 35 wt-%,which was attributed to the formation of continuous IL domain that benefitted the transportation of CO_(2). | Linlin You Yandong Guo Yanjing He Feng Huo Shaojuan Zeng Chunshan Li Xiangping Zhang Xiaochun Zhang | 2022 | Frontiers of Chemical Science and Engineering2022，16，2： | 1 |
| 16 | Characteristics and genesis of clay minerals in the northern margin of the Qaidam Basin显示文摘 | Wang Linlin Jiang Bo Peng Dehua Yin Chengming Zeng Chunlin | 2011 | Mining Science and Technology (China)2011，，1： | 1 |
| 17 | Source profiles of volatile organic compounds (VOCs) measured in China: Part I显示文摘 | Ying Liu Min Shao Linlin Fu Sihua Lu Limin Zeng Dagang Tang | 2008 | Atmospheric Environment2008，，25： | 1 |
| 18 | The self-assembly and structural regulation of a hydrogen-bonded dimeric building block formed by two N-H…O hydrogen bonds on HOPG显示文摘The self-assembled behavior of an unsymmetric molecule(BCDTDA)with one imidazole group as center and benzoic acid group as functional group is studied,and the regulatory behaviors of coronene(COR)and three bipyridine derivatives(named BP,PEBP-C4 and PEBP-C8)on BCDTDA self-assembly structures are also investigated.Based on highly oriented pyrolytic graphite(HOPG)substrate,scanning tunneling microscopy(STM)is used to observe the variation of assembled behaviors at the solid-liquid interface.Because of the concentration effect,BCDTDA molecules can assemble into grids and Kagomés structures in the form of N–H…O hydrogen bonded dimers.BCDTDA molecules still maintain dimeric structures in the regulation of COR and BP molecules to BCDTDA self-assembly.However,PEBP-C4 and PEBP-C8 destroy the structure of the dimers,and form a variety of co-assembled structures with BCDTDA.Different guest molecules coordinate the host molecules differently,which makes the experiment more meaningful.Combined with density functional theory(DFT)calculation,the discovery of molecular interactions provides a promising strategy for the construction of functional nanostructures and devices. | Peng Lei Lin Ma Siqi Zhang Jianqiao Li Linlin Gan Ke Deng Wubiao Duan Wei Li Qingdao Zeng | 2023 | Chinese Chemical Letters2023，34，8： | 1 |
| 19 | Fast acquisition of L2C CL codes based on combination of hyper codes and averaging correlation显示文摘This paper provides a direct and fast acquisition algorithm of civilian long length(CL) codes in the L2 civil(L2C) signal. The proposed algorithm simultaneously reduces the number of fast Fourier transformation(FFT) correlation through hyper code technique and the amount of points in every FFT correlation by using an averaging correlation method. To validate the proposed acquisition performance, the paper applies this algorithm to the real L2C signal collected by the global positioning system(GPS) L2C intermediate frequency(IF) signal sampler—SIS100L2C. The acquisition results show that the proposed modified algorithm can acquire the code phase accurately with less calculation and its acquisition performance is better than the single hyper code method. | Qingxi Zeng Linlin Tang Pengna Zhang Ling Pei | 2016 | Journal of Systems Engineering and Electronics2016，27，2： | 1 |
| 20 | Correction to:Characterization of oogonia stem cells in mice by Fragilis显示文摘Figure 2.Neo-meiosis and functional test of oocytes developed from Fragilis*cells.(A)Immunofluorescenee of SCP1(red)and SCP3(green,appear as yellowish by merge with SCP1)showing pachytene spread of E12.5 Fragilis*cells obtained from aggregates with fetal E12.5 somatic cells 6 days following transplantation,compared with those of E17.5 ovaries.Right panel,Percentage of synaptonemal complex elements based on count of spread at pachytene(n-22).Scale bar=5 pm.(B)Representative immunofluorescence of MLH1 foci at pachytene stage by co-immunostaining of SCP3(red)and MLH1(green).Right panel,Statistics of MLH1 foci represents 20 spread per each group. | Xiaoyan Sheng Chenglei Tian Linlin Liu Lingling Wang Xiaoying Ye Jie Li Ming Zeng Lin Liu | 2020 | Protein & Cell2020，11，12： | 1 |
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