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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Expression and release of IL-29 by mast cells and modulation of mast cell behavior by IL-29显示文摘 | He, S Zhang, H Chen, H Yang, H Huang, T Chen, Y Lin, J Wang, F Chen, X Li, TL Yang, P | 2010 | 南京医科大学学报(自然科学版)2010，30，11： | 6 |
| 3 | Remifentanil Induces Systemic Arterial Vasodilation which is Not Associated with Alterations in Concentrations of Histamine, Nitric Oxide and Prostacyclin in Patients undergoing Cardiopulmonary Bypass显示文摘 | Lin P T Zhang B.J Wei W Li J Liu J | 2010 | 麻醉与监护论坛2010，17，4： | 3 |
| 4 | 欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。 | 刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F | 2018 | 中华高血压杂志2018，26，4： | 3 |
| 5 | Satellite sensor image classification using cascaded architecture of neural fuzzy network显示文摘 | Lin C T Lee Y C Pu P H | 2000 | IEEE Transactions on Geoscience and Remote Sensing2000，38，2： | 2 |
| 6 | Procedural complexity independent of P2Y12 reaction unit(PRU)values is associated with acute in situ thrombosis in Pipeline flow diversion of cerebral aneurysms显示文摘background Acute in situ thrombosis is an ischaemic phenomenon during Pipeline embolisation device(PED)procedures with potentially high morbidity and mortality.There is controversy regarding the role of platelet function testing with P2Y12 assay as a predictor of intraprocedural thromboembolic events.There is limited knowledge on whether procedural complexity influences these events.Methods Data were collected retrospectively on 742 consecutive PED cases at a single institution.Patients with intraprocedural acute thrombosis were compared with patients without these events.results A cohort of 37 PED cases with acute in situ thrombosis(mean age 53.8 years,mean aneurysm size 8.4 mm)was matched with a cohort of 705 PED cases without intraprocedural thromboembolic events(mean age 56.4 years,mean aneurysm size 6.9 mm).All patients with in situ thrombosis received intra-arterial and/or intravenous abciximab.The two groups were evenly matched in patient demographics,previous treatment/subarachnoid hemorrhage(SAH)and aneurysm location.There was no statistical difference in postprocedural P2Y12 reaction unit(PRU)values between the two groups,with a mean of 156 in the in situ thrombosis group vs 148 in the control group(p=0.5894).Presence of cervical carotid tortuosity,high cavernous internal carotid artery grade,need for multiple PED and vasospasm were not significantly different between the two groups.The in situ thrombosis group had statistically significant longer fluoroscopy time(60.4 vs 38.4 min,p<0.0001),higher radiation exposure(3476 vs 2160 mGy,p<0.0001),higher rates of adjunctive coiling(24.3% vs 8.37%,p=0.0010)and higher utilisation of balloon angioplasty(37.8% vs 12.2%,p<0.0001).Clinically,the in situ thrombosis cohort had higher incidence of major and minor stroke,intracerebral haemorrhage and length of stay.Conclusions Predictors of procedural complexity(higher radiation exposure,longer fluoroscopy time,adjunctive coiling and need for balloon angioplasty)are associated with acute thrombotic events during PED placement,independent of PRU values. | Bowen Jiang Matthew T Bender Erick M Westbroek Jessica K Campos Li-Mei Lin Risheng Xu Rafael J Tamargo Judy Huang Geoffrey P Colby Alexander L Coon | 2018 | Stroke & Vascular Neurology2018，3，3： | 2 |
| 7 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 8 | Study of Self-Crimp Polyester Fibers 显示文摘 | RWEI S P LIN Y T SU Y Y | 2005 | Polymer Engineering and Science2005，45，6： | 1 |
| 9 | Distal Watermarking Based on Neural Networks for Color Images显示文摘 | Yu P T Tsai H H Lin J S | 2001 | Signal Processing2001，81，3： | 1 |
| 10 | Multivariate analysis of soil heavy metal pollution and landscape pattern in Changhua County in Taiwan 显示文摘 | LIN Y P TENG T P CHANG T K | 2002 | Landscape and Urban Planning2002，62，1： | 1 |
| 11 | Thermal stability of sputtered copper films containing dilute insoluble tungsten: thermal annealing study 显示文摘 | Lin C H Chu J P Mahalingam T | 2003 | Mater Res2003，18，6： | 1 |
| 12 | Genetic diversity and biogeography of Cunninghamia konishii ( Cupressaeeae ) , an island species in Taiwan:a comparison with Cunninghamia lanceolata, a mainland species in China显示文摘 | Chung J D Lin T P Tan Y C | 2004 | Molecular Phy- logeneties and Evolution2004，33，： | 1 |
| 13 | Effect of different protein and limiting amino acid levels coupled with a supplement of chromium picolinate on lipid metabolism and carcass characteristics of pigs显示文摘 | Lien T F Wu C P Lin B H | 1998 | Animal Science1998，67，： | 1 |
| 14 | Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres 显示文摘 | Lin J Wu H Tarr P T | 2002 | Nature2002，418，6899： | 1 |
| 15 | Interactive 3-D virtualcolonoscopy system 显示文摘 | LEE T Y LIN P H LIN C H | 1999 | IEEE Trans Inf Technol Biomed1999，3，2： | 1 |
| 16 | Cyclin D1 over expression in esophageal cancer from southern China and its clinical significance 显示文摘 | Huang X P Rong T H Lin P | 2006 | Cancer Lett2006，231，1： | 1 |
| 17 | Intelligent controlled- wind-turbine emulator and induction-generator system using RBFN显示文摘 | Lin F J Teng L T Shieh P H | 2006 | IEEE Proceedings of Electric Power Applications2006，153，4： | 1 |
| 18 | Preparation and properties of nano-silica modified nega- tive acrylate photoresist 显示文摘 | Lee C K Don T M Lai W C Chert C C Lin D J Cheng L P | 2008 | Thin Solid Films2008，516，23： | 1 |
| 19 | Tubular MCM-41-supported transition metal oxide catalysts for ethylbenzene dehydrogenation reaction显示文摘 | Wong S T Lin H P Mou C Y | 2000 | Applied Catalysis A:General2000，198，： | 1 |
| 20 | Molecular detection and differentiation of infectious bursal disease virus 显示文摘 | Wu C C Rubinelli P Lin T L | 2007 | Avian Dis2007，51，： | 1 |
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