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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | The Responsivity of the Bacteriorhodopsin Langmuir-Blodgett Film Intermittent Light显示文摘TheResponsivityoftheBacteriorhodopsinLangmuir-BlodgettFilmIntermittentLight￥GuangYuWANG;JianHuaYANG;ZhiGuangZHANG;ShuHuangLIN... | Wang, GY Yang, JH Zhang, ZG Lin, SH Lu, T Li, BF Jiang, L | 1996 | Chinese Chemical Letters1996，7，12： | 12 |
| 3 | 肝内胆管细胞癌和转移性胰腺导管腺癌的免疫组化鉴别显示文摘在肝脏活检标本中,原发性肝内胆管细胞癌(ICC)和转移性胰腺导管腺癌(PDA)组织学上难以区分,但二者的鉴别具有重要的临床意义。本组实验对41例ICCs和60例PDAs分别进行SLOOP、pVHL、IMP3、肿瘤抑制基因蛋白maspin、MUC5AC及CKl7蛋白的免疫表型评估,以了解这些标志物在两种疾病鉴别诊断中的价值。结果显示:29例(71%)ICCs表达pVHL,PDAs中仅3例(5%)出现pVHL表达。S100P、MUC5AC和CKl7在PDAs中阳性率较高,分别为57例(95%)、40例(67%)和36例(60%),ICCs中S100P、MUC5AC和CK17分别为11例(27%)、5例(12%)及5例(12%)表达。IMP3在ICCs和PDAs中阳性率均为90%。60例(100%)PDA和30例(73%)ICC患者存在maspin的阳性表达。作者对上述标志物表达情况进行归纳后发现,当免疫组化染色结果呈SLOOP-/pVHL+/MUC5AC-/CK17-时提示ICC,呈SLOOP+/pVHL-/MUC5AC+/CK17+和S100P+/pVHL-/MUC5AC-/CK17+时则提示PDA。据此可有效将ICC和PDA鉴别开来。 | Lok T Chen L Lin F 王慧 余英豪 | 2014 | 临床与实验病理学杂志2014，30，10： | 3 |
| 4 | Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers显示文摘 | Shigematsu H Lin L Takahashi T | | 0，，05： | 3 |
| 5 | 欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。 | 刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F | 2018 | 中华高血压杂志2018，26，4： | 3 |
| 6 | 显示文摘 | Lin Y H Tang Z L Zhang Z T | 2003 | J European Ceram Soc2003，23，： | 2 |
| 7 | Procedural complexity independent of P2Y12 reaction unit(PRU)values is associated with acute in situ thrombosis in Pipeline flow diversion of cerebral aneurysms显示文摘background Acute in situ thrombosis is an ischaemic phenomenon during Pipeline embolisation device(PED)procedures with potentially high morbidity and mortality.There is controversy regarding the role of platelet function testing with P2Y12 assay as a predictor of intraprocedural thromboembolic events.There is limited knowledge on whether procedural complexity influences these events.Methods Data were collected retrospectively on 742 consecutive PED cases at a single institution.Patients with intraprocedural acute thrombosis were compared with patients without these events.results A cohort of 37 PED cases with acute in situ thrombosis(mean age 53.8 years,mean aneurysm size 8.4 mm)was matched with a cohort of 705 PED cases without intraprocedural thromboembolic events(mean age 56.4 years,mean aneurysm size 6.9 mm).All patients with in situ thrombosis received intra-arterial and/or intravenous abciximab.The two groups were evenly matched in patient demographics,previous treatment/subarachnoid hemorrhage(SAH)and aneurysm location.There was no statistical difference in postprocedural P2Y12 reaction unit(PRU)values between the two groups,with a mean of 156 in the in situ thrombosis group vs 148 in the control group(p=0.5894).Presence of cervical carotid tortuosity,high cavernous internal carotid artery grade,need for multiple PED and vasospasm were not significantly different between the two groups.The in situ thrombosis group had statistically significant longer fluoroscopy time(60.4 vs 38.4 min,p<0.0001),higher radiation exposure(3476 vs 2160 mGy,p<0.0001),higher rates of adjunctive coiling(24.3% vs 8.37%,p=0.0010)and higher utilisation of balloon angioplasty(37.8% vs 12.2%,p<0.0001).Clinically,the in situ thrombosis cohort had higher incidence of major and minor stroke,intracerebral haemorrhage and length of stay.Conclusions Predictors of procedural complexity(higher radiation exposure,longer fluoroscopy time,adjunctive coiling and need for balloon angioplasty)are associated with acute thrombotic events during PED placement,independent of PRU values. | Bowen Jiang Matthew T Bender Erick M Westbroek Jessica K Campos Li-Mei Lin Risheng Xu Rafael J Tamargo Judy Huang Geoffrey P Colby Alexander L Coon | 2018 | Stroke & Vascular Neurology2018，3，3： | 2 |
| 8 | Characteristics of gas-liquid two-phase flow in small diameter inclined tubes显示文摘 | Cheng T W Lin T L | 2001 | Chem Eng Sci2001，，56： | 2 |
| 9 | Platonin, a cyanine photosensitizing dye, causes attenuation of circulatory shock, hypercoagulable state, and tissue ischemia during heat stroke 显示文摘 | Lee J J Lin M T Wang N L etal | 2005 | Shock2005，24，6： | 1 |
| 10 | Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers显示文摘 | Shigematsu H Lin L Takahashi T | 2005 | J Natl Cancer Inst2005，97，： | 1 |
| 11 | HAESA, an Arabidopsis leucinerich repeat receptor kinase, controls floral organ abscission 显示文摘 | Lin T L Stone J Walker J | 2000 | Genes Dev2000，14，： | 1 |
| 12 | Sensitive and specific detection of strains of Japanese encephalitis virus using a onestep TaqMan RT-PCR technique显示文摘 | Huang J L Lin H T Wang Y M | 2004 | J Med Virol2004，74，4： | 1 |
| 13 | Acetyl danshenxinkun a from Salvia miltiorrhiza 显示文摘 | Lin Y L Liu C Y Chen T H etal | 2003 | J Chin Med2003，14，： | 1 |
| 14 | Autonomous acquisition of seam coor- dinates for arc welding robot based on visual servoing显示文摘 | Zhou L Lin T Chen S B | 2006 | Journal of Intelligent and Robotic Systems: Theory and Applications2006，47，11： | 1 |
| 15 | The characte-rization and mechanism of long afterglow in alkaline earth aluminates phosphors co-doped by Eu2O3 and Dy2O3 显示文摘 | Lin Y H Zhang Z T Tang Z L | 2001 | Materials Chemistry and Physics2001，70，： | 1 |
| 16 | Antioxidant and free radical scavenging effects of baicalein,baicalin and wogonin显示文摘 | SHIEH D E LIU L T LIN C C | 2000 | Anticancer Res2000，20，5： | 1 |
| 17 | Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line显示文摘 | Zhang L Gu J Lin T | 2002 | Gene Ther2002，9，18： | 1 |
| 18 | Bidirectional cytokine interactions in the maternal-fetal relationship:is successful pregnancy a Th2 phenomenon显示文摘 | Wegmann T G Lin H Guilbert L | 1993 | Immunol Today1993，14，： | 1 |
| 19 | Advances in digital video content protection显示文摘 | LIN E T ESKICIOGLU A M LAGENDIJK R L | 2005 | Proceedings of IEEE2005，93，1： | 1 |
| 20 | Bidirectional cytokine interactions in the maternal-fetal relationship:Is successful pregnancy a TH2 phenomenon?显示文摘 | Wegnumn T G Lin H Guilbert L | 1993 | Immunol Today1993，14，7： | 1 |
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