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| 1 | Outcomes of combination MRI-targeted and transperineal template biopsy in restaging low-risk prostate cancer for active surveillance显示文摘Objective:Active surveillance(AS)offers a strategy to reduce overtreatment and now is a widely accepted treatment option for low-risk prostate cancer.An ideal tool for risk-stratification would detect aggressive cancers and exclude such men from taking up AS in the first place.We evaluate if a combination of transperineal template biopsy with magnetic resonance imaging(MRI)-targeted biopsy identifies significant prostate cancer amongst men initially diagnosed with low-risk prostate cancer.Methods:This prospective,single-blinded study included men with low-risk prostate cancer(D’Amico’s Criteria)diagnosed on conventional transrectal ultrasound-guided biopsy.Patients first underwent multiparametric MRI of the prostate6 weeks after initial biopsy.Each suspicious lesion is mapped and assigned a Prostate Imaging Reporting and Data System(PIRADS)score.Template biopsy is first performed with the surgeon blinded to MRI findings followed by MRI-targeted biopsy using a robotic transperineal biopsy platform.Results:The age of the 19 men included is 65.4±4.9 years(mean±SD).Prostate specific antigen(PSA)at diagnosis and at the time of transperineal biopsy were comparable(7.3±1.7 ng/mL and 7.0±1.8 ng/mL,p Z 0.67),so were prostate volumes(34.2±8.9 mL and 32.1±13.4 mL,p Z 0.28).MRI-targeted biopsy had a higher percentage of cancer detection per core compared to template biopsy(11.7%vs.6.5%,p Z 0.02),this was more than 3 times superior for Gleason 7 disease(5.9%vs.1.6%,p<0.01).Four of 18(22.2%)patients with MRI lesions had significant disease with MRI-targeted biopsy alone.Three of 19 patients(15.8%)had significant disease with template biopsy alone.In combination,both techniques upclassified five patients(26.3%),all of whom underwent radical prostatectomy.Whole mount histology confirmed tumour location and grade.All six patients with PIRADS 5 lesions had cancer detected(66.6%significant disease).Conclusion:A combination of MRI-targeted and template biopsy may optimally risk-classify“low-risk”patients diagnosed on initial conventional transrectal ultrasonography(TRUS)prostate biopsy. | Kenneth Chen Kae Jack Tay Yan Mee Law Hakan Aydin Henry Ho Christopher Cheng John Shyi Peng Yuen | 2018 | Asian Journal of Urology2018，5，3： | 2 |
| 2 | Optimum Lymphadenectomy for Esophageal Cancer显示文摘 | Nabil P. Rizk Hemant Ishwaran Thomas W. Rice Long-Qi Chen Paul H. Schipper Kenneth A. Kesler Simon Law Toni E. M. R. Lerut Carolyn E. Reed Jarmo A. Salo Walter J. Scott Wayne L. Hofstetter Thomas J. Watson Mark S. Allen Valerie W. Rusch Eugene H. Blacksto | 2010 | Annals of Surgery2010，，1： | 2 |
| 3 | The effects of leader and follower emotional intelligence on performance and attitude显示文摘 | Chi-Sum Wong Kenneth S Law | 2002 | The Leadership Quarterly2002，，3： | 1 |
| 4 | Impression Management and Faking in Biodata Scores among Chinese Job - Seekers 显示文摘 | Law Kenneth S Mobley etc | 2002 | Asia Pacific Journal of Management2002，，4： | 1 |
| 5 | Nitrogen Fluxes and Retention in Urban Watershed Ecosystems显示文摘 | Peter M. Groffman Neely L. Law Kenneth T. Belt Lawrence E. Band Gary T. Fisher | 2004 | Ecosystems2004，，4： | 1 |
| 6 | Nitrogen fluxes and retention in urban watershed ecosys- tems 显示文摘 | Peter M Groffman Neely L Law Kenneth T Belt | 2004 | Ecosystems2004，7，4： | 1 |
| 7 | High-performance human resource practices,citizenship behavior and organizational performance:a relationship perspective显示文摘 | SUN LI-YUN ARYEE SAMUEL LAW KENNETHS | 2007 | Academy of Management Journal2007，，50： | 1 |
| 8 | High-performance human resource practices, citizenship behavior and organizational pefformance:A Relationship perspective 显示文摘 | Sun Li-yun Aryee Samuel Law Kenneths | 2007 | Academy of Management Journal2007，50，： | 1 |
| 9 | Highperformance Human Resource Practices, Citizenship Behaviour, and Organizational Performance: A Relational Perspective 显示文摘 | Li-Yun Sun Samuel Aryee Kenneth S Law | 2007 | Academy of Management Journal2007，50，3： | 1 |
| 10 | Prognostic Factors Affecting Survival and Recurrence of Patients with pT1 and pT2 Colorectal Cancer显示文摘 | Kenneth S. H. Chok Wai Lun Law | 2007 | World Journal of Surgery2007，，7： | 1 |
| 11 | Instrumental Values of Organizational Citizenship Behavior for Promotion: A Field Quasi- experiment显示文摘 | Chun Hui Lim Simon S K Law Kenneth K S | 2000 | Journal of Applied Psychology2000，85，5： | 1 |
| 12 | Leader-Member Exchange As A Mediator of The Relationship Between Transformational Leadership And Followers' Performance And Organizational Citizenship Behavior显示文摘 | KENNETH S LAW | 2005 | Academy of Management Journal2005，，48： | 1 |
| 13 | A Structural Equation Model of the Effects of Negative Affectivity, Leader-Member Exchange, and Perceived Job Mobility on In-role and Extra-role Performance: A Chinese Case显示文摘 | Chun Hui Kenneth S. Law Zhen Xiong Chen | 1999 | Organizational Behavior and Human Decision Processes1999，，1： | 1 |
| 14 | The effects of leader and follower emotional intelligence on performance and attitude: An exploratory study 显示文摘 | Chi-Sum Wong Kenneth S Law | 2002 | The Leadership Quarterly2002，13，： | 1 |
| 15 | High-Performance human resource practices,citizenship behavior,and organizational performance:A relational perspective显示文摘 | Sun Li-Yun Aryee Samuel Law Kenneth | | 0，，： | 1 |
| 16 | Leader member relationship and burnout: the moderating role of leader integrity显示文摘 | JANE Y JIANG KENNETH S LAW JAMES JM | 2014 | Management and Organization Review2014，10，2： | 1 |
| 17 | The Construct and Criterion Validity of Emotional Intelligence and Its Potential Utility for Management Studies 显示文摘 | Law Kenneth S Wong Chi- Sum | 2004 | Journal of Applied Psychology2004，89，3： | 1 |
| 18 | The organization of societal conflicts by pavement ants Tetramorium caespitum: an agent-based model of amine-mediated decision making显示文摘 | Kevin M. HOOVER Andrew N. BUBAK Isaac J. LAW Jazmine D. W. YAEGER Kenneth J. RENNER John G. SWALLOW Michael J. GREENE | 2016 | Current Zoology2016，62，3： | 1 |
| 19 | Managing localization of human resources in the PRC: a practical model 显示文摘 | Wong Chi-sum Law Kenneth S | 2000 | Journal of World Business2000，34，1： | 1 |
| 20 | Detecting Sorghum Plant and Head Features from Multispectral UAV Imagery显示文摘In plant breeding,unmanned aerial vehicles(UAVs)carrying multispectral cameras have demonstrated increasing utility for high-throughput phenotyping(HTP)to aid the interpretation of genotype and environment effects on morphological,biochemical,and physiological traits.A key constraint remains the reduced resolution and quality extracted from“stitched”mosaics generated from UAV missions across large areas.This can be addressed by generating high-quality reflectance data from a single nadir image per plot.In this study,a pipeline was developed to derive reflectance data from raw multispectral UAV images that preserve the original high spatial and spectral resolutions and to use these for phenotyping applications.Sequential steps involved(i)imagery calibration,(ii)spectral band alignment,(iii)backward calculation,(iv)plot segmentation,and(v)application.Each step was designed and optimised to estimate the number of plants and count sorghum heads within each breeding plot.Using a derived nadir image of each plot,the coefficients of determination were 0.90 and 0.86 for estimates of the number of sorghum plants and heads,respectively.Furthermore,the reflectance information acquired from the different spectral bands showed appreciably high discriminative ability for sorghum head colours(i.e.,red and white).Deployment of this pipeline allowed accurate segmentation of crop organs at the canopy level across many diverse field plots with minimal training needed from machine learning approaches. | Yan Zhao Bangyou Zheng Scott CChapman Kenneth Laws Barbara George-Jaeggli Graeme LHammer David RJordan Andries B.Potgieter | 2021 | Plant Phenomics2021，3，1： | 0 |
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