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| 1 | Encapsulating peritoneal sclerosis显示文摘Encapsulating peritoneal sclerosis(EPS) is a debilitating condition characterized by a fibrocollagenous membrane encasing the small intestine, resulting in recurrent small bowel obstructions. EPS is most commonly associated with long-term peritoneal dialysis, though medications, peritoneal infection, and systemic inflammatory disorders have been implicated. Many cases remain idiopathic. Diagnosis is often delayed given the rarity of the disorder combined with non-specific symptoms and laboratory findings. Although cross-sectional imaging with computed tomography of the abdomen can be suggestive of the disorder, many patients undergo exploratory laparotomy for diagnosis. Mortality approaches 50% one year after diagnosis. Treatment for EPS involves treating the underlying condition or eliminating possible inciting agents(i.e. peritoneal dialysis, medications, infections) and nutritional support, frequently with total parenteral nutrition. EPSspecific treatment depends on the disease stage. In the inflammatory stage, corticosteroids are the treatment of choice, while in the fibrotic stage, tamoxifen may be beneficial. In practice, distinguishing between stages may be difficult and both may be used. Surgical intervention, consisting of peritonectomy and enterolysis, is timeconsuming and high-risk and is reserved for situations in which conservative medical therapy fails in institutions with surgical expertise in this area. Herein we review the available literature of the etiology, pathogenesis, diagnosis, and treatment of this rare, but potentially devastating disease. | Christopher J Danford Steven C Lin Martin P Smith Jacqueline L Wolf | 2018 | World Journal of Gastroenterology2018,24,28: | 13 |
| 2 | Neonatal vitamin A injection promotes cattle muscle growth and increases oxidative muscle fibers显示文摘Background: Vitamin A and its metabolite,retinoic acid(RA),are important regulators of cell differentiation and organ morphogenesis.Its impact on beef cattle muscle growth remains undefined.Method: Angus steer calves were administrated with 0(control) or 150,000 IU vitamin A(retinyl palmitate in glycerol,i.m.) per calf at birth and 1 month of age.At 2 months of age,a biopsy of the Biceps femoris muscle was obtained to analyze the immediate effects of vitamin A injection on myogenic capacity of muscle cells.The resulting steers were harvested at 14 months of age.Results: Vitamin A administration increased cattle growth at 2 months.At 2 months of age,Vitamin A increased PAX7 positive satellite cells and the expression of myogenic marker genes including PAX7,MYF5,MYOD and MYOG.Muscle derived mononuclear cells were further isolated and induced myogenesis in vitro.More myotubes and a higher degree of myogenesis was observed in vitamin A groups.Consistently,vitamin A increased Latissimus dorsi(LD) muscle fiber size at harvest.In addition,vitamin A increased the ratio of oxidative type I and type IIA fibers and reduced the glycolic type IIX fibers.Furthermore,we found that RA,a key bioactive metabolite of vitamin A,activated PPARGC1 A promoter,which explains the upregulated expression of PPARGC1 A in skeletal muscle.Conclusion: Vitamin A administration to neonatal calves enhanced postnatal muscle growth by promoting myogenesis and increasing satellite cell density,accompanied with a shift to oxidative muscle fibers. | Bo Wang Wei Nie Xing Fu Jeanene M de Avila Yannan Ma Mei-Jun Zhu Martin Maquivar Steven M Parish Jan R Busboom Mark L Nelson Min Du | 2019 | Journal of Animal Science and Biotechnology2019,10,1: | 3 |
| 3 | Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy显示文摘 | Sinha Rohit Anthony You Seo-Hee Zhou Jin Siddique Mobin M Bay Boon-Huat Zhu Xuguang Privalsky Martin L Cheng Sheue-Yann Stevens Robert D Summers Scott A Newgard Christopher B Lazar Mitchell A Yen Paul M | 2012 | EN2012,,7: | 2 |
| 4 | VEGF induces Mcl-1 up-regulation and protects multiple my-eloma cells against apoptosis显示文摘 | STEVEN L G KLAUS P MARTINE A | 2004 | Blood2004,104,9: | 1 |
| 5 | Health and economic burden of the projected obesity trends in the USA and the UK显示文摘 | Y Claire Wang Klim McPherson Tim Marsh Steven L Gortmaker Martin Brown | 2011 | 2011 (9793)2011,,9793: | 1 |
| 6 | Vertical and lateral fluidflow related to a large growth fault, South Eugene Island Block330 Field, Offshore Louisiana显示文摘 | Steven L Lorraine E Martin S | 1999 | AAPG Bulletin1999,83,2: | 1 |
| 7 | Scintigraphic Assessment of Regionalized Defects in Myocardial Sympathetic Innervation and Blood Flow Regulation in Diabetic Patients With Autonomic Neuropathy显示文摘 | Martin J Stevens Firat Dayanikli David M Raffel Kevin C Allman Tracy Sandford Eva L Feldman Donald M Wieland James Corbett Marcus Schwaiger | 1998 | Journal of the American College of Cardiology1998,,7: | 1 |
| 8 | Vertical and lateral fluid flow related to a large growth fault, South Eugene island block 330 field,offshore Louisiana显示文摘 | STEVEN L LORRAINE E MARTIN S | 1999 | AAPG Bulletin1999,83,2: | 1 |
| 9 | A Common Network of Functional Areas for Attention and Eye Movements显示文摘 | Maurizio Corbetta Erbil Akbudak Thomas E Conturo Abraham Z Snyder John M Ollinger Heather A Drury Martin R Linenweber Steven E Petersen Marcus E Raichle David C Van Essen Gordon L Shulman | 1998 | Neuron1998,,4: | 1 |
| 10 | Quinolizidine alkaloid synthesis via the intramolecular imi- no Diels-Alder reaction, epi-Lupinine and cryptopleurine 显示文摘 | Martin L Bremmer Nazir A Khatri Steven M Weinreb | 1983 | J Org Chem1983,48,21: | 1 |
| 11 | Vertical and lateral fluid- flow related to a large growth fault, South Eugene Island Block 330 field, Offshore Louisiana 显示文摘 | Steven L Lorraine B E Martin S | 1999 | AAPG Bulletin1999,83,2: | 1 |
| 12 | Style-based inverse kinematics显示文摘 | Grochow Keith L Martin Steven Hertzmann Aaron et al | 2004 | ACM Transactions on Graphics2004,23,3: | 1 |
| 13 | Vertical and lateral fluid flow related to a large growth fault,South Eugene Island Block 330 field,Offshore Louisiana显示文摘 | Steven L Lorraine B E Martin S | 1999 | AAPG Bulletin1999,83,2: | 1 |
| 14 | 查看详情显示文摘 | Steven L Soignet S. R Frankel D. D Martin S.Tallman H.K. Elizabeth C. Richard M.S. Matt K. David A.S. Peter S. Eric L Sievers S.C. Steve D. Ralph E.and Raymond P.W | | 0,,18: | 1 |
| 15 | High-throughput single cell arrays as a novel tool in biopreservation显示文摘 | Kenneth L R Kevin R K Korkut U Steven C H Isaac S K Martin L Y Mehmet T | 2009 | Cryobiology2009,58,3: | 1 |
| 16 | Habitual Physical Activity Behavior of Patients After Primary Total Hip Arthroplasty显示文摘 | Wagenmakers Robert Stevens Martin Zijlstra Wiebren Jacobs Monique L van den Akker-Scheek Inge Groothoff Johan W Bulstra Sjoerd K | 2008 | Physical Therapy2008,,9: | 1 |
| 17 | Natriuretic and antialdosterone actions of chronic oral NEP inhibition during progressive congestive heart failure显示文摘 | MARTIN F L STEVENS T L CATALIOTTI A | 2005 | Kidney Int2005,67,: | 1 |
| 18 | Stylebased inverse kinematics 显示文摘 | Oroehow K Martin Steven L Hertzmann A | 2004 | ACM Transactions on Graphics2004,23,3: | 1 |
| 19 | A meta-analysis of 1-year outcomes of transcatheter versus surgical aortic valve replacement in low-risk patients with severe aortic stenosis显示文摘Background Transcatheter aortic valve replacement(TAVR)for the treatment symptomatic severe aortic stenosis(AS)is indicated in patients with intermediate or higher surgical risk.Latest trials showed TAVR,and surgical aortic valve replacement(SAVR)perform similarly at 1-year for the composite outcomes of mortality,stroke and rehospitalization.We performed a comprehensive meta-analysis to compare individual outcomes at 1-year for TAVR compared to SAVR in low-risk patients.Methods Pub Med,Embase,and Cochrane central were searched for all the randomized controlled trials(RCTs)that reported 1-year comparative outcomes of TAVR and surgical aortic valve replacement(SAVR).Our conclusions are based upon the random-effects model using Der Simonian-Laird estimator.Results Data from 4 trials and 2887 randomized patients showed that TAVR had lower rates of all-cause mortality,cardiovascular mortality,and atrial fibrillation compared to SAVR at 1-year follow-up(P<0.05 for all).Also,TAVR was also associated with a significantly higher risk of permanent pacemaker implantation and moderate-severe paravalvular leak(P<0.05).Conclusions The latest randomised trial data demonstrates that in short-term,TAVR is safe and effective in reducing all-cause mortality or stroke.Longer follow-up of RCTs is needed to determine the durability of clinical benefits in TAVR over SAVR in low-risk patients. | Aaqib H Malik Syed Zaid Hasan Ahmad Joshua Goldberg Tanya Dutta Cenap Undemir Martin Cohen Wilbert S Aronow Steven L Lansman | 2020 | Journal of Geriatric Cardiology2020,17,1: | 0 |