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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | A complete sequence and comparative analysis of a SARS-associated virus(Isolate BJ01)显示文摘The genome sequence of the Severe Acute Respiratory Syndrome (SARS)-associated virus provides essential information for the identification of pathogen(s), exploration of etiology and evolution, interpretation of transmission and pathogenesis, development of diagnostics, prevention by future vaccination, and treatment by developing new drugs. We report the complete genome sequence and comparative analysis of an isolate (BJ01) of the coronavirus that has been recognized as a pathogen for SARS. The genome is 29725 nt in size and has 11 ORFs (Open Reading Frames). It is composed of a stable region encoding an RNA-dependent RNA polymerase (composed of 2 ORFs) and a variable region representing 4 CDSs (coding sequences) for viral structural genes (the S, E, M, N proteins) and 5 PUPs (putative uncharacterized proteins). Its gene order is identical to that of other known coronaviruses. The sequence alignment with all known RNA viruses places this virus as a member in the family of Coronaviridae. Thirty putative substitutions have been identified by comparative analysis of the 5 SARS- associated virus genome sequences in GenBank. Fifteen of them lead to possible amino acid changes (non-synonymous mutations) in the proteins. Three amino acid changes, with predicted alteration of physical and chemical features, have been detected in the S protein that is postulated to beinvolved in the immunoreactions between the virus and its host. Two amino acid changes have been detected in the Mprotein, which could be related to viral envelope formation. Phylogenetic analysis suggests the possibility of non-human origin of the SARS-associated viruses but provides noevidence that they are man-made. Further efforts should focus on identifying the etiology of the SARS-associated virus and ruling out conclusively the existence of otherpossible SARS-related pathogen(s). | QIN E'de ZHU Qingyu YU Man FAN Baochang CHANG Guohui SI Bingyin YANG Bao PENG Wenming JIANG Tao LIU Bohua DENG Yongqiang LIU Hong ZHANG Yu WANG Cui LI Yuquan GAN Yonghua LI Xiaoyu L Fushuang TAN Gang CAO Wuchun, YANG Ruifu Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China WANG Jian, LI Wei, XU Zuyuan, LI Yan, WU Qingfa, LIN Wei, CHEN Weijun, TANG Lin, DENG Yajun, HAN Yujun, LI Changfeng, LEI Meng, LI Guoqing, LI Wenjie, L Hong, SHI Jianping, TONG Zongzhong, ZHANG Feng, LI Songgang, LIU Bin, LIU Siqi, DONG Wei, WANG Jun, Gane K-S Wong, YU Jun & YANG Huanming* Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300 National Center for Genome Information, Beijing 101300, China | 2003 | Chinese Science Bulletin2003，48，10： | 121 |
| 3 | Clinical Features of Adult/Adolescent Atopic Dermatitis and Chinese Criteria for Atopic Dermatitis显示文摘 | Ping Liu Yan Zhao Zhang-Lei Mu Qian-Jin Lu Qian-Jin L U Li Zhang Xu Yao Min Zheng Yi-Wen Tang Xin-Xiano Lu Xiu-Juan xia You-Kun Lin Yu-Zhen Li Cai-Xia Tu Zhi-Rong Yao Jin-Hua Xu Wei Li Wei Lai Hui-Min Yang Hong-Fu Xie Xiu-Ping Han Zhi-Qiang Xie Xiang Nong Zai-Pei Guo Dan-Qi Deng Tong-Xin Shi Jian-Zhong Zhang | 2016 | Chinese Medical Journal2016，，7： | 64 |
| 4 | 中国高血压发病率、知晓率、治疗率和控制率的全国性调查结果显示文摘高血压是全世界心血管疾病的主要危险因素之一。该研究探讨中国高血压的发病率、知晓率、治疗率和控制率。方法:应用多阶段,分层抽样方法抽取中国总人口中年龄≥18岁成人的代表性样品。高血压定义为收缩压≥140和(或)舒张压≥90 mm Hg(1mm Hg=0.133kPa),或自我报告过去2周内使用降压药。结果:在中国,共50 171个受试者完成调查。 | Wang J Zhang L Wang F Liu L Wang H 练桂丽 叶鹏 | 2015 | 中华高血压杂志2015，23，3： | 49 |
| 5 | The crustal structure under Sanjiang and its dynamic implications:Revealed by seismic reflection/refraction profile between Zhefang and Binchuan,Yunnan显示文摘The fault belts in Sanjiang mainly include Jinshajiang-Honghe fault, Lancangjiang fault and Nujiang fault (called Sanjiang faults) in western Yunnan Province, China. By interpreting the wide-angle seismic reflection/refraction profile between Zhefang and Binchuan, which crosses Tengchong and Baoshan blocks in Dianxi (western Yunnan) tectonic zone, we recon- struct the crustal structure with seismic traveltime tomography for crustal P-wave velocity and the seismic scattering image for crustal seismic reflection structure. In this paper, we firstly present the crustal structure images of P-wave velocity and seismic reflection under the wide-angle seismic profile. These results demonstrate that, the crustal velocity structure and seismic reflec- tion structure along the profile can be divided into 3 segments, and there is an obvious difference of crustal structure among the eastern, the western and the middle segment. Generally, crustal P-wave velocities in the Baoshan segment are 0.1―0.2 km/s slower and seismic reflection am- plitudes from Moho discontinuity are stronger than the other 2 segments. In the studied area, crustal thickness is about 40 km, and shows the thickening tendency from west to east along the profile. Additionally, it can be seen that there is one strong-amplitude seismic reflection event as bright points at the depths of 8―10 km, along the segment of 80―115 km of the profile (south- ward of Tengchong); and seismic reflection wave-field from Moho discontinuity varies obviously along the lateral direction. Finally, we make some discussions on the crustal thickening pattern in the Sanjiang fault belt, structural environment of earthquake development and the contact rela- tionship between the Tengchong block, Banshan block and Luxi trough. | ZHANG Zhongjie1, BAI Zhiming1, WANG Chunyong2, TENG Jiwen1, Lü Qingtian3, LI Jiliang1, LIU Yifeng1 & LIU Zhenkuan4 1. Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China 2. Institute of Geophysics, China Seismological Bureau, Beijing 100085, China 3. Institute of Deposition Resource, Chinese Academy of Geosciences, Beijing 100037, China 4. School of Exploration and Information, China University of Geosciences, Beijing 100083, China | 2005 | Science China Earth Sciences2005，48，9： | 39 |
| 6 | Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities显示文摘Aim:To clarify the mechanism of the therapeutic action of icariin on erectlile dysfunction(ED).Methods:PDE5 was isolated from the human platelet and PDE4 form the rat liver tissue using the FPLC system (Pharmacia,Milton Keynes,UK)and the Mono Q column.The inhibitory effects of icariin on PDE5 and PDE4 activities were investigated by the two-step radioisotope procedure with [^3H]-c GMP/[^3H]-cAMP.Papaverine served as the control drug.Results:Icariin and papaverine showed dose-dependent inhibitory effects on PDE5 and PDE4 activities.The IC50 of Icariin and papaverine on PDE5 were 0.432μ mol/L and 0.680μmol/L,respectively and those on PDE4,73.50μmol/L and 3.07μmol/L,respectively.The potencies of selectivity of icariin and papaverine on PDE5(PDE4/PDE5 of IC50)were 167.67 times and 4.54 times,respectively.Conclusion:Icariin is a cGMP-specific PDE5 inhibitor that may be developed into an oral effective agent for the treatment of ED. | ZC Xin EK Kim CS Lin WJ Liu L Tian YM Yuan J Fu | 2003 | Asian Journal of Andrology2003，5，1： | 38 |
| 7 | Abnormal activation of the synuclein-gamma gene in hepatocellular carcinomas by epigenetic alteration.显示文摘 | Zhao W Liu H Liu W Wu Y Chen W Jiang B Zhou Y Xue R Luo C Wang L Jiang JD Liu J | 2006 | 中国生物学文摘2006，20，4： | 31 |
| 8 | Molecular and cellular characterization during chondrogenic differentiation of adipose tissue-derived stromal cells in vitro and cartilage formation in vivo显示文摘 | Lin Y Luo E Chen X Liu L Qiao J Yan Z Li Z Tang W Zheng X Tian W | 2006 | 中国生物学文摘2006，20，5： | 31 |
| 9 | Effect of geniposide, a hypoglycemic glucoside, on hepatic regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin显示文摘 | Shao-yu WU Guang-fa WANG Zhong-qiu LIU in-jun RAO Lin Lü Wei XU Shu-guang WU Jia-jie ZHANG | 2009 | Acta Pharmacologica Sinica2009，30，2： | 33 |
| 10 | Recognition and implication of eclogite in the western Altun Mountains, Xinjiang显示文摘SINCE high-pressure metapelitic rocks have been discovered in the Beiketan area of eastern Al-tun Mountains,a set of eclogite has been recognized in south of Jianggesayi,western Altun.The eclogite,associated with quartz-garnet-clinopyroxenite and metamorphosed retrogradelyto garnet-amphibolite partially,is exposed in the Proterozoic meso- to hypometamorphic rocksand can be traced eastward to northwest of Mangya asbestos deposit,for about 200 | Liu, L Che, ZC Luo, JH Wang, Y Gao, ZJ | 1997 | Chinese Science Bulletin1997，42，11： | 33 |
| 11 | Periodicity of Holocene climatic variations in the Huguangyan Maar Lake显示文摘There exist five primary periods of 2 930, 1 140, 490, 250 and 220 a in the Holocene climatic variations in the Huguangyan Maar Lake, according to the energy-spectrum and filter analyses of high-resolution time sequences (10-15 a) of the sediment dry density. The peak values of the three temperature-decreasing periods with the 2 930 a cycle occur at about 7 300, 4 250 and 1 200 Cal. aBP. There are 7-8 temperature-decreasing periods with the 1 140 a cycle, and the climate fluctuation range is largest in the early Holocene, and reduces gradually in the middle and late Holocene. The millennial-scale climatic change in the Holocene may adjust the global water cycle and the thermohaline circulation intensity through the harmonic tones of the earth’s precession cycle, which in turn influences the global climate change. | LIU Jiaqi LÜ Houyuan JNegendank JMingram LUO Xiangjun WANG Wenyuan CHU Guoqiang | 2000 | Chinese Science Bulletin2000，45，18： | 33 |
| 12 | Invasive mechanism and management strategy of Bemisia tabaci(Gennadius) biotype B:Progress report of 973 Program on invasive alien species in China显示文摘Bemisia tabaci(Gennadius) biotype B,called a 'superbug',is one of the most harmful biotypes of this species complex worldwide.In this report,the invasive mechanism and management of B.tabaci biotype B,based on our 5-year studies,are presented.Six B.tabaci biotypes,B,Q,ZHJ1,ZHJ2,ZHJ3 and FJ1,have been identified in China.Biotype B dominates the other biotypes in many regions of the country.Genetic diversity in biotype B might be induced by host plant,geographical conditions,and/or insecticidal application.The activities of CarE(carboxylesterase) and GSTs(glutathione-S-transferase) in biotype B reared on cucumber and squash were greater than on other host plants,which might have increased its resistance to insecticides.The higher activities of detoxification enzymes in biotype B might be induced by the secondary metabolites in host plants.Higher adaptive ability of biotype B adults to adverse conditions might be linked to the expression of heat shock protein genes.The indigenous B.tabaci biotypes were displaced by the biotype B within 225 d.The asymmetric mating interactions and mutualism between biotype B and begomoviruses via its host plants speed up widespread invasion and displacement of other biotypes.B.tabaci biotype B displaced Trialeurodes vaporariorum(Westwood) after 4-7 generations under glasshouse conditions.Greater adaptive ability of the biotype B to adverse conditions and its rapid population increase might be the reasons of its successful displacement of T.vaporariorum.Greater ability of the biotype B to switch to different host plants may enrich its host plants,which might enable it to better compete with T.vaporariorum.Native predatory natural enemies possess greater ability to suppress B.tabaci under field conditions.The kairomones in the 3rd and 4th instars of biotype B may provide an important stimulus in host searching and location by its parasitoids.The present results provide useful information in explaining the mechanisms of genetic diversity,evolution and molecular eco-adaptation of biotype B.Furthermore,it provides a base for sustainable management of B.tabaci using biological and ecological measures. | WAN FangHao1,ZHANG GuiFen1,LIU ShuSheng2,LUO Chen3,CHU Dong4,ZHANG YouJun4,ZANG LianSheng2,JIU Min2,Lü ZhiChuang1,CUI XuHong1,ZHANG LiPing4,ZHANG Fan3,ZHANG QingWen5,LIU WanXue1,LIANG Pei5,LEI ZhongRen1 & ZHANG YongJun1 1 State Key Laboratory for Biology of Plant Diseases and Insect Pests,Institute of Plant Protection,Chinese Acadeny of Agriculture Sciences,Beijing 100094,China 2 Institute of Applied Entomology,Zhejiang University,Hangzhou 310029,China 3 Institute of Plant and Environment Protection,Beijing Academy of Agricultural and Forestry Sciences,Beijing 100089,China 4 Institute of Vegetables and Flowers,Chinese Acadeny of Agricullare Sciences,Beijing 100081,China 5 Department of Entomology,China Agriculture University,Beijing 100094,China | 2009 | Science China(Life Sciences)2009，52，1： | 30 |
| 13 | Extending the CONSORT Statement to moxibustion显示文摘The STandards for Reporting Interventions in Clinical Trials Of Moxibustion (STRICTOM), in the form of a checklist and descriptions of checklist items, were designed to improve reporting of moxibustion trials, and thereby facilitating their interpretation and replication. The STRICTOM checklist included 7 items and 16 sub-items. These set out reporting guidelines for the moxibustion rationale, details of moxibustion, treatment regimen, other components of treatment, treatment provider background, control and comparator interventions, and precaution measures. In addition, there were descriptions of each item and examples of good reporting. It is intended that the STRICTOM can be used in conjunction with the main CONSORT Statement, extensions for nonpharmacologic treatment and pragmatic trials, and thereby raise the quality of reporting of clinical trials of moxibustion. Further comments will be solicited from the experts of the CONSORT Group, the STRICTA Group, acupuncture and moxibustion societies, and clinical trial authors for optimizing the STRICTOM. | Chung-wah Cheng Shu-fei Fu Qing-hui Zhou Tai-xiang Wu Hong-cai Shang Xu-dong Tang Zhi-shun Liu Jia Liu Zhi-xiu Lin Lixing Lao Ai-ping Lü Bo-li Zhang Bao-yan Liu Zhao-xiang Bian | 2013 | Journal of Integrative Medicine2013，11，1： | 27 |
| 14 | The Chromosome-Level Reference Genome of Tea Tree Unveils Recent Bursts of Nonautonomous LTR Retrotransposons in Driving Genome Size Evolution显示文摘Dear Editor,The tea tree Camellia sinensis,a member of the genus Camellia in the Theaceae family,includes two major cultivated varieties,C.sinensis var.assamica(CSA\Assam type)and C.sinensis var.sinensis(CSS;Chinese type)(Ming and Bartholomew,2007).Due to the high economic importance of the tea tree,considerable efforts have been made to explore genetic basis of the biosynthesis of natural metabolites that determine health benefits and diverse tea flavors(Shi et al.,2011;Li et al.,2011;Li et al.,2015;Xia et aL,2017;Liu et al.,2019). | Qun-Jie Zhang Wei L i Kui Li Hong Nan Cong Shi Yun Zhang Zhang-Yan Dai Yang-Lei Lin Xiao-Lan Yang Yan Tong Dan Zhang Cui Lu Li-Ying Feng Chen-Feng Wang Xiao-Xin Liu Jian-An Huang Wen-Kai Jiang Xing-Hua Wang Xing-Cai Zhang Evan E.Eichler Zhong-Hua Liu and Li-Zhi Gao | 2020 | Molecular Plant2020，13，7： | 27 |
| 15 | Comparison of parathyroid hormone (1-34) and elcatonin in postmenopausal women with osteoporosis: an 18-month randomized, multicenter controlled trial in China显示文摘 | LI Ying XUAN Miao WANG Bo YANG Jun ZHANG Hong ZHANG Xiu-zhen GUO Xiao-hui Lü Xiao-feng XUE Qing-yun YANG Gang-yi JI Qiu-he LIU Zhi-min LI Cheng-jiang WU Tian-feng SHENG Zheng-yan LI Peng-qiu TONG Jiu-cui | 2013 | Chinese Medical Journal2013，，3： | 24 |
| 16 | The global image of the Moon obtained by the Chang'E-1:Data processing and lunar cartography显示文摘The global lunar image of the first phase of Chinese Lunar Exploration Program is the first image that covered all over the surface of the Moon. It will serve as a critical foundation for succeeding exploration and scientific research. In this paper, the acquisition, characteristics, and data quality of Chang'E-1 CCD image data are described in detail. Also described are the methodology and procedure of data processing. According to rule of planetary cartography, the image data have been processed, geometrically corrected, and then mosaicked and merged in a scale of 1:2.5 million. The results of data processing and charting show that the image data of Chang'E-1 CCD and their geometric precision meet the demand of charting a map in the scale of 1:2.5 million. The relative geometric positioning precision of the global image is better than 240 m, and the absolute geometric positioning precision is slightly better than that of the ULCN2005 and Clementine lunar basemap (V2.0). The plane positioning precision is approximately 100-1500 m. This global image proves to be the best global image of the Moon so far in terms of space coverage, image quality, and positioning precision. | LI ChunLai1, LIU JianJun1, REN Xin1, MOU LingLi1, ZOU YongLiao1, ZHANG HongBo1, Lü Chang1, LIU JianZhong1, ZUO Wei1, SU Yan1, WEN WeiBin1, BIAN Wei1, ZHAO BaoChang2, YANG JianFeng2, ZOU XiaoDuan1, WANG Min1, XU Chun1, KONG DeQing1, WANG XiaoQian1, WANG Fang1, GENG Liang1, ZHANG ZhouBin1, ZHENG Lei1, ZHU XinYing1, LI JunDuo1 & OUYANG ZiYuan11 National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012, China 2 Xi’an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi’an 710119, China | 2010 | Science China Earth Sciences2010，53，8： | 22 |
| 17 | Metabolic profiling analysis of a D-galactosamine/lipopolysaccharide- induced mouse model of fulminant hepatic failure显示文摘 | Feng, B Wu, SM Lv, S Liu, F Chen, HS Yan, XZ Li, Y Dong, FT Wei, L | 2007 | 中国生物学文摘2007，21，11： | 23 |
| 18 | Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer显示文摘尽管有最近的进展, oncogenic K 地岬驾驶的胰腺的 ductal 腺癌(PDAC ) 在最致命的人的癌症之中留在现代医学。PDAC 的致病对内在的染色体不稳定性和外来的发炎激活部分可归因。然而,在在胰腺的 tumorigenesis 的这二个事件之间的分子的连接充分还没被建立了。这里,我们证明(HMGB1 ) 细胞内部的高活动性组盒子 1 显著地压制 oncogenic 由禁止染色体的 K-Ras-driven 胰腺的 tumorigenesis 调停不稳定性的支持 inflammatory nucleosome 版本。任何一个单身者的有条件的基因脱离或在胰的 HMGB1 的两等位基因在出生使老鼠变为极其敏感到先锋损害的 oncogenic K-Ras-driven 开始,包括胰腺的 intraepithelial 瘤, intraductal 乳突的 mucinous 瘤,和 mucinous 膀胱的瘤。在胰的 HMGB1 的损失与染色体重新整理和 telomere 畸形描绘的氧化 DNA 损坏和 chromosomal 不稳定性被联系。这些导致煽动性的 nucleosome 版本并且宣传 K-Ras-driven 胰腺的 tumorigenesis。细胞外的 nucleosomes 支持 interleukin 6 (IL-6 ) 由渗入 macrophages/neutrophils 的分泌物并且提高在胰腺的损害表明激活的 oncogenic K 地岬。到 IL-6 或 histone H3 或为先进 glycation 的受体的大美人的抵销的抗体结束产品都限制表明激活的 K 地岬,阻止癌症开发和转移 / 侵略,并且延长在 Pdx1-Cre 的动物幸存; K 地岬 G12D/+;Hmgb1/ 鼠标。由 glycyrrhizin 的 HMGB1 损失的药理学抑制在煽动性的条件下面在老鼠限制 oncogenic K-Ras-driven tumorigenesis。减少在 PDAC 病人的 HMGB1 的原子、全部的细胞的表示与差的全面幸存相关,在 PDAC 与预示、治疗学的关联作为新奇肿瘤 suppressor 支持细胞内部的 HMGB1。 | Rui Kang Yangchun Xie Qiuhong Zhang Wen Hou Qingping Jiang Shan Zhu Jinbao Liu Dexing Zeng Haichao Wang David L Bartlet Timothy R Billiar Herbert J Zeh III Michael T Lotze Daolin Tang | 2017 | Cell Research2017，27，7： | 22 |
| 19 | Exosomes from Suxiao Jiuxin pill-treated cardiac mesenchymal stem cells decrease H3K27 demethylase UTX expression in mouse cardiomyocytes in vitro显示文摘Suxiao Jiuxin 药片(SJP ) 是为在中国的急性冠的症候群的处理的繁体中文药,它包含二个主要部件, tetramethylpyrazine (TMP ) 和龙脑(BOR ) 。因此远然而,在心脏的微型环境上位于 SJP 的有益的效果下面的分子的机制是未知的。心脏的间充质的干细胞(C-MSCs ) 通过 microvesicles (exosomes ) 的版本与 cardiomyocytes (厘米) 交流恢复心脏的动态平衡并且得到修理,部分地通过 epigenetic 规章的机制。在这研究,我们检验了 SJP 处理是否改变了 C-MSC-derived exosomes (SJP-Exos ) 引起 epigenetic 在接受者厘米的色彩的改变。从老鼠心孤立的 C-MSC 是有 SJP (SJP-Exos ) 的 pretreated, TMP (TMP-Exos ) 或 BOR (BOR-Exos ) 。然后, HL-1 房间,一根鼠标 cardiomyocyte 线,从控制与 exosomes 被对待 C-MSCs (Ctrl-Exos ) , SJP-Exos, TMP-Exos 或 BOR-Exos。有 SJP-Exos 的处理显著地增加了 histone 的蛋白质层次 3 离氨酸 27 trimethylation (H3K27me3 ) ,为心脏的 transcriptional 抑制的一个关键 epigenetic 染色质标记,在 HL-1 房间。为了推进,探索 SJP-Exo-mediated H3K27me3 upregulation 的机制,我们在对待 exosome 的 HL-1 房间估计了关键 histone methylases (EZH1, EZH2 和 EED ) 和 demethylases (JMJD3 和 UTX ) 的 mRNA 表示层次。有 SJP-Exo 的处理有选择地在接受者 HL-1 房间压制了 UTX 表示。而且, PCNA,房间复制的一个内长的标记,比在 Ctrl-Exo-treated HL-1 房间在 SJP-Exo-treated HL-1 房间是显著地更高的。这些结果证明 SJP-Exos 增加 cardiomyocyte 增长并且证明 SJP 能调制 C-MSC-derived exosomes 引起 epigenetic 染色质在接受者 cardiomyocytes 改变;因而, SJP-Exos 可能被用来支持 cardiomyocyte 增长。 | Xiao-fen RUAN Yongdun LI Cheng-wei JU Yan SHEN Wei LEI Can CHEN Yang LI Hong YU Yu-tao LIU II-man KIM Xiao-long WANG Neal L WEINTRAUB Yaoliang TANG | 2018 | Acta Pharmacologica Sinica2018，39，4： | 23 |
| 20 | Geochemistry,Nd Isotopic Characteristics of Metamorphic Complexes in Northern Hebei:Implications for Crustal Accretion显示文摘北方中国古地台(NCC ) 的北边缘的中间的片断在 Damiao-Changshaoying 区域主要由变形太古代的 Dantazi 建筑群, Paleoproterozoic Hongqiyingzi 复杂 andunmetamorphosed gabbro-anorthosite-meta-alkaline 花岗石,以及变形迟了的 Paleozoicmafic 组成到 granitoid 岩石。~ 2 .49 Ga Dantazi 复杂 comprisesdioritic-trondhjemitic-granodoritic-monzogranitic 片麻岩在角闪岩变形了到 granulitefacies。石油化学的特征表明大多数岩石属于媒介--tohigh钾计算碱的系列,和显示Mg~#不到 40 ,衰退权利的 REE 模式没有到在使primitivemantle正常化的蜘蛛图的显然积极的 Eu 异例,显然否定的 Th , Nb , Ta 和 Ti 异例,到-0.03,和弄空的披风的ε_( Nd )(t) =+0.65 为agesT_( DM ) =2.78-2.71 Ga 建模。在岩石成因论的学习显示岩石从从在一个大陆人边缘背景的再循环的外壳的 mafic 岩石的部分融化从弄空的披风和 granitoid 岩浆在 mafic 岩浆之间混合的 magmatic 被形成。2.44-2.41 Ga Hongqiyingzi 建筑群被变形 mafic-granodioritic-monzogranitic 片麻岩统治,显示到 Dantazi 建筑群的类似的石油化学的特征,对高钾也就是中等计算碱的系列,和 mafic 岩石在 LILE,否定 Th, Nb, Ta, Zr 异例和积极 Panomalies 显示出明显的变化。并且另外的 granitiod 样品也展出否定 Th, Nb, Ta, P 和 Ti 异例。在 Hongqiyingzi 复杂表演的 Allrocks 没有 Eu 的衰退权利的 REE 模式异例。有ε _(Nd ) 的 Themetamorphic mafic 岩石(t)=-1.64 不能是有 granitoids 的一个相同 magmatic 系列有(t)+3.19 珍视到 +1.94 和 2.55-2.52 Ga 的 T_(DM ) 年龄的ε _(Nd ) 。Thesegranitic 岩石从在一个弧形列岛的外壳的 mafic 岩石设置的少年的部分融化从弄空的披风和岩浆从在 mafic 岩浆之间的混血儿发源。 11 妈 LatePaleozoic 变形 mafic 摇的所有 ~3 和相关花岗石的岩石显示出一个中等钾的 calc-alkalinemagmatic 进化系列,由高Mg~#,显然否定的 Th , Nb , Ta 异例和positive 描绘了 Sr 异例,从不到有ε_( Nd )的强烈否定的 Ti 异例和扁平的 REE 模式(t)= +8.42 ,暗示 mafic 岩浆从弄空的披风被导出。另外的花岗石的岩石不管多么被衰退权利的 REE 模式显然描绘没有到 positiveEu 异例,显著地低的ε_( Nd )(t)= -13.37 到-14.04,和T_( DM ) =1.97-1.96 Ga ,表明 granitoid 岩浆从在来自 ~3 的 mafic 岩浆之间的混血儿被导出 11 Madepleted 披风和 granitoid 岩浆从对早 Paleoproterozoic 太古代古老的外壳的再循环。象上述地质的 andgeochronological 结果一样的地球化学和 Nd 同位素的特征显示 NCC 的北边缘的中间的片断主要经历了四个外壳的生长事件从对太古代晚古生代,它被三个大陆人统治边缘的弧生长( ~2 .49 , ~2 .44 和 311 妈)除了与 post-collisional 扩展有关的 1.76-1.68 Gaepisode ,表明这的外壳的生长分割主要从弧生长和合并被产生到 NCC 大陆块。 | LIU Shuwen TIAN Wei Lü Yongjun LI Qiugen FENG Yonggang K. H. PARK Y. S. SONG | 2006 | Acta Geologica Sinica(English Edition)2006，80，6： | 21 |
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