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| 1 | Factors related to lymph node metastasis and surgical strategy used to treat early gastric carcinoma显示文摘AIM:The prognosis of early gastric carcinoma (EGC) is generally excellent after surgery. The presence or absence of lymph node metastasis in EGC is an important prognostic factor. The survival and recurrence rates of node-negative EGC are much better than those of node-positive EGC. This study examined the factors related to lymph node metastasis in EGC to determine the appropriate treatment for EGC.METHODS: We investigated 748 patients with EGC who underwent surgery between January 1985 and December 1999 at the Division of Gastroenterologic Surgery, Department of Surgery, Chonnam National University Hospital. Several clinicopathologic factors were investigated to analyze their relationship to lymph node metastasis: age, sex, tumor location, tumor size, gross type, histologic type, depth of invasion, extent of lymph node dissection, type of operation,and DNA ploidy.RESULTS:Lymph node metastases were found in 75 patients (10.0%). Univariate analysis showed that male sex, tumor size larger than 2.0cm, submucosal invasion of tumor, histologic differentiation, and DNA ploidy pattern were risk factors for regional lymph node metastasis in EGC patients. However, a multivariate analysis showed that three risk factors were associated with lymph node metastasis:large tumor size, undifferentiated histologic type and submucosal invasion. No statistical relationship was found for age, sex, tumor location, gross type, or DNA ploidy in multivariate analysis. The 5-year survival rate was 94.2% for those without lymph node metastasis and 87.3% for those with lymph node metastasis, and the difference was significant (P<0.05).CONCLUSION: In patients with EGC, the survival rate of patients with positive lymph nodes is significantly worse than that of patients with no lymph node metastasis. Therefore,a standard D2 lymphadenectomy should be performed in patients at high risk of lymph node metastasis: large tumor size, undifferentiated histologic type and submucosal invasion. | Dong Yi Kim Jae Kyoon Joo Seong Yeob Ryu Young Jin Kim Shin Kon Kim | 2004 | World Journal of Gastroenterology2004，10，5： | 68 |
| 2 | Prognostic factors in patients with node-negative gastric carcinoma:A comparison with node-positive gastric carcinoma显示文摘瞄准:识别淋巴的 clinicopathological 特征节点否定的胃的癌,并且另外在淋巴评估结果指示物节点否定的病人。方法:2848 个胃的癌病人,(53.5%) 1524 是淋巴节点否定。统计分析用艇长模型被执行估计结果指示物。结果:在在节点否定的淋巴和淋巴之间的再发率有有效差量节点积极的病人(14.4% 对 41.0% , P<0.001 ) 。5 年的幸存率在比在淋巴节点积极的淋巴是显著地更低的节点否定的病人(31.1% 对 77.4% , P<0.001 ) 。Univariate 分析表明下列因素影响了 5 年的幸存率:耐心的年龄,肿瘤尺寸,侵略的深度,肿瘤地点,起作用的类型,和在起始的诊断的肿瘤舞台。比例的危险回归建模的艇长表明那种肿瘤尺寸, serosal 侵略,和治愈可能性是独立的,淋巴的统计上重要的、预示的指示物节点否定的胃的癌。结论:淋巴节点否定的病人与相对大的肿瘤和 serosal 侵略让对高治愈可能性,而是病人可归因的有利结果有差的预后。治愈可能性是为淋巴的长期的幸存的最可靠的预言者之一节点否定的胃的癌病人。 | Dong Yi Kim Kyeung Won Seo Jae Kyoon Joo Young Kyu Park Seong Yeob Ryu Hyeong Rok Kim Young Jin Kim Shin Kon Kim | 2006 | World Journal of Gastroenterology2006，12，8： | 20 |
| 3 | Intrahepatic biliary cystadenoma:Is there really an almost exclusively female predominance?显示文摘Biliary cystic tumors,such as cystadenomas and cystadenocarcinomas,are rare cystic tumors of the liver,accounting for less than 5% of all intrahepatic cysts of biliary origin.Biliary cystadenomas have been known to occur predominantly in women (> 85%),and 38%-44% of biliary cystadenocarcinomas have occurred in males.We wrote this letter to comment on a brief article (World J Gasteroenterol 2011 January 21;17(3):361-365) regarding a case of intrahepatic biliary cystic neoplasm treated with surgery.The adenoma-carcinoma sequence is the possible mechanism of carcinogenesis.If the carcinogenesis of biliary cystadenocarcinoma occurs in the adenoma-carcinoma sequence,we believe that the male-to-female ratio of cystadenoma should be higher than the incidence rate that has been reported to date. | Ho Hyun Kim Young Hoe Hur Yang Seok Koh Chol Kyoon Cho Jin Woong Kim | 2011 | World Journal of Gastroenterology2011，17，25： | 12 |
| 4 | Undifferentiated embryonal sarcoma of the liver presenting as a hemorrhagic cystic tumor in an adult显示文摘BACKGROUND:Undifferentiated embryonal sarcoma (UES) of the liver is a rare,highly malignant neoplasm with a poor prognosis occurring almost exclusively in late childhood (6-10 years of age).Only a few cases have been reported in adults accounting for less than 1% of all primary liver neoplasms.METHODS:A 47-year-old woman presented with a palpable mass in the left upper abdomen.Magnetic resonance imaging revealed a 12×10 cm cystic mass with hemorrhage in the left lateral segment of the liver.The initial impression was a hemorrhagic cystic tumor of the liver.The patient underwent a left lateral sectionectomy of the liver.Histopathology and immunohistochemistry helped make a diagnosis of UES.RESULTS:The patient recovered uneventfully and received systemic chemotherapy.Radiologic examination for follow-up revealed a metastatic lesion in the lumbar spine (L5).She was subjected to radiotherapy at the lumbar spine.She survived 48 months.CONCLUSION:Although hepatic cyst as UES of the liver is difficult to diagnose because of its rarity in adults and lack of specific findings,it should be considered in a differential diagnosis. | Ho Hyun Kim Jung Chul Kim Eun Kyu Park Young Hoe Hur Yang Seok Koh Chol Kyoon Cho Hyung Seok Kim Hyun Jong Kim | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，6： | 6 |
| 5 | Reconsideration of the phylogenetic positions of three stichotrichous genera Holosticha,Anteholosticha and Pseudokeronopsis (Spirotrichea:Ciliophora) inferred from complete SSU rRNA gene sequences显示文摘The small subunit rRNA (SSU rRNA) gene for six marine stichotrichs, Pseudokeronopsis carnea, P. flava, Holosticha heterofoissneri, H. diademata, H. bradburyae and Anteholosticha manca, was sequenced and characterized. Using this molecular information, the phylogenetic positions of three related genera, Pseudokeronopsis, Holosticha and Anteholosticha were determined. The results indicate that the family Urostylidae is clearly separated from the family Pseudokeronopsidae. The present phylogenetic analyses unambiguously placed Pseudokeronopsis close to Holosticha, and support the conclusion that these genera should be regarded as the members of the order Urostylidae within the stichotrich clade. Furthermore, the results of this study also support the monophyly of the genus Pseud-okeronopsis, the redefinition of Holosticha s. str. and the placement of Anteholosticha in a clade separate from Holosticha. | Lifang Li Weibo Song Mann Kyoon Shin Alan Warren Khaled A.S. Al-Rasheid Abdulaziz A. Al-Khedhairy Saud Al-Arifi | 2009 | Progress in Natural Science:Materials International2009，19，6： | 3 |
| 6 | Crushed Gold Shell Nanoparticles Labeled with Radioactive Iodine as a Theranostic Nanoplatform for Macrophage-Mediated Photothermal Therapy显示文摘Plasmonic nanostructure-mediated photothermal therapy(PTT) has proven to be a promising approach for cancer treatment,and new approaches for its effective delivery to tumor lesions are currently being developed.This study aimed to assess macrophage-mediated delivery of PTT using radioiodine-124-labeled gold nanoparticles with crushed gold shells(124I-Au@AuCBs) as a theranostic nanoplatform.124I-Au@AuCBs exhibited effective photothermal conversion effects both in vitro and in vivo and were efficiently taken up by macrophages without cytotoxicity.After the administration of 124I-Au@AuCB-labeled macrophages to colon tumors,intensive signals were observed at tumor lesions,and subsequent in vivo PTT with laser irradiation yielded potent antitumor effects.The results indicate the considerable potential of 124I-Au@AuCBs as novel theranostic nanomaterials and the prominent advantages of macrophage-mediated cellular therapies in treating cancer and other diseases. | Sang Bong Lee Jae-Eon Lee Sung Jin Cho Jungwook Chin Sang Kyoon Kim In-Kyu Lee Sang-Woo Lee Jaetae Lee Yong Hyun Jeon | 2019 | Nano-Micro Letters2019，11，2： | 3 |
| 7 | The Effect of Proton Pump Inhibitors on Glycated Hemoglobin Levels in Patients With Type 2 Diabetes Mellitus显示文摘 | Na Han Minkyung Oh Su Min Park You Jeong Kim Eun Ju Lee Tae Kyoon Kim Tae Nyun Kim Min Jeong Kwon Mi-kyung Kim Soon Hee Lee Byoung Doo Rhee Jeong Hyun Park | 2013 | Canadian Journal of Diabetes2013，，： | 1 |
| 8 | SET7/9 methylation of the pluripotency factor LIN28A is a nucleolar localization mechanism that blocks let-7 biogenesis in human ESCs显示文摘 | Seung-Kyoon Kim Hosuk Lee Kyumin Han Sang Cheol Kim Yoonjung Choi Sang-Wook Park Geunu Bak Younghoon Lee Jung Kyoon Choi Tae-Kyung Kim Yong-Mahn Han Daeyoup Lee | 2014 | Cell Stem Cell2014，，： | 1 |
| 9 | Thermal analysis for step and flash imprint lithography during UV curing process显示文摘 | Kyoon K E Grant W C | 2006 | Mi- croelectronic Engineering2006，83，2： | 1 |
| 10 | Antibacte-rial activity of chitosans and chitosan oligom显示文摘 | Hong Kyoon No NaYoungPark | 2002 | International Journal of Food Microbiology2002，74，1： | 1 |
| 11 | A survey of artificial intelligence for cognitive radios显示文摘 | He An Bae Kyung Kyoon | 2010 | IEEE Transactions on Vehicular Technology2010，59，4： | 1 |
| 12 | Effect of coalescence on the grain coarsening during liquid-phase sintering of TaC- TiC - Ni cermets显示文摘 | CHOI Kyoon CHOI Jin-Woo KIM Doh-Yeon | 2000 | Acta Mater2000，48，： | 1 |
| 13 | 显示文摘 | Hong Kyoon No Park Na Young Lee Shin Ho | 2002 | International Journal of Food Microbiology2002，74，12： | 1 |
| 14 | Soluble Polyimide Containing a Photoreactive 2-Styrylpyridine Derivative as the Side Group:Synthesis and Characterization显示文摘 | Kim Woo-Sik Ahn Deuk Kyoon Kim Min-Woo | 2004 | Macromolecular Chemistry and Physics2004，205，14： | 1 |
| 15 | Antibacterial activity of chitosans and chitosan oligomers with different molecular weights 显示文摘 | No Hong Kyoon Park NaYoung Lee Shin Ho | 2002 | International Journal of Food Microbiology2002，74，12： | 1 |
| 16 | Antibacterial activity of chitosans and chitosan oligomers with different molecular weights显示文摘 | Hong Kyoon No Na Young Park Shin Ho Lee | 2002 | International Journal of Food Microbiology2002，74，： | 1 |
| 17 | Antibacterial Activity of Chitosans and Chitosan Oligomers with Different Molecular Weights 显示文摘 | Hong Kyoon No Na Young Park | 2002 | International Journal of Food Microbiology2002，，74： | 1 |
| 18 | The Properties of Reactive Hot Melt Polyurethane Adhesives:Effects of Molecular Weight and Reactive Organoclay显示文摘 | Tae Kyoon Kim Byung Kyu Kim Yong Sung Kim | 2009 | Polymer- Plastics Technology and Engineering2009，48，： | 1 |
| 19 | Effect of plasticizer concentration and solvent types on shelf-life of eggs coated with chitosan显示文摘 | Su Hyun Kim Hong Kyoon No Soon Dong Kim | | 0，，04： | 1 |
| 20 | E-cadherin ex pression in early gastric carcinoma and correlation with lymph node metastasis显示文摘 | Yi Kim D Kyoon Joo J Kyu Park Y | 2007 | J Snrg Oncol2007，96，5： | 1 |
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