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| 1 | Palaeozoic tectonic evolution of the Tianshan belt,NW China显示文摘The Chinese Tianshan belt is a major part of the southern Central Asian Orogenic Belt,extending westward to Kyrgyzstan and Kazakhstan.Its Paleozoic tectonic evolution,crucial for understanding the amalgamation of Central Asia,comprises two stages of subduction-collision.The first collisional stage built the Eo-Tianshan Mountains,before a Visean unconformity,in which all structures are verging north.It implied a southward subduction of the Central Tianshan Ocean beneath the Tarim active margin,that induced the Ordovician-Early Devonian Central Tianshan arc,to the south of which the South Tianshan back-arc basin opened.During the Late Devonian,the closure of this ocean led to a collision between Central Tianshan arc and the Kazakhstan-Yili-North Tianshan Block,and subsequently closure of the South Tianhan back-arc basin,producing two suture zones,namely the Central Tianshan and South Tianshan suture zones where ophiolitic mélanges and HP metamorphic rocks were emplaced northward.The second stage included the Late Devonian-Carboniferous southward subduction of North Tianshan Ocean beneath the Eo-Tianshan active margin,underlined by the Yili-North Tianshan arc,leading to the collision between the Kazakhstan-Yili-NTS plate and an inferred Junggar Block at Late Carboniferous-Early Permian time.The North Tianshan Suture Zone underlines likely the last oceanic closure of Central Asia Orogenic Belt;all the oceanic domains were consumed before the Middle Permian.The amalgamated units were affected by a Permian major wrenching,dextral in the Tianshan.The correlation with the Kazakh and Kyrgyz Tianshan is clarified.The Kyrgyz South Tianshan is equivalent to the whole part of Chinese Tianshan(CTS and STS) located to the south of Narat Fault and Main Tianshan Shear Zone;the so-called Middle Tianshan thins out toward the east.The South Tianshan Suture of Kyrgyzstan correlates with the Central Tianshan Suture of Chinese Tianshan.The evolution of this southern domain remains similar from east(Gangou area) to west until the Talas-Ferghana Fault,which reflects the convergence history between the Kazakhstan and Tarim blocks. | Jacques CHARVET SHU LiangShu Sebastien LAURENT-CHARVET WANG Bo Michel FAURE Dominique CLUZEL CHEN Yan Koen De JONG | 2011 | Science China Earth Sciences2011，54，2： | 57 |
| 2 | 能效建筑规划设计方法显示文摘介绍一种应用灵活、使用方便的能效建筑规划设计方法;该方法可以对单个建筑及群体建筑进行综合能效规划设计, 为建筑师开展建筑可持续建筑发展提供了有力工具。 | 姚润明 Koen Steemers Nick Baker 李百战 | 2004 | 建筑学报2004，，8： | 14 |
| 3 | 政府如何支持公私合营模式发展——20个欧洲国家PPP的政府支持情况评估比较显示文摘本文从制度的视角构建一个政府支持公私合营模式(Public Private Partnership,PPP)程度的指数——PPP政府支持指数(PPP Governmental Support Index,GSI)——以评估政府规定的制度体系对在交通基础设施和其他行业引入和推广PPP具有何种程度的促进或阻碍作用。首先,基于大量文献综述界定PPP政府支持指数的要素,包括关于PPP的政策和政治承诺、法律和监管框架,以及精心设计的PPP支持安排。其次,计算20个欧洲国家的PPP政府支持指数,将其分类并比较各国政府对基础设施领域PPP支持程度的异同。再次,探讨20个欧洲国家的制度指数得分与基础设施领域PPP行为的潜在联系。最后,讨论当前的PPP政府支持指数的潜力、实用性以及方法局限性,并详细阐述如何将该指数用于加强交通或其他领域PPP的比较研究中。 | Koen Verhoest Ole Helby Petersen Walter Scherrer Raden Murwantara Soecipto 张帆 | 2015 | 城市交通2015，13，4： | 13 |
| 4 | 持续性躯体形式疼痛障碍患者压力应对特征的调查与分析显示文摘目的:研究持续性躯体形式疼痛障碍患者的压力应对特征,探索其病理、心理发病机制。方法:根据中国精神障碍分类及诊断标准第3版(Chinese Classifcation and Diagnostic Criteria of Mental Disorders-3,CCMD-3)诊断标准选择53例患者纳入实验组,依据分层抽样原则选择正常对照组53例,分别用防御方式问卷、领悟社会支持量表、多伦多述情障碍量表测量。结果:实验组使用不成熟型防御方式的频率高于对照组,述情障碍高于对照组,成熟型防御方式的使用频率、领悟社会支持能力低于对照组,差异均有统计学意义。结论:持续性躯体形式疼痛障碍患者遇到心理压力时不能及时有效发泄情绪,较多地应用躯体化、抱怨、幻想等不成熟的防御机制,并且不能充分领悟和利用社会支持系统,导致内心冲突加重并进入'情绪恶劣—疼痛加重—应对无效'的恶性循环状态,症状迁延难愈。 | 张瑞星 Koen Sevenants 赵山明 李国荣 | 2013 | 中国疼痛医学杂志2013，19，9： | 11 |
| 5 | 基于主体建模方法在货物联合运输枢纽选址最优化的应用(英文)显示文摘提出一种用于评价公路—铁路联合运输货运枢纽选址方案的整数模型.模型中的四个主体为:货运枢纽经营者、交通运输网络设施规划者、客户、社会公众.介绍了可使全局目标优化的基于主体建模方法(ABM)在货运枢纽选址中的应用.最后,以澳大利亚昆士兰州东南部的货物联合运输枢纽为例,介绍了其原始选址过程、个体目标函数测试及基于主体的模型设计过程. | ACKCHAI Sirikijpanichkul KOEN Hvan Dam LUIS Ferreira ZOFIA Lukszo | 2007 | 交通运输系统工程与信息2007，7，4： | 11 |
| 6 | FDG-PET/CT response evaluation during EGFR-TKI treatment in patients with NSCLC显示文摘Over recent years,[18F]-fluorodeoxyglucose positron emission tomography acquired together with low dose computed tomography(FDG-PET/CT)has proven its role as a staging modality in patients with non-small cell lung cancer(NSCLC).The purpose of this review was to present the evidence to use FDG-PET/CT for response evaluation in patients with NSCLC,treated with epidermal growth factor receptor(EGFR)-tyrosine kinase inhibitors(TKI).All published articles from 1November 2003 to 1 November 2013 reporting on 18FFDG-PET response evaluation during EGFR-TKI treatment in patients with NSCLC were collected.In total 7studies,including data of 210 patients were eligible for analyses.Our report shows that FDG-PET/CT responseduring EGFR-TKI therapy has potential in targeted treatment for NSCLC.FDG-PET/CT response is associated with clinical and radiologic response and with survival.Furthermore FDG-PET/CT response monitoring can be performed as early as 1-2 wk after initiation of EGFR-TKI treatment.Patients with substantial decrease of metabolic activity during EGFR-TKI treatment will probably benefit from continued treatment.If metabolic response does not occur within the first weeks of EGFR-TKI treatment,patients may be spared(further)unnecessary toxicity of ineffective treatment.Refining FDG-PET response criteria may help the clinician to decide on continuation or discontinuation of targeted treatment. | Matthijs H van Gool Tjeerd S Aukema Koen J Hartemink Renato A Valdés Olmos Houke M Klomp Harm van Tinteren | 2014 | World Journal of Radiology2014，6，7： | 8 |
| 7 | Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases显示文摘Proteases, enzymes catalyzing the hydrolysis of peptide bonds, are present at high concentrations in the gastrointestinal tract. Besides their well-known role in the digestive process, they also function as signaling molecules through the activation of protease-activated receptors(PARs). Based on their chemical mechanism for catalysis, proteases can be classified into several classes: serine, cysteine, aspartic, metallo- and threonine proteases represent the mammalian protease families. In particular, the class of serine proteases will play a significant role in this review. In the last decades, proteases have been suggested to play a key role in the pathogenesis of visceral hypersensitivity, which is a major factor contributing to abdominal pain in patients with inflammatory bowel diseases and/or irritable bowel syndrome. So far, only a few preclinical animal studies have investigated the effect of protease inhibitors specifically on visceral sensitivity while their effect on inflammation is described in more detail. In our accompanying review we describe their effect on gastrointestinal permeability. On account of their promising results in the field of visceral hypersensitivity, further research is warranted. The aim of this review is to give an overview on the concept of visceral hypersensitivity as well as on the physiological and pathophysiological functions of proteases herein. | Hannah Ceuleers Hanne Van Spaendonk Nikita Hanning Jelena Heirbaut Anne-Marie Lambeir Jurgen Joossens Koen Augustyns Joris G De Man Ingrid De Meester Benedicte Y De Winter | 2016 | World Journal of Gastroenterology2016，22，47： | 7 |
| 8 | Regulation of intestinal permeability: The role of proteases显示文摘The gastrointestinal barrier is-with approximately 400 m^2-the human body's largest surface separating the external environment from the internal milieu. This barrier serves a dual function: permitting the absorption of nutrients, water and electrolytes on the one hand, while limiting host contact with noxious luminal antigens on the other hand. To maintain this selective barrier, junction protein complexes seal the intercellular space between adjacent epithelial cells and regulate the paracellular transport. Increased intestinal permeability is associated with and suggested as a player in the pathophysiology of various gastrointestinal and extraintestinal diseases such as inflammatory bowel disease, celiac disease and type 1 diabetes. The gastrointestinal tract is exposed to high levels of endogenous and exogenous proteases, both in the lumen and in the mucosa. There is increasing evidence to suggest that a dysregulation of the protease/antiprotease balance in the gut contributes to epithelial damage and increased permeability. Excessive proteolysis leads to direct cleavage of intercellular junction proteins, or to opening of the junction proteins via activation of protease activated receptors. In addition, proteases regulate the activity and availability of cytokines and growth factors, which are also known modulators of intestinal permeability. This review aims at outlining the mechanisms by which proteases alter the intestinal permeability. More knowledge on the role of proteases in mucosal homeostasis and gastrointestinal barrier function will definitely contribute to the identification of new therapeutic targets for permeability-related diseases. | Hanne Van Spaendonk Hannah Ceuleers Leonie Witters Eveline Patteet Jurgen Joossens Koen Augustyns Anne-Marie Lambeir Ingrid De Meester Joris G De Man Benedicte Y De Winter | 2017 | World Journal of Gastroenterology2017，23，12： | 6 |
| 9 | Development of polymer–fullerene solar cells显示文摘Global efforts and synergetic interdisciplinary collaborations on solution-processed bulk-heterojunction polymer solar cells(PSCs or OPVs) made power conversion efficiencies over 10%possible.The rapid progress of the field is credited to the synthesis of a large number of novel polymers with specially tunable optoelectronic properties,a better control over the nano-morphology of photoactive blend layers,the introduction of various effective interfacial layers,new device architectures and a deeper understanding of device physics.We will review the pioneering materials for polymer-fullerene solar cells and trace the progress of concepts driving their development.We discuss the evolution of morphology control,interfacial layers and device structures fully exploring the potential of photoactive materials.In order to guide a further increase in power conversion efficiency of OPV,the current understanding of the process of free charge carrier generation and the origin of the photovoltage is summarized followed by a perspective on how to overcome the limitations for industrializing PSCs. | Fengling Zhang Olle Ingans Yinhua Zhou Koen Vandewal | 2016 | National Science Review2016，3，2： | 4 |
| 10 | The TME Trial After a Median Follow-up of 6 Years: Increased Local Control But No Survival Benefit in Irradiated Patients With Resectable Rectal Carcinoma显示文摘 | Koen C.M.J. Peeters Corrie A.M. Marijnen Iris D. Nagtegaal Elma Klein Kranenbarg Hein Putter Theo Wiggers Harm Rutten Lars Pahlman Bengt Glimelius Jan Willem Leer Cornelis J.H. van de Velde | 2007 | Annals of Surgery2007，，5： | 3 |
| 11 | Sustainable urbanization: energy and environment in the Chongqing Municipality, China显示文摘Chongqing is the largest municipality under the Chinese Central Government (MCG) in terms of administrative area and population and is now the most important economic and cultural center of the upper Yangtze River and Three Gorges area. The Three Gorges Dam project, one of the largest world infrastructure projects, causes a great deal of immigration to Chongqing and results in the rapid urbanization of the city, and it has brought in a great deal of environmental impact, which is a global concerned issue. This paper introduces the city profile of Chongqing municipality and its urbanization impact on energy and environment. The demand and the trend of energy consumption in built environment (building and transport) have been analysed. The living environment of Chongqing residents and the local energy efficient policy have been introduced. Finally the authors discuss the key issues of the sustainable urban development of Chongqing. | 李百战 Koen Steermers | 2005 | Journal of Chongqing University2005，4，4： | 3 |
| 12 | 城市建筑日照分布数字图像分析显示文摘由于城市建筑密度加大造成原有的建筑日照分布改变,该文通过对城市建筑群及新建建筑的参数分析,来确定日照分布改变与建筑设计的关系,并引入了数字图像分析方法,进行建筑日照分析。该方法分析过程简便、清晰,结果表达直观。为建筑师、建筑环境工程师进行建筑规划及建筑环境优化设计中,充分考虑建筑日照分布问题提供了参考依据。 | 罗庆 李百战 姚润明 Koen Steemers | 2006 | 太阳能学报2006，27，12： | 3 |
| 13 | Mechanochemical-Assisted Leaching of Lamp Phosphors: A Green Engineering Approach for Rare-Earth Recovery显示文摘稀土元素(REE)是设计和开发可持续能源应用的重要金属。从富含稀土元素的废物流中回收这些元素对实现独立、可持续的未来能源供应至关重要。本文比较了从绿灯荧光体LaPO_4:Ce^(3+),Tb^(3+)回收稀土元素的两种机制:在湿法冶金酸浸工艺前与溶剂冶金机械化学浸出工艺前的机械活化机制。稀土元素浸出率在机械活化后增加60%,完成机械化学浸出工艺后增加98%。高分辨率透射电子显微镜(HR-TEM)成像揭露了系统元素浸出率增加的原因:浸出与浸出模式的改善可归因于晶体形态从单晶体到多晶体的转变。多晶形材料的雏晶尺寸减小至纳米级,使化学单元出现不规则填充,导致晶体内缺陷颗粒边界的增加,从而增强浸出工艺。发明了一种溶剂冶金法将机械活化与浸出工艺结合成一个步骤,这有利于降低运营成本。其结果是简单、高效的工艺提供了更加绿色的荧光体废物回收替代途经。 | Steff Van Loy Koen Binnemans Tom Van Gerven | 2018 | Engineering2018，4，3： | 3 |
| 14 | Distributed localization in wireless sensor networks: a quantitative comparison显示文摘 | Koen Langendoen Niels Reijers | 2003 | Computer Networks2003，，4： | 3 |
| 15 | The geography of collaborative knowledge production in Europe显示文摘 | Jarno Hoekman Koen Frenken Frank Oort | 2009 | The Annals of Regional Science2009，，3： | 3 |
| 16 | Optimizing the operation of the Qingshitan Reservoir in the Lijiang River for multiple human interests and quasi-natural flow maintenance显示文摘For reservoir operation, maintaining a quasi-natural flow regime can benefit river ecosystems, but may sacrifice human interests. This study took the Qingshitan Reservoir in the Lijiang River as a case, and developed an optimization model to explore a trade-off solution between social-economic interests and nature flow maintenance on a monthly base. The objective function considered irrigation, cruise navigation and water supply aspects. An index of flow alteration degree was proposed to measure the difference between the regulated discharge and the natural flow. The index was then used as an additional constraint in the model besides the conventional constraints on reservoir safety. During model solving, different criteria were applied to the index, representing various degrees of alteration of the natural flow regime in the river. Through the model, a relationship between social-economic interests and flow alteration degree was established. Finally, a trade-off solution of the reservoir operation was defined that led to a favorable social-economic benefit at an acceptable alteration of the natural flow. | Qiuwen Chen Duan Chen Ruiguang Han Ruonan Li Jinfeng Ma Koen Blanckaert | 2012 | Journal of Environmental Sciences2012，24，11： | 2 |
| 17 | Modelling the bed characteristics in fluidised-beds for top-spray coating processes显示文摘A particle sub-model describing the bed characteristics of a bubbling fluidised bed is presented.Atomisation air,applied at high pressures via a nozzle positioned above the bed for spray formation,is incorporated in the model since its presence has a profound influence on the bed characteristics,though the spray itself is not yet considered.A particle sub-model is developed using well-known empirical relations for particle drag force,bubble growth and velocity and particle distribution above the fluidised-bed surface.Simple but effective assumptions and abstractions were made concerning bubble distribution,particle ejection at the bed surface and the behaviour of atomisation air flow upon impacting the surface of a bubbling fluidised bed.The model was shown to be capable of predicting the fluidised bed characteristics in terms of bed heights,voidage distributions and solids volume fractions with good accuracy in less than 5 min of calculation time on a regular desktop PC.It is therefore suitable for incorporation into general process control models aimed at dynamic control for process efficiency and product quality in top-spray fluidised bed coating processes. | Mike Vanderroost Frederik Ronsse Koen Dewettinck Jan G.Pieters | 2012 | Particuology2012，10，6： | 2 |
| 18 | Reduction of bend scour with an air-bubble screen-morphology and flow patterns显示文摘The interplay between streamwise flow,curvature-induced secondary flow,sediment transport and bed morphology leads to the formation of a typical bar-pool bed morphology in open-channel bends.The associated scour at the outer bank and deposition at the inner bank may endanger the outer bank's stability or reduce the navigable width of the channel.Previous preliminary laboratory experiments in a sharply curved flume with a fixed horizontal bed have shown that a bubble screen located near the outer bank can generate an additional secondary flow located between the outer bank and the curvature-induced secondary flow and with a sense of rotation opposite to the latter.This bubble-induced secondary flow redistributes velocities and bed shear stresses.The reported study investigates the implications of a bubble screen on the flow and the morphology in configurations with mobile bed.Velocity measurements show that the bubble-induced secondary flow shifts the curvature-induced secondary flow in inwards direction and reduces its strength.The bubble screen considerably reduces morphological gradients.Maximum bend scour is reduced by about 50%and occurs further away from the outer bank where it does not endanger the bank stability anymore.The location of maximum scour coincides with the junction of the curvature-induced and bubble-induced secondary flows.At this same location,the maximum streamwise velocities and maximum vertical velocities impinging on the bed also occur,which indicates their importance with respect to the formation of bend scour.The bubble screen also substantially reduced deposition at the inner bank.These preliminary experiments show the potential of a bubble screen to influence and modify the bed morphology. | Violaine DUGU Koen BLANCKAERT Qiuwen CHEN Anton J.SCHLEISS | 2013 | International Journal of Sediment Research2013，28，1： | 2 |
| 19 | Ecologically-friendly operation scheme for the Jinping cascaded reservoirs in the Yalongjiang River, China显示文摘在河里保存关键生态系统性质的 Ecologically 友好的水库操作过程目的,当最小化社会经济的兴趣的牺牲时。集中于 Jinping 的这研究作为案例研究串联了水库。一个优化模型被开发在除去的自然隧道节,和年度力量生产探索在目标鱼种(Schizothorax chongi ) 的生态的流动要求(EFR ) 之间的平衡。为隧道的 EFR 被 Tennant 方法和一个鱼产地模型分别地决定。优化模型被使用一个适应真实代码的基因算法解决。相应于生态的流动系列的几种操作情形用优化模型被评估。通过比较,一个最佳的运作的计划,在除去的隧道把相对低的力量生产损失与比较喜欢的生态的流动政体相结合,为串联水库被建议。在推荐计划下面,进在旱季的 Dahewan 河活动范围的分泌物从 36 ~ 50 m ^啜 3 ^/s。这将在要保存的隧道启用至少 50% 目标鱼产地,以 2.5% 仅仅年度力量生产损失的成本。学习证明 EFR 的使用是以一个生态地友好的方法的水库操作的优化的一条有效途径。,为另外的重要的鱼种类和生态系统类似的建模工作,由结果的领域确认补充了,被需要以便固定影响的河生态系统的长期的保存[出版摘要] | Duan CHEN Qiuwen CHEN Ruonan LI Koen BLANCKAERT Desuo CAI | 2014 | Frontiers of Earth Science2014，8，2： | 2 |
| 20 | Comparison of the 6th and 7th Editions of the UICC-AJCC TNM Classification for Esophageal Cancer显示文摘 | Koen Talsma Pieter Hagen Brechtje Grotenhuis Ewout Steyerberg Hugo Tilanus Jan Lanschot Bas Wijnhoven | 2012 | Annals of Surgical Oncology2012，，7： | 2 |
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