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| 1 | Manipulation of a VEGF-Notch signaling circuit drives formation of functional vascular endothelial progenitors from human pluripotent stem cells显示文摘人的 pluripotent 干细胞(hPSC ) 导出 endothelial 系细胞组成有希望的来源因为在这个竞技场的治疗学的 revascularization,而是进步被临床上可伸缩的区别协议和在移植之上与宿主发行量集成的一个功能的容器网络的低效的形成的缺乏妨碍了。在绿的地方,使用一根人的胚胎的干细胞记者房间线荧光灯蛋白质表示被 endothelial 驾驶房间特定的 VE-cadherin (VEC ) 倡导者,我们为 > 屏蔽了;60 bioactive 将支持 endothelial 区别,并且发现 BMP4 和 GSK-3β 的那个政府的小分子;在有 VEGF 的一个早阶段和处理的禁止者 -- 在一个以后的阶段表明小径的槽口的 A 和抑制在六天以内导致了 hPSCs 的有效区别到 endothelial 系。这条顺序的途径产生了 >到 endothelial 房间(EC ) 的 hPSCs 的50%变换,明确地 VEC + CD31 + CD34 + CD14 − KDR 在 endothelial 系房间之中展出了更高的 angiogenic 和 clonogenic 增长潜力的高 endothelial 祖先( EP )。药品的抑制或基因槽口发信号击倒,在有 VEGF 的联合 -- 一个处理,经由 KDR + mesodermal 先锋和对成熟 EC 的 EP 的变换的封锁导致了 EP 的有效形成。当移植了进 immunocompromised 老鼠时,产生 EP 成功地与吻合在 vivo 形成了功能的毛状的容器到主人容器。在我们的协议表明电路的这 VEGF-A-Notch 的操作由 12- 导致导出 hPSC 的 EP 的快速的大规模生产到 20 褶层对当前的方法,它可以与与成熟 EC 相比形成能力的优异容器为再生 vascularization 用作一张吸引人的房间人口。 | Makoto Sahara Emil M Hansson Oliver Wemet Kathy O Lui Daniela Spater Kenneth R Chien | 2014 | Cell Research2014，24，7： | 10 |
| 2 | Usefulness of an abnomal ankle-brachial index to predict presence of coronary artery disease in African-Americans显示文摘 | Kenneth E Atul M Eseroghene O | 2004 | Am J Cardiol2004，93，2： | 1 |
| 3 | In vitro alterations of intestinal bacterial microbiota in fecal samples during storage显示文摘 | Stephan J O Meike M Kenneth N T | 2004 | Diagnostic Microbiology and Infectious Disease2004，50，： | 1 |
| 4 | Infrared spectrum of SOF2显示文摘 | KENNETH O'LOANE J WILSON K M | 1955 | The Jourual of Chemical Physics1955，23，7： | 1 |
| 5 | Coq3orate Soccial Responsibility in Supply Chains of Global Brands:A Boundadaess Responsibility? Clarifications,Exceptions and hnplications显示文摘 | KENNETH M A ONYEKA K O PAUI N | 2008 | Journal of Business Ethics2008，81，1： | 1 |
| 6 | Usefullness of an abnormal ankle-brachial index to predict presence of coronary artery disease in African-Americans显示文摘 | Kenneth E Atul M Eseroghene O | 2004 | Am J Cardiol2004，93，： | 1 |
| 7 | Usefullness of an abnormal ankle-brachial index to predict presence of coronary artery disease in African-Americans显示文摘 | Kenneth E Atul M Eseroghene O | 2004 | Am J Cardiol2004，93，： | 1 |
| 8 | Efficient surface reconstruction from contours based ontwo-dimensional Delaunay triangulation 显示文摘 | WANG De-sheng OUBAY H O KENNETH M K | 2006 | International Journal for Numerical Methods in Engineering2006，65，5： | 1 |
| 9 | The binding of manganese-nucleoside diphosphates to creatine kinase as determined by proton relaxation rate measure- ments显示文摘 | William J O George H R Kenneth H M | 1972 | JBiolChem1972，247，： | 1 |
| 10 | Linkage disequilibrium mapping of Arabidopsis CRY2 flowering time alleles显示文摘 | Kenneth M O Solveig S H John R S | 2004 | Genetics2004，167，： | 1 |
| 11 | Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study显示文摘 | Kenneth J O’Byrne Ulrich Gatzemeier Igor Bondarenko Carlos Barrios Corinna Eschbach Uwe M Martens Yevhen Hotko Cornelius Kortsik Luis Paz-Ares Jose R Pereira Joachim von Pawel Rodryg Ramlau Jae-Kyung Roh Chih-Teng Yu Christopher Stroh Ilhan Celik Armin Sc | 2011 | Lancet Oncology2011，，8： | 1 |
| 12 | A new classification of Cyperaceae (Poales) supported by phylogenomic data显示文摘Cyperaceae(sedges)are the third largest monocot family and are of considerable economic and ecological importance.Sedges represent an ideal model family to study evolutionary biology due to their species richness,global distribution,large discrepancies in lineage diversity,broad range of ecological preferences,and adaptations including multiple origins of C4 photosynthesis and holocentric chromosomes.Goetghebeur′s seminal work on Cyperaceae published in 1998 provided the most recent complete classification at tribal and generic level,based on a morphological study of Cyperaceae inflorescence,spikelet,flower,and embryo characters,plus anatomical and other information.Since then,several family-level molecular phylogenetic studies using Sanger sequence data have been published.Here,more than 20 years after the last comprehensive classification of the family,we present the first family-wide phylogenomic study of Cyperaceae based on targeted sequencing using the Angiosperms353 probe kit sampling 311 accessions.In addition,62 accessions available from GenBank were mined for overlapping reads and included in the phylogenomic analyses.Informed by this backbone phylogeny,a new classification for the family at the tribal,subtribal,and generic levels is proposed.The majority of previously recognized suprageneric groups are supported,and for the first time,we establish support for tribe Cryptangieae as a clade including the genus Koyamaea.We provide a taxonomic treatment including identification keys and diagnoses for the 2 subfamilies,24 tribes,and 10 subtribes,and basic information on the 95 genera.The classification includes five new subtribes in tribe Schoeneae:Anthelepidinae,Caustiinae,Gymnoschoeninae,Lepidospermatinae,and Oreobolinae. | Isabel Larridon Alexandre R.Zuntini Étienne Léveillé-Bourret Russell L.Barrett Julian R.Starr AMuthama Muasya Tamara Villaverde Kenneth Bauters Grace E.Brewer Jeremy J.Bruhl Suzana M.Costa Tammy L.Elliott Niroshini Epitawalage Marcial Escudero Isabel Fairlie Paul Goetghebeur Andrew LHipp Pedro Jiménez-Mejías Izai ABSabino Kikuchi Modesto Luceño JoséIgnacio Márquez-Corro Santiago Martín-Bravo Olivier Maurin Lisa Pokorny Eric HRoalson Ilias Semmouri David A.Simpson Daniel Spalink WWayt Thomas Karen L.Wilson Martin Xanthos Félix Forest William J.Baker | 2021 | Journal of Systematics and Evolution2021，59，4： | 1 |
| 13 | Ches apeake Bay: an unprecedented decline in submerged aquatic vegetation 显示文摘 | Robert J O Kenneth A M | 1983 | Science1983，222，： | 1 |
| 14 | In vitro alterations of intestinal bacterial microbiota in fecal samples during storage 显示文摘 | STEPHAN J O MEIKE M KENNETH N T | 2004 | Diagnostic Microbiology and Infectious Disease2004，50，： | 1 |
| 15 | The application of signal detection theory to weather forecasting behavior显示文摘 | Harvey Lewis O Jr Kenneth R Hammond Cynthia M Lusk | 1992 | Mon Wea Rev1992，120，： | 1 |
| 16 | View: regression of cervical disc herniation observed on magnetic resonance images 显示文摘 | KENNETH B H M D POINT O | 1998 | Spine1998，23，9： | 1 |
| 17 | Usefullness of an abnormal ankle-brachial index to predict presence of coronary artery disease in African-Americans显示文摘 | Kenneth EO Atul M Eseroghene O | 2004 | Am J Cardiol2004，93，： | 1 |
| 18 | Usefullness of an abnormal ankle brachial index to predipresence of coronary artery disease in African-Americans显示文摘 | Kenneth E Atul M Eseroghene O | 2004 | Am J Cardiol2004，93，4： | 1 |
| 19 | Fiber Bragg grating technology funda-mentally and overview 显示文摘 | Kenneth O H Gerald M | 1997 | Journal of Lightwave Technology1997，15，8： | 1 |
| 20 | Deliberating future is- sues : minipublics and salmon genomics 显示文摘 | Kenzie M Kenneth M Kieran D O | 2011 | Journalof Pub- lic Deliberation2011，，1： | 1 |
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