|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Capsule endoscopy of the future: What's on the horizon?显示文摘Capsule endoscopes have evolved from passively moving diagnostic devices to actively moving systems with potential therapeutic capability. In this review,we will discuss the state of the art, define the current shortcomings of capsule endoscopy, and address research areas that aim to overcome said shortcomings.Developments in capsule mobility schemes are emphasized in this text, with magnetic actuation being the most promising endeavor. Research groups are working to integrate sensor data and fuse it with robotic control to outperform today's standard invasive procedures, but in a less intrusive manner. With recent advances in areas such as mobility, drug delivery, and therapeutics, we foresee a translation of interventional capsule technology from the bench-top to the clinical setting within the next 10 years. | Piotr R Slawinski Keith L Obstein Pietro Valdastri | 2015 | World Journal of Gastroenterology2015，21，37： | 8 |
| 2 | Advanced endoscopic technologies for colorectal cancer screening显示文摘Colorectal cancer is the third most common cancer in men and the second most common cancer in women worldwide. Diagnosing colorectal has been increasingly successful due to advances in technology. Flexible endoscopy is considered to be an effective method for early diagnosis and treatment of gastrointestinal cancer, making it a popular choice for screening programs. However, millions of people who may benefit from endoscopic colorectal cancer screening fail to have the procedure performed. Main reasons include psychological barriers due to the indignity of the procedure, fear of procedure related pain, bowel preparation discomfort, and potential need for sedation. Therefore, an urgent need for new technologies addressing these issues clearly exists. In this review, we discuss a set of advanced endoscopic technologies for colorectal cancer screening that are either already available or close to clinical trial. In particular, we focus on visual-inspectiononly advanced flexible colonoscopes, interventional colonoscopes with alternative propulsion mechanisms, wireless capsule colonoscopy, and technologies for intraprocedural bowel cleansing. Many of these devices have the potential to reduce exam related patient discomfort, obviate the need for sedation, increase diagnostic yield, reduce learning curves, improve access to screening, and possibly avert the need for a bowel preparation. | Keith L Obstein Pietro Valdastri | 2013 | World Journal of Gastroenterology2013，19，4： | 4 |
| 3 | Comparison of parametric and nonparametric models for traffic flow forecasting显示文摘 | Brian L Smith Billy M Williams R Keith Oswald | 2002 | Transportation Research Part C2002，，4： | 3 |
| 4 | Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer显示文摘AIM:To assess the feasibility of endoscopic ultrasound(EUS)guided celiac plexus neurolysis(CPN) using a poloxamer. METHODS:In this prospective evaluation,six Yorkshire pigs underwent EUS-guided CPN.Three received an injection of 10 mL of 0.25%Lidocaine plus methylene blue(group 1) and three received an injection of 10 mL of 0.25%Lidocaine plus blue colored poloxamer(PS137-25)(group 2) .Necropsy was performed immediately after the animals were sacrificed.The abdominal and pelvic cavities were examined for the presence of methylene blue and the blue colored poloxamer.RESULTS:EUS-guided CPN was successfully performed in all 6 pigs without immediate complication.Methylene blue was identified throughout the peritoneal and retroperitoneal cavity in group 1.The blue colored poloxamer was found in the retroperitoneal cavity immediately adjacent to the aorta,in the exact location of the celiac plexus in group 2.CONCLUSION:EUS-guided CPN using a reverse phase polymer in a non-survival porcine model was technically feasible.The presence of a poloxamer gel at the site of the celiac plexus at necropsy indicates a precise delivery of the neurolytic agent. | Keith L Obstein Fernanda P Martins Gloria Fernández-Esparrach Christopher C Thompson | 2010 | World Journal of Gastroenterology2010，16，6： | 3 |
| 5 | Treatment of intracranial gliomas with bone marrow- derived dendritic cells pulsed with tumor antigens显示文摘 | Linda M Liau MD Keith L | 1999 | J Neurosurg1999，90，6： | 2 |
| 6 | Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer显示文摘 | Masahito Tachibana Paula Amato Michelle Sparman Nuria Marti Gutierrez Rebecca Tippner-Hedges Hong Ma Eunju Kang Alimujiang Fulati Hyo-Sang Lee Hathaitip Sritanaudomchai Keith Masterson Janine Larson Deborah Eaton Karen Sadler-Fredd David Battaglia David L | 2013 | Cell2013，，6： | 2 |
| 7 | Evaluation and treatment of internal impingement of the shoulder in overhead athletes显示文摘One of the most common pathologic processes seen in overhead throwing athletes is posterior shoulderpain resulting from internal impingement. 'Internal impingement' is a term used to describe a constellation of symptoms which result from the greater tuberosity of the humerus and the articular surface of the rotator cuff abutting the posterosuperior glenoid when the shoulder is in an abducted and externally rotated position. The pathophysiology in symptomatic internal impingement is multifactorial,involving physiologic shoulder remodeling,posterior capsular contracture,and scapular dyskinesis. Throwers with internal impingement may complain of shoulder stiffness or the need for a prolonged warm-up,decline in performance,or posterior shoulder pain. On physical examination,patients will demonstrate limited internal rotation and posterior shoulder pain with a posterior impingement test. Common imaging findings include the classic 'Bennett lesion' on radiographs,as well as articular-sided partial rotator cuff tears and concomitant SLAP lesions. Mainstays of treatment include intense non-operative management focusing on rest and stretching protocols focusing on the posterior capsule. Operative management is variable depending on the exact pathology,but largely consists of rotator cuff debridement. Outcomes of operative treatment have been mixed,therefore intense non-operative treatment should remain the focus of treatment. | Keith T Corpus Christopher L Camp David M Dines David W Altchek Joshua S Dines | 2016 | World Journal of Orthopedics2016，7，12： | 2 |
| 8 | Induction of a high incidence of lung tumors in C57BL/6 mice with multiple ethyl carbamate injections显示文摘 | York E Miller Lori D Dwyer-Nield Robert L Keith Mysan Le Wilbur A Franklin Alvin M Malkinson | 2003 | Cancer Letters2003，，2： | 2 |
| 9 | Lymphoepithelial cysts and cystic lymphangiomas: Underrecognized benign cystic lesions of the pancreas显示文摘AIM: To identify their diagnostic and prognostic clinical characteristics in a large series.METHODS: Retrospective review of clinicopathologic and imaging characteristics of patients diagnosed with lymphoepithelial cysts and cystic lymphangiomas of the pancreas at Massachusetts General Hospital.RESULTS: Twelve patients were identified between 1/1/1997 and 8/1/2007. Their median age was 55.5 years(range 19-78 years), and 6 were females. The le-sion was incidentally discovered in half of the patients.Contrast enhanced computed tomography demonstrat-ed that the cysts had thin walls, without calcifications, pancreatic duct dilation or pancreatic parenchyma inva-sion. Endoscopic ultrasound with fine needle aspiration(EUS/FNA) confirmed the diagnosis of a lymphoepithe-lial cyst in 3 patients, one of whom was spared an op-eration and continues to do well after 6 years. Eleven patients had a resection: 3 pancreaticoduodenecto-mies, 7 distal pancreatectomies, and 1 enucleation. The median size of the cysts was 3 cm(range 2-20 cm). At a median follow-up of 57 mo no recurrences or other pancreas-related conditions occurred.CONCLUSION: Lymphoepithelial cysts and cystic lymphangiomas of the pancreas can be diagnosed with a combination of contrast-enhanced computed tomog-raphy scans and EUS/FNA. If the lesion is asymptom-atic, an operation might be avoided. | Ioannis T Konstantinidis Avinash Kambadakone Onofrio A Catalano Dushyant V Sahani Vikram Deshpe David G Forcione Jennifer A Wargo Carlos Fernandez-del Castillo Keith D Lillemoe Andrew L Warshaw Cristina R Ferrone | 2014 | World Journal of Gastrointestinal Surgery2014，6，7： | 2 |
| 10 | Analytical methods for detection of selected estrogenic compounds in aqueous mixtures 显示文摘 | Snyder S A Keith T L Verbrugge D A | 1999 | Environ Sci Technol1999，33，16： | 2 |
| 11 | Comparison of parametric and nonparametric models for traffic flow forecasting显示文摘 | Smith B L Williams B M Keith Oswald R | 2002 | Transportation Research Part C2002，10，： | 1 |
| 12 | Effects of soil phosphorous availability,temperature and moisture on soil respiration in Eucalyptus pauciflora forest显示文摘 | Keith H Jacobsen L Raison R J | 1997 | Plant and Soil1997，190，1： | 1 |
| 13 | Comparison of parametric and nonparametric models显示文摘 | Brian L Smith Billy M Williams R Keith Oswald | 2002 | Transportation Research Part C2002，，10： | 1 |
| 14 | Analysis of soil wetting and solute transport in subsurface trickle irrigation显示文摘 | Cote Claire M Bristow Keith L Charlesworth pllilip B | 2003 | Irrigation Science2003，22，3： | 1 |
| 15 | New chemical constituents of Planchonia careya 显示文摘 | Peck W K Keith G L | 1977 | Aust J Chem1977，30，： | 1 |
| 16 | Catalytic oxidation of methanol on nanoscale copper oxide and nickel oxide显示文摘 | Gu Zheng Hohn Keith L | 2004 | Ind Eng Chem Res2004，43，： | 1 |
| 17 | Model-Set Adaptation Using a Fuzzy Kalman Filter显示文摘 | Ding Zhen Henry L Keith C | 2001 | Mathematical and Computer Modeling2001，34，： | 1 |
| 18 | Predicting the ther mal conductivity of multiple carbon fillers in polypropylene- based resins 显示文摘 | Gaxiola D L Keith J M Mo Na | 2011 | J Compos Mater2011，45，12： | 1 |
| 19 | Dynamic model- ing of a dual clearance squeeze film damper:Part I test rigand dynamic model with one damper显示文摘 | Moraru L Keith T G Jr Dimofte F | 2003 | Tribology Trans- actions2003，46，2： | 1 |
| 20 | Effects of soil phosphorus availability, temperature and moisture on soil respiration in Eucalyptus pauciflora forest显示文摘 | KEITH H JACOBSEN K L RAISON R J | 1997 | Plant and Soil1997，190，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员