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| 1 | Treatment modalities for hypersplenism in liver transplant recipients with recurrent hepatitis C显示文摘Hepatitis C is the most common indication for orthotopic liver transplantation in the United States. Unfortunately, hepatitis C recurs universally in the transplanted liver and is the major cause of decreased graft and patient survival. The combination therapy of interferon and ribavirin has been shown to be the most effective therapy for recurrent hepatitis C. However, pre-and post-transplant hypersplenism often precludes patients from receiving the antiviral therapy. Splenectomy and partial splenic embolization are the two invasive modalities that can correct the cytopenia associated with hypersplenism. In this report we review the two treatment options, their associated outcomes and complications. | Lena Sibulesky Justin H Nguyen Ricardo Paz-Fumagalli C Burcin Taner Rolland C Dickson | 2009 | World Journal of Gastroenterology2009，15，40： | 5 |
| 2 | Preventing infective complications in inflammatory bowel disease显示文摘Over the past decade there has been a dramatic change in the treatment of patients with Crohn’s disease and ulcerative colitis,which comprise the inflammatory bowel diseases(IBD).This is due to the increasing use of immunosuppressives and in particular the biological agents,which are being used earlier in the course of disease,and for longer durations,as these therapies result in better clinical outcomes for patients.This,however,has the potential to increase the risk of opportunistic and serious infections in these patients,most of which are preventable.Much like the risk for potential malignancy resulting from the use of these therapies long-term,a balance needs to be struck between medication use to control the disease with minimization of the risk of an opportunistic infection.This outcome is achieved by the physician’s tailored use of justified therapies,and the patients’education and actions to minimize infection risk.The purpose of this review is to explore the evidence and guidelines available to all physicians managing patients with IBD using immunomodulating agents and to aid in the prevention of opportunistic infections. | Justine Mill Ian C Lawrance | 2014 | World Journal of Gastroenterology2014，20，29： | 4 |
| 3 | Histopathological characteristics and causes of kidney graft failure in the current era of immunosuppression显示文摘BACKGROUND The histopathological findings on the failing kidney allograft in the modern era is not well studied. In this study, we present our experience working with kidney transplant recipients with graft failure within one year of the biopsy.AIM To report the histopathological characteristics of failed kidney allografts in the current era of immunosuppression based on the time after transplant, cause of the end-stage renal disease and induction immunosuppressive medications.METHODS In a single-center observational study, we characterized the histopathological findings of allograft biopsies in kidney transplant recipients with graft failure within one year after the biopsy.RESULTS We identified 329 patients with graft failure that met the selection criteria between January 1, 2006 and December 31, 2016. The three most common biopsy findings were interstitial fibrosis and tubular atrophy(IFTA, 53%), acute rejection (AR, 43%) and transplant glomerulopathy(TG, 33%). Similarly, the three most common causes of graft failure based on the primary diagnosis were AR(40%),TG(17%), and IFTA(13%). Most grafts failed within two years of post-transplant(36%). Subsequently, approximately 10%-15% of grafts failed every two years: >2-4 years(16%), > 4-6 years(13%), > 6-8 years(11%), > 8-10 years(9%) and > 10 years(16%). AR was the most common cause of graft failure in the first six years(48%), whereas TG was the most prevalent cause of graft failure after 6 years(32%) of transplant.CONCLUSION In the current era of immunosuppression, AR is still the most common cause of early graft failure, while TG is the most prevalent cause of late graft failure. | Sandesh Parajuli Fahad Aziz Neetika Garg Sarah E Panzer Emily Joachim Brenda Muth Maha Mohamed Justin Blazel Weixiong Zhong Brad C Astor Didier A Mandelbrot Arjang Djamali | 2019 | World Journal of Transplantation2019，9，6： | 2 |
| 4 | Incidence and predictors of glaucoma following surgery for congenital cataract in the first year of life in V ictoria, A ustralia显示文摘 | Jonathan B Ruddle Sandra E Staffieri Jonathan G Crowston Justin C Sherwin David A Mackey | 2013 | Clin Experiment Ophthalmol2013，，7： | 1 |
| 5 | Competitive formation of polymer cyclodextrin inclusion compounds显示文摘 | Cristian C Rusa Justin Fox Alan E Tonelli | 2003 | Macromolecules2003，36，： | 1 |
| 6 | The utility of nal and transformational leadership for pre- performance and satisfaction within a theory framework显示文摘 | Vecchio transactlo dicting path-goal R P Justin J E Pearce C L | 2008 | Journal of Occupatio- nal and Organizational Psychology2008，81，1： | 1 |
| 7 | The death effector domain protein family显示文摘 | Bryan C Barnhart Justine C Lee Elizabeth C Alappat | 2003 | Oncogene2003，22，53： | 1 |
| 8 | Association of IL8,CXCR2 and TNF-a polymorphisms and airway disease显示文摘 | Melanie C Justine A | 2006 | J Hum Genet2006，51，： | 1 |
| 9 | Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non- steroidal anti-inflammatory drugs: a randomised trial显示文摘 | Francis K L Chan F R Justin C Y | 2002 | Lancet2002，359，1： | 1 |
| 10 | Positive and nega- tive impacts of specialty malts on beer foam: a comparison of various ce- real products for their foaming properties显示文摘 | ALEXANDER L C JUSTIN K A CHARLES W B | 2013 | J Sei Food Agr2013，93，9： | 1 |
| 11 | Incidence and impact of axial malformations in larval bullfrogs(Rana catesbeiana)developing in sites polluted by a coal-burning power plant显示文摘 | William AH Justin C John KR | 2000 | Environmental Toxicology and Chemistry2000，19，4： | 1 |
| 12 | Strategic Leadership for Explorationand Exploitation:The Moderating Role of Environmental Dynamism显示文摘 | Justin J P Dusya V Mary C | 2009 | The Leadership Quarterly2009，20，： | 1 |
| 13 | Reference genome sequence of the model plant Setaria显示文摘 | Jeffrey L Bennetzen Jeremy Schmutz Hao Wang RyanPercifield Jennifer Hawkins Ana C Pontaroli Matt Estep Liang Feng Justin N Vaughn Jane Grimwood JerryJenkins Kerrie Barry Erika Lindquist Uffe Hellsten Shweta Deshpande Xuewen Wang Xiaomei Wu ThereseMitros Jimmy Triplett Xiaohan Yang Chu-Yu Ye Margarita Mauro-Her-rera Lin Wang Pinghua Li ManojSharma Rita Sharma Pamela C Ronald Olivier Panaud Elizabeth A Kellogg Thomas P Brutnell Andrew NDoust Gerald A Tuskan Daniel Rokhsar Katrien MDevos | 2012 | Nature Biotechnology2012，，30： | 1 |
| 14 | Structural elucidation and quantification of phenolic conjugates present in human urine after tea intake 显示文摘 | Justin J J Ric C H Velitchka M | 2012 | Anal Chem2012，84，： | 1 |
| 15 | Transmitter diversity for OFDM systems and its impact on high-rate data wireless networks显示文摘 | Justin C Chuang Nelson R Sollenberger | 1999 | IEEE Journal on SAC1999，17，7： | 1 |
| 16 | Entopic perimetry screening for central disbetic scotomas and macular edema显示文摘 | Justin C Brown MD Jan A | 2000 | Ophthalmology2000，107，8： | 1 |
| 17 | Oriented astroglial cell growth on micropatterned polystyrene substrates显示文摘 | JENNIFER B RECKNOR JUSTIN C RECKNOR DONALD S SAKAGUCHI | 2004 | Biomaterials2004，25，： | 1 |
| 18 | Empowering Leadership: An Examination of Mediating Mechanisms within a Hierarchical Struc- ture 显示文摘 | Vecchio R P Justin J E Pearce C L | 2010 | The Leadership Quarterly2010，21，3： | 1 |
| 19 | Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis显示文摘 | Alice T Shaw Beow Y Yeap Benjamin J Solomon Gregory J Riely Justin Gainor Jeffrey A Engelman Geoffrey I Shapiro Daniel B Costa Sai-Hong I Ou Mohit Butaney Ravi Salgia Robert G Maki Marileila Varella-Garcia Robert C Doebele Yung-Jue Bang Kimary Kulig Pauli | 2011 | Lancet Oncology2011，，11： | 1 |
| 20 | Electrochemical evaluation of mo-lybdenum disulfide as a catalyst for hydrogen evolution in microbialelectrolysis cells 显示文摘 | Justin C Tokash Bruce E Logan | 2011 | International journal of hydrogen energy2011，36，： | 1 |
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