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| 1 | Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases显示文摘在各种各样的纸巾的 microRNAs (miRNAs ) 的 Dysregulated 表示与许多疾病被联系了,包括癌症。这里,我们证明 miRNAs 在象老鼠,老鼠,牛的胎儿,小牛,和马那样的人和另外的动物的浆液和血浆是在场的。在浆液的 miRNAs 的层次在一样的种类的个人之中稳定、可再现、一致。采用 Solexa,我们定序健康中国题目的所有浆液 miRNAs 并且分别地在男、女的题目发现超过 100 和 91 浆液 miRNAs。我们也为肺癌症, colorectal 癌症,和糖尿病识别了浆液 miRNAs 的特定的表示模式,提供证据那浆液 miRNAs 为各种各样的疾病包含指纹。癌症特定的浆液 miRNAs 由 Solexa 获得了的二个非小的房间肺进一步在 75 个健康施主和 152 个癌症病人的独立审判被验证,用量的反向的抄写聚合酶链反应试金。通过这些分析,我们断定浆液 miRNAs 能为各种各样的癌症和另外的疾病的察觉用作潜在的 biomarkers。 | Xi Chen Yi Ba Lijia Ma Xing Cai Yuan Yin Kehui Wang Jig ang Guo Yujing Zhang Jiangning Chen Xing Guo Qibin Li Xiaoying Li Wenjing Wang Yan Zhang Jin Wang Xueyuan Jiang Yang Xiang Chen Xu Pingping Zheng Juanbin Zhang Ruiqiang Li Hongjie Zhang Xiaobin Shang Ting Gong Guang Ning Jun Wang Ke Zen Junfeng Zhang Chen-Yu Zhang | 2008 | Cell Research2008,18,10: | 975 |
| 2 | Exogenous plant MIR168a specifically targets mammalian LDLRAPI: evidence of cross-kingdom regulation by microRNA显示文摘 | Lin Zhang Dongxia Hou Xi Chen Donghai Li Lingyun Zhu Yuj ing Zhang Jing Li Zhen Bian Xiangying Liang Xing Cai Yuan Yin Cheng Wang Tianfu Zhang Dihan Zhu Dianmu Zhang Jie Xu Qun Chen Yi Ba Jing Liu Qiang Wang Jianqun Chen Jin Wang Meng Wang Qipeng Zhang Junfeng Zhang Ke Zen Chen-Yu Zhang | 2012 | Cell Research2012,22,1: | 155 |
| 3 | Honeysuckle-encoded atypical microRNA2911 directly Largets influenza A viruses显示文摘 | Zhen Zhou Xihan Li Jinxiong Liu Lei Dong Qun Chen Jialing Liu Huihui Kongt Qianyi Zhang Xian Qi Dongxia Hou Lin Zhang Guoquan Zhang Yuchen Liu Yujing Zhang Jing Li Jin Wang Xi Chen Hua Wang Junfeng Zhang Hualan Chen Ke Zen Chen-Yu Zhang | 2015 | Cell Research2015,25,1: | 104 |
| 4 | Delamination and destruction of the North China Craton显示文摘This article presents an overview on recent developments in studies of chemical and physical processes of lithospheric delamination with respect to destruction of the North China Craton. It is emphasized that the pyroxenite source resulting from interaction between eclogite-derived melt and peridotite is a direct consequence of delamination. The pyroxenite source thus formed has unique mineralogical and geochemical features, which characterize Mesozoic basalts of the North China Craton. Melt-peridotite interaction played an important role in refertilization of cratonic lithospheric mantle, leading to density increase, weakening and final destabilization of the North China Craton. The nature of the melt is the key to distinguish mechanisms of destructing this craton. | GAO Shan ZHANG JunFeng XU WenLiang LIU YongSheng | 2009 | Chinese Science Bulletin2009,54,19: | 53 |
| 5 | Levels,sources and health risks of carbonyls and BTEX in the ambient air of Beijing,China显示文摘The atmospheric concentrations of carbonyls and BTEX (benzene,toluene,ethylbenzene,m,p-xylene and o-xylene) were measured simultaneously at a same sampling site in Beijing from September 2008 to August 2010.The average concentrations of the total measured carbonyls during autumn,winter,spring,and summer were 37.7,31.3,39.7,50.5 μg/m 3,respectively,and maximal values for their diurnal variations usually happened at noontime.In contrast to carbonyls,the average concentrations of the total measured BTEX during the four seasons were 27.2,31.9,23.2,19.1 μg/m 3,respectively,andminimal values for their diurnal variations always occurred in the early afternoon.The average concentration for carbonyls increased about 24% from September 2008-August 2009 to September 2009-August 2010,for BTEX,increased about 15%.Integrated life time cancer risks for three carcinogens (benzene,formaldehyde and acetaldehyde) in Beijing exceeded the value of 1E-06,and the hazard quotient (HQ) of non-cancer risk of exposure to formaldehyde exceeded unity. | Yujie Zhang Yujing Mu Junfeng Liu Abdelwahid Mellouki | 2012 | Journal of Environmental Sciences2012,24,1: | 55 |
| 6 | The Sunway TaihuLight supercomputer: system and applications显示文摘The Sunway Taihu Light supercomputer is the world's first system with a peak performance greater than 100 PFlops. In this paper, we provide a detailed introduction to the Taihu Light system. In contrast with other existing heterogeneous supercomputers, which include both CPU processors and PCIe-connected many-core accelerators(NVIDIA GPU or Intel Xeon Phi), the computing power of Taihu Light is provided by a homegrown many-core SW26010 CPU that includes both the management processing elements(MPEs)and computing processing elements(CPEs) in one chip. With 260 processing elements in one CPU, a single SW26010 provides a peak performance of over three TFlops. To alleviate the memory bandwidth bottleneck in most applications, each CPE comes with a scratch pad memory, which serves as a user-controlled cache. To support the parallelization of programs on the new many-core architecture, in addition to the basic C/C++and Fortran compilers, the system provides a customized Sunway Open ACC tool that supports the Open ACC2.0 syntax. This paper also reports our preliminary efforts on developing and optimizing applications on the Taihu Light system, focusing on key application domains, such as earth system modeling, ocean surface wave modeling, atomistic simulation, and phase-field simulation. | Haohuan FU Junfeng LIAO Jinzhe YANG Lanning WANG Zhenya SONG Xiaomeng HUANG Chao YANG Wei XUE Fangfang LIU Fangli QIAO Wei ZHAO Xunqiang YIN Chaofeng HOU Chenglong ZHANG Wei GE Jian ZHANG Yangang WANG Chunbo ZHOU Guangwen YANG | 2016 | Science China(Information Sciences)2016,59,7: | 45 |
| 7 | TRICHOMEAND ARTEMISININ REGULATOR 1 Is Required for Trichome Development and Artemisinin Biosynthesis in Artemisia annua显示文摘毛状体,许多植物种类的表面上的小伸出,能生产并且存储各种各样的第二等的新陈代谢的产品。Artemisinin,最著名并且为疟疾的有势力药,被综合,存储,并且由 Artemisia annua 毛状体藏匿了。然而,糟糕在 A.annua 遗体调整 artemisinin 的生合成和毛状体的发展的分子的基础理解。这里,我们报导那一个 AP2 抄写因素,毛状体和 ARTEMISININ 管理者 1 (TAR1 ) ,在在 A.annua 调整毛状体的发展和 artemisinin 的生合成起关键作用。TAR1,编码特殊位于原子核的蛋白质,主要在年轻叶子,花芽,和一些毛状体被表示。在 TAR1-RNAi 线,毛状体的形态学和表皮的蜡的作文被改变,并且 artemisinin 内容戏剧性地被减少它能被 TAR1 oeverexpression 显著地增加。当 TAR1 是 silenced 或 overexpressed 时,涉及 artemisinin 生合成的几关键基因的表示层次被改变。由 electrophoretic 活动性移动,酵母一个混血儿和短暂转变 -glucuronidase 试金,我们证明广告和 CYP71AV1,在 artemisinin 的生合成小径的二关键基因,是可能的 TAR1 的直接目标。一起拿,我们的结果显示 TAR1 是在 A.annua 调整毛状体开发和 artemisinin 生合成的分子的网络的一个关键部件。 | Hexin Tan Ling Xiao Shouhong Gao Qing Li Junfeng Chen Ying Xiao Qian Ji Ruibing Chen Wansheng Chen Lei Zhang | 2015 | Molecular Plant2015,8,9: | 37 |
| 8 | Preliminary Results of In-situ Stress Measurements along the Longmenshan Fault Zone after the Wenchuan M_s 8.0 Earthquake显示文摘Four months after the Wenchuan M_s 8 earthquake in western Sichuan,China,in situ stress measurements were carried out along the Longmenshan fault zone with the purpose of obtaining stress parameters for earthquake hazard assessment.In-situ stresses were measured in three new boreholes by using overcoring with the piezomagnetic stress gauges for shallow depths and hydraulic fracturing for lower depths.The maximum horizontal stress in shallow depths(~20 m) is about 4.3 MPa,oriented N19°E,in the epicenter area at Yingxiu Town,about 9.7 MPa,oriented N51°W,at Baoxing County in the southwestern Longmenshan range,and about 2.6 MPa,oriented N39°E,near Kangding in the southernmost zone of the Longmenshan range.Hydraulic fracturing at borehole depths from 100 to 400 m shows a tendency towards increasing stress with depth.A comparison with the results measured before the Wenchuan earthquake along the Longmenshan zone and in the Tibetan Plateau demonstrates that the stress level remains relatively high in the southwestern segment of the Longmenshan range,and is still moderate in the epicenter zone.These results provide a key appraisal for future assessment of earthquake hazards of the Longmenshan fault zone and the aftershock occurrences of the Wenchuan earthquake. | WU Manlu ZHANG Yueqiao LIAO Chunting CHEN Qunce MA Yinsheng WU Jinsheng YAN Junfeng OU Mingyi | 2009 | Acta Geologica Sinica(English Edition)2009,83,4: | 31 |
| 9 | Holocene vegetational and climatic variation in westerly-dominated areas of Central Asia inferred from the Sayram Lake in northern Xinjiang,China显示文摘Changes in the vegetation and climate of the westerly-dominated areas in Central Asia during the Holocene were interpreted using pollen-assemblages and charcoal data from a 300-cm-long sediment core of the Sayram Lake,northern Xinjiang.Accele-rator Mass Spectrometry(AMS) radiocarbon dating methods were applied to bulk organic matter of the samples.Artemisia spp./Chenopodiaceae ratios and results from principal component analysis were used to infer that the lake basin was dominated by desert vegetation before ca.9.6 cal.ka BP,which suggests a warm and dry climate in the early Holocene.Desert steppe/steppe expanded during 9.6-5.5 cal.ka BP,indicating a remarkable increase both in the precipitation and temperature during the mid-Holocene.Desert vegetation dominated between 6.5 and 5.5 cal.ka BP,marking an extreme warmer and drier interval.The steppe/meadow steppe recovered,and temperatures decreased from 5.5 cal.ka BP in the late Holocene,as indicated by the increased abundance of Artemisia and the development of meadows.Holocene temperatures and moisture variations in the Sayram Lake areas were similar to those of adjacent areas.This consistency implies that solar radiation was the main driving factor for regional temperature changes,and that the effect of temperature variations was significant on regional changes in humidity.The evolution of climate and environment in the Sayram Lake areas,which were characterized as dry in the early Holocene and relatively humid in the middle-late Holocene,are clearly different from those in monsoonal areas.Dry conditions in the early Holocene in the Sayram Lake areas were closely related to decreased water vapor advection.These conditions were a result of reduced westerly wind speeds and less evaporation upstream,which in turn were caused by seasonal changes in solar radiation superimposed by strong evaporation following warming and drying local climate. | JIANG QingFeng JI JunFeng SHEN Ji Ryo MATSUMOTO TONG GuoBang QIAN Peng REN XueMei YAN DeZhi | 2013 | Science China Earth Sciences2013,56,3: | 32 |
| 10 | Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth显示文摘 | Yuan Yin Xing Cai Xi Chen Hongwei Liang Yujing Zhang Jing Li Zuoyun Wang Xiulan Chen Wen Zhang Seiji Yokoyama Cheng Wang Liang Li Limin Li Dongxia Hou Lei Dong Tao Xu Takachika Hiroi Fuquan Yang Hongbin Ji Junfeng Zhang Ke Zen Chen-Yu Zhang | 2014 | Cell Research2014,24,10: | 33 |
| 11 | Ordovician graptolite-bearing strata in southern Jiangxi with a special reference to the Kwangsian Orogeny显示文摘The Ordovician graptolite sequence of the Yongxin-Chongyi area in southern Jiangxi was suggested as a standard for the correlation of Ordovician in the Zhujiang region of South China. Based on a restudy of the Upper Ordovician graptolites, the Shikou and Huamianlong formations are recognized herein as a part of the Hanjiang Formation, corresponding only to the Dipla-canthograptus caudatus-Diplacanthograptus spiniferus Zone. Two graptolite zones in the Longxi Formation of Yongxin and Chongyi, the Nemagraptus gracilis Zone and Climacograptus bicornis Zone, are redefined here. A rapid replacement of facies from the typical deep-water graptolitic black shale of Longxi Formation to the rapidly-accumulated, shallow-water clastic deposits of Hanjiang Formation indicates the tectonic initiation of the Kwangsian Orogeny. The thick clastic deposits of the Han-jiang Formation are proposed to come from a nearby source area that rose during the Kwangsian Orogeny. The D. caudatus-D. spiniferus graptolite Zone of the Hanjiang Formation indicates the initiation time of this tectonic event. | Xu Chen YuanDong Zhang JunXuan Fan JunFeng Cheng QiJian Li | 2010 | Science China Earth Sciences2010,53,11: | 29 |
| 12 | Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products显示文摘最近的婴儿的公式奶粉污染事件证明了在牛奶质量控制的经典标记或标准在识别鈥渕a nipulated 鈥 ? 是不够的差质量的牛奶。在现在的学习,我们第一次证明奶牛牛奶包含大量 microRNAs ( miRNAs )并且牛奶特定的 miRNAs 的唯一的表示侧面能为未加工的牛奶和牛奶相关的商业产品的质量控制用作新奇指示物和可能的新标准,例如液体牛奶和粉状的公式牛奶。用定序的 Solexa,首先,我们系统地在未加工的牛奶屏蔽了 miRNA 表示并且在未加工的牛奶识别了 245 miRNAs 的一个总数。不同于层次在哺乳的不同时期是其表达式将近相同的另外的经典 biomarkers,单个 miRNAs 能显著地在哺乳过程期间被改变,含有那 miRNAs 可以是更精确的指示物反映牛奶的优秀改变。第二,使用 TaqMan 基于探查的 miRNA 量的 RT-PCR ,我们进一步识别了七 miRNAs 重要地在整个哺乳过程,和更多有相对一致的表情,这七牛奶特定的 miRNAs 的表示侧面能为区别用作理想的 biomarker 差质量或从纯未加工的牛奶的 鈥渕a nipulated 鈥?牛奶,象为商业乳制品的质量控制一样,例如液体,牛奶和粉状的公式挤。一起,我们的调查结果为为决定未加工的牛奶或牛奶相关的商业产品的质量理解牛奶 miRNAs 和一个新潜在的标准的生理的角色提供一个基础。 | Xi Chen Chao Gao Haijin Li Lei Huang Qi Sun Yanye Dong Chunliang Tian Shengpu Gao Hailin Dong Danping Guan Xiaoyun Hu Shujian Zhao Liang Li Lin Zhu Qiao Yan Junfeng Zhang Ke Zen Chen-Yu Zhang | 2010 | Cell Research2010,20,10: | 29 |
| 13 | Interspecific hybridization of Helicoverpa armigera and H.assulta (Lepidoptera:Noctuidae)显示文摘Reciprocal hybridization between Helicoverpa armigera (Hubner) and H. assulta Guenee followed by back-crossing of the hybrids (F1) with H. armigera produced backcross (BC) lines consisting of fertile females and males. The F1 of H. armigera female and H. assulta male had only male, no female sex. In this case Haldane’s rule applies, and therefore it is proved that the sex chromosomes of Helicoverpa species are of ZW type, and the female is the heterozygous sex. This hybrid also showed significant het-erosis with the heaviest pupal weight, and when it was back-crossed with H. armigera female, the sex ratio of the BC offspring was distorted as 1 : 4. The potential utilization of this hybrid in genetic controlling H. armigera was finally discussed. | Chenzhu Wang Junfeng Dong | 2001 | Chinese Science Bulletin2001,46,6: | 24 |
| 14 | Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome based on NMR techniques显示文摘Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome has been performed by comparison with those of normal rats based on NMR techniques. The relative contents of formate,creatinine,2-oxoglutarate(2-OG) ,citrate,taurine,trimethylamine-N-oxide(TMAO) ,succinate and hippurate in the urine of the rats with Qi deficiency and blood stasis syndrome have been changed. These results have provided evidence for understanding the mechanism and the therapy of Qi defi-ciency and blood stasis syndrome. | LI Lin WANG JianNong REN JianXun XIANG JunFeng TANG YaLin LIU JianXun HANDing | 2007 | Chinese Science Bulletin2007,52,22: | 21 |
| 15 | Diverse modes of clonal evolution in HBV-related hepatocellular carcinoma revealed by single-cell genome sequencing显示文摘Hepatocellular 癌(HCC ) 是癌症实质词法,基因并且 phenotypic 差异。然而,我们不理解在 intratumor 异质和肿瘤的联系词法 / 组织学的特征之间的关系。用介绍 96 个肿瘤房间(30-36 各个) 和 15 个正常的肝房间(5 各个) 的单个房间的整个染色体的定序,与联系 HBV 的 HCC 从三个男病人收集了,我们证实拷贝数字变化在 hepatocarcinogenesis 早发生,但是此后在整个肿瘤仍然保持相对稳定前进。重要地,我们证明特定的 HCC 能具有 monoclonal 或 polyclonal 起源。有汇合的 multinodular 形态学的肿瘤是典型 polyclonal 肿瘤并且显示最高的 intratumor 异质。除了 mutational 和拷贝数字侧面,我们把了用导出 HBV 的外国 genomic 标记的 HCC 的同种细胞的起源。在 monoclonal HCC,所有肿瘤单身者房间展出一样的 HBV 集成,显示 HBV 集成是一个早司机事件并且在肿瘤前进期间仍然保持极其稳定。另外,我们的结果显示那两个都转移,迟了的传播并且早播种当模特儿,在 HCC 有一个角色前进。尤其是,开始的克隆传播的早 intrahepatic 导致同步 multifocal 肿瘤的形成。同时,我们在 HCC 识别了潜在的司机基因 ZNF717,它展出变化的高频率在单个房间并且人口铺平,,通过调整 IL-6/STAT3 小径行动的肿瘤 suppressor。这些调查结果热点多重不同肿瘤在 HCC 的进化机制,它为特定的处理策略建议需要。 | Meng Duan, Shu Zhang, Zhichao Wang, Jieyi Shi, Longzi Liu, Xiaoying Wang, Aiwu Ke, Jian Zhou, Jia Fan, Qiang Gao Junfeng Hao, Chong Li Sijia Cui Daniel L Worthley Ya Cao Ruibin Xi Xiaoming Zhang Jian Zhou, Jia Fan Qiang Gao | 2018 | Cell Research2018,28,3: | 21 |
| 16 | Tongue coating microbiome as a potential biomarker for gastritis including precancerous cascade显示文摘The development of gastritis is associated with an increased risk of gastric cancer. Current invasive gastritis diagnostic methods are not suitable for monitoring progressIn this work based on 78 gastritis patients and 50 healthy individuals, we observed that the variation of tongue-coating microbiota was associated with the occurrenee and development of gastritis. Twenty-one microbial species were identified for differentiating tongue-coating microbiomes of gastritis and healthy individuals. Pathways such as microbial metabolism in diverse environments, biosynthesis of antibiotics and bacterial chemotaxis were up-regulated in gastritis patients. The abundance of Campylobacter concisus was found associated with the gastric precancerous cascade. Furthermore, Campylobacter concisus could be detected in tongue coating and gastric fluid in a validation cohort containing 38 gastritis patients. These observations provided biological evidence of tongue diagnosis in traditional Chinese medicine, and indicated that tongue-coating microbiome could be a potential non-invasive biomarker, which might be suitable for long-term monitoring of gastritis. | Jiaxing Cui Hongfei Cui Mingran Yang Shiyu Du Junfeng Li Yingxue Li Liyang Liu Xuegong Zhang Shao Li | 2019 | Protein & Cell2019,10,7: | 21 |
| 17 | Temporo-spatial Coordinates of Evolution of the Ordos Basin and Its Mineralization Responses显示文摘摘要:Ordos 盆被开发从中间迟了对早白垩纪三叠纪,然后自从迟了的白垩纪,进入了它的以后的改革时期。它的主要身体忍受 intra-cratonic 盆的特征。盆也属于在大规模盆上重叠了的多迭加的盆早并且晚古生代。当前, Ordos 盆成为了剩余盆各种各样的式样的富有经验的改革自从迟了的白垩纪。它建议了有在盆的进化期间存在的构造变丑的至少四个明显的阶段,把进化和沉积划分成四个阶段。优先二个阶段具有最繁荣,在哪个期间湖盆是宽广的,免职范围多于比当前的剩余盆两次大,导致主要含有石油、忍受煤的阶层。二个阶段被分开由地区性高举在区域的变化。在 Yan'an 阶段的结束, depositional 打断和侵蚀正在持续时间的一个短时期。第三是中间 -- 侏罗记并且 Zhiluo 舞台,沉积程度仍然在是宽广的但是湖区域显然被减少。在迟了的侏罗记构造变丑是集中的。当不同厚度的集团企业在东方方面的 foredeep 以内被积累时,一条戳越过水坝落下的水带在盆的西方的边缘上被形成。盆的中央、东方的部分服从于侵蚀和改革。一个地区性的框架与在西方在东方和消沉高举黄河向西在区域形成了。在早白垩纪,沉积广泛地被散布, unconformably 重叠北、南部的边阶上的以前的西方的边缘戳带和山脉。象在 Ordos 盆形成的油,天然气,煤和铀存款那样有丰富的精力资源。产生的主要阶段,矿化作用并且资源有明显的反应的多重精力放在 Ordos 中生代和新生代进化和改革与那些联合关系的连接和结束盆。 | LIU Chiyang ZHAO Hongge ZHAO Junfeng WANG Jianqiang ZHANG Dongdong YANG Minghui | 2008 | Acta Geologica Sinica(English Edition)2008,82,6: | 20 |
| 18 | Eclogite-melt/peridotite reaction: Experimental constrains on the destruction mechanism of the North China Craton显示文摘To study the mechanism of melt-peridotite reaction pertinent to the destruction of the North China Craton (NCC) lithosphere, a series of experiments were performed at a pressure of 2.0 GPa and temperatures from 1250 to 1400°C using Bixiling eclogite and Damaping peridotite as starting materials. The experimental results show that the reaction between eclogite melt and peridotite causes dissolution of olivine and orthopyroxene and precipitation of clinopyroxene in the melt. The experimental run products, characterized by a lherzolite/pyroxenite/garnet-pyroxenite sequence, are consistent with the mantle xenoliths in the Neogene Hannuoba basalt of the NCC found by Liu et al. (2005). It suggests that the mafic lower continental crust was probably recycled into the mantle during the Mesozoic Era. In the experiments conducted at 1300 and 1350°C, the resulting melts have a high Mg# andesite signature, indicating that the melt-peridotite reaction may have played a major role in the generation of high Mg# andesite. Our experimental results support the hypothesis that melts derived from foundered eclogite in the asthenosphere will consume the lithospheric peridotites. Therefore, melt-peridotite reaction is an important mechanism for the destruction/thinning of the lithosphere. | WANG Chao JIN ZhenMin GAO Shan ZHANG JunFeng ZHENG Shu | 2010 | Science China Earth Sciences2010,53,6: | 17 |
| 19 | Antigenic variation of the human influenza A(H3N2) virus during the 2014–2015 winter season显示文摘The human influenza A(H3N2) virus dominated the 2014–2015 winter season in many countries and caused massive morbidity and mortality because of its antigenic variation. So far, very little is known about the antigenic patterns of the recent H3N2 virus. By systematically mapping the antigenic relationships of H3N2 strains isolat ed since 2010, we discov ered that two groups with obvious antigenic divergence, named SW13(A/Switzerland/9715293/2013-like strains) and HK14(A/Hong Kong/5738/2014-like strains), co-circulated during the 2014–2015 winter season. HK14 group co-circulated with SW13 in Europe and the United States during this season, while there were few strains of HK14 in China's Mainland, where SW13 has dominated since 2012. Furthermore, we found that substitutions near the receptor-binding site on hemagglutinin played an important role in the antigenic variation of both the groups. These findings provide a comprehensive understanding of the recent antigenic evolution of H3N2 virus and will aid in the selection of vaccine strains. | HUA Sha LI XiYan LIU Mi CHENG YanHui PENG YouSong HUANG WeiJuan TAN MinJu WEI HeJiang GUO JunFeng WANG DaYan WU AiPing SHU YueLong JIANG TaiJiao | 2015 | Science China(Life Sciences)2015,58,9: | 17 |
| 20 | Au/LaVO_(4)Nanocomposite:Preparation,Characterization,and Catalytic Activity for CO Oxidation显示文摘The size of the gold particles is a very important parameter to get active catalysts.This paper reports a novel colloidal deposition method to prepare Au/LaVO_(4)nanocomposite catalyst with monodispersed Au colloids and uniform LaVO_(4)nanoplates in nonpolar solvent.Monodispersed Au colloids with tunable size(such as 2,5,7,11,13,and 16 nm)and LaVO_(4)nanocrystals with well-defi ned shapes were pre-synthesized assisted with oleic acid/amine.During the following immobilization process,the particle size and shape of Au and LaVO_(4)were nearly preserved.As-prepared Au/LaVO_(4)nanocomposite showed high catalytic activity for CO oxidation at room temperature.Since sizes of gold particles were well-defi ned before the immobilization process,size effect of gold particles was easy to be investigated and the results show that 5-nm Au/LaVO_(4)nanocomposite has the highest activity for CO oxidation.This synthetic method can be extended further for the preparation of other composite nanomaterials. | Junfeng Liu Wei Chen Xiangwen Liu Kebin Zhou Yadong Li | 2008 | Nano Research2008,1,1: | 16 |