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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Nonexistence of singular pseudo-self-similar solutions of the Navier–Stokes system显示文摘 | Judith R. Miller Mike O’Leary Maria Schonbek | 2001 | Mathematische Annalen2001，，4： | 1 |
| 3 | Combined array- comparative genomic hybridization and single - nucleotide polymorphism - loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer显示文摘 | Judith NK Jan O Tom VW | 2007 | BMC Genomics2007，8，： | 1 |
| 4 | The synthesis of graphene sheets with controlled thickness and order using surfactant-assisted electrochemical processes显示文摘 | Murat Alanyal?o?lu Juan Josè Segura Judith Oró-Solè Nieves Casa?-Pastor | 2011 | Carbon2011，，1： | 1 |
| 5 | Chlamydia pneumoniae exposure and inflammatory markers in acute coronary syndrome (CIMACS)显示文摘 | Harish R Chandra Nivedita Choudhary Carol O’Neill Judith Boura Gerald C Timmis William W O’Neill | 2001 | The American Journal of Cardiology2001，，： | 1 |
| 6 | Impact of nephropathy after percutaneous coronary intervention and a method for risk stratification显示文摘 | Beth A Bartholomew Kishore J Harjai Srinivas Dukkipati Judith A Boura Michael W Yerkey Susan Glazier Cindy L Grines William W O’Neill | 2004 | The American Journal of Cardiology2004，，12： | 1 |
| 7 | Angiotensin Ⅱ stimulates cardiac myoeyte hypertrophy via paraerine release of TGT-β1 and endothelin-1 from fibroblasts显示文摘 | Gray Mary O long carlin S kalinyak Judith E | 1998 | Cardiovascular Reseach1998，40，： | 1 |
| 8 | Power spectral analysis of heart-rate variability reflects the level of cardiac autonomic activity in rabbits显示文摘 | Viatcheslav AM Louise S Judith O | 1996 | Journal of the Autonomic Nervous System1996，58，1： | 1 |
| 9 | Tiotropium bromide (Ba 679 BR), a novel long-acting muscarinic antagonist for the treatment of obstructive airways disease显示文摘 | Peter J Barnes Maria G Belvisi Judith C.W. Mak El-Bdaoui Haddad Brian O’Connor | 1995 | Life Sciences1995，，11： | 1 |
| 10 | Gene expression profiling spares early breast cancer patients from adjuvant therapy:derived and validated in two population-based cohorts显示文摘 | Yudi Pawitan Judith Bj(o)hle Lukas Amler | 2005 | Breast Cancer Res2005，7，6： | 1 |
| 11 | Increased uptake of LDL by oxi- dized macrophages is the result of an initial enhanced LDL receptor ac- tivity and of a further progressive oxidation of LDL显示文摘 | Fuhrman B Judith O Keidar S | 1997 | Free Radic Bid Med1997，23，1： | 1 |
| 12 | Peripheral blood hematopoietic stem cells for transplantation of hematological diseases from related, haploidentical donors after reduced-intensity conditioning显示文摘 | Kavita Raj Antonio Pagliuca Kenneth Bradstock Victor Noriega Victoria Potter Matthew Streetly Donal Mclornan Majid Kazmi Judith Marsh John Kwan Gillian Huang Lisa Getzendaner Stephanie Lee Katherine A. Guthrie Ghulam J. Mufti Paul O’Donnell | 2014 | Biology of Blood and Marrow Transplantation2014，，： | 1 |
| 13 | Smoking after acute myocardial infarction a good thing显示文摘 | Ira S O Judith K O | 1993 | Circulation1993，87，： | 1 |
| 14 | Mammalian embryo co-culture : Trials and tribulations of a misunderstood method 显示文摘 | Nicolas M O Judith B R | 2007 | Theriogenology2007，67，： | 1 |
| 15 | Posttransplantation Lymphoproliferative Disorder: Endoscopic Findings显示文摘 | Judith A. O'Connor Catherine Cogley Mark Burton Kristen Lancaster-Weiss Richard A. Cordle | 2000 | Journal of Pediatric Gastroenterology and Nutrition2000，，4： | 1 |
| 16 | Chlorophyll a fluoresceace and carbon assimilation in developing leaves of Light-Grown cucumber显示文摘 | Judith G C Kenji O | 1990 | Plant Physiol1990，93，： | 1 |
| 17 | Interaction of granulocyte colony- stimulating factor(G-CSF) with its receptor显示文摘 | Judith E L Grant S Tim O | 1999 | J Biol Chem1999，274，17： | 1 |
| 18 | Heart Failure/Cardiac Transplantation: Dose-Response of Chronic Beta -Blocker Treatment in Heart Failure From Either Idiopathic Dilated or Ischemic Cardiomyopathy显示文摘 | Michael R. Bristow John B. O’Connell Edward M. Gilbert William J. French George Leatherman Niki E. Kantrowitz Judith Orie Mark L. Smucker Guillermo Marshall Patricia Kelly David Deitchman Jeffrey L. Anderson for The Bucindolol. Investigators | 1994 | Circulation1994，，4： | 1 |
| 19 | Project CARE: A ran- domized controlled trial of a behavioral intervention group for Alzheimer' s disease caregivers 显示文摘 | Judith GG O'Connor MK Patricia AB | 2006 | The Gerontologist2006，46，6： | 1 |
| 20 | Changes in the burden of malaria in sub-Saharan Africa显示文摘 | Wendy Prudhomme O'Meara Judith Nekesa Mangeni Rick Steketee Brian Greenwood | 2010 | The Lancet Infectious Diseases2010，，8： | 1 |
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