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| 1 | Does autologous blood transfusion during liver transplantation for hepatocellular carcinoma increase risk of recurrence?显示文摘AIM: To analyze outcomes in patients who underwent liver transplantation(LT) for hepatocellular carcinoma(HCC) and received autologous intraoperative blood salvage(IBS). METHODS: Consecutive HCC patients who underwent LT were studied retrospectively and analyzed according to the use of IBS or not. Demographic and surgical data were collected from a departmental prospective maintained database. Statistical analyses were performed using the Fisher's exact test and the Wilcoxon rank sum test to examine covariate differences between patients who underwent IBS and those who did not. Univariate and multivariate Cox regression models were developed to evaluate recurrence and death,and survival probabilities were estimated using the Kaplan-Meier method and compared by the log-rank test.RESULTS: Between 2002 and 2012,158 consecutive patients who underwent LT in the same medical center and by the same surgical team were identified. Among these patients,122(77.2%) were in the IBS group and 36(22.8%) in the non-IBS group. The overall survival(OS) and recurrence free survival(RFS) at 5 years were 59.7% and 83.3%,respectively. No differences in OS(P=0.51) or RFS(P=0.953) were detected between the IBS and non-IBS groups. On multivariate analysis for OS,degree of tumor differentiation remained as the only independent predictor. Regarding patients who received IBS,no differences were detected in OS or RFS(P=0.055 and P=0.512,respectively) according to the volume infused,even when outcomes at 90 d or longer were analyzed separately(P=0.518 for both outcomes).CONCLUSION: No differences in RFS or OS were detected according to IBS use. Trials addressing this question are justified and should be designed to detect small differences in long-term outcomes. | Raphael LC Araujo Carlos Andrés Pantanali Luciana Haddad Joel Avancini Rocha Filho Luiz Augusto Carneiro D’Albuquerque Wellington Andraus | 2016 | World Journal of Gastrointestinal Surgery2016，8，2： | 14 |
| 2 | 大型接地体性能的试验研究(英文)显示文摘Analytical and numerical simulation techniques have been developed for the calculation of earth resistance/ impedance and to estimate the potential distribution in the vicinity of earth electrodes.However,very little literature is available on experimental validation of these calculation techniques.To address this,a programme of experimental tests on various earth electrodes has been carried out at the lower water reservoir of a hydro pumped-storage power station in North Wales.In this paper,the earthing test facility at Dinorwig power station is described including the details of the experimental set up.The results from experimental tests on a 5 mX5 m earth grid,immersed in water and energized under ac,dc and impulse,are presented.The values of measured earth resistance/impedance and water surface potential distributions are compared with those obtained from analytical calculations and detailed numerical computer simulations. | D. Guo D. Lathi H. Griffiths N. Harid A. Ainsley A. Haddad | 2011 | 高电压技术2011，37，11： | 11 |
| 3 | 基于表层梯度电导调控的直流三支柱绝缘子界面电场优化方法显示文摘气-固界面和嵌件-环氧界面的电场强度集中效应被认为是导致直流三支柱绝缘子发生沿面闪络和支腿炸裂的重要原因,传统的结构优化难以同时有效调控两个界面的电场分布,迫切需要更合理的调控手段。通过电-热-流多物理场仿真,研究直流三支柱绝缘子界面电场分布特性,指出电荷积聚是造成界面处场强集中的主要原因。据此提出基于“类U型”梯度电导的绝缘子双界面电场联合调控策略,通过嵌件-环氧界面高电导涂层和气-固界面非线性电导涂层的协同使用,使得三支柱绝缘子体电导和表面电导呈“类U型”梯度分布,可降低绝缘子内部及表面电荷积聚程度,从而优化界面电场分布。进一步研究双界面涂层对直流三支柱绝缘子界面电场的调控作用,并针对电场调节与损耗控制目标,实现对涂层电导参数的优化。研究结果表明:当嵌件-环氧界面涂覆材料电导率不小于10^(-12)S/m、气-固界面非线性电导材料参数处于“临界饱和线”上时,支柱绝缘子嵌件-环氧界面最大电场强度可从4.48kV/mm降至0.04kV/mm,气-固界面最大切向电场强度从2.47kV/mm降至1.73kV/mm。参数优化后的双界面梯度电导涂层,可使界面电场集中效应得到有效抑制,同时将绝缘子最大电场与功率损耗控制在允许范围内,为高压直流三支柱绝缘子的优化设计提供了基础依据。 | 胡琦 李庆民 刘智鹏 刘衡 AManu Haddad | 2022 | 电工技术学报2022，37，7： | 9 |
| 4 | Strength properties of soft clay treated with mixture of nano-SiO_2 and recycled polyester fiber显示文摘This paper investigates the effect of recycled polyester fiber, produced from polyethylene(PET) bottles, in combination with nano-Si O2 as a new stabilizer to improve the mechanical properties of soils. We intend to study the effect of adding nano-Si O2 and recycled polyester fiber on soil engineering properties,especially the shear strength and unconfined compressive strength(UCS), using clayey soil with low liquid limit. Three different combinations of fiber-soil ratios ranging between 0.1% and 0.5% as well as three different combinations of nano-soil ratios ranging between 0.5% and 1% are used. The shear strength and UCS of treated specimens are obtained from direct shear test and unconfined compression test, respectively. Results of this study show that the addition of recycled polyester fiber and nano-Si O2 increases the strength of soil specimens. Both the shear strength and UCS are improved by increasing the contents of recycled polyester fiber and nano-Si O2 in the soil mixture. The increase in the nano-Si O2 content leads to a reduction in failure strain, but the increase in the content of recycled polyester fiber leads to an increase in failure strain. The increase in the contents of recycled polyester fiber and nanoSi O2 leads to an increase in elastic modulus of soils. Based on the test results, the addition of recycled polyester fiber improves the mechanical properties of soils stabilized with nano-Si O2 as well as the recycled polyester fiber has a positive effect on soil behaviors. | Foad Changizi Abdolhosein Haddad | 2015 | Journal of Rock Mechanics and Geotechnical Engineering2015，7，4： | 7 |
| 5 | Review of evolution of tunnel position in anterior cruciate ligament reconstruction显示文摘Anterior cruciate ligament(ACL) rupture is one of the commonest knee sport injuries. The annual incidence of the ACL injury is between 100000-200000 in the United States. Worldwide around 400000 ACL reconstructions are performed in a year. The goal of ACL reconstruction is to restore the normal knee anatomy and kinesiology. The tibial and femoral tunnel placements are of primordial importance in achieving this outcome. Otherfactors that influence successful reconstruction are types of grafts, surgical techniques and rehabilitation programmes. A comprehensive understanding of ACL anatomy has led to the development of newer techniques supplemented by more robust biological and mechanical concepts. In this review we are mainly focussing on the evolution of tunnel placement in ACL reconstruction, focusing on three main categories, i.e., anatomical, biological and clinical outcomes. The importance of tunnel placement in the success of ACL reconstruction is well researched. Definite clinical and functional data is lacking to establish the superiority of the single or double bundle reconstruction technique. While there is a trend towards the use of anteromedial portals for femoral tunnel placement, their clinical superiority over trans-tibial tunnels is yet to be established. | Faizal Rayan Shashi Kumar Nanjayan Conal Quah Darryl Ramoutar Sujith Konan Fares S Haddad | 2015 | World Journal of Orthopedics2015，6，2： | 7 |
| 6 | Chronic ischemic mitral valve regurgitation and surgical perspectives显示文摘Chronic ischemic mitral valve regurgitation is a result of disturbed left ventricular geometry secondary to myocardial ischemia in the absence of intrinsic mitral valve pathology. It is a common complication after myocardial infarction, and patients who have ischemic mitral regurgitation(IMR) have a worse prognosis compared to patients who have ischemic heart disease alone, and this is directly related to the severity of IMR. Medical therapy has limited efficacy, and surgical options including various repair techniques and valve replacement had been tried with variable success. Still there is intense debate among surgeons whether to interfere with moderate degree IMR at the time of coronary artery revascularization. | Salah Eldien Altarabsheh Salil V Deo Abeer Rababa'h Yagthan M Obeidat Osama Haddad | 2018 | World Journal of Cardiology2018，10，10： | 5 |
| 7 | Chronic permanent hypoxemia predisposes to mild elevation of liver stiffness显示文摘AIM:To evaluate the impact of long term permanent hypoxemia noticed in patients with non operated congenital cyanogenic cyanotic cardiopathy on liver stiffness.METHODS:We included ten adult patients with non operated inoperate cyanotic cardiopathy and ten matched patients for age and gender admitted to the gastroenterology department for proctologic diseases;Clinical and laboratory data were collected[age,gender,body mass index,oxygen saturation,glutamate oxaloacetate transaminase(GOT),glutamate pyruvate transaminase(GPT),glycemia and cholesterol].Measurement of hepatic stiffness by transient elastography was carried out in all patients using the Fibroscan device.All patients underwent an echocardiography to eliminate congestive heart failure.RESULTS:Among the patients with cyanotic cardiopathy,median liver stiffness 5.9±1.3 kPa was greater than control group(4.7±0.4 kPa)(P=0.008).Median levels of GOT,GPT,gamma-glutamyltransferase,glycemia and cholesterol were comparable in cardiopathy and control group.In regression analysis including age,gender,body mass index,oxygen saturation,GOT,GPT,glycemia,cholesterol showed that only oxygen saturation was related to liver stiffness(r=-0.63 P=0.002).CONCLUSION:Chronic permanent hypoxemia can induce mild increase of liver stiffness,but further studies are needed to explore the histological aspects of liver injury induced by chronic permanent hypoxemia. | Mohamed Tahiri Abdenasser Drighil Yasmine Jalal Dounia Ghellab Wafaa Hliwa Haddad Fouad Wafaa Badre Ahmad Bellabah Rachida Habbal Rhimou Alaoui | 2014 | World Journal of Gastroenterology2014，20，30： | 5 |
| 8 | 直流电压下玻璃纤维的荷电运动过程及桥接放电现象显示文摘气体绝缘全封闭组合电器/气体绝缘金属封闭输电线路(gas insulated switchgear/gas insulated metal-enclosed transmission line,GIS/GIL)在制造、运输、装配过程中容易引入绝缘纤维,是造成设备放电故障的原因之一。该文通过搭建封闭式平行电极板实验平台,获得玻璃纤维的启举与运动特性;进一步通过理论计算建立纤维的荷电与受力模型,研究直流电压下玻璃纤维的运动与放电特性。结果表明,玻璃纤维的临界启举电压与纤维直径的1/2次方近似呈正比关系,与纤维长度基本无关。玻璃纤维荷电启举后,在电极间往复运动中会分散成若干纤维簇,而带有不同极性电荷的纤维簇首尾相接,贯通电极,引发“桥接”现象。玻璃纤维的跳动会严重畸变纤维尖端电场,降低气隙的击穿电压,较无纤维时下降约7%~20%。当玻璃纤维出现桥接现象时,放电会沿着纤维小桥表面发生,气隙击穿电压下降约34%。所得结果阐释了直流应力下玻璃纤维的运动行为及放电规律,可为GIS/GIL设备的异物防护提供基础依据。 | 胡琦 李庆民 刘智鹏 刘衡 梁瑞雪 MANU Haddad | 2022 | 中国电机工程学报2022，42，6： | 4 |
| 9 | 界面电荷注入与积聚行为对直流GIS/GIL绝缘子沿面电场的影响分析显示文摘气体绝缘组合电器(gas insulated switchgear,GIS)和气体绝缘金属封闭输电线路(gas insulated metalenclosed transmission line,GIL)运行电流大,设备内部存在明显的温度梯度分布,造成高压电极附近电荷的注入与迁移加剧,导致绝缘子内空间及表面电荷的积聚,畸变电场,容易诱发沿面闪络故障。为此文中建立了电—热耦合应力下直流盆式绝缘子内的电荷注入与积聚模型,研究了考虑电荷注入和迁移特性的绝缘子空间电荷及表面电荷积聚情况,并分析了不同负载电流下绝缘子沿面电场分布规律。研究结果表明:温度梯度下,导体—绝缘界面电荷注入会造成绝缘子内部同极性空间电荷的积聚,并且空间电荷积聚密度会随着负载电流的增大而增大;空间电荷的积聚会减弱高压电极附近电场强度,增强绝缘子凸侧表面法向电场强度,加剧表面电荷的积聚;空间及表面电荷的积聚会使绝缘子表面电势上升,导致接地电极附近电势差增大,电场强度显著增大,地电极三结合点处的场强由空载条件下的1.71 kV/mm增长为额定电流作用下的3.47 kV/mm,增加了103%。该研究结果有助于理解温度梯度下直流绝缘子表面电场畸变机理,并对直流绝缘子的优化设计和安全运行有一定的参考价值。 | 胡琦 刘智鹏 刘衡 李庆民 AManu Haddad | 2021 | 高压电器2021，57，10： | 4 |
| 10 | Randomised controlled trial of triclosan coated vs uncoated sutures in primary hip and knee arthroplasty显示文摘BACKGROUND Triclosan-coated vicryl plus suture(Ethicon, Inc.) was developed to reduce microbial colonisation during surgical procedures. However, its effect on wound healing and surgical site infections remain unclear after hip and knee arthroplasty surgery.AIM To determine the effect of triclosan-coated sutures(TCS) vs non-coated sutures on wound healing, following primary hip and knee arthroplasties.METHODS A single-centred, double-blind randomised controlled trial(RCT) was undertaken. We randomly allocated patients to receive either the triclosan-coated sutures(TCS vicryl plus) or non-coated sutures(NCS vicryl) during the closure of unilateral primary hip and knee arthroplasties. We utilised the ASEPSIS wound scoring system to evaluate wound healing for the first 6 weeks post-operatively.RESULTS One hundred and fifty patients undergoing primary total hip or knee arthroplasty over a one-year period were included. Eighty-one were randomised to the TCS group and 69 to the NCS group. Despite no statistically significant difference in the ASEPSIS scores among the study groups(P = 0.75), sensitivity analysis using the Mann Whitney test(P = 0.036) as well as assessment of the wound complications at 6 weeks follow up, demonstrated significantly higher wound complication rates in the TCS group(8 vs 1, P = 0.03).CONCLUSION No clear advantage was demonstrated for using the TCS. However, larger multicentred RCTs are required to validate their use in hip and knee arthroplasty surgery. | Mohamed Sukeik David George Ayman Gabr Rami Kallala Peter Wilson Fares Sami Haddad | 2019 | World Journal of Orthopedics2019，10，7： | 4 |
| 11 | A randomized open-label trial of on-demand rabeprazole vs ranitidine for patients with non-erosive reflux disease显示文摘AIM:To compare the efficacy of the proton-pump inhibitor,rabeprazole,with that of the H 2-receptor antagonist,ranitidine,as on-demand therapy for relieving symptoms associated with non-erosive reflux disease(NERD).METHODS:This is a single center,prospective,randomized,open-label trial of on-demand therapy with rabeprazole(group A) vs ranitidine(group B) for 4 wk.Eighty-three patients who presented to the American University of Beirut Medical Center with persistent gastroesophageal reflux disease(GERD) symptoms and a normal upper gastrointestinal endoscopy were eligible for the study.Patients in group A(n = 44) were allowed a maximum rabeprazole dose of 20 mg twice daily,while those in group B(n = 39) were allowed a maximum ranitidine dose of 300 mg twice daily.Efficacy was assessed by patient evaluation of global symptom relief,scores of the SF-36 quality of life(QoL) questionnaires,total number of pills used,and number of medication-free days.RESULTS:Among the 83 patients who were enrolled in the study,76 patients(40 in the rabeprazole group and 36 in the ranitidine group) completed the 4-wk trial.Baseline characteristics were comparable between both groups.After 4 wk,there was no significant difference in the subjective global symptom relief between the rabeprazole and the ranitidine groups(71.4% vs 65.4%,respectively;P = 0.9).There were no statistically significant differences between mean cumulative scores of the SF-36 QoL questionnaire for the two study groups(rabeprazole 22.40 ± 27.53 vs ranitidine 17.28 ± 37.06;P = 0.582).There was no significant difference in the mean number of pills used(rabeprazole 35.70 ± 29.75 vs ranitidine 32.86 ± 26.98;P = 0.66).There was also no statistically significant difference in the mean number of medication-free days between both groups.CONCLUSION:Rabeprazole has a comparable efficacy compared to ranitidine when given on-demand for the treatment of NERD.Both medications were associated with improved quality of life. | Abdallah A Kobeissy Jana G Hashash Faek R Jamali Assaad M Skoury Reham Haddad Sarah El-Samad Rami Ladki Rola Aswad Assaad M Soweid | 2012 | World Journal of Gastroenterology2012，18，19： | 4 |
| 12 | Choice of dialysis modality prior to kidney transplantation:Does it matter?显示文摘The population of patients with end stage renal disease(ESRD) is increasing,lengthening waiting lists for kidney transplantation.Majority of the patients are not able to receive a kidney transplant in timely manner even though it is well established that patient survival and quality of life after kidney transplantation is far better when compared to being on dialysis.A large number of patients who desire a kidney transplant ultimately end up needing some form of dialysis therapy.Most of incident ESRD patients choose hemodialysis(HD) over peritoneal dialysis(PD) as the modality of choice in the United States,even though studies have favored PD as a better choice of pre-transplant dialysis modality than HD.PD is largely underutilized in the United States due to variety of reasons.As a part of the decision making process,patients are often educated how the choice regarding modality of dialysis would fit into their life but it is not clear and not usually discussed,how it can affect eventual kidney transplantation in the future.In this article we would like to discuss ESRD demographics and outcomes,modality of dialysis and kidney transplant related events.We have summarized the data comparing PD and HD as the modality of dialysis and its impact on allograft and recipient outcomes after kidney transplantation. | Deepika Jain Danny B Haddad Narender Goel | 2019 | World Journal of Nephrology2019，8，1： | 3 |
| 13 | 针灸可改善乳腺癌患者术后患肢功能障碍显示文摘巴西圣保罗联邦大学的Giron教授等人公布了一项最新研究结果,针灸治疗对乳腺癌患者术后肢体功能障碍的恢复效果显著,具有安全、微创、耐受性好的特点,可减轻乳腺癌患者术后的身心问题,提高其生活质量。该研究共纳入50例18岁以上、术后3个月仍有肩胛带、上肢及颈胸椎疼痛,且视觉模拟评分法(VAS)≥3分的女性乳腺癌患者,排除双侧乳腺切除、转移性肿瘤、静脉炎和肢体触觉感觉障碍、 | 刘少华 王琦 Giron PS Haddad CA Lopes de Almeida Rizzi SK | 2017 | 护士进修杂志2017，32，14： | 3 |
| 14 | 树突状细胞自然杀伤细胞凝集素群受体1促进小鼠动脉粥样硬化的发展显示文摘动脉粥样硬化发展过程中的坏死核心形成与慢性炎症反应有关,其促进斑块发展加快和不稳定。然而,坏死与动脉粥样硬化发展之间的分子生物学联系机制尚未完全清楚。 | 刘莉 叶鹏 Haddad Y Lahoute C Clément M Laurans L Metghalchi S Lynda Z Giraud A Loyer X Vandestienne M Wain-Hobson J Esposito B Potteaux S Ait-Oufella H Tedgui A Mallat Z Taleb S | 2017 | 中华高血压杂志2017，25，8： | 3 |
| 15 | Predicting lower limb periprosthetic joint infections: A review of risk factors and their classification显示文摘AIM To undertook a systematic review to determine factors that increase a patient's risk of developing lower limb periprosthetic joint infections(PJI).METHODS This systematic review included full-text studies that reviewed risk factors of developing either a hip or knee PJI following a primary arthroplasty published from January 1998 to November 2016. A variety of keywords were used to identify studies through international databases referencing hip arthroplasty, knee arthroplasty, infection, and risk factors. Studies were only included if they included greater than 20 patients in their study cohort, and there was clear documentation of the statistical parameter used; specifically P-value, hazard ratio, relative risk, or/and odds ratio(OR). Furthermore a quality assessment criteria for the individual studies was undertaken to evaluate the presence of record and reporting bias. RESULTS Twenty-seven original studies reviewing risk factors relating to primary total hip and knee arthroplasty infections were included. Four studies(14.8%) reviewed PJI of the hip, 3(11.21%) of the knee, and 20(74.1%) reviewed both joints. Nineteen studies(70.4%) were retrospective and 8(29.6%) prospective. Record bias was identified in the majority of studies(66.7%). The definition of PJI varied amongst the studies but there was a general consensus to define infection by previously validated methods. The most significant risks were the use of preoperative high dose steroids(OR = 21.0, 95%CI: 3.5-127.2, P < 0.001), a BMI above 50(OR = 18.3, P < 0.001), tobacco use(OR = 12.76, 95%CI: 2.47-66.16, P= 0.017), body mass index below 20(OR = 6.00, 95%CI: 1.2-30.9, P = 0.033), diabetes(OR = 5.47, 95%CI: 1.77-16.97, P = 0.003), and coronary artery disease(OR = 5.10, 95%CI: 1.3-19.8, P = 0.017).CONCLUSION We have highlighted the need for the provider to optimise modifiable risk factors, and develop strategies to limit the impact of non-modifiable factors. | David A George Lorenzo Drago Sara Scarponi Enrico Gallazzi Fares S Haddad Carlo L Romano | 2017 | World Journal of Orthopedics2017，8，5： | 3 |
| 16 | Where does chemotherapy stands in the treatment of ampullary carcinoma? A review of literature显示文摘Ampullary carcinoma(AC) is a rare gastrointestinal tumor without clear treatment recommendations.The management of this tumor is usually extrapolated from the treatment of pancreatic,biliary duct and intestinal cancers.Few papers have studied the AC as an independent entity and yet succombs to several limitations.These studies were retrospective single institutional experiences with limited sample sizes recruited over a long period of time.Unlike metastatic ACs where chemotherapy is the only recommended option,localized AC once excised may be approached by either chemotherapy alone or concomitant chemoradiation therapy.In this review,we report the overall survival and recurrence factors of more than 1000 patients from all the studies treating exclusively ACs.We also review the medical treatment of this tumor and conclude to the necessity of multi-institutional randomized controlled studies for AC exclusively. | Marwan Ghosn Hampig Raphael Kourie Elie El Rassy Fady Ghassan Haddad Colette Hanna Fadi El Karak Dolly Nasr | 2016 | World Journal of Gastrointestinal Oncology2016，8，10： | 2 |
| 17 | 肺动脉高压患者的负荷适应性显示文摘已知右心室对压力超负荷的适应是肺动脉高压(pulmonary arterial hypertension,PAH)患者预后的主要影响因素。为了评估右心室适应和负荷之间的关系,然后比较PAH中不同负荷适应性指数的预后价值,Amsallem及其同事纳入推导队列(n=85)和验证队列(n=200),使用3种方法评估负荷适应性:①脑室动脉耦合的替代物(例如右心室面积变化/收缩末期面积); | 刘莉 叶鹏 Amsallem M Boulate D Aymami M Guihaire J Selej M Huo J Denault AY McConnell MV Schnittger I Fadel E Mercier O Zamanian RT Haddad F | 2017 | 中华高血压杂志2017，25，8： | 2 |
| 18 | The management of periprosthetic femoral fractures around hip replacements显示文摘 | Eleftherios Tsiridis Fares S. Haddad Graham A. Gie | 2003 | Injury2003，，2： | 2 |
| 19 | 偏心环空中幂率流体层流流动特性数值模拟研究显示文摘Herschel-Bulkley模型(即屈服幂率模型)可用于研究非牛顿流体的流动特性,并能在大范围剪切速率条件下得到准确的预测结果。为此,采用有限体积方法(FVM),研究了内部管柱旋转及流变参数(屈服应力τ0、稠度系数K和流性指数n)对偏心环空(E=0.5)中Herschel-Bulkley流体层流区域的轴向、切向速度剖面与压降梯度的影响。研究结果表明,内部管柱转速从100 r/min增加至400 r/min时,会引起最大轴向速度增加,增幅为120%;较低的流性指数(n=0.2)会引起偏心环空宽区域出现二次流;内部管柱转速及流变参数的变化对偏心环空宽区域切向速度剖面有不良影响;内部管柱转速从0增加至400 r/min时,会引起不同偏心环空(E=0.2,0.4,0.6和0.8)内幂率流体压降梯度降低,降低幅度为10%。 | Hicham Ferroudji Ahmed Hadjadj Titus N Ofei Ahmed Haddad | 2020 | 石油钻探技术2020，48，4： | 2 |
| 20 | Cytokines and the regulation of hypoxia-inducible factor (HIF)-1α显示文摘 | John J. Haddad Hisham L. Harb | 2005 | International Immunopharmacology2005，，3： | 2 |
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