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| 1 | Dysbiotic infection in the stomach显示文摘Microbiota in human alimentary tract plays important roles for homeostatic maintenance of the body. Compositional difference of gut microbiota is tightly associated with susceptibility of many diseases,including inflammatory diseases,obesity,diabetes mellitus,cancer,and atherosclerosis. 'Dysbiosis' refers to a state of imbalance among the colonies of microorganisms within the body,which brings abnormal increase of specific minor components and decrease in the normally dominant species. Since stomach secrets strong acid for its digestive role,this organ has long been thought a sterile organ. However,the discovery of Helicobacter pylori(H. pylori) has changed the concept. This bacterium has proven to cause gastritis,peptic ulcer,and gastric cancer. However,recent cross-sectional studies revealed that H. pylori carriers had a decreased risk of developing immunological diseases,such as asthma. H. pylori coinfection also suppresses inflammatory bowel diseases. This review describes human gastric microbiota by discussing its mutual interaction and pathogenic enrollment. Gastric 'dysbiosis' may affect host inflammatory response and play important role for gastric pathogenesis. We will topically discuss enrollment of dysbiosis for genesis of gastric cancer as well as for disruption of immunological homeostasis affecting oncogenic resistance. | Hisashi Iizasa Shyunji Ishihara Timmy Richardo Yuichi Kanehiro Hironori Yoshiyama | 2015 | World Journal of Gastroenterology2015，21，40： | 5 |
| 2 | Artificial Immune Recognition System (AIRS): An Immune-Inspired Supervised Learning Algorithm显示文摘 | Andrew Watkins Jon Timmis Lois Boggess | 2004 | Genetic Programming and Evolvable Machines2004，，3： | 2 |
| 3 | Diabetes显示文摘 | Timmis AD | 2001 | Br Med Bull2001，59，： | 1 |
| 4 | Artificial immune systems as a novel soft computing paradigm显示文摘 | DE CASTRO LN TIMMIS JI | 2003 | Soft Computing2003，7，8： | 1 |
| 5 | An artificial immune system for data analysis显示文摘 | TIMMIS J NEAL M HUNT J | 2000 | BioSystems2000，55，123： | 1 |
| 6 | Theoretical advances in artificial immune systems显示文摘 | Timmis J Hone A Stibor T Clark E | 2008 | Theoretical Computer Science2008，403，1： | 1 |
| 7 | An artificial immune systemfor data analysis显示文摘 | Jon Timmis Mark Neal John Hunt | 2000 | BioSystem2000，，55： | 1 |
| 8 | Artificial Immune System for Data Analysis显示文摘 | Timmis J Neal T Hunt J | 2000 | Biosystems2000，55，13： | 1 |
| 9 | Application Areas of AIS: The Past, Present and the Future显示文摘 | Hart E Timmis J | 2008 | Journal of Applied Soft Computing2008，8，1： | 1 |
| 10 | A resource limited artificial immune system for data analysis显示文摘 | Timmis J Neal M | 2001 | Knowledge Based Systems2001，14，3： | 1 |
| 11 | The evolution of myocardial ischemia during percutaneous transluminal coronary angioplasty显示文摘 | Griffin B Timmis AD Crick JCP | 1987 | Eur Heart J1987，8，4： | 1 |
| 12 | Towards a framework for teaching spoken grammar显示文摘 | Timmis I | | 0，，02： | 1 |
| 13 | The potential of Bacillus licheniformis strains for in situ enhanced oil recovery显示文摘 | Michail M. Yakimov Mohammed M. Amro Michael Bock Klaus Boseker Herbert L. Fredrickson Dagobert G. Kessel Kenneth N. Timmis | 1997 | Journal of Petroleum Science and Engineering1997，，1： | 1 |
| 14 | Assessmentof the prevalence of infection with Helicobacter pylori in patients with inflammatory bowel disease显示文摘 | Pearce CB Duncan HD Timmis L | 2000 | Eur J Gastroenterol Hepatol2000，12，4： | 1 |
| 15 | An artificial immune system for data analysis显示文摘 | Timmis J Mark Neal John Hunt | 2000 | BioSystems2000，，55： | 1 |
| 16 | Thermal gradient gel electrophoresis analysis of bioprotection from pollutant shocks in the activated sludge microbi al community显示文摘 | Eichner C A Erb R W Timmis K N | 1999 | Applied and Environmental Micro biology1999，65，： | 1 |
| 17 | A prospective randomized clinical trial of intracoronary streptokinase versus coronary angioplasty for acute myocardial infarction显示文摘 | O'Neill W Timmis GC Bourdillon PD | 1986 | N Engl J Med1986，，： | 1 |
| 18 | Artificial immune system for data analysis显示文摘 | Timmis J Neal T Hunt J | 2000 | Biosystems2000，55，13： | 1 |
| 19 | An Artifical Immune System for Data Analysis 显示文摘 | J Timmis M Neal J Hunt | 2000 | Biosystems2000，55，13： | 1 |
| 20 | Native-speaker norms and international English:A classroom view显示文摘 | Timmis I | | 0，，03： | 1 |
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