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| 1 | Rectal nitric oxide as biomarker in the treatment of inflammatory bowel disease: Responders versus nonresponders显示文摘瞄准:探索直肠的氮的氧化物(没有) 作为处理的简历标记,在 ulcerative (UC ) 和 Crohn 的反应是疾病(CD ) ,并且检验在之间的关系直肠没有,没有 synthases (NOS ) 的粘膜表示,和支持 inflammatory cytokines。方法:有 UC 的 22 个病人并且 24 在类固醇治疗期间与 CD 被监视。直肠没有层次被测量,临床的活动在天被估计 1, 3, 7 和 28。NOS 和支持 inflammatory cytokines 的粘膜存在被免疫组织化学和 RT-PCR 分析。结果:显著地显示的活跃 UC 和 CD 增加了直肠没有层次(10950 +/- 1280 每十亿分开的 7610 和 5040 +/-(ppb ) ,分别地) 作为与控制相比(154 +/- 71 ppb, P <
0.001 ) 。直肠不在 UC 和 CD 与疾病活动微弱地相关(r = 0.34 为 UC 和 r = 0.48 为 CD, P <
0.01 ) 。在 12 个病人,一堂类固醇倔强的功课导致了结肠切除术。仅仅稍微有的这些病人没增加层次(UC:620 +/- 270 ppb;CD:1260 +/- 550 ppb ) 与那些相比与治疗学的回答(UC:18860 +/- 530 ppb, P <
0.001;CD:10060 +/- 3200 ppb, P <
0.05 ) 。结论:直肠没有水平是在是的 IBD 的治疗反应的一个有用简历标记低没有层次预言差的临床的回答到类固醇治疗。 | Tryggve Ljung Sofie Lundberg Mark Varsanyi Catharina Johansson Peter T Schmidt Max Herulf Jon O Lundberg Per M Hellstr(o|¨)m | 2006 | World Journal of Gastroenterology2006，12，21： | 10 |
| 2 | Long-term prognosis in patients with severe late radiation enteropathy:A prospective cohort study显示文摘AIM: To assess persistent symptoms and mortality in a cohort of patients with severe (grade 3-4) radiation enteropathy,59 patients were followed up after 15-18 years. METHODS: Fifty-nine patients were prospectively enrolled by twelve surgical departments. Primary malignant disease,radiation therapy and surgical management were recorded at inclusion. The cause of death or persistence of symptoms was examined in public death records or by interview of survivors. RESULTS: Thirty-nine patients had received radiation therapy for gynaecological cancers,twelve for urological cancers,four for gastrointestinal cancers and four for other malignancies. Forty-five patients (76%) required surgical intervention. Complications occurred in 11 (25%) operated patients. Forty-seven patients had died at the time of follow-up,seven (12%) died as a direct result of radiation enteropathy,while radiation enteropathy contributed to death in an additional seven patients. Four of the twelve surviving patients suffered from chronic debilitating symptoms of radiation enteropathy,while three had moderate symptoms. CONCLUSION: Patients with severe delayed radiation enteropathy have a high risk of persistence of symptoms after surgery. At least one in ten patients dies from radiation-induced bowel injury. | Annette Larsen Jon B Reitan Steinar T Aase Martin Hauer-Jensen | 2007 | World Journal of Gastroenterology2007，13，26： | 4 |
| 3 | Targeting Dexamethasone to Macrophages in a Porcine Endotoxemic Model显示文摘 | Asger Granfeldt Christine Lodberg Hvas Jonas Heilskov Graversen Peter Astrup Christensen Mikkel Due Petersen Gabriela Anton Pia Svendsen Christoffer S?lling Anders Etzerodt Else T?nnesen S?ren Kragh Moestrup Holger Jon M?ller | 2013 | Critical Care Medicine2013，，11： | 2 |
| 4 | Vascular endothelial growth factor-D and its receptor VEGFR- 3 : two novel independent prognostic markers in gastric adenocarcinoma显示文摘 | JUTTNER S WISSMANN C JONS T | 2006 | J Clin Oncol2006，24，： | 1 |
| 5 | Two-stage and multi-splitting methods for the parallel solution of lienar system显示文摘 | SZYLD D B JONS M T | 1992 | SIAM J Matrix Annl Appl1992，13，2： | 1 |
| 6 | An experimental investigation of the electrostatic discharge (ESD) mechanism in packaged semiconductor devices显示文摘 | M C Jon T L Welsher | 1994 | J of Electrostatics1994，32，： | 1 |
| 7 | Vascular endothelial growth factor-D and its receptor VEGFR-3 : two novel independent prognostic markers in gastric adenocarcinoma 显示文摘 | Juttner S Wissmann C Jons T | 2006 | J Clin Oncol2006，24，： | 1 |
| 8 | Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson’s disease: an open-label, phase I trial显示文摘 | William J Marks Jill L Ostrem Leonard Verhagen Philip A Starr Paul S Larson Roy AE Bakay Robin Taylor Deborah A Cahn-Weiner A Jon Stoessl C Warren Olanow Raymond T Bartus | 2008 | Lancet Neurology2008，，5： | 1 |
| 9 | Sequential quadratic programming for large-scale nonlinear optimization显示文摘 | Boggs P T Jon W T | 1995 | Journal of Computational and Applied Mathematics1995，124，1： | 1 |
| 10 | Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice 显示文摘 | Bradlow H L Jon J Michnovicz Nitin T Telang | 1991 | Carcinogenesis1991，12，9： | 1 |
| 11 | How Does Charitable Giving Respond to Incentives And Income? New Estimates from Panel Date显示文摘 | Bakija Jon Heim B T | 2011 | National Tax Journal2011，，64： | 1 |
| 12 | Nitrate and nitrite in biology, nutrition and therapeutics显示文摘 | JON O L MARK T G AMRITA A | 2009 | Na- ture Chemical Biology2009，5，： | 1 |
| 13 | Recent advance in techniques for hyperspectral image processing显示文摘 | Antonio P Jon A B Joseph W B Jason B Lorenzo B Gustavo C V Jocelyn C Mathieu F Paolo G Anthony G Mattia M James C T Giovanna T | 2009 | Remote Sensing of Environment2009，113，： | 1 |
| 14 | Vascular endothelial growth factor-D and its receptor VEGFR-3: two novel independent prognosticmarkers in gastric adenocarcinoma 显示文摘 | Juttner S Wissmann C Jons T | 2006 | J Clin Oncol2006，24，2： | 1 |
| 15 | Contributions to Wavelength shifts of DFB fiber lasers used as acoustic sensors in air显示文摘 | Sigurd W L Kjell B Jon T K | 1998 | SPIE1998，3484，： | 1 |
| 16 | Application areas of AIS:the past,the present and the future显示文摘 | Emma H Jon T | 2008 | Applied Soft Computing(S1568-4946)2008，8，1： | 1 |
| 17 | An evaluation of three clustering procedures for use in synoptic classification显示文摘 | Guanri T Jon A S | 1987 | American Meteorological Society1987，26，5： | 1 |
| 18 | Vascular endothelial growth factor-D and its receptor VEGF-3:two novel independent prognostic markers in gastric adenocarcinoma显示文摘 | Juttner S Weismann C Jons T | 2006 | Clin Oncol2006，24，： | 1 |
| 19 | Vascular endothelial growth factor-D and its receptor VEGFR-3 : two novel independent prognostic markers in gastric adenocarcinoma显示文摘 | JUttner S Wissmann C Jons T | 2006 | J Ciin Oncol2006，24，2： | 1 |
| 20 | The production of fatty acid isopropyl esters and their use as a diesel engine fuel显示文摘 | PAUL S W MUSTAFA E T JON V G | 2005 | Journal of the American Oil Chemists'' Society2005，82，11： | 1 |
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