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11篇 您的检索式：作者名="Heilskov"

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		题名	作者	年代	出处	被引量
	1	Targeting Dexamethasone to Macrophages in a Porcine Endotoxemic Model显示文摘	Asger Granfeldt Christine Lodberg Hvas Jonas Heilskov Graversen Peter Astrup Christensen Mikkel Due Petersen Gabriela Anton Pia Svendsen Christoffer S?lling Anders Etzerodt Else T?nnesen S?ren Kragh Moestrup Holger Jon M?ller	2013	Critical Care Medicine2013，，11：	2
	2	Late endophthalmitis after transscleral fixation of a posterior chamber intraocular lens (letter)显示文摘	Joondeph BC Olsen KR Blankenship GW	1989	Arch Ophthalmol1989，107，：	1
	3	Modeling of aerodynamically generated noise from wind tur- bines显示文摘	Zhu W J Heilskov N Shen W Z	2005	Journal of Solar Energy Engineering2005，127，4：	1
	4	Technological advances in cold phacoemulsification cataract & refractive surgery today显示文摘	David C Heilskov T Kangas TA Feist RM	2002	J Cataract Refract Surg2002，28，：	1
	5	Effects of benthic fauna on organic matter mineralization in fish-farm sediments : Importance of size and abundance 显示文摘	HEILSKOV A C HOLMER M	2001	ICES Journal of Marine Science2001，58，：	1
	6	Late endophthalmitis after transscleral fixation of a posterior chamber intraocular lens 显示文摘	Heilskov T Joondeph BC Olsen KR	1989	Arch Ophthalmol1989，107，10：	1
	7	Modeling of aerodynamically generated noise from wind turbines显示文摘	ZHU W J HEILSKOV N SHEN W Z		Journal of Solar Energy Engineering0，127，：	1
	8	Anti-CD163-dexamethasone conjugate inhibits the acute phase response to lipopolysaccharide in rats显示文摘AIM: To study the effect of a new anti-CD163-dexamethasone conjugate targeting activated macrophages on the hepatic acute phase response in rats. METHODS: Wistar rats were injected intravenous with either the CD163 targeted dexamethasone-conjugate(0.02 mg/kg) or free dexamethasone(0.02 or 1 mg/kg) 24 h prior to lipopolysaccharide(LPS)(2.5 mg/kg intraperitoneal). We measured plasma concentrations of tumour necrosis factor-a(TNF-a) and interleukin 6(IL-6) 2 h post-LPS and liver m RNAs and serum concentrations of the rat acute phase protein a-2-macroglobulin(a-2-M) 24 h after LPS. Also, plasma concentrations of alanine aminotransferase and bilirubin were measured at termination of the study. Spleen weight served as an indicator of systemic steroid effects.RESULTS: The conjugate halved the a-2-M liver m RNA(3.3 ± 0.6 vs 6.8 ± 1.1, P < 0.01) and serum protein(201 ± 48 μg/mL vs 389 ± 67 μg/mL, P = 0.04) after LPS compared to low dose dexamethasone treated animals, while none of the free dexamethasone doses had an effect on liver m RNA or serum levels of a-2-M. Also, the conjugate reduced TNF-a(7208 ± 1977 pg/mL vs 21583 ± 7117 pg/mL, P = 0.03) and IL-6(15685 ± 3779 pg/mL vs 25715 ± 4036 pg/mL, P = 0.03) compared to the low dose dexamethasone. The high dose dexamethasone dose decreased the spleen weight(421 ± 11 mg vs 465 ± 12 mg, P < 0.05) compared to controls, an effect not seen in any other group.CONCLUSION: Low-dose anti-CD163-dexamethasone conjugate effectively decreased the hepatic acute phase response to LPS. This indicates an anti-inflammatory potential of the conjugate in vivo.	Karen Louise Thomsen Holger Jon Moller Jonas Heilskov Graversen Nils E Magnusson Soren K Moestrup Hendrik Vilstrup Henning Gronbaek	2016	World Journal of Hepatology2016，8，17：	1
	9	Modeling of aerodynamically generated noise from wind turbines显示文摘	Zhu Weijun Heilskov Nicolai Shen Wenzhong		0，，04：	1
	10	Modeling of Aerodynamically Generated Noise from Wind Turbines显示文摘	Zhu Weijun Heilskov N Shen Wenzhong	2005	Jouranl of Solar Energy Engineering2005，127，4：	1
	11	Benthic fauna bio-irrigation effects on nutrient regeneration in fish farm sediments显示文摘	Anna C Heilskov A Marc A	2006	J Experim Mar Biol Ecol2006，339，：	1

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