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| 1 | In vitro and in vivo biodegradation and biocompatibility of an MMT/BSA composite coating upon magnesium alloy AZ31显示文摘The performance of biodegradable magnesium alloy requires special attention to rapid degradation and poor biocompatibility, which can cause the implant to fail. Here, a sodium montmorillonite(MMT)/bovine serum albumin(BSA) composite coating was prepared upon magnesium alloy AZ31 via hydrothermal synthesis, followed by dip coating. We evaluated the surface characterization and corrosion behavior in vitro, and the biocompatibility in vitro and in vivo. Biodegradation progress of the MMT-BSA coated Mg pieces was examined through hydrogen evolution, immersion tests, and electrochemical measurements in Hank’s solution. In vitro biocompatibility studies were evaluated via hemolysis tests, dynamic cruor time tests, platelet adhesion, MTT testing and live-dead stain of osteoblast cells(MC3 T3-E1). It was found that the MMT-BSA coating had good corrosion resistance and a marked improvement in biocompatibility in comparison to bare Mg alloy AZ31. in vivo studies were carried out in rat model and the degradation was characterized by computed tomography scans. Results revealed that the MMT-BSA coated Mg alloy AZ31 implants maintained their structural integrity and slight degradation after 120 d of post-implantation. A100% survival rate for the rats was observed with no obvious toxic damages on the organs and tissues.Additionally, we proposed a sound coating formation mechanism. Considering the good corrosion protection and biocompatibility, the MMT-BSA coated Mg alloy AZ31 is a promising candidate material for biomedical implants. | Jian Wang Lanyue Cui Yande Ren Yuhong Zou Jinlong Ma Chengjian Wang Zhongyin Zheng Xiaobo Chen Rongchang Zeng Yufeng Zheng | 2020 | Journal of Materials Science & Technology2020，47，12： | 7 |
| 2 | The RNA-binding protein Musashi2 governs osteoblast-adipocyte lineage commitment by suppressing PPARγsignaling显示文摘Osteoporosis caused by aging is characterized by reduced bone mass and accumulated adipocytes in the bone marrow cavity. How the balance between osteoblastogenesis and adipogenesis from bone marrow mesenchymal stem cells(BMSCs) is lost upon aging is still unclear. Here, we found that the RNA-binding protein Musashi2(Msi2) regulates BMSC lineage commitment. Msi2 is commonly enriched in stem cells and tumor cells. We found that its expression was downregulated during adipogenic differentiation and upregulated during osteogenic differentiation of BMSCs. Msi2 knockout mice exhibited decreased bone mass with substantial accumulation of marrow adipocytes, similar to aging-induced osteoporosis. Depletion of Msi2 in BMSCs led to increased adipocyte commitment. Transcriptional profiling analysis revealed that Msi2 deficiency led to increased PPARγ signaling.RNA-interacting protein immunoprecipitation assays demonstrated that Msi2 could inhibit the translation of the key adipogenic factor Cebpα, thereby inhibiting PPAR signaling. Furthermore, the expression of Msi2 decreased significantly during the aging process of mice, indicating that decreased Msi2 function during aging contributes to abnormal accumulation of adipocytes in bone marrow and osteoporosis. Thus, our results provide a putative biochemical mechanism for aging-related osteoporosis, suggesting that modulating Msi2 function may benefit the treatment of bone aging. | Jinlong Suo Sihai Zou Jinghui Wang Yujiao Han Lingli Zhang Chenchen Lv Bo Jiang Qian Ren Long Chen Lele Yang Ping Ji Xianyou Zheng Ping Hu Weiguo Zou | 2022 | Bone Research2022，10，3： | 5 |
| 3 | Mode and modulation characteristics for microsquare lasers with a vertex output waveguide显示文摘The mode and high-speed modulation characteristics are investigated for a microsquare laser with a side length of 16 ?m and a 2-?m-wide output waveguide connected to one vertex. The longitudinal and transverse mode characteristics are analyzed by numerical simulation and light ray model, and compared with the lasing spectra for the microsquare laser. Up to the fifth transverse mode is observed clearly from the lasing spectra. Single mode operation with the side mode suppression ratio of 41 d B is realized at the injection current of 24 m A, and the maximum output power of 0.53(0.18) m W coupled into the multiple(single) mode fiber is obtained at the current of 35 m A, for the microsquare laser at the temperature of 288 K. Furthermore, a flat small-signal modulation response is reached with the 3-d B bandwidth of 16.2 GHz and the resonant peak of 3.6 d B at the bias current of 34 m A. The K-factor of 0.22 ns is obtained by fitting the damping factor versus the resonant frequency, which implies a maximum intrinsic 3-d B bandwidth of 40 GHz. | LONG Heng HUANG YongZhen YANG YueDe ZOU LingXiu XIAO JinLong XIAO ZhiXiong | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，11： | 4 |
| 4 | Assimilation of MODIS-LAI into the WOFOST model for forecasting regional winter wheat yield显示文摘 | Guannan Ma Jianxi Huang Wenbin Wu Jinlong Fan Jinqiu Zou Sijie Wu | 2013 | Mathematical and Computer Modelling . 2013 (3-4)2013，，3： | 1 |
| 5 | Ceramsite made with water and wastewater sludge and its characteristics affected by SiO2 and A1203显示文摘 | Guoren Xu Jinlong Zou Guibai Li | 2008 | Environmental Science and Technology2008，42，19： | 1 |
| 6 | Utilization of dried sludge for making ceramsite显示文摘 | XU Guoren ZOU Jinlong DAI Yun | 2006 | Water Science and Technolegy2006，54，9： | 1 |
| 7 | Ceramsite made with water and wastewater sludge and its characteristics affected by SiO2 and A12O3 显示文摘 | Xu Guoren Zou Jinlong Li Guibai | 2008 | Environ Sci Techn2008，42，19： | 1 |
| 8 | Assimilation of MODIS-LAI into the WOFOST model for forecasting regional winter wheat yield显示文摘 | Guannan Ma Jianxi Huang Wenbin Wu Jinlong Fan Jinqiu Zou Sijie Wu | 2013 | Mathematical and Computer Modelling (-)2013，，3： | 1 |
| 9 | Nitrogen removal and biofilm structure affected by COD/NH4+-N in a biofilter with porous sludge-ceramsite显示文摘 | Zou Jinlong Xu Guoren Pan Kai | 2012 | Separation and Purification Technology2012，94，： | 1 |
| 10 | Ceramsite obtained from water and wastewater sludge and its characteristics affected by (FezO3 + CaOq-Naz O/SiOz q-Alz O3 ) 显示文摘 | Xu Guoren Zou Jinlong Li Guibai | 2009 | J Hazard Mater2009，165，1： | 1 |
| 11 | Electron-ion collider in China显示文摘Lepton scattering is an established ideal tool for studying inner structure of small particles such as nucleons as well as nuclei.As a future high energy nuclear physics project,an Electron-ion collider in China(EicC)has been proposed.It will be constructed based on an upgraded heavy-ion accelerator,High Intensity heavy-ion Accelerator Facility(HIAF)which is currently under construction,together with a new electron ring.The proposed collider will provide highly polarized electrons(with a po-larization of 80%)and protons(with a polarization of 70%)with variable center of mass energies from 15 to 20 GeV and the luminosity of(2–3)×1033 cm^(−2)·s^(−1).Polarized deuterons and Helium-3,as well as unpolarized ion beams from Carbon to Uranium,will be also available at the EicC.The main foci of the EicC will be precision measurements of the structure of the nucleon in the sea quark region,including 3D tomography of nucleon;the partonic structure of nuclei and the parton interaction with the nuclear environment;the exotic states,especially those with heavy flavor quark contents.In addition,issues fundamental to understanding the origin of mass could be addressed by measurements of heavy quarkonia near-threshold production at the EicC.In order to achieve the above-mentioned physics goals,a hermetical detector system will be constructed with cutting-edge technologies.This document is the result of collective contributions and valuable inputs from experts across the globe.The EicC physics program complements the ongoing scientific programs at the Jefferson Laboratory and the future EIC project in the United States.The success of this project will also advance both nuclear and particle physics as well as accelerator and detector technology in China. | Daniele PAnderle Valerio Bertone Xu Cao Lei Chang Ningbo Chang Gu Chen Xurong Chen Zhuojun Chen Zhufang Cui Lingyun Dai Weitian Deng Minghui Ding Xu Feng Chang Gong Longcheng Gui Feng-Kun Guo Chengdong Han Jun He Tie-Jiun Hou Hongxia Huang Yin Huang KrešImir KumeričKi LPKaptari Demin Li Hengne Li Minxiang Li Xueqian Li Yutie Liang Zuotang Liang Chen Liu Chuan Liu Guoming Liu Jie Liu Liuming Liu Xiang Liu Tianbo Liu Xiaofeng Luo Zhun Lyu Boqiang Ma Fu Ma Jianping Ma Yugang Ma Lijun Mao Cédric Mezrag HervéMoutarde Jialun Ping Sixue Qin Hang Ren Craig DRoberts Juan Rojo Guodong Shen Chao Shi Qintao Song Hao Sun PawełSznajder Enke Wang Fan Wang Qian Wang Rong Wang Ruiru Wang Taofeng Wang Wei Wang Xiaoyu Wang Xiaoyun Wang Jiajun Wu Xinggang Wu Lei Xia Bowen Xiao Guoqing Xiao Ju-Jun Xie Yaping Xie Hongxi Xing Hushan Xu Nu Xu Shusheng Xu Mengshi Yan Wenbiao Yan Wencheng Yan Xinhu Yan Jiancheng Yang Yi-Bo Yang Zhi Yang Deliang Yao Zhihong Ye Peilin Yin C-PYuan Wenlong Zhan Jianhui Zhang Jinlong Zhang Pengming Zhang Yifei Zhang Chao-Hsi Chang Zhenyu Zhang Hongwei Zhao Kuang-Ta Chao Qiang Zhao Yuxiang Zhao Zhengguo Zhao Liang Zheng Jian Zhou Xiang Zhou Xiaorong Zhou Bingsong Zou Liping Zou | 2021 | Frontiers of physics2021，16，6： | 1 |
| 12 | In situ resource utilization of lunar soil for highly efficient extraterrestrial fuel and oxygen supply显示文摘Building up a lunar settlement is the ultimate aim of lunar exploitation.Yet,limited fuel and oxygen supplies restrict human survival on the Moon.Herein,we demonstrate the in situ resource utilization of lunar soil for extraterrestrial fuel and oxygen production,which may power up our solely natural satellite and supply respiratory gas.Specifically,the lunar soil is loaded with Cu species and employed for electro catalytic CO_(2)conversion,demonstrating significant production of methane.In addition,the selected component in lunar soil(i.e.MgSiO_(3))loaded with Cu can reach a CH_(4)F aradaic efficiency of 72.05% with a CH_(4)production rate of 0.8 mL/min at 600 mA/cm^(2).Simultaneously,an O_(2)production rate of 2.3 mL/min can be achieved.Furthermore,we demonstrate that our developed process starting from catalyst preparation to electrocatalytic CO_(2)conversion is so accessible that it can be operated in an unmmaned manner via a robotic system.Such a highly efficient extraterrestrial fuel and oxygen production system is expected to push forward the development of mankind’s civilization toward an extraterrestrial settlement. | Yuan Zhong Jingxiang Low Qing Zhu Yawen Jiang Xiwen Yu Xinyu Wang Fei Zhang Weiwei Shang Ran Long Yingfang Yao Wei Yao Jun Jiang Yi Luo Weihua Wang Jinlong Yang Zhigang Zou Yujie Xiong | 2023 | National Science Review2023，10，2： | 1 |
| 13 | Premature aging of skeletal stem/progenitor cells rather than osteoblasts causes bone loss with decreased mechanosensation显示文摘A distinct population of skeletal stem/progenitor cells(SSPCs)has been identified that is indispensable for the maintenance and remodeling of the adult skeleton.However,the cell types that are responsible for age-related bone loss and the characteristic changes in these cells during aging remain to be determined.Here,we established models of premature aging by conditional depletion of Zmpste24(Z24)in mice and found that Prx1-dependent Z24 deletion,but not Osx-dependent Z24 deletion,caused significant bone loss.However,Acan-associated Z24 depletion caused only trabecular bone loss.Single-cell RNA sequencing(sc RNA-seq)revealed that two populations of SSPCs,one that differentiates into trabecular bone cells and another that differentiates into cortical bone cells,were significantly decreased in Prx1-Cre;Z24^(f/f)mice.Both premature SSPC populations exhibited apoptotic signaling pathway activation and decreased mechanosensation.Physical exercise reversed the effects of Z24depletion on cellular apoptosis,extracellular matrix expression and bone mass.This study identified two populations of SSPCs that are responsible for premature aging-related bone loss.The impairment of mechanosensation in Z24-deficient SSPCs provides new insight into how physical exercise can be used to prevent bone aging. | Ruici Yang Dandan Cao Jinlong Suo Lingli Zhang Chunyang Mo Miaomiao Wang Ningning Niu Rui Yue Weiguo Zou | 2023 | Bone Research2023，11，3： | 0 |
| 14 | Effects of fluorination on crystal structure and electrochemical performance of antiperovskite solid electrolytes显示文摘The development of all-solid-state lithium batteries(ASSLBs)depends on exploiting solid-state electrolytes(SSEs)with high ionic conductivity and electrochemical stability.Fluorination is generally considered to be an effective strategy to improve the ionic conductivity and electrochemical stability of inorganic SSEs.Here,we report the partial fluorination of the chlo rine sites in an antiperovskite,by which the orthorhombic Li_(2)OHCl was transformed into cubic Li_(2)OHCl_(0.9)F_(0.1),resulting in a fourfold increase in ionic conductivity at 30℃.The ab initio molecular dynamics simulations suggest that both the crystal symmetry and the anions electronegativity influence the diffusion of Li+in the antiperovskite structure.Besides,from the perspective of experiments and calculations,it is confirmed that fluorination is a feasible method to improve the electrochemical stability of antiperovskite SSEs.The LiFePO_(4)|Li cell based on Li_(2)OHCl_(0.9)F_(0.1) is also assembled and exhibits stable cycle performance,which indicates that fluorination of antiperovskite SSEs is an effective way to produce high-performance SSEs for practical application of ASSLBs. | Lei Gao Manrong Song Ruo Zhao Songbai Han Jinlong Zhu Wei Xia Juncao Bian Liping Wang Song Gao Yonggang Wang Ruqiang Zou Yusheng Zhao | 2023 | Journal of Energy Chemistry2023，，2： | 0 |
| 15 | Acid-Stable CoWO_(4)/WO_(3)-Microrod Coated by a Thin Carbon-Layer as Efficient Pt Co-Catalysts for Methanol Oxidation and Oxygen Reduction显示文摘Insufficient activity and instability(poisoning)of Pt-based electrocatalysts for methanol oxidation and oxygen reduction reactions(MOR/ORR)impede the development of direct methanol fuel cells.Here,CoWO_(4) nanoparticles-loaded WO_(3) microrods coated by a thin carbon-layer are used as Pt-supports/co-catalysts for MOR/ORR.WO_(3) grows along the(110)crystal plane to form microrod(diameter of~0.6 um),which is coated by a carbon-layer(~5 nm).Pt-CoWO_(4)/WO_(3)@NCL-mr(850℃)shows a higher mass activity(2208 mA mg^(-1)_(pt))than the commercial Pt/C(659.4 mA mg^(-1)_(pt)).CoWO_(4)/WO_(3) heterojunction on the microrod surface with abundant oxygen vacancies allows the generation of surface-adsorbed hydroxyl to facilitate CO elimination and regeneration of the occupied Pt active-sites(promising stability).PtCo WO_(4)/WO_(3)@NCL-mr(850℃)has higher half-wave(0.46 V)and onset(0.54 V)potentials than Pt/C(0.41 and 0.50 V)for ORR.The microrod structure of Co WO_(4)/WO_(3)@NCL facilitates the dispersibility of Pt NPs to increase the utilization of Pt active sites and relieve the self-aggregation of Pt to obtain a promising synergy between Pt and CoWO_(4)(Co^(2+))for ORR in acid media.This study provides insights not only into the synthesis of acid-resistant WO_(3)@NCL microrod as active Pt co-catalyst,but also into the effective utilization of surface oxygen vacancies and Co^(2+) for MOR/ORR. | Jiahuan Li Jiahao Xie Xinyu Wang Ying Dai Xiaoqin Xu Jin Liu Zhuang Cai Xin Meng Jinlong Zou | 2022 | Chinese Journal of Structural Chemistry2022，41，7： | 0 |
| 16 | Application of neutron imaging in observing various states of matter inside lithium batteries显示文摘Lithium batteries have been essential technologies and become an integral part of our daily lives,powering a range of devices from phones to electric vehicles.To fully understand and optimize the performance of lithium batteries,it is necessary to investigate their internal states and processes through various characterization methods.Neutron imaging has been an indispensable complementary characterization technique to X-ray imaging or electron microscopy because of the unique interaction principle between neutrons and matter.It provides particular insights into the various states of matter inside lithium batteries,including the Li+concentration in solid electrodes,the Li plating/stripping behavior of Li-metal anodes,the Li+diffusion in solid ionic conductors,the distribution of liquid electrolytes and the generation of gases.This review aims to highlight the capabilities and advantages of neutron imaging in characterizing lithium batteries,as well as its current state of application in this field.Additionally,we discuss the potential of neutron imaging to contribute to the ongoing development of advanced batteries through its ability to visualize internal evolution. | Lei Gao Songbai Han Haijin Ni Jinlong Zhu Liping Wang Song Gao Yonggang Wang Dubin Huang Yusheng Zhao Ruqiang Zou | 2023 | National Science Review2023，10，11： | 0 |
| 17 | A Research on the 2014 Wenzhou M4.2 Earthquake in the Shanxi Reservoir显示文摘Complete records of more than 3,000 earthquake events in the Shanxi, Wenzhou reservoir earthquake sequence were recorded from August to November,2014 by the high-density,high-resolution monitoring stations of the Zhejiang Regional Digital Seismic Network and the reservoir earthquake monitoring network,with a maximum magnitude of M4. 2. Based on 3-D epicenter location, focal mechanism solutions, and in combination with the geological and tectonic characteristics of the reservoir area,the earthquake sequence is discussed in this paper. The linear fitting of the Hypo SAT location results show that the main shock occurred in the NW trending fault and the earthquake sequence is concentrated in bands along the active faults,with a strike of305 °,dipping SW with dip angle of 85 °. By using P-wave first motion symbols, we obtained the average focal mechanism of M ≥ 3. 5 earthquakes,with a strike 308 ° and dip 84 ° for nodal plane II. The field geological survey and research show that the strike,dip and rake of nodal plane II are roughly consistent with the occurrence of the Shuangxi-Jiaoxi fault. The comprehensive analysis reveals that the NW-trending Shuangxi-Jiaoxi fault is the seismogenic structure of the earthquakes. | Zou Zhenxuan Ma Zhijiang Zhou Xinmin Zhang Fan Li Jun Li Jinlong | 2017 | Earthquake Research in China2017，31，4： | 0 |
| 18 | Single-Cu-atoms anchored on 3D macro-porous carbon matrix as efficient catalyst for oxygen reduction and Pt co-catalyst for methanol oxidation显示文摘Single metal atoms immobilized on a carbon substrate are of great potential for enhancing the catalytic activities for oxygen reduction and methanol oxidation reactions(ORR/MOR)owing to the maximized atom utilization.Herein,single copper atoms(SCAs)are loaded on macro-porous nitrogen-doped carbon(Cu-NC)derived from zeolitic imidazolate framework-8(ZIF-8),which are used as catalysts for ORR and Pt-supports for MOR.For ORR,the catalyst marked as Cu-NC-3 exhibits a higher peak potential of 0.87 V(vs.Reversible hydrogen electrode)than that of commercial Pt/C(0.83 V),mainly attributing to that the 3D macro-porous structure of Cu-NC-3 provides adequate space for uniform dispersion of SCAs as the main active species,and smooth diffusion pathways for fast transport of substances(O_(2),H_(2)O),therefore reducing the overpotential and the intermediate(H_(2)O_(2))generation to enhance ORR activity.For MOR,Pt-Cu-NC-3 has a higher mass activity of 1217.4 mA/mg Pt than that of Pt/C(752.4 mA/mg Pt),and its activity maintenance(decline of 27.6%)is also better than Pt/C(decline of 44.0%)after 5000 cyclic voltammetry(CV)cycles.The interactions between SCAs and Pt nanoparticles should facilitate the generation of OH−from water molecules,which can fast eliminate the adsorbed CO to recover the Pt active sites to improve MOR performance.This synthesis strategy affords a new inspiration to prepare single metal atoms loaded on ZIFs-derived macro-structure with diverse activities for ORR/MOR. | Jin Ma Bin Liu Rongyue Wang Zhiyao Sun Ying Zhang Yubo Sun Zhuang Cai Yao Li Jinlong Zou | 2022 | Chinese Chemical Letters2022，33，5： | 0 |
| 19 | A custom-designed panel sequencing study in 201 Chinese patients with craniosynostosis revealed novel variants and distinct mutation spectra显示文摘Craniosynostosis is a rare disease in which one or more of the cranial sutures in an infant skull prematurely fuses by turning into bone,with a prevalence of 1 in 2,000—2,500 individuals from reports in Western countries(Wilkie et al.,2017).It may restrict the growth of the brain,leading to some degree of morphological and functional abnormalities,and may affect the neurocognitive function of infants(Lattanzi et al.,2017).Genetic variants underlying craniosynostosis have been identified in cohort studies in Western populations. | Yingzhi Wu Meifang Peng Jieyi Chen Jinlong Suo Sihai Zou Yanqing Xu Andrew O.M.Wilkie Weiguo Zou Xiongzheng Mu Sijia Wang | 2021 | Journal of Genetics and Genomics2021，48，2： | 0 |
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