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| 1 | Upconversion 32Nb_(2)O_(5)-10La_(2)O_(3)-16ZrO_(2) glass activated with Er^(3+)/Yb^(3+) and dye sensitized solar cell application显示文摘Er^(3+)/Yb^(3+)codoped niobium pentoxide glasses were fabricated by the aerodynamic levitation(ADL)method with rapid cooling rate.All samples with various doping concentrations showed good upconversion luminescence properties under 980 nm laser excitation.The structure,transmittance spectrum,and luminescence properties of the samples were systemically investigated by XRD,UV-Vis-NIR spectrophotometer,and upconversion spectra.All transparent samples exhibited green and red upconversion emissions centered at 532,547,and 670 nm.Experimental results showed that the sample codoped with 1 mol%Er^(3+)/Yb^(3+)has the strongest upconversion emissions,and the increase of the doped Yb^(3+)concentration results in the increased red emission and reduced green emission.The logI-logP plot of green emission indicated that the green emissions reach the saturation at high pump power excitation,deviating from the low-power regime.After one-photon energy transfer(ET)process,^(4)I_(11/2)+^(4)I_(11/2)→^(4)F_(7/2)+^(4)I_(15/2) process between the two neighboring Er^(3+)ions was responsible for the population of the 4S3/2/4H11/2 states.The niobium pentoxide codoped with Er^(3+)/Yb^(3+)bulk glasses could be used in the dye sensitized solar cell(DSSC)to improve the efficiency. | Xiaoyu LI Jiaying LI Jianqiang LI Hong LIN Bo LI | 2017 | Journal of Advanced Ceramics2017，6，4： | 4 |
| 2 | Thymosin Alpha-1 Inhibits Complete Freund’s Adjuvant-Induced Pain and Production of Microglia-Mediated Pro-inflammatory Cytokines in Spinal Cord显示文摘Activation of inflammatory responses regulates the transmission of pain pathways through an integrated network in the peripheral and central nervous systems.The immunopotentiator thymosin alpha-1(Tal)has recently been reported to have anti-inflammatory and neuroprotective functions in rodents.However,how Tα1 affects inflammatory pain remains unclear.In the present study,intraperitoneal injection of Tal attenuated complete Freund's adjuvant(CFA)-induced pain hypersensitivity,and decreased the up-regulation of pro-inflammatory cytokines(TNF-α,IL-1β,and IL-6)in inflamed skin and the spinal cord.We found that CFA-induced peripheral inflammation evoked strong microglial activation,but the effect was reversed by Tα1.Notably,Tα1 reversed the CFA-induced up-regulation of vesicular glutamate transporter(VGLUT)and down-regulated the vesicular γ-aminobutyric acid transporter(VGAT)in the spinal cord.Taken together,these results suggest that Tα1 plays a therapeutic role in inflammatory pain and in the modulation of microgliainduced pro-inflammatory cytokine production in addition to mediation of VGLUT and VGAT expression in the spinal cord. | Yunlong Xu Yanjun Jiang Lin Wang Jiahua Huang Junmao Wen Hang Lv Xiaoli Wu Chaofan Wan Chuanxin Yu Wenjie Zhang Jiaying Zhao Yinqi Zhou Yongjun Chen | 2019 | Neuroscience Bulletin2019，35，4： | 4 |
| 3 | Characterization of SARS-CoV-2 worldwide transmission based on evolutionary dynamics and specific viral mutations in the spike protein显示文摘Background:The coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome-related coronavirus-2(SARS-CoV-2)is pandemic.However,the origins and global transmission pattern of SARS-CoV-2 remain largely unknown.We aimed to characterize the origination and transmission of SARS-CoV-2 based on evolutionary dynamics.Methods:Using the full-length sequences of SARS-CoV-2 with intact geographic,demographic,and temporal information worldwide from the GISAID database during 26 December 2019 and 30 November 2020,we constructed the transmission tree to depict the evolutionary process by the R package'outbreaker'.The affinity of the mutated receptor-binding region of the spike protein to angiotensin-converting enzyme 2(ACE2)was predicted using mCSM-PPI2 software.Viral infectivity and antigenicity were tested in ACE2-transfected HEK293T cells by pseudovirus transfection and neutralizing antibody test.Results:From 26 December 2019 to 8 March 2020,early stage of the COVID-19 pandemic,SARS-CoV-2 strains identified worldwide were mainly composed of three clusters:the Europe-based cluster including two USA-based subclusters;the Asia-based cluster including isolates in China,Japan,the USA,Singapore,Australia,Malaysia,and Italy;and the USA-based cluster.The SARS-CoV-2 strains identified in the USA formed four independent clades while those identified in China formed one clade.After 8 March 2020,the clusters of SARS-CoV-2 strains tended to be independent and became'pure'in each of the major countries.Twenty-two of 60 mutations in the receptor-binding domain of the spike protein were predicted to increase the binding affinity of SARS-CoV-2 to ACE2.Of all predicted mutants,the number of E484K was the largest one with 86585 sequences,followed by S477N with 55442 sequences worldwide.In more than ten countries,the frequencies of the isolates with E484K and S477N increased significantly.V367F and N354D mutations increased the infectivity of SARS-CoV-2 pseudoviruses(P<0.001).SARS-CoV-2 with V367F was more sensitive to the S1-targeting neutralizing antibody than the wild-type counterpart(P<0.001).Conclusions:SARS-CoV-2 strains might have originated in several countries simultaneously under certain evolutionary pressure.Travel restrictions might cause location-specific SARS-CoV-2 clustering.The SARS-CoV-2 evolution appears to facilitate its transmission via altering the affinity to ACE2 or immune evasion. | Jiluo Liu Xi Chen Yan Liu Jiansheng Lin Jiaying Shen Hongwei Zhang Jianhua Yin Rui Pu Yibo Ding Guangwen Cao | 2021 | Infectious Diseases of Poverty2021，10，4： | 2 |
| 4 | Comparing dark-and photo-Fenton-like degradation of emerging pollutant over photo-switchable Bi2WO6/CuFe2O4: Investigation on dominant reactive oxidation species显示文摘The extensive use of tetracycline hydrochloride(TCH)poses a threat to human health and the aquatic environment.Here,magnetic p-n Bi2WO6/CuFe2O4 catalyst was fabricated to efficiently remove TCH.The obtained Bi2WO6/CuFe2O4 exhibited 92.1%TCH degradation efficiency and 50.7%and 35.1%mineralization performance for TCH and raw secondary effluent from a wastewater treatment plant in a photo-Fenton-like system,respectively.The remarkable performance was attributed to the fact that photogenerated electrons accelerated the Fe(III)/Fe(II)and Cu(II)/Cu(I)conversion for the Fenton-like reaction between Fe(II)/Cu(I)and H2O2,thereby generating abundant·OH for pollutant oxidation.Various environmental factors including H2O2 concentration,initial pH,catalyst dosage,TCH concentration and inorganic ions were explored.The reactive oxidation species(ROS)quenching results and electron spin resonance(ESR)spectra confirmed that·O2-and·OH were responsible for the dark and photo-Fenton-like systems,respectively.The degradation mechanisms and pathways of TCH were proposed,and the toxicity of products was evaluated.This work contributes a highly efficient and environmentally friendly catalyst and provides a clear mechanistic explanation for the removal of antibiotic pollutants in environmental remediation. | Jingjing Jiang Jiaying Gao Shu Niu Xingyue Wang Tianren Li Shengda Liu Yanhong Lin Tengfeng Xie Shuangshi Dong | 2021 | Journal of Environmental Sciences2021，33，8： | 1 |
| 5 | Virus-inspired surface-nanoengineered antimicrobial liposome:A potential system to simultaneously achieve high activity and selectivity显示文摘Enveloped viruses such as SARS-CoV-2 frequently have a highly infectious nature and are considered effective natural delivery systems exhibiting high efficiency and specificity.Since simultaneously enhancing the activity and selectivity of lipopeptides is a seemingly unsolvable problem for conventional chemistry and pharmaceutical approaches,we present a biomimetic strategy to construct lipopeptide-based mimics of viral architectures and infections to enhance their antimicrobial efficacy while avoiding side effects.Herein,a surface-nanoengineered antimicrobial liposome(SNAL)is developed with the morphological features of enveloped viruses,including a moderate size range,lipid-based membrane structure,and highly lipopeptide-enriched bilayer surface.The SNAL possesses virus-like infection to bacterial cells,which can mediate high-efficiency and high-selectivity bacteria binding,rapidly attack and invade bacteria via plasma membrane fusion pathway,and induce a local“burst”release of lipopeptide to produce irreversible damage of cell membrane.Remarkably,viral mimics are effective against multiple pathogens with low minimum inhibitory concentrations(1.6-6.3μg mL1),high bactericidal efficiency of>99%within 2 h,>10-fold enhanced selectivity over free lipopeptide,99.8%reduction in skin MRSA load after a single treatment,and negligible toxicity.This bioinspired design has significant potential to enhance the therapeutic efficacy of lipopeptides and may create new opportunities for designing next-generation antimicrobials. | Yin Shi Xiaoqian Feng Liming Lin Jing Wang Jiaying Chi Biyuan Wu Guilin Zhou Feiyuan Yu Qian Xu Daojun Liu Guilan Quan Chao Lu Xin Pan Jianfeng Cai Chuanbin Wu | 2021 | Bioactive Materials2021，6，10： | 1 |
| 6 | Effects of simulated rainfall events on soil carbon trans- formation显示文摘 | Zhang Jiaying Lin Zhongbin Zhang Renduo | 2010 | Australian Journal of Soil Research2010，48，5： | 1 |
| 7 | Tetrahedral DNA nanostructures synergize with MnO_(2) to enhance antitumor immunity via promoting STING activation and M1 polarization显示文摘Stimulator of interferon genes(STING) is a cytosolic DNA sensor which is regarded as a potential target for antitumor immunotherapy. However, clinical trials of STING agonists display limited anti-tumor effects and dose-dependent side-effects like inflammatory damage and cell toxicity. Here,we showed that tetrahedral DNA nanostructures(TDNs) actively enter macrophages to promote STING activation and M1 polarization in a size-dependent manner, and synergized with Mn^(2+) to enhance the expressions of IFN-β and iNOS, as well as the co-stimulatory molecules for antigen presentation. Moreover, to reduce the cytotoxicity of Mn^(2+),we constructed a TDN-MnO_(2) complex and found that it displayed a much higher efficacy than TDN plus Mn^(2+) to initiate macrophage activation and anti-tumor response both in vitro and in vivo. Together, our studies explored a novel immune activation effect of TDN in cancer therapy and its synergistic therapeutic outcomes with MnO_(2).These findings provide new therapeutic opportunities for cancer therapy. | Siping Liang Jiaying Li Zhengyu Zou Miao Mao Siqi Ming Fan Lin Ziyan Zhang Can Cao Jinyu Zhou Yuanqing Zhang Jiaping Li Minhao Wu | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 1 |
| 8 | Ginsenoside Rg1 protection against β-amyloid peptide-induced neuronal apoptosis via estrogen receptor α and glucocorticoid receptor-dependent anti-protein nitration pathway显示文摘 | Jiaying Wu Zongfu Pan Zhiqiang Wang Wenjie Zhu Yuanyuan Shen Rong Cui Jiazhen Lin Hao Yu Qiongque Wang Jianchang Qian Yongping Yu Danyan Zhu Yijia Lou | 2012 | Neuropharmacology2012，，3： | 1 |
| 9 | Facile synthesis of KVPO_(4)F/reduced graphene oxide hybrid as a high-performance cathode material for potassium-ion batteries显示文摘Potassium-ion batteries(PIBs) as a substitute for lithium-ion batteries have aroused widespread attention and have been rapidly developed. In the positive electrode materials, polyanionic compound has a high working voltage and large reversible capacity on account of its distinct framework and the strong inducing effect of the anionic group. Herein, a KVPO_(4)F/reduced graphene oxide(KVPF/r GO) hybrid was fabricated via a simple multi-step approach as the polyanionic cathode material for PIBs. Profiting from the small size of KVPF nanoparticles and their uniform distribution in the r GO framework, the assynthesized KVPF/r GO hybrid manifests a large discharge capacity of 103.2 mAh g^(-1) with an outstanding energy density of 436.5 Wh kg^(-1). Through r GO decoration, the hybrid also demonstrates remarkable rate and cycling properties. By employing ex-situ X-ray diffraction(XRD) and X-ray photoelectron spectroscopy(XPS) techniques, the potassium storage mechanism of KVPF was clearly revealed. The facile preparation procedure and superior properties endow it great application prospects in large-scale energy storage. | Jianzhi Xu Jiaying Liao Yifan Xu Jianbo Li Chuannan Zhu Jun Lin Xiaosi Zhou | 2022 | Journal of Energy Chemistry2022，31，5： | 1 |
| 10 | 肝脏移植术后糖尿病患者肠道微生物组的变化显示文摘Post-transplant diabetes mellitus(PTDM)increases the risk of graft failure and death in liver transplant(LT)recipients.Experimental studies have indicated that enteric dysbiosis mediated by immunosuppressive tacrolimus(TAC)could contribute to glucose disorders,but no data on human recipients with PTDM have been reported.Here,by combining high-throughput shotgun metagenomics sequencing and metabolomics profiling,we characterized the intestinal microbiome(IM)in LT recipient cohort with or without PTDM and deciphered the potential relationship among IM,TAC dosage,and diabetes.By comparing with both non-PTDM and classical type 2 diabetes mellitus(T2DM),we identified microbial signatures of PTDM,which was characterized by the enriched Proteobacteria and decreased Bacteroidetes.Additionally,the altered microbes,as well as the microbial metabolomics,correlated with the dosage of TAC.Specifically,the levels of beneficial microbes associated with PTDM were lowered in recipients with the high TAC trough concentrations(>5 ng·mL^(-1))than those with low ones(<5 ng·mL^(-1)),which was accompanied by reduced faecal metabolites involved in the biosynthesis of a-linolenic acid and arachidonic acid-lowering factors of developing T2DM.Moreover,these microbial signatures linked with the extent of glucose disorders in LT recipients.In summary,the faecal microbiome and metabolome differed between PTDM and non-PTDM patients,which were linked with TAC dosage.This study was the first to explore taxonomic alterations and bacterial gene functions to better understand the contribution of the IM to PTDM. | Qi Ling Yuqiu Han Yue Ma Xiaosen Wang Zheng Zhu Jingyu Wang Jiaying Cao Lin Xiaohan Jun Wang Baohong Wang | 2023 | Engineering2023，31，12： | 0 |
| 11 | Functions of Nitrogen,Phosphorus and Potassium in Energy Status and Their Influences on Rice Growth and Development显示文摘Nitrogen(N),phosphorus(P)and potassium(K)are important essential nutrients for plant growth and development,but their functions in energy status remains unclear.Here,we grew Nipponbare rice seedlings in a growth chamber for 20 d at 30℃/24℃day/night)under natural sunlight conditions with different nutrient regimes.The results showed that N had the strongest influence on the plant growth and development,followed by P and K.The highest nonstructural carbohydrate content,dry matter weight,net photosynthetic rate(Pn),ATP content,as well as NADH dehydrogenase,cytochrome oxidase and ATPase activities were found in the plants that received sufficient N,P and K.The lowest values of these parameters were detected in the N-deficient plants.Higher dry matter accumulation was observed in the K-deficient than in the P-deficient treatments,but there was no significant difference in the ratio of respiration rate to Pn between these two treatments,suggesting that differences in energy production efficiency may have accounted for this result.This hypothesis was confirmed by higher ATP contents and activities of NADH dehydrogenase,cytochrome oxidase and ATPase in the K-deficient plants than in the P-deficient plants.We therefore inferred different abilities in energy production efficiency among N,P and K in rice seedlings,which determined rice plant growth and development. | MA Jiaying CHEN Tingting LIN Jie FU Weimeng FENG Baohua LI Guangyan LI Hubo LI Juncai WU Zhihai TAO Longxing FU Guanfu | 2022 | Rice science2022，29，2： | 0 |
| 12 | Pharmacological effects of denervated muscle atrophy due to metabolic imbalance in different periods显示文摘Denervation-induced skeletal muscle atrophy can potentially cause the decline in the quality of life of patients and an increased risk of mortality.Complex pathophysiological mechanisms with dynamic alterations have been documented in skeletal muscle atrophy resulting from innervation loss.Hence,an in-depth comprehension of the key mechanisms and molecules governing skeletal muscle atrophy at varying stages,along with targeted treatment and protection,becomes essential for effective atrophy management.Our preliminary research categorizes the skeletal muscle atrophy process into four stages using microarray analysis.This review extensively discusses the pathways and molecules potentially implicated in regulating the four stages of denervation and muscle atrophy.Notably,drugs targeting the reactivare oxygen species stage and the inflammation stage assume critical roles.Timely intervention during the initial atrophy stages can expedite protection against skeletal muscle atrophy.Additionally,pharmaceutical intervention in the ubiquitin-proteasome pathway associated with atrophy and autophagy lysosomes can effectively slow down skeletal muscle atrophy.Key molecules within this stage encompass MuRF1,MAFbx,LC3II,p62/SQSTM1,etc.This review also compiles a profile of drugs with protective effects against skeletal muscle atrophy at distinct postdenervation stages,thereby augmenting the evidence base for denervation-induced skeletal muscle atrophy treatment. | JIAYING QIU YAN CHANG WENPENG LIANG MENGSI LIN HUI XU WANQING XU QINGWEN ZHU HAIBO ZHANG ZHENYU ZHANG | 2023 | BIOCELL2023，47，11： | 0 |
| 13 | Influencing factors of using behaviour for computational advertising under the theoretical model of UTAUT显示文摘Based on the UTAUT theoretical model, this paper discusses the applicability of the model incomputational advertising situations. Computational advertising relies on artificial intelligencetechnologies such as big data, cloud computing, new algorithms, and blockchain. Results showthat: performance expectation, effort expectation, and social impact have a positive influence onthe acceptance intention of computational advertising;stimulus has no significant influence onthe using behaviour of computational advertising;the acceptance intention of computationaladvertising has a positive influence on the using behaviour of computational advertising. Fourpoints should be paid attention to in the future computational advertising: paying attention tothe needs of users and realising accurate advertising;improving efforts and expectations andoptimising user experience;enhancing user interaction and user stickiness;protecting user privacyand improving user satisfaction. The core of computational advertising research in the fieldof humanities and social sciences is not dislocated from the traditional user-centred problemconsciousness. | Guiting Wang Jiaying Xu Shengliang Lin | 2023 | Journal of Control and Decision2023，10，1： | 0 |
| 14 | KVPO_(4)F/carbon nanocomposite with highly accessible active sites and robust chemical bonds for advanced potassium-ion batteries显示文摘KVPO_(4)F(KVPF)has been extensively investigated as the potential cathode material for potassium-ion batteries(PIBs)owing to its high theoretical capacity,superior operating voltage,and three-dimensional Kt conduction pathway.Nevertheless,the electrochemical behavior of KVPF is limited by the inherent poor electronic conductivity of the phosphate framework and unstable electrode/electrolyte interface.To address the above issues,this work proposes an infiltration-calcination method to confine the in-situ grown KVPF into the mesoporous carbon CMK-3(denoted KVPF@CMK-3).The assembled KVPF@CMK-3 nanocomposite features three-dimensional interconnected carbon channels,which not only offer abundant active sites and significantly accelerate K t/electron transport,but also prevent the growth of KVPF nanoparticle agglomerates,hence stabilizing the structure of the material.Additionally,V–F–C bonds are created at the interface of KVPF and CMK-3,which reduce the loss of F and stabilize the electrode interface.Thus,when tested as a cathode material for PIBs,the KVPF@CMK-3 nanocomposite delivers superior reversible capacitiy(103.2 mAh g^(-1) at 0.2 C),outstanding rate performance(90.1 mAh g^(-1) at 20 C),and steady cycling performance(92.2 mAh g^(-1) at 10 C and with the retention of 88.2%after 500 cycles).Moreover,its potassium storage mechanism is further examined by ex-situ XRD and ex-situ XPS techniques.The above synthetic strategy demonstrates the potential of KVPF@CMK-3 to be applied as the cathode for PIBs. | Jianzhi Xu Liping Duan Jiaying Liao Haowei Tang Jun Lin Xiaosi Zhou | 2023 | Green Energy & Environment2023，8，5： | 0 |
| 15 | 肺癌患者KDR基因酪氨酸激酶结构域的突变和多态性研究(英文)显示文摘Objective: Although the kinase insert domain-containing receptor (KDR) gene play an very important role in the metastasis of cancer and is also as one of the molecular targets used in cancer therapy, mutation in the tyrosine kinase (TK) domain of the KDR gene has not been reported. Here we detected the mutations and polymorphisms in the TK domain of KDR gene in human lung cancer patients and to give the basic evidence and clue for cancer prevention and target therapy. Methods: The entire sequence of exons 21, 22, 23 and 27 (which contain the coding sequence of tyrosine phosphorylation) in the TK domain of KDR gene in the patients with lung cancer and control healthy individuals were assayed by PCR and DNA sequencing. We also analyzed one non-coding single nucleotide polymorphisms (SNPs) in the KDR gene. Results: No mutations were found in exon 22, 23 and 27. One heterozygous mutation of c.+2837 in exon 21 was found at a frequency of 2.08% (2/96) in the patients with lung cancer and none were detected in the healthy control individuals. The mutation was from a G to a A resulting in substitution of arginine with histidine residue. Conclusion: Our data suggested that we should focus on the mutation or SNP in the other regions or the expression levels of KDR gene, and the function of c.+2837 mutation of KDR gene may be needed further study in the future. | Shejuan An Zhihong Chen Jian Su Jiaying Lin Ying Huang Hongyan Tang Yilong Wu | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，6： | 0 |
| 16 | Potential of Antibody-Dependent Cellular Cytotoxicity in Acute and Recovery Phases of SARS-CoV-2 Infection显示文摘Background:Severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)has caused a global pandemic that has resulted in millions of casualties.Although researchers have reported the existence of neutralizing antibodies and viral T cell immunity against SARS-CoV-2,little is known about the presence of antibody-dependent cellular cytotoxicity(ADCC)and its role in combating SARS-CoV-2 infection.Methods:Nineteen acute COVID-19 patients at the First Affiliated Hospital of Guangzhou Medical University from January to February,2020 and 55 recovery COVID-19 patients at the Second Peoples Hospital of Changde City from February,2020 to February,2021 were recruited in this study.Longitudinal plasma samples were collected.A virus-specific ADCC assay was performed to study the COVID-19 plasma samples.The correlations between ADCC and total IgG titer,including anti-RBD,anti-N,and neutralizing antibody titer were analyzed.Results:A high level of ADCC with 0.86%of IFN-g+CD107a+NK cells induced by anti RBD antibodies and with 0.54%of IFN-g+CD107a+NK cells induced by anti N antibodies was observed.This activity peaked at 3 weeks after disease onset with 1.16%and 0.63%of IFN-g+CD107a+NK cells induced by anti RBD and anti N antibodies respectively,declined to 0.32%and 0.32%of IFN-g+CD107a+NK cells respectively after more than 2 months,and persisted for 12 months after disease onset.The ADCC did not aggravate the severity of COVID-19 in terms of sequential organ failure assessment,although ADCC decreased with the age of COVID-19 patients.Interestingly,ADCC response is not correlated with neutralizing antibody titer or total IgG titers against S protein RBD and N protein in acute patients.ADCC in recovered patients showed a significant correlation with anti RBD IgG titer(R2=0.33,P<0.001).Conclusion:Antibodies from COVID-19 patients against the N protein and S protein RBD domains could stimulate high levels of ADCC response.Our results provide evidence that vaccination should not only focus on neutralizing antibodies but also binding antibodies that may facilitate the antiviral function of ADCC,especially in the elderly. | Tingting Cui Mingzhu Huang Xiaoling Su Zhengfang Lin Jiaying Zhong Xiaoyun Yang Zhongfang Wang | 2022 | Infectious Diseases & Immunity2022，2，2： | 0 |
| 17 | Scaffolds with anisotropic structure for neural tissue engineering显示文摘Nervous system injuries remain a great challenge due to limited natural tissue regeneration capabilities.Neural tissue engineering has been regarded as a promising approach for repairing nerve defects,which utilizes external biomaterial scaffolds to allow cells to migrate to the injury site and repair the tissue.Particularly,scaffolds with anisotropic structures biomimicking the native extracellular matrix(ECM)can effectively guide neural orientation and reconnection.Here,the advancements of scaffolds with anisotropic structures in the field of neural tissue engineering are presented.The fabrication strategies of scaffolds with anisotropic structures and their effects in vitro and in vivo are highlighted.We also discuss the challenges and provide a perspective of this field. | Yangnan Hu Hui Zhang Hao Wei Hong Cheng Jiaying Cai Xiaoyan Chen Lin Xia Huan Wang Renjie Chai | 2022 | Engineered Regeneration2022，3，2： | 0 |
| 18 | Shanghai Autism Early Development:An Integrative Chinese ASD Cohort显示文摘Why Was the Cohort Set Up?Autism spectrum disorder(ASD)is a child neurodevelopmental disorder,the onset of which is generally within 3 years of age,and often leads to lifelong impaired social and cognitive functions,which impose significant mental pressure and economic burdens on the family and society. | Yuan Dai Yuqi Liu Lingli Zhang Tai Ren Hui Wang Juehua Yu Xin Liu Zilin Chen Lin Deng Minyi Tao Hangyu Tan Chu‑Chung Huang Jiaying Zhang Qiang Luo Jianfeng Feng Miao Cao Fei Li | 2022 | Neuroscience Bulletin2022，38，12： | 0 |
| 19 | Reliable Scheduling Method for Sensitive Power Business Based on Deep Reinforcement Learning显示文摘The main function of the power communication business is to monitor,control and manage the power communication network to ensure normal and stable operation of the power communication network.Commu-nication services related to dispatching data networks and the transmission of fault information or feeder automation have high requirements for delay.If processing time is prolonged,a power business cascade reaction may be triggered.In order to solve the above problems,this paper establishes an edge object-linked agent business deployment model for power communication network to unify the management of data collection,resource allocation and task scheduling within the system,realizes the virtualization of object-linked agent computing resources through Docker container technology,designs the target model of network latency and energy consumption,and introduces A3C algorithm in deep reinforcement learning,improves it according to scene characteristics,and sets corresponding optimization strategies.Mini-mize network delay and energy consumption;At the same time,to ensure that sensitive power business is handled in time,this paper designs the business dispatch model and task migration model,and solves the problem of server failure.Finally,the corresponding simulation program is designed to verify the feasibility and validity of this method,and to compare it with other existing mechanisms. | Shen Guo Jiaying Lin Shuaitao Bai Jichuan Zhang Peng Wang | 2023 | Intelligent Automation & Soft Computing2023，，7： | 0 |
| 20 | Stimulating and harnessing circularly polarized luminescence of helically assembled carbonized polymer dots via interfacial dynamics显示文摘Stimulating and harnessing circularly polarized luminescence(CPL)is not only a sine qua non for fundamentally unveiling chirogenesis in physical chemistry,but also a pivotal prerequisite for implementation of such phenomenon in research fields including chiral optoelectronics and theranostics.Herein,red-emissive carbonized polymer dots(CPDs)-based helical structures were synthesized in this work via biomolecule-tailored organic–inorganic co-assembly strategy.The surface statesrelated chirality exhibits enhanced circular dichroism(CD)and CPL activities with anisotropic factors as high as gCD,max=5.4×10^(−3) and glum,max=1.5×10^(−2),respectively.The obtained CPL signals can be further manipulated in an excitationdependent manner,indicating that a synergistic-competition phenomenon exists between configurational chirality and intermolecular energy-transfer dynamics,which is further supported by simulations based on density function theory(DFT).Such tunable CPL behavior triggers revolutionary designs and applications of these chiral CPDs into the realm of chirality-related biological issues and next-generation chiral optoelectronics. | Jiaying Lin Rulin Liu Peixian Chen Yangfei Lv Junjie Hao Meijuan Chen Dongxiang Zhang Ruikun Pan Yiwen Li Xi Zhu Tingchao He Jiaji Cheng | 2023 | Aggregate2023，4，4： | 0 |
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