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| 1 | Clinical trial:Lactobacillus plantarum 299v(DSM 9843)improves symptoms of irritable bowel syndrome显示文摘AIM:To assess the symptomatic efficacy of Lactobacillus plantarum 299v(L.plantarum 299v)(DSM 9843) for the relief of abdominal symptoms in a large subset of irritable bowel syndrome(IBS) patients fulfilling the Rome Ⅲ criteria.METHODS:In this double blind,placebo-controlled,parallel-designed study,subjects were randomized to daily receive either one capsule of L.plantarum 299v(DSM 9843) or placebo for 4 wk.Frequency and intensity of abdominal pain,bloating and feeling of incomplete rectal emptying were assessed weekly on a visual analogue scale while stool frequency was calculated.RESULTS:Two hundred and fourteen IBS patients were recruited.After 4 wk,both pain severity(0.68 + 0.53 vs 0.92 + 0.57,P < 0.05) and daily frequency(1.01 + 0.77 vs 1.71 + 0.93,P < 0.05) were lower with L.plantarum 299v(DSM 9843) than with placebo.Similar results were obtained for bloating.At week 4,78.1 % of the patients scored the L.plantarum 299v(DSM 9843) symptomatic effect as excellent or good vs only 8.1 % for placebo(P < 0.01).CONCLUSION:A 4-wk treatment with L.plantarum 299v(DSM 9843) provided effective symptom relief,particularly of abdominal pain and bloating,in IBS patients fulfilling the Rome Ⅲ criteria. | Philippe Ducrotté Prabha Sawant Venkataraman Jayanthi | 2012 | World Journal of Gastroenterology2012，18，30： | 17 |
| 2 | Plant species with extremely small populations(PSESP) in China:A seed and spore biology perspective显示文摘Approximately one fifth of the world's plants are at risk of extinction.Of these,a significant number exist as populations of few individuals,with limited distribution ranges and under enormous pressure due to habitat destruction.In China,these most-at-risk species are described as 'plant species with extremely small populations'(PSESP).Implementing conservation action for such listed species is urgent.Storing seeds is one of the main means of ex situ conservation for flowering plants.Spore storage could provide a simple and economical method for fern ex situ conservation.Seed and spore germination in nature is a critical step in species regeneration and thus in situ conservation.But what is known about the seed and spore biology(storage and germination) of at-risk species? We have used China's PSESP(the first group listing) as a case study to understand the gaps in knowledge on propagule biology of threatened plant species.We found that whilst germination information is available for 28 species(23%of PSESP),storage characteristics are only known for 8%of PSESP(10 species).Moreover,we estimate that 60%of the listed species may require cryopreservation for long-term storage.We conclude that comparative biology studies are urgently needed on the world's most threatened taxa so that conservation action can progress beyond species listing. | Ellie Merrett Wade Jayanthi Nadarajan Xiangyun Yang Daniel Ballesteros Weibang Sun Hugh W.Pritchard | 2016 | Plant Diversity2016，38，5： | 6 |
| 3 | 炎症性肠病发病机制的新概念显示文摘溃疡性结肠炎(UC)和克隆病(CD)是全球性慢性疾病。在发病率以及其多种可能存在的致病因素的变化趋势使对其病因学产生许多新的理论和假说。流行病学调查已认识可能影响易感个体环境和遗传因素,已知微生物、消化道免疫系统缺陷和一些化学介质是影响起病的因素,但大多数研究仍处于实验阶段。 | Jayanthi V 钟良 | 1992 | 国外医学(消化系疾病分册)1992，12，3： | 5 |
| 4 | 印度南部2型糖尿病患者糖尿病视网膜病变相关危险因素的研究(英文)显示文摘目的:探究2型糖尿病患者糖尿病视网膜病变(DR)的严重度及受试者中糖尿病视网膜病变严重程度与其病程、糖化血红蛋白水平、高血压史、年龄和性别的相关性。方法:横断面研究。2012-05/06,采取简单随机抽样方法进行结构化问卷调查,收集100例年龄≥35岁糖尿病视网膜病变患者。进行描述性统计、单变量和多变量有序逻辑回归分析。用excel表进行数据录入,并用SPSS 21.0进行数据分析(P<0.05)。结果:100例患者,平均年龄53.16±10.81(35~78)岁。通过单因素分析发现,糖尿病视网膜病变严重度与年龄(P<0.01),糖尿病病程(P<0.001),糖化血红蛋白水平(P<0.001),糖尿病家族史(P<0.01),高血压病史(P<0.05),均呈正相关,高密度脂蛋白(HDL)及年龄与DR严重程度无相关性。除年龄因素外,上述所有因素均为影响糖尿病视网膜病变严重度的独立风险因素。结论:研究表明,糖尿病病程、糖化血红蛋白水平、糖尿病家族史、高血压病史以及性别与糖尿病视网膜病变严重程度密切相关。但多因素分析中,年龄、HDL因素与DR严重程度无关。因此,利用现有治疗手段的有效性和及时控制,可以预防和消除视力威胁性疾病,延缓DR的发生。 | Senthilvel Vasudevan Sumathi Senthilvel Jayanthi Sureshbabu | 2017 | 国际眼科杂志2017，17，9： | 4 |
| 5 | Genotype phenotype correlation in Wilson's disease within families-a report on four south Indian families显示文摘AIM: To study the genotype phenotype correlation in Wilson's disease (WD) patients within families. METHODS: We report four unrelated families from South India with nine members affected with WD. Phenotype was classified as per international consensus phenotypic classifi cation of WD. DNA was extracted from peripheral blood and 21 exons of ATP7B gene and flanking introns were amplified by polymerase chain reaction (PCR). The PCR products were screened for mutations and the aberrant products noted on screening were sequenced. RESULTS: Four separate ATP7B mutations were found in the four families. ATP7B mutations were identical amongst affected members within each family. Three families had homozygous mutations of ATP7B gene while one family had compound heterozygous mutation, of which only one mutation was identifi ed. We noted concordance between ATP7B gene mutation and Wilson's disease phenotype amongst members within each family. The age of onset of symptoms or of detection of asymptomatic disease, baseline serum ceruloplasmin and baseline urinary copper levels were also similar in affected members of each family. Minor differences in phenotype and baseline serum ceruloplasmin level were noted in one family.CONCLUSION: We report concordance between ATP7B mutation and WD phenotype within each family with > 1 member affected with WD. Homozygous ATP7B mutation was present in 3 of the 4 families studied. Our report supports allelic dominance as a determinant of WD phenotype. However, in one family with compound heterozygous mutation, there was a similar WD phenotype which suggests that there may be other factors determining the phenotype. | S Santhosh RV Shaji CE Eapen V Jayanthi S Malathi P Finny N Thomas M Chandy G Kurian GM Chandy | 2008 | World Journal of Gastroenterology2008，14，29： | 3 |
| 6 | Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats显示文摘 | Ali Keshavarzian Ashkan Farhadi Christopher B. Forsyth Jayanthi Rangan Shriram Jakate Maliha Shaikh Ali Banan Jeremy Z. Fields | 2009 | Journal of Hepatology2009，，3： | 3 |
| 7 | Antibacterial forsterite (Mg_(2)SiO_(4)) scaffold: A promising bioceramic for load bearing applications显示文摘In the current work,forsterite samples with different surface area were investigated for its antibacterial activity.Dissolution studies show that the lower degradation of forsterite compared to other silicate bioceramics,which is a desirable property for repairing bone defects.Forsterite scaffold shows superior compressive strength than the cortical bone after immersion in simulated body fluid.Bactericidal tests indicate that the forsterite had inhibition effect on the growth of clinical bacterial isolates.Forsterite may be a suitable candidate material for load bearing applications with enhanced mechanical properties and lower degradation rate. | Rajan Choudhary Ankita Chatterjee Senthil Kumar Venkatraman Sivasankar Koppala Jayanthi Abraham Sasikumar Swamiappan | 2018 | Bioactive Materials2018，3，3： | 3 |
| 8 | An overview of pyrethroid insecticides显示文摘 | Anudurga Gajendiran Jayanthi Abraham | 2018 | Frontiers in Biology2018，13，2： | 2 |
| 9 | Pathogenesis of cholangitis in obstructive jaundice-revisited显示文摘 | Navaneethan U Jayanthi V Mohan P | 2011 | Minerva Gastroenterol Dietol2011，57，1： | 1 |
| 10 | Verrucous hemangioma of the glans penis显示文摘 | Akyol L Jayanthi VR Luquette MH | | 0，，01： | 1 |
| 11 | Modification of the Koyanagi technique for the single stage repair of proximal hypospadias 显示文摘 | Emir H Jayanthi VR Nitahara K | 2000 | J Urol2000，164，3： | 1 |
| 12 | Effect of variable viscosity on non-Darcy free or mixed convection flow on a vertical surface in a fluid saturated porous medium 显示文摘 | Jayanthi S Kumari M | 2006 | Mechanics Research Communication2006，33，2： | 1 |
| 13 | How to calculate the significant caries index显示文摘 | Makiko Nishi Douglas Bratthall Jayanthi Stjemsward | | WHO Collaborating Centre Faculty of Odontology University of Malmo0，，： | 1 |
| 14 | Differential regulation of mammlian brain - specific proline transporter by calcium and calcium -dependent protein kinases显示文摘 | Jayanthi LD Wilson J J Montalvo J | 2000 | Br J Pharmacol2000，129，3： | 1 |
| 15 | An eeo friendly and solvent free method for the synthesis of Zinc oxide nano particles using glycerol as organic dispersant 显示文摘 | SARAVANAN M DHIVAKAR S JAYANTHI S S | 2012 | Materials Letters2012，67，1： | 1 |
| 16 | Secreted protein acidic and rich in cysteine as a regulator of murine ovarian cancer growth and chemosensitivity显示文摘 | Shawna L. Bull Phelps Juliet Carbon Andrew Miller Emely Castro-Rivera Shanna Arnold Rolf A. Brekken Jayanthi S. Lea | 2009 | American Journal of Obstetrics and Gynecology2009，，2： | 1 |
| 17 | Methamphetamine induces neuronal apoptosis via cross - talks between endoplasmic reticulum and mitochondria- dependent death cascades显示文摘 | Jayanthi S Deng X Noailles PA | 2004 | Faseb J2004，18，2： | 1 |
| 18 | Effect of hypos- padias on sexual function and reproduction 显示文摘 | Singh JC Jayanthi VR Gopalakrishnan G | 2008 | Indian J Urol2008，24，2： | 1 |
| 19 | Ceramic powder synthesis by spray pyralsis显示文摘 | Messing G L Zhang Shi-Chang Jayanthi G V | 1993 | Journal of American Ceramics Society1993，76，11： | 1 |
| 20 | Modification of the Koyanagi technique for the single stage repair of proximal hy-pospadias显示文摘 | Emir H Jayanthi VR Nitahara K | | 0，，： | 1 |
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