|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 普瑞巴林治疗糖尿病周围神经痛的疗效、安全性和耐受性显示文摘目的:通过分析7项普瑞巴林治疗糖尿病周围神经病(DPN)的临床研究,评估普瑞巴林在其有效剂量范围内的疗效、安全性和耐受性;评估每日两次给药(BID)和每日三次给药(TID)的疗效差异; | Roy Freeman Edith Durso-Decruz Birol Emir | 2011 | 中国新药杂志2011，20，6： | 10 |
| 2 | Novel role for gabapentin in neuroprotection of central nervous system in streptozotocine-induced diabetic rats显示文摘Aim: To investigate the effect of gabapentin on neural [neuron-specific enolase (NSE)] and glial markers [glial fibrillary acidic protein (GFAP) and S 100B] in different brain regions of diabetic rats. Methods: Diabetes was induced by a single intraperitoneal injection of streptozotocine (50mg/kg body weight). Rats in one diabetic group received gabapentin (50mg·kg^-1·d^-1) and rats in the other diabetic group received vehicle only for 6 weeks. The levels of GFAP, S100B, and NSE were determined by immunoblotting in the hippocampus, cortex, and cerebellum. Lipid peroxidation (LPO as malondialdehyde+4-hydroxyalkenals) and glutathione (GSH) levels were also determined in the same brain parts. Results: Total and degraded GFAP content and S100B protein expression in different areas of brain tissues significantly increased in diabetic rats compared to control rats. Similarly, NSE levels were also significantly elevated in hyperglycemic rats. In addition, there was a significant increase in LPO levels in the diabetic rat brain compared to control rat brains. Pretreatment with gabapentin prevented the upregulation of GFAP, S 100B, and NSE in all brain regions of diabetic rats. The level of LPO was reduced, but not completely halted, by treatment with gabapentin. Conclusion:These results suggest that diabetes causes glial and neuronal injury, possibly as a result of elevated oxidative stress, and that gabapentin protects neurons and glial cells. Thus, we predict that gabapentin treatment will attenuate the hippocampal and cortical neurodegeneration observed during diabetes mellitus in rats. | Giyasettin BAYDAS Ertugrul SONKAYA Mehmet TUZCU Abdullah YASAR Emir DONDER | 2005 | Acta Pharmacologica Sinica2005，26，4： | 5 |
| 3 | Total hepatectomy and liver transplantation as a two-stage procedure for fulminant hepatic failure: A safe procedure in exceptional circumstances显示文摘AIM: To evaluate the outcomes of two-stage liver transplant at a single institution, between 1993 and March 2015.METHODS: We reviewed our institutional experience with emergency hepatectomy followed by transplantation for fulminant liver failure over a twenty-year period. A retrospective review of a prospectively maintained liver transplant database was undertaken at a national liver transplant centre. Demographic data, clinical presentation, preoperative investigations, cardiocirculatory parameters, operative and postoperative data were recorded.RESULTS: In the study period, six two-stage liver transplants were undertaken. Indications for transplantation included acute paracetamol poisoning(n = 3), fulminant hepatitis A(n = 1), trauma(n = 1) and exertional heat stroke(n = 1). Anhepatic time ranged from 330 to 2640 min. All patients demonstrated systemic inflammatory response syndrome in the first post-operative week and the incidence of sepsis was high at 50%. There was one mortality, secondary to cardiac arrest 12 h following re-perfusion. Two patients required re-transplantation secondary to arterial thrombosis. At a median follow-up of 112 mo, 5 of 6 patients are alive and without evidence of graft dysfunciton.CONCLUSION: Two-stage liver transplantation represents a safe and potentially life-saving treatment for carefully selected exceptional cases of fulminant hepatic failure. | Rebeca Sanabria Mateos Niamh M Hogan Dimitri Dorcaratto Helen Heneghan Venkatesh Udupa Donal Maguire Justin Geoghegan Emir Hoti | 2016 | World Journal of Hepatology2016，8，4： | 3 |
| 4 | Optical frequency synthesizer with an integrated erbium tunable laser显示文摘Optical frequency synthesizers have widespread applications in optical spectroscopy,frequency metrology,and many other fields.However,their applicability is currently limited by size,cost,and power consumption.Silicon photonics technology,which is compatible with complementary-metal-oxide-semiconductor fabrication processes,provides a low-cost,compact size,lightweight,and low-power-consumption solution.In this work,we demonstrate an optical frequency synthesizer using a fully integrated silicon-based tunable laser.The synthesizer can be self-calibrated by tuning the repetition rate of the internal mode-locked laser.A 20 nm tuning range from 1544 to 1564 nm is achieved with~10−13 frequency instability at 10 s averaging time.Its flexibility and fast reconfigurability are also demonstrated by fine tuning the synthesizer and generating arbitrary specified patterns over time-frequency coordinates.This work promotes the frequency stability of silicon-based integrated tunable lasers and paves the way toward chip-scale lowcost optical frequency synthesizers. | Ming Xin Nanxi Li Neetesh Singh Alfonso Ruocco Zhan Su Emir Salih Magden Jelena Notaros Diedrik Vermeulen Erich P.Ippen Michael R.Watts Franz X.Kartner | 2019 | Light(Science & Applications)2019，8，1： | 2 |
| 5 | 阿里敲响亚洲证交所的警钟显示文摘阿里巴巴做出在美国上市的决定也向亚洲的证交所敲响了警钟。有些公司希望采用的治理结构不再是标准的一股一票模式的单层股权结构。除非他们表明能够满足这些公司的要求,否则这些证交所会错失高价值公司上市带来的良机。 | Emir Hrnjic | 2014 | 首席财务官2014，0，9X： | 2 |
| 6 | Amperometric sensor for L-ascorbic acid determination base on MnO2bulk modified screen printed electrode显示文摘 | Emir Turkusic Vladimir Milicevic Hamid Tahmiscija | 2000 | Fresenius J Anal Chem2000，368，： | 2 |
| 7 | Do FDI patterns differ between manufacturing and service sector in CEE countries显示文摘 | Vesna Babic-Hodovic Eldin Mehic Emir Agic | 2010 | Journal of US-China Public Administration2010，7，3： | 2 |
| 8 | Time to onset of neuropathic pain reduetion:a retrospective analysis of da- ta from nine controlled trials o{ pregabalin for painful dia- betic peripheral neuropathy and postherpetic neuralgia 显示文摘 | Sharma U Griesing T Emir B | 2010 | Am J Ther2010，17，6： | 1 |
| 9 | Modification of the Koyanagi technique for the single stage repair of proximal hypospadias 显示文摘 | Emir H Jayanthi VR Nitahara K | 2000 | J Urol2000，164，3： | 1 |
| 10 | Paperless, Optimized and Intelligent Business by Using Successful Business Process Management Concepts显示文摘 | Emir Zunic Almir Djedovic Bahira Zunic | 2016 | 通讯和计算机(中英文版)2016，13，5： | 1 |
| 11 | Comparison of radiofrequency tissue volume reduction and submucosal resection with microdebrider in inferior turbinate hypertrophy显示文摘 | Kizilkaya Z Ceylan K Emir H | 2008 | Otolaryngol Head Neck Surg2008，138，2： | 1 |
| 12 | Successful treatment with interferon alfa in infiltrating angiolipoma:a case presenting with KasabachMerritt syndrome显示文摘 | Akyuz C Emir S Buyukpamukcu M | 2003 | Arch Dis Child2003，88，1： | 1 |
| 13 | Diagnostic Laparoscopy in Prolonged Jaundice 显示文摘 | Senyuz O F Yesilda q E Emir H | 2001 | J Pediatr Surg2001，36，3： | 1 |
| 14 | Modification of the Koyanagi technique for the single stage repair of proximal hy-pospadias显示文摘 | Emir H Jayanthi VR Nitahara K | | 0，，： | 1 |
| 15 | Blood pressure is associated with the presence and severity of nonalcoholic fatty liver disease across the spectrum of cardiometabolic risk显示文摘 | Ehimen C. Aneni Ebenezer T. Oni Seth S. Martin Michael J. Blaha Arthur S. Agatston Theodore Feldman Emir Veledar Raquel D. Con?eicao Jose A.M. Carvalho Raul D. Santos Khurram Nasir | 2015 | Journal of Hypertension2015，，6： | 1 |
| 16 | The morphology of thefemur in development dysplasia of the hip显示文摘 | Philip C Noble NS Emir Kamaric | 1998 | Journal of Bone and Joint Surgery1998，80，： | 1 |
| 17 | Pulmonary Complications After Elective Liver Transplantation—Incidence, Risk Factors, and Outcome显示文摘 | Eric Levesque Emir Hoti Daniel Azoulay Isabelle Honore Bruno Guignard Eric Vibert Philippe Ichai Fadi Antoun Faouzi Saliba Didier Samuel | 2012 | Transplantation Journal2012，，5： | 1 |
| 18 | Effect of environmental factors on species diversity of the Yenice Hot Spot Forests in Turkey显示文摘We quantified the diversity of vascular plant species and described soil properties and topographical and climatic conditions of the Citdere and Kavakli Nature Reserves in the Yenice Forest of Turkey. We used the Shannon-Weiner and Simpson's indices of diversity,Margalef's index of species richness and Pielou's evenness index to quantify the structure of vascular plant assemblages. We measured soil parameters(NO_3^-, NH_4^+,available P, Mg^(++), K^+, Na^+, Ca^(++), organic matter, pH,soil moisture), elevation, slope gradient and aspect and their correlations with plant community parameters. In total, we recorded and identified 207 species and subspecies in the study area. Species cover, richness and diversity indices varied significantly by vegetation type(P < 0.01). Available NO_3^- and Ca++ in the soil were important factors for the area and species representation in the species-environment correlations estimated for the Kavakli area. Available NO_3^-,pH, organic matter, Ca^(++) and K^+ in the soil were important factors for the area and species representation in the species-environment correlations analysed for the Citdere area. | Sevda Turkis Emire Elmas | 2018 | Journal of Forestry Research2018，29，6： | 1 |
| 19 | Relationship between pain relief and improvements in patient function/quality of life in patients with painful diabetic peripheral neuropathy or postherpetic neuralgia treated with pregabalin显示文摘 | Vinik A Emir B Cheung R | 2013 | Clinical Therapeutics2013，35，5： | 1 |
| 20 | A rare case of asymptomatic bilateral submandibular gland sialolithiasis:a giant, fistulized calculus on the right and multiple calculi on the left 显示文摘 | Emir H Kaptan ZK Uzunkulaoglu H | 2010 | Ear Nose Throat J2010，89，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员