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| 1 | Management of necrotizing pancreatitis显示文摘Infection complicating pancreatic necrosis leads to persisting sepsis, multiple organ dysfunction syndrome and accounts for about half the deaths that occur following acute pancreatitis. Severe cases due to gallstones require urgent endoscopic sphincterotomy. Patients with pancreatic necrosis should be followed with serial contrast enhanced computed tomography (CE-CT) and if infection is suspected fine needle aspiration of the necrotic area for bacteriology (FNAB) should be undertaken. Treatment of sterile necrosis should initially be non-operative. In the presence of infection necrosectomy is indicated. Although traditionally this has been by open surgery, minimally invasive procedures are a promising new alternative. There are many unresolved issues in the management of pancreatic necrosis. These include, the use of antibiotic prophylaxis, the precise indications for and frequency of repeat CE-CT and FNAB,and the role of enteral feeding. | John Slavin Paula Ghaneh Robert Sutton Mark Hartley Peter Rowlands Conall Garvey Mark Hughes John Neoptolemos | 2001 | World Journal of Gastroenterology2001，7，4： | 21 |
| 2 | Adjuvant therapy in pancreatic cancer显示文摘The outlook for patients with pancreatic cancer has been grim. There have been major advances in the surgical treatment of pancreatic csncer, leading to a drsmatic reduction in post-operative mortality from the development of high volume specialized centres. This stimulated the study of adjuvant and neoadjuvant treatments in pancreatic cancer including chemoradiotherapy and chemotherapy. Initial protocols have been based on the original but rather small GITSG study first reported in 1985. There have been two large European trials totalling over 600 patients (EORTC and ESPAC-1) that do not support the use of chemoradiation as adjuvant therapy. A second major finding from the ESPAC-1 trial (541 patients randomized) was some but not conclusive evidence for a survival benefit associated with chemotherapy. A third major finding from the ESPAC-1 trial was that the quality of life was not affected by the use of adjuvant treatments compared to surgery alone.The ESPAC-3 trial aims to assess the definitive use of adjuvant chemotherapy in a randomized controlled trial of 990 patients. | Paula Ghaneh John Slavin Robert Sutton Mark Hartley John P Neoptolemos | 2001 | World Journal of Gastroenterology2001，7，4： | 3 |
| 3 | Ecosystem service delivery in Karst landscapes: anthropogenic perturbation and recovery显示文摘Covering extensive parts of China, Karst landscapes are exceptional because rapid and intensive land use change has caused severe ecosystem degradation within only the last 50 years. The twentieth century intensification in food production through agriculture has led to a rapid deterioration of soil quality, evidenced in reduced crop production and rapid loss of soil. In many areas, a tipping point appears to have been passed as basement rock is exposed and 'rocky desertification' dominates. Through the establishment of the 'Soil processes and ecological services in the karst critical zone of SW China'(SPECTRA)Critical Zone Observatory(CZO) we will endevaour to understand the fundmental processes involved in soil production and erosion, and investigate the integrated geophysical-geochemical-ecological responses of the CZ to perturbations. The CZ spans a gradient from undisturbed natural vegetation through human perturbed landscapes.We seek to understand the importance of heterogeneity insurface and below-ground morphology and flow pathways in determining the spatial distribution of key stocks(soil,C, vegetation, etc.) and their control on ecosystem service delivery. We will assess the extent to which the highly heterogeneous critical zone resources can be restored to enable sustainable delivery of ecosystem services. This paper presents the CZO design and initial assessment of soil and soil organic carbon stocks and evidence for their stability based on caesium-137(^(137) Cs) data. | Timothy Quine Dali Guo Sophie M.Green Chenglong Tu Iain Hartley Xinyu Zhang Jennifer Dungait Xuefa Wen Zhaoliang Song Hongyan Liu Heather Buss Timothy Barrows Richard Evershed Penny Johnes Jeroen Meersmans | 2017 | Acta Geochimica2017，36，3： | 3 |
| 4 | Social network markets: a new definition of the creative industries显示文摘 | Jason Potts Stuart Cunningham John Hartley Paul Ormerod | 2008 | Journal of Cultural Economics2008，，3： | 3 |
| 5 | Total mesorectal excision: Assessment of the laparoscopic approach显示文摘 | John E. Hartley Brian J. Mehigan Akhtar E. Qureshi Graham S. Duthie Peter W. R. Lee Dr. John R. T. Monson | 2001 | Diseases of the Colon & Rectum2001，，3： | 2 |
| 6 | Social network markets: a new definition of the creative industries显示文摘 | JASON POTTS JOHN HARTLEY STUART CUNNIN- GHAM and PAUL OMEROD | 2008 | Journal of Cul- tural Economics2008，，6： | 1 |
| 7 | Social network markets:a new definition of thecreative industries 显示文摘 | Jason Potts Stuart Cunningham John Hartley and Paul Ormerod | 2008 | Journal of Cuhural Economics2008，3，2008： | 1 |
| 8 | Characteristies of the interaction of anthrapyrazole anticancer agents with Deoxyribonucleic acid: Structural requirements for DNA binding,Intercalation,and photosensitization显示文摘 | Hartley K R Zuo E T | 1988 | Mol Pharmaco1988，33，： | 1 |
| 9 | Total mesorectal excision: Assessment of the laparoscopic approach显示文摘 | John E. Hartley Brian J. Mehigan Akhtar E. Qureshi Graham S. Duthie Peter W. R. Lee Dr. John R. T. Monson | 2001 | Diseases of the Colon & Rectum2001，，3： | 1 |
| 10 | Social network markets: a new definition of the creative industries显示文摘 | Jason Potts Stuart Cunningham John Hartley Paul Ormerod | 2008 | Journal of Cultural Economics2008，，3： | 1 |
| 11 | Social network markets:a new definition of the creative industries显示文摘 | Jason Potts Stuart Cunning ham John Hartley E Paul Ormerod | 2008 | JCult2008，，2008： | 1 |
| 12 | Creative Industries Come to China(MATE)显示文摘 | John Hartley Lucy Montgomery | 2009 | Chinese Journal of Communication2009，2，1： | 1 |
| 13 | A comparison of mesalamine suspention enema and oral sulfasalazine for treatment of active distal ulcerative colitis in adults显示文摘 | Lori K Hartley C Cornelius D Peter R John Orchard | 1995 | The American Journal of Gastroenterology1995，90，5： | 1 |
| 14 | Rectus Flap Reconstruction Decreases Perineal Wound Complications After Pelvic Chemoradiation and Surgery: A Cohort Study显示文摘 | David B. Chessin MD John Hartley MD Alfred M. Cohen MD Madhu Mazumdar PhD Peter Cordeiro MD Joseph Disa MD Babek Mehrara MD Bruce D. Minsky MD Philip Paty MD Martin Weiser MD W. Douglas Wong MD Jose G. Guillem MD MPH | 2005 | Annals of Surgical Oncology2005，，2： | 1 |
| 15 | A Case-Control Study of Laparoscopic Right Hemicolectomy vs. Open Right Hemicolectomy显示文摘 | Richard P. Baker M.R.C.S. Liviu V. Titu F.R.C.S. John E. Hartley M.D. Peter W. R. Lee M.D. John R. T. Monson M.D | 2004 | Diseases of the Colon & Rectum2004，，10： | 1 |
| 16 | Food-entrained rhyth- mic expression of PER2 and BMAL1 in murine megakaryocytes does not correlate with circadian rhythms in megakaryopoiesis 显示文摘 | Hartley PS John Sheward W French K | 2008 | J Thromb Haomost2008，6，7： | 1 |
| 17 | Creative Industries 显示文摘 | John Hartley | 2005 | London : Blackwell Publishing2005，，： | 1 |
| 18 | The impact of CO2 emissions trading on firm profits and market prices显示文摘 | Robin Smalel Murray Hartley Cameron Hepburn John Ward Michael Grubb | 2006 | Climate Policy2006，，6： | 1 |
| 19 | Social network markets: a new definition of the creative industries显示文摘 | Jason Potts Stuart Cunningham John Hartley Paul Ormerod | 2008 | Journal of Cultural Economics2008，，3： | 1 |
| 20 | Stapling procedure for haemorrhoids versus Milligan-Morgan haemorrhoidectomy: randomised controlled trial显示文摘 | Brian J Mehigan John RT Monson John E Hartley | 2000 | The Lancet . 2000 (9206)2000，，9206： | 1 |
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