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| 1 | Lipopolysaccharide Enhances the Production of Nicotine-Induced Prostaglandin E2 by an Increase in Cyclooxygenase-2 Expression in Osteoblasts显示文摘以前的研究显示了那脂肪的多糖(LPS ) 在匾的 fromGram 否定的细菌导致前列腺素 E_2 (PGE_2 ) 的版本,它在吸烟的 periodontitis,和那棵烟草支持牙槽的骨头再吞可能是为 periodontitis 的发展和严厉的一个重要风险因素。我们在碱性磷酸酶(ALPase ) 上决定了烟碱 andLPS 的效果活动, PGE_2 生产,和表示 ofcyclooxygenase (COX-1, COX-2 ) , PGE_2 受体 Ep1-4,和在人的 osteoblastic Saos-2 房间的巨噬细胞殖民地刺激因素(M-CSF ) 。房间与 10 ~ 是有教养的(-3) M 烟碱面对 0, 1,或 10 μ g /ml LPS,或与 LPS 独自一个。ALPase 活动独自在与烟碱或 LPS 有教养的房间减少了,并且在与烟碱和 LPS 有教养的那些进一步减少了,而 PGE_2 生产显著地在前者增加了并且在后者进一步增加了。由自己,烟碱没影响 COX-1, COX-2,任何 PGE_2 受体,或 M-CSF 的表示,但是烟碱和 LPS 什么时候是现在, COX-2 的表示, Ep3, Ep4,和 M-CSF,显著地增加。10 ~ 的同时的增加(-4) M 消炎痛在 ALPase 活动, PGE_2 生产,和 M-CSF 表示消除了烟碱和 LPS 的效果。proteinkinase A 的 Phosphorylation 在与烟碱和 LPS 有教养的房间高。这些结果建议 LPS 由造骨细胞的 COX-2 表示的增加提高导致烟碱的 PGE_2 的生产, thatnicotine-LPS-induced PGE_2 首先在 autocrine orparacnne 模式与造骨细胞 Ep4 受体交往,并且 nicotine-LPS-induced PGE_2 然后减少 ALPase 活动和 increasesM-CSF 表示。 | Maiko SHOJI Natsuko TANABE Narihiro MITSUI Naoto SUZUKI Osamu TAKEICHI Tomoko KATONO Akira MOROZUMI Masao MAENO | 2007 | Acta Biochimica et Biophysica Sinica2007，39，3： | 9 |
| 2 | Feasibility of initial endoscopic common bile duct stone removal in patients with acute cholangitis显示文摘AIM To investigate the feasibility of initial endoscopic common bile duct(CBD) stone removal in patients with acute cholangitis(AC).METHODS A single-center,retrospective study was conducted between April 2013 and December 2014 and was approved by the Medical Ethics Committee at our institution.Written informed consent was obtained from each patient prior to the procedure.The cohort comprised 31 AC patients with CBD stones who underwent endoscopic biliary drainage(EBD) for na?ve papilla within 48 h after AC onset.We retrospectively divided the participants into two groups: 19 patients with initial endoscopic CBD stone removal(initial group) and 12 patients with delayed endoscopic CBD stone removal(delayed group).We evaluated the feasibility of initial endoscopic CBD stone removal in patients with AC.RESULTS We observed no significant differences between the groups regarding patient characteristics.According to the assessments based on the Tokyo Guidelines,the AC severity of patients with initial endoscopic CBD stone removal was mild to moderate.The use of antithrombotic agents before EBD was less frequent in the initial group than in the delayed group(11% vs 58%,respectively; P = 0.004).All the patients underwent successful endoscopic CBD stone removaland adverse events did not differ significantly between the groups.The number of endoscopic retrograde cholangiopancreatography procedures was significantly lower in the initial group than in the delayed group [median(interquartile range) 1(1-1) vs 2(2-2),respectively; P < 0.001].The length of hospital stay was significantly shorter for the initial group than for the delayed group [10(9-15) vs 17(14-20),respectively; P = 0.010].CONCLUSION Initial endoscopic CBD stone removal in patients with AC may be feasible when AC severity and the use of antithrombotic agents are carefully considered. | Akira Yamamiya Katsuya Kitamura Yu Ishii Yuta Mitsui Tomohiro Nomoto Hitoshi Yoshida | 2017 | World Journal of Clinical Cases2017，5，7： | 5 |
| 3 | Non-exposed endoscopic wall-inversion surgery as a novel partial gastrectomy technique显示文摘 | Takashi Mitsui Keiko Niimi Hiroharu Yamashita Osamu Goto Susumu Aikou Fumihiko Hatao Ikuo Wada Nobuyuki Shimizu Mitsuhiro Fujishiro Kazuhiko Koike Yasuyuki Seto | 2014 | Gastric Cancer2014，，3： | 5 |
| 4 | The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells显示文摘 | Kaoru Mitsui Yoshimi Tokuzawa Hiroaki Itoh Kohichi Segawa Mirei Murakami Kazutoshi Takahashi Masayoshi Maruyama Mitsuyo Maeda Shinya Yamanaka | 2003 | Cell2003，，5： | 3 |
| 5 | The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells显示文摘 | Kaoru Mitsui Yoshimi Tokuzawa Hiroaki Itoh Kohichi Segawa Mirei Murakami Kazutoshi Takahashi Masayoshi Maruyama Mitsuyo Maeda Shinya Yamanaka | 2003 | Cell2003，，5： | 2 |
| 6 | THE NUMERICAL STABILITY OF THE θ-METHOD FOR DELAYDIFFERENTIAL EQUATIONS WITH MANY VARIABLEDELAYS显示文摘1.IntroductionInthispaper,wewillinvestigatethenumericalsolutionsofthefollowinginitialvalueproblemsforDDEswithmanyvariabledelayswherea,bl,b2,...,bmandcoEC,0 | Lin Qiu Taketomo Mitsui(Graduate School of Human Informatics, Nagoya University, Face-Cho, Chikusa-km, Nagoya,464-8601, Japan)Jiao-xun Kuang(Department of Mathematics, Shanghai Normal University, 100 Guilin Road, Shanghai200234, China) | 1999 | Journal of Computational Mathematics1999，17，5： | 2 |
| 7 | Ion chromatography for determination of nitrite and nitrate in seawater using monolithic ODS columns显示文摘 | Kazuaki Ito Yohichi Takayama Nobuyuki Makabe Ryo Mitsui Takeshi Hirokawa | 2005 | Journal of Chromatography A2005，，1： | 2 |
| 8 | Clinical outcomes of endoscopic ultrasonography-guided transmural drainage using plastic stent and nasocystic drain for pancreatic and peripancreatic collections显示文摘To the Editor:Pancreatic and peripancreatic collections(PCs)develop from acute pancreatitis(AP),chronic pancreatitis,surgery,or trauma.The 2012 revised Atlanta classification[1]of AP classified local complications into the following 4 PC types:acute peripancreatic fluid collection(<4 weeks after the onset of acute interstitial edematous pancreatitis),acute necrotic collection(<4 weeks after the onset of acute necrotizing pancreatitis),pancreatic pseudocyst(PPC;≥4 weeks after the onset of acute interstitial edematous pancreatitis),and walled-off necrosis(WON;≥4 weeks after the onset of acute necrotizing pancreatitis).Endoscopic ultrasonographyguided transmural drainage(EUS-TD)has been reported to be a minimally invasive procedure for patients with PCs[2–4].This study aimed to investigate the clinical outcomes of EUS-TD for PCs. | Katsuya Kitamura Akira Yamamiya Yu Ishii Yuta Mitsui Hitoshi Yoshida | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 2 |
| 9 | Water mist formation in vapor-mist dielectrics and its effect显示文摘 | Nagaki Y Itabashi S Mitsui H | 1994 | Electrical Engineering in Japan1994，114，3： | 1 |
| 10 | The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells显示文摘 | Mitsui K Tokuzawa Y Itoh H | 2003 | Cell2003，113，5： | 1 |
| 11 | Relations Between Surface Roughness Indexes and Bond Strength Between CFRP Sheets and Concrete显示文摘 | MITSUI M FUKUZAWA K NUMAO T | 2000 | Journal of the Society of Material Science2000，49，6： | 1 |
| 12 | Ion chromatography for determination of nitrite and nitrate in seawater using monolithic ODS columns 显示文摘 | Kazuaki It o Yohichi Takayama Nobuyuki Makabe Ryo Mitsui Takeshi Hirokawa | 2005 | Journal of Chromatography A2005，，1083： | 1 |
| 13 | Advances in soil microbial ecology and the biodiversity显示文摘 | Hattori T Mitsui H Haga H 1997 | 1997 | Antonie Van Leeuwenhoek1997，72，： | 1 |
| 14 | Endothelin-1 is produced and secreted by neonatal rat cardiac myocytes in vitro 显示文摘 | Suzuki J Kumazaki T Mitsui Y | 1993 | Biochem Biophys Res Commnu1993，191，3： | 1 |
| 15 | Beneficial effect of tacrolimus on myasthenia gravis with thymoma 显示文摘 | Mitsui T Kunishige M Ichimiya M | 2007 | Neurologist2007，13，2： | 1 |
| 16 | Control mechanism of the circadian clock for timing of cell division in vivo显示文摘 | Matsuo T Yamaguchi S Mitsui S | 2003 | Science2003，302，5643： | 1 |
| 17 | Total hip arthroplasty using a cylindrical cementless stem in patients with a small physique显示文摘 | Nakamura Y Mitsui H Kikuchi A | 2011 | J Arthroplasty2011，26，： | 1 |
| 18 | The homeoprotein nanog is required for maintenance of pluripotency in mouse epiblast and es cells显示文摘 | Mitsui K Tokuzawa Y Itoh H | 2003 | Cell2003，113，5： | 1 |
| 19 | Phase equilibria in the Ti–Al binary system显示文摘 | I Ohnuma Y Fujita H Mitsui K Ishikawa R Kainuma K Ishida | 2000 | Acta Materialia2000，，12： | 1 |
| 20 | Expression of ECRG4 is an independent prognostic factor for poor survivalin patients with esophageal squamous cell carcinoma显示文摘 | Yoichiro Mori Hideyuki Ishiguro Yoshiyuki Kuwabara Masahiro Kimura Akira Mitsui Horoki Kurehara Ryota Mori Keisuke Tomoda Ryo Ogawa Takeyasu Katada Koshiro Harata Yoshitaka Fujii | 2007 | Oncology Reports2007，，： | 1 |
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