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| 1 | Milan criteria are useful predictors for favorable outcomes in hepatocellular carcinoma patients undergoing liver transplantation after transarterial chemoembolization显示文摘AIM: To evaluate whether the Milan criteria are useful in patients with hepatocellular carcinoma (HCC) who received transarterial chemoembolization (TACE) before liver transplantation (LT). METHODS: Thirty-six HCC patients who fulfilled the Milan criteria after having received TACE and subsequently underwent LT were included (TACE + LT group) in the study. As controls, 21 patients who also met the Milan criteria and underwent LT without prior treatment were selected (LT group). Post-LT clinical outcomes, such as HCC recurrence, survival rate, and histologic features of explanted livers, were compared between the two groups. RESULTS: Baseline characteristics were not different between the two groups. Pre-LT maximal tumor diameter in TACE + LT group was similar to that of LT group (2.0 ± 0.6 cm vs 2.3 ± 0.9 cm; P = 0.10). Post-LT histologic findings also revealed similar maximal tumor diameter in the two groups (2.4 ± 1.4 cm vs 2.3 ± 0.9 cm; P = 0.70). Explanted livers showed similar incidence of unfavorable pathologic features. The morality within 60 d after transplantation was not different between the two groups (8.3% vs 9.5%; P = 0.99). Post-LT 5-year survival rate (57% vs 74%; P = 0.70) and cumulative recurrence rate (8.3% vs 4.8%; P = 0.90) were not significantly different between the two groups. CONCLUSION: The Milan criteria are still a useful selec- tion criteria showing favorable outcomes in HCC patientsreceiving TACE before LT. | Do Young Kim Moon Seok Choi Joon Hyoek Lee Kwang Cheol Koh Seung Woon Paik Byung Chul Yoo Sung Wook Shin Sung Wook Choo Young Soo Do Jong Chul Rhee | 2006 | World Journal of Gastroenterology2006，12，43： | 4 |
| 2 | Clinicopathologic features and prognosis of combined hepatocellular cholangiocarcinoma显示文摘 | Kwang Cheol Koh Hyuk Lee Moon Seok Choi Joon Hyoek Lee Seung Woon Paik Byung Chul Yoo Jong Chul Rhee Jae Won Cho Cheol Keun Park Hong Joo Kim | 2005 | The American Journal of Surgery2005，，1： | 2 |
| 3 | Percutaneous radiofrequency ablation for early-stage hepatocellular carcinoma as a first-line treatment: long-term results and prognostic factors in a large single-institution series显示文摘 | Dongil Choi Hyo K. Lim Hyunchul Rhim Young-sun Kim Won Jae Lee Seung Woon Paik Kwang Cheol Koh Joon Hyoek Lee Moon Seok Choi Byung Chul Yoo | 2007 | European Radiology2007，，3： | 2 |
| 4 | A comparison of clevudine and entecavir for treatment-na?ve patients with chronic hepatitis B: results after 2 years of treatment显示文摘 | Geum-Youn Gwak Sung June Eo Su Rin Shin Moon Seok Choi Joon Hyoek Lee Kwang Cheol Koh Seung Woon Paik Byung Chul Yoo | 2013 | Hepatology International2013，，1： | 1 |
| 5 | Radiation therapy for abdominal lymph node metastasis from hepatocellular carcinoma显示文摘 | Young Je Park Do Hoon Lim Seung Woon Paik Kwang Cheol Koh Joon Hyoek Lee Moon Seok Choi Byung Chul Yoo Hee Rim Nam Dong Ryul Oh Won Park Yong Chan Ahn Seung Jae Huh | 2006 | Journal of Gastroenterology2006，，11： | 1 |
| 6 | Analysis of risk factors associated with early multinodular recurrences after hepatic resection for hepatocellular carcinoma显示文摘 | Jung Ho Park Kwang Cheol Koh Moon Suk Choi Joon Hyoek Lee Byung Chul Yoo Seung Woon Paik Jong Chul Rhee Jae Won Joh | 2006 | The American Journal of Surgery2006，，1： | 1 |
| 7 | Long‐term survival after surgical resection for huge hepatocellular carcinoma: Comparison with transarterial chemoembolization after propensity score matching显示文摘 | Yang Won Min Jun Hee Lee Geum‐Youn Gwak Yong Han Paik Joon Hyoek Lee Poong‐Lyul Rhee Kwang Cheol Koh Seung Woon Paik Byung Chul Yoo Moon Seok Choi | 2014 | J Gastroenterol Hepatol2014，，5： | 1 |
| 8 | Effect of Balloon-Occluded Retrograde Transvenous Obliteration on the Natural History of Coexisting Esophageal Varices显示文摘 | Yong Sung Choi Joon Hyoek Lee Dong Hyun Sinn Young Bong Song Geum-Youn Gwak Moon Seok Choi Kwang Cheol Koh Seung Woon Paik Byung Chul Yoo | 2008 | Journal of Clinical Gastroenterology2008，，9： | 1 |
| 9 | A nationwide seroepidemiology of hepatitis C virus infection in South Korea显示文摘 | Do Young Kim In Hee Kim Sook‐Hyang Jeong Yong Kyun Cho Joon Hyoek Lee Young‐Joo Jin Don Lee Dong Jin Suh Kwang‐Hyub Han Neung Hwa Park Ha Yan Kang Young Kul Jung Young Seok Kim Kyung‐Ah Kim Youn Jae Lee Byung Seok Lee Hyung Joon Yim Heon Ju Lee Soon Koo B | 2013 | Liver Int2013，，4： | 1 |
| 10 | Predictive factors of gastroduodenal toxicity in cirrhotic patients after three-dimensional conformal radiotherapy for hepatocellular carcinoma显示文摘 | Haeyoung Kim Do Hoon Lim Seung Woon Paik Byung Chul Yoo Kwang Gheol Koh Joon Hyoek Lee Moon Seok Choi Won Park Hee Chul Park Seung Jae Huh Doo Ho Choi Yong Chan Ahn | 2009 | Radiotherapy and Oncology2009，，2： | 1 |
| 11 | Clinical course of sub-centimeter-sized nodules detected during surveillance for hepatocellular carcinoma显示文摘AIM: To evaluate the outcome of sub-centimeter-sized nodules (SCSNs) detected during surveillance for hepatocellular carcinoma (HCC) in patients at risk. METHODS: We retrospectively analyzed a total of 142 patients with liver cirrhosis or chronic hepatitis B or C without a prior history of HCC in whom a SCSN was detected during HCC surveillance. We calculated the rate of HCC development from SCSNs in the study population and analyzed the differences in the baseline clinical characteristics and imaging features between the patients with SCSNs that eventually developed into HCC and patients with SCSNs that did not develop into HCC.RESULTS: During 667 person-years of follow-up, HCC developed in 33 patients. The calculated HCC development rate was 4.9% per year. The cumulative one-, two-, three- and five-year HCC development rates were 5.6%, 10.6%, 14.1% and 20.4%, respectively. Upon baseline comparison, the HCC group was older (54.4 ± 8.3 years vs 48.9 ± 9.4 years; P = 0.003) and had lower albumin levels (3.56 ± 0.58 g/dL vs 3.84 ± 0.55 g/dL; P = 0.012) and higher baseline alpha-fetoprotein (AFP) levels (8.5 ng/mL vs 5.4 ng/mL; P = 0.035) compared to the non-HCC group. Nodule pattern and initial radiologic diagnosis also differed between the two groups. Multivariate analysis revealed that age [P = 0.012, odds ratio (OR) =1.075, 95% confidence interval (CI) =1.016-1.137], sex (P = 0.009, OR = 3.969, 95% CI: 1.403-11.226), and baseline AFP level (P = 0.024, OR = 1.039, 95% CI: 1.005-1.073) were independent risk factors for developing HCC. CONCLUSION: The overall risk of HCC development in patients with SCSNs is similar to that in liver cirrhosis patients. Patients with these risk factors need to be closely monitored during follow-up. | Yang Won Min Geum-Youn Gwak Min Woo Lee Moon Seok Choi Joon Hyoek Lee Kwang Cheol Koh Seung Woon Paik Byung Chul Yoo | 2012 | World Journal of Gastroenterology2012，18，21： | 0 |
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