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28篇 您的检索式:作者名="Hu,Yufang"
    题名 作者 年代 出处 被引量
1显示文摘Zhang Zhaohui Zhang Huabin Hu Yufang 2010Analytica Chimica ACTA2010,661,2:1
2Selective and sensitive molecularly imprinted sol–gel film-based electrochemical sensor combining mercaptoacetic acid-modified PbS nanoparticles with Fe3O4@Au–multi-walled carbon nanotubes–chitosan显示文摘Yufang Hu Zhaohui Zhang Huabin Zhang Lijuan Luo Shouzhuo Yao 2012Journal of Solid State Electrochemistry2012,,3:1
3Synthesis of a novel composite imprinted material based on multi- walled carbon nanotubes as a selective melamine absorbent 显示文摘Huabin Zhmag Zhaohui Zhang Yufang Hu 2011JAgr/c Food Chera2011,59,:1
4Direct determination of trace cadmium in environmental samples by dynamic reaction cell inductively coupled plasma mass spectrometry显示文摘GUO Wei HU Shenghong XIAO Yufang 2010Chemosphere2010,81,11:1
5Novellayer-by-layer assembly molecularly imprinted sol-gel sensor for selective recognition of clindamycin based on Au electrode decorated by multi-wall carbon nanotube显示文摘Zhang Zhaohui Hu Yufang Zhang Huabin 2010Journal of Colloid and Interface Science2010,344,:1
6Novel surface molecularly imprinted material modified multi-walled carbon nanotubes as solid-phase extraction sorbent for selective extraction gallium ion from fly ash显示文摘Zhang Zhaohui Zhang Huabin Hu Yufang 2010Talanta2010,82,:1
7Synthesis and application of multi-walled carbon nanotubes-molecularly imprinted sol-gel composite material for on-line solid-phase extraction and high - performance liquid chromatography determination of trace Sudan IV显示文摘Zhang Zhaohui Zhang Huabin Hu Yufang 2010Analytica Chimica Acta2010,661,:1
8Current approaches and future directions in the treatment of HER2-positive breast cancer显示文摘Sara A. Hurvitz Yufang Hu Neil O’Brien Richard S. Finn 2012Cancer Treatment Reviews2012,,:1
9Novel molecularly imprinted polymers based on multi-walled carbon nanotubes with binary functional monomer for the solid-phase extraction of erythromycin from chicken muscle显示文摘Zhaohui Zhang Xiao Yang Huabin Zhang Minlei Zhang LiJuan Luo Yufang Hu Shouzhuo Yao 2011Journal of Chromatography B2011,,19:1
10A fluorometric assay for acetylcholinesterase activity and inhibitor detection based on DNA-templated copper/silver nanoclusters显示文摘Wenhua Li Wang Li Yufang Hu Yalin Xia Qinpeng Shen Zhou Nie Yan Huang Shouzhuo Yao 2013Biosensors and Bioelectronics2013,,:1
11Electrochemical Sensor for Sensitive Determination of Ga(III) Ion Based on β-Cyclodextrin Incorporated Multi-walled Carbon Nanotubes and Imprinted Sol-gel Composite Film显示文摘为踪迹镓离子的察觉的一个新奇传感器[Ga (III )] 被一个金电极的逐步的修正与 -cyclodextrin 创造(-CD)/multi-walled 碳 nanotubes (MWCNT ) 和一个离子印了聚合物(IIP ) 。传感器表面形态学被扫描电子显微镜学描绘。印的传感器的电气化学的表演被周期的 voltammetry,微分脉搏 voltammetry 和 chronoamperometry 调查。传感器向目标 Ga (III ) 离子显示了优秀选择。同时,介绍 MWCNT 显示了显著催化活动,并且 CD 表明了重要丰富能力。一条线性刻度曲线被获得从 5.0Hu,Yufang Zhang,Zhaohui Zhang,Huabin Luo,Lijuan Zhang,Minglei Yang,Xiao Yao,Shouzhuo 2012Chinese Journal of Chemistry2012,30,2:2
12Optimization of protoplast isolation,transformation and its application in sugarcane (Saccharum spontaneum L.)显示文摘Sugarcane is a prominent source of sugar and ethanol production.Genetic analysis for trait improvement of sugarcane is greatly hindered by its complex genome,long breeding cycle,and recalcitrance to genetic transformation.The protoplast-based transient transformation system is a versatile and convenient tool for in vivo functional gene analysis;however,quick and effective transformation systems are still lacking for sugarcane.Here,we developed an efficient protoplast-based transformation system by optimizing conditions of protoplasts isolation and PEG-mediated transformation in S.spontaneum.The yield of viable protoplasts was approximately 1.26×107 per gram of leaf material,and the transformation efficiency of 80.19%could be achieved under the optimized condition.Furthermore,using this approach,the nuclear localization of an ABI5-like bZIPs transcription factor was validated,and the promoter activity of several putative DNase I hypersensitive sites(DHSs)was assessed.The results indicated this system can be conveniently applied to protein subcellular localization and promoter activity assays.A highly efficient S.spontaneum mesophyll cell protoplast isolation and transient transformation method was developed,and it shall be suitable for in vivo functional gene analysis in sugarcane.Qiongli Wang Guangrun Yu Zhiyong Chen Jinlei Han Yufang Hu Kai Wang 2021The Crop Journal2021,9,1:1
13Robust Trajectory and Communication Design for Angle-Constrained Multi-UAV Communications in the Presence of Jammers显示文摘This paper studies a multi-unmanned aerial vehicle(UAV)enabled wireless communication system,where multiple UAVs are employed to communicate with a group of ground terminals(GTs)in the presence of potential jammers.We aim to maximize the throughput overall GTs by jointly optimizing the UAVs’trajectory,the GTs’scheduling and power allocation.Unlike most prior studies,we consider the UAVs’turning and climbing angle constraints,the UAVs’three-dimensional(3D)trajectory constraints,minimum UAV-to-UAV(U2U)distance constraint,and the GTs’transmit power requirements.However,the formulated problem is a mixed-integer non-convex problem and is intractable to work it out with conventional optimization methods.To tackle this difficulty,we propose an efficient robust iterative algorithm to decompose the original problem be three sub-problems and acquire the suboptimal solution via utilizing the block coordinate descent(BCD)method,successive convex approximation(SCA)technique,and S-procedure.Extensive simulation results show that our proposed robust iterative algorithm offers a substantial gain in the system performance compared with the benchmark algorithms.Yufang Gao Yang Wu Zhichao Cui Wendong Yang Guojie Hu Shiming Xu 2022China Communications2022,19,2:1
14N-acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4-acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) mRNA显示文摘Background:N-acetyltransferase 10(NAT10)is the only enzyme known tomediate the N4-acetylcytidine(ac4C)modification of mRNA and is crucial formRNA stability and translation efficiency.However,its role in cancer development and prognosis has not yet been explored.This study aimed to examine the possible role of NAT10 in colon cancer.Methods:The expression levels ofNAT10were evaluated by immunohistochemical analyses with a colon cancer tissue microarray,and its prognostic value in patients was further analyzed.Quantitative real-time polymerase chain reaction(qRT-PCR)and Western blotting were performed to analyze NAT10 expression in harvested colon cancer tissues and cell lines.Stable NAT10-knockdown and NAT10-overexpressing colon cancer cell lines were constructed using lentivirus.The biological functions of NAT10 in colon cancer cell lines were analyzed in vitro by Cell Counting Kit-8(CCK-8),wound healing,Transwell,cell cycle,and ferroptosis assays.Xenograft models were used to analyze the effect of NAT10 on the tumorigenesis and metastasis of colon cancer cells in vivo.Dot blotting,acetylated RNA immunoprecipitation-qPCR,and RNA stability analyses were performed to explore the mechanism by which NAT10 functions in colon cancer progression.Results:NAT10 was upregulated in colon cancer tissues and various colon cancer cell lines.This increased NAT10 expression was associated with shorter patient survival.Knockdown of NAT10 in two colon cancer cell lines(HT-29 and LoVo)impaired the proliferation,migration,invasion,tumor formation and metastasis of these cells,whereas overexpression of NAT10 promoted these abilities.Further analysis revealed that NAT10 exerted a strong effect on the mRNA stability and expression of ferroptosis suppressor protein 1(FSP1)in HT-29 and LoVo cells.In these cells,FSP1 mRNA was found to be modified by ac4C acetylation,and this epigenetic modification was associated with the inhibition of ferroptosis.Conclusions:Our study revealed that NAT10 plays a critical role in colon cancer development by affecting FSP1 mRNA stability and ferroptosis,suggesting that NAT10 could be a novel prognostic and therapeutic target in colon cancer.Xiao Zheng Qi Wang You Zhou Dachuan Zhang Yiting Geng Wenwei Hu Changping Wu Yufang Shi Jingting Jiang 2022Cancer Communications2022,42,12:3
15Molecular identification of Echinococcus species from eastern and southern Qinghai, China, based on the mitochondrial cox1 gene显示文摘Junying Ma Hu Wang Gonghua Lin Philip S. Craig Akira Ito Zhenyuan Cai Tongzuo Zhang Xiumin Han Xiao Ma Jingxiao Zhang Yufang Liu Yanmei Zhao Yongshun Wang 2012Parasitology Research2012,,1:2
16A novel approach to Finafloxacin hydrochloride (BAY35-3377)显示文摘Jian Hong Zonghua Zhang Huoxing Lei Haiying Cheng Yufang Hu Wanliang Yang Yinglin Liang Debasis Das Shu-Hui Chen Ge Li 2009Tetrahedron Letters2009,,21:1
17Evidence-based medication use among Chinese patients with acute coronary syndromes at the time of hospital discharge and 1 year after hospitalization: Results from the Clinical Pathways for Acute Coronary Syndromes in China (CPACS) study显示文摘Yufang Bi Runlin Gao Anushka Patel Steve Su Wei Gao Dayi Hu Dejia Huang Lingzhi Kong Wenhang Qi Yangfeng Wu Yuejin Yang Fiona Turnbull 2009American Heart Journal2009,,3:1
18Responses of the East Component of Beijing GNSS Continuous Observation Stations to the 2011 Japan M_W 9.0 Earthquake显示文摘Several new demands have been put forward for the application of the Beijing continuous GNSS observations due to some particular reasons,such as the limited coverage of the observation network,the different construction and management criterion executed by different units and the intense interference resulting from human activity. In this paper,necessary processing of data is carried out, including more accurate calculation,corrections to the replacement,outliers and relocation of equipment,and elimination of linear trends in the E-component for every station. The E-components of the 16 available stations showed a lower sawtooth wave anomaly( s lowly westward propagating) b efore the2011 Tohoku M W9. 0 earthquake,a coseismic step rebound( rapid eastward propagating)and a post-seismic Ω-shaped recovery. These steps constituted a complete earthquake process which was rarely seen before in the GNSS observations and provides a good example for further study. Moreover, t he rapid eastward propagating during the earthquake is not influenced by the size of the given normal values,which may play a significant role in earthquake forecasting and early warning.Wu Peizhi Sun Jianbao Xu Ping Xing Chengqi Hu Leyin Liang Fang Huang Yurui Shi Yufang Ji Hong 2015Earthquake Research in China2015,29,2:0
19Mesenchymal stem cells: a new strategy for immunosuppression and tissue repair显示文摘间充质的干细胞(MSC ) 为治疗各种各样的疾病有大潜力,特别那些与织物有关损坏包含有免疫力的反应。各种各样的研究证明了 MSC 在 vitro 并且在 vivo 是强烈抑制免疫力的。我们的最近的研究证明了那未刺激的 MSC 确实不能免疫力的抑制;他们与 TNF- 伪, IL-1 伪或 IL-1 尾与激活的淋巴细胞的上层清液,或与 IFN- 纬的联合在刺激之上变得 potently 抑制免疫力。这观察表明在某些情形下面,煽动性的 cytokines 能实际上变得抑制免疫力。我们证明在调停 MSC 的免疫力的抑制的机制有一个种类变化:由告知 cytokine 的老鼠 MSC 的免疫力的抑制被氮的氧化物调停(没有) 而由告知 cytokine 的人的 MSC 的免疫力的抑制通过 indoleamine 被执行 2, 3-dioxygenase (伊多语) 。在有煽动性的 cytokines 的刺激之上,另外,老鼠和人的 MSC 分泌几白血球 chemokines 显然服务与 MSC 吸引有免疫力的房间进最近,在哪儿不或伊多语被预言很活跃。因此,由煽动性的刺激 cytokine 的 MSC 的免疫力的抑制经由 chemokines 的一致行动发生并且免疫者禁止没有或伊多语由 MSC 生产了。因此,我们的结果在对待有免疫力的回答导致的织物损害关于调停 MSC 的免疫力的抑制并且为 MSC 的更好的申请的机制提供新奇信息。Yufang Shi Gangzheng Hu Juanjuan Su Wenzhao Li Qing Chen Peishun Shou Chunliang Xu Xiaodong Chen Yin Huang Zhexin Zhu Xin Huang Xiaoyan Han Ningxia Xie Guangwen Ren 2010Cell Research2010,20,5:72
20GSDMB promotes non-canonical pyroptosis by enhancing caspase-4 activity显示文摘Gasdermin B (GSDMB) has been reported to be associated with immune diseases in humans, but the detailed molecular mechanisms remain unsolved. The N-terminus of GSDMB by itself, unlike other gasdermin family proteins, does not induce cell death. Here, we show that GSDMB is highly expressed in the leukocytes of septic shock patients, which is associated with increased release of the gasdermin D (GSDMD) N-terminus. GSDMB expression and the accumulation of the N-terminal fragment of GSDMD are induced by the activation of the non-canonical pyroptosis pathway in a human monocyte cell line. The downregulation of GSDMB alleviates the cleavage of GSDMD and cell death. Consistently, the overexpression of GSDMB promotes GSDMD cleavage, accompanied by increased LDH release. We further found that GSDMB promotes caspase-4 activity, which is required for the cleavage of GSDMD in non-canonical pyroptosis, by directly binding to the CARD domain of caspase-4. Our study reveals a GSDMB-mediated novel regulatory mechanism for non-canonical pyroptosis and suggests a potential new strategy for the treatment of inflammatory diseases.Qin Chen Peiliang Shi Yufang Wang Dayuan Zou Xiuwen Wu Dingyu Wang Qiongyuan Hu Yujie Zou Zan Huang Jianan Ren Zhaoyu Lin Xiang Gao 2019Journal of Molecular Cell Biology2019,11,6:22
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