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| 1 | Gastric emptying, postprandial blood pressure, glycaemia and splanchnic flow in Parkinson's disease显示文摘AIM: To determine gastric emptying, blood pressure, mesenteric artery blood flow, and blood glucose responses to oral glucose in Parkinson's disease. METHODS: Twenty-one subjects(13 M, 8 F; age 64.2 ± 1.6 years) with mild to moderate Parkinson's disease(Hoehn and Yahr score 1.4 ± 0.1, duration of known disease 6.3 ± 0.9 years) consumed a 75 g glucose drink, labelled with 20 MBq 99mTc-calcium phytate. Gastric emptying was quantified with scintigraphy, blood pressure and heart rate with an automated device, superior mesenteric artery blood flow by Doppler ultrasonography and blood glucose byglucometer for 180 min. Autonomic nerve function was evaluated with cardiovascular reflex tests and upper gastrointestinal symptoms by questionnaire. RESULTS: The mean gastric half-emptying time was 106 ± 9.1 min, gastric emptying was abnormally delayed in 3 subjects(14%). Systolic and diastolic blood pressure fell(P < 0.001) and mesenteric blood flow and blood glucose(P < 0.001 for both) increased, following the drink. Three subjects(14%) had definite autonomic neuropathy and 8(38%) had postprandial hypotension. There were no significant relationships between changes in blood pressure, heart rate or mesenteric artery blood flow with gastric emptying. Gastric emptying was related to the score for autonomic nerve function(R = 0.55, P < 0.01). There was an inverse relationship between the blood glucose at t = 30 min(R =-0.52, P < 0.05), while the blood glucose at t = 180 min was related directly(R = 0.49, P < 0.05), with gastric emptying. CONCLUSION: In mild to moderate Parkinson's disease, gastric emptying is related to autonomic dysfunction and a determinant of the glycaemic response to oral glucose. | Laurence G Trahair Thomas E Kimber Katerina Flabouris Michael Horowitz Karen L Jones | 2016 | World Journal of Gastroenterology2016，22，20： | 5 |
| 2 | Whey protein: The “whey” forward for treatment of type 2 diabetes?显示文摘A cost-effective nutritional approach to improve postprandial glycaemia is attractive considering the rising burden of diabetes throughout the world. Whey protein, a by-product of the cheese-making process, can be used to manipulate gut function in order to slow gastric emptying and stimulate incretin hormone secretion, thereby attenuating postprandial glycaemic excursions. The function of the gastrointestinal tract plays a pivotal role in glucose homeostasis, particularly during the postprandial period, and this review will discuss the mechanisms by which whey protein slows gastric emptying and stimulates release of gut peptides, including the incretins. Whey protein is also a rich source of amino acids, and these can directly stimulate beta cells to secrete insulin, which contributes to the reduction in postprandial glycaemia. Appetite is suppressed with consumption of whey, due to its effects on the gut-brain axis and the hypothalamus. These properties of whey protein suggest its potential in the management of type 2 diabetes. However, the optimal dose and timing of whey protein ingestion are yet to be defined, and studies are required to examine the long-term benefits of whey consumption for overall glycaemic control. | Linda E Mignone Tongzhi Wu Michael Horowitz Christopher K Rayner | 2015 | World Journal of Diabetes2015，6，14： | 2 |
| 3 | Divide-and-conquer for parallel processing显示文摘 | Horowitz E Zorat A | 1983 | IEEE Trans Computer1983，32，： | 2 |
| 4 | Awareness, self-management behaviors, health literacy and kidney function relationships in specialty practice显示文摘AIM To determine the relationship between chronic kidney disease(CKD) awareness(CKD-A), self-management behaviors(CKD-SMB) knowledge, performance of CKDSMBs, health literacy(HL) and kidney function. METHODS Participants were eligible patients attending an outpatient nephrology clinic. Participants were administered: Newest Vital Sign to measure HL, CKD self-managementknowledge tool(CKD-SMKT) to assess knowledge, past performance of CKD-SMB, CKD-A. Estimated GFR(e GFR) was determined using the MDRD-4 equation. Duration of clinic participation and CKD cause were extracted from medical charts. RESULTS One-hundred-fifty patients participated in the study. e GFRs ranged from 17-152 m L/min per 1.73 m2. Majority(83%) of respondents had stage 3 or 4 CKD, low HL(63%), and were CKD aware(88%). Approximately 40%(10/25) of patients in stages 1 and 2 and 6.4%(8/125) in stages 3 and 4 were unaware of their CKD. CKD-A differed with stage(P < 0.001) but not by HL level, duration of clinic participation, or CKD cause. Majority of respondents(≥ 90%) correctly answered one or more CKD-SMKT items. Knowledge of one behavior, 'controlling blood pressure' differed significantly by CKD-A. CKD-A was associated with past performance of two CKD-SMBs, 'controlling blood pressure'(P = 0.02), and 'keeping healthy body weight'(P = 0.01). Adjusted multivariate analyses between CKD-A and:(1) HL; and(2) CKD-SMB knowledge were nonsignificant. However, there was a significant relationship between CKD-A and kidney function after controlling for demographics, HL, and CKD-SMB(P < 0.05). CONCLUSION CKD-A is not associated with HL, or better CKD-SMBs. CKD-A is significantly associated with kidney function and substantially lower e GFR, suggesting the need for focused patient education in CKD stages 1. | Radhika Devraj Matthew E Borrego A Mary Vilay Junvie Pailden Bruce Horowitz | 2018 | World Journal of Nephrology2018，7，1： | 2 |
| 5 | Effect of donor–recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis显示文摘 | Mary Eapen John P Klein Guillermo F Sanz Stephen Spellman Annalisa Ruggeri Claudio Anasetti Maria Brown Richard E Champlin Joan Garcia-Lopez Gareth Hattersely Gesine Koegler Mary J Laughlin Gerard Michel Samir K Nabhan Franklin O Smith Mary M Horowitz Eli | 2011 | Lancet Oncology2011，，13： | 2 |
| 6 | Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis显示文摘 | Mary Eapen Vanderson Rocha Guillermo Sanz Andromachi Scaradavou Mei-Jie Zhang William Arcese Anne Sirvent Richard E Champlin Nelson Chao Adrian P Gee Luis Isola Mary J Laughlin David I Marks Samir Nabhan Annalisa Ruggeri Robert Soiffer Mary M Horowitz Eli | 2010 | Lancet Oncology2010，，7： | 2 |
| 7 | Chronic insomnia and cognitive functioning among older aduhs显示文摘 | Haimov I Hanuka E Horowitz Y | 2008 | Behav Sleep Med2008，，： | 1 |
| 8 | Quasinormal modes of AdS black holes and the approach to thermal equilibrium显示文摘 | HOROWITZ G T HUBENY V E | 2000 | Phys Rev D2000，62，02： | 1 |
| 9 | Measuring motivations for online opinion seeking显示文摘 | Goldsmith R E Horowitz D | 2006 | Journal of Interactive Advertising2006，6，2： | 1 |
| 10 | Rupture of intracranial aneurysms during endovascular coiling: management and outcomes显示文摘 | Levy E Koebbe CJ Horowitz MB | 2001 | Neurosurgery2001，49，： | 1 |
| 11 | Differen- tial expression and localization of de-novo synthesized endometfiotic haptoglobin in endometrium and endometfiotic lesions 显示文摘 | Sharpe-Timms K L Rieke E A Piva M Horowitz G M | 2000 | Hum Reprod2000，15，10： | 1 |
| 12 | Computing Partitions with Applications to Knapsack Problem显示文摘 | Horowitz E Sahni S | | 0，，02： | 1 |
| 13 | 放射性肠炎显示文摘肠遭损伤常为腹部或盆腔的放射治疗结局之一而出现,而慢性放射性肠炎又是使发病率和死亡率增加的一个重要原因,本文重点就放射性肠炎治疗和预防的进展作一综述。症状及发病情况1.急性放射性肠炎在盆腔和/或腹部的放射治疗过程中,急性放射性肠炎在临床上常表现为伴有腹部痉挛(或无痉挛)的腹泻,它的发生几乎是无法避免的,这些症状常在盆腔常规放疗中的第3周出现。恶心和呕吐亦常发生,特别是在全腹部照射时。急性放射性肠炎一般在放疗后6周得到明显改善,但约20%的病人由于症状严重, | E Yeoh M Horowitz 梁永 | 1990 | 国外医学(肿瘤学分册)1990，17，3： | 1 |
| 14 | Hysteroscopy combined with hysterosalpingo contrast sonography (HycoSy) : a new modality for comprehensive of the female pelvic organs 显示文摘 | Horowitz E Orrvieto R Rabinerson D | 2006 | Gynecol Endocrinol2006，22，： | 1 |
| 15 | Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells 显示文摘 | Horowitz JM Park SH Bogenmann E | 1990 | Proc Natl Acad Sci USA1990，87，7： | 1 |
| 16 | Circuits and techniques for high-iesolution measurement of on-chip power supply noise 显示文摘 | Alon E Stojanovic V Horowitz M A | 2005 | IEEE Journal of Solid-State Circuits2005，40，4： | 1 |
| 17 | A retrospective study of the effects of pelvic irradiation for carcinoma of the cervix on gastrointestinal function显示文摘 | Yeoh E Horowitz M Russo A | 1993 | Int J Radiat Oncol Biol Phys1993，26，2： | 1 |
| 18 | Fairness in simple bargaining games显示文摘 | Forsythe R Horowitz J L Savin N E | 1994 | Games and Economic Behavior1994，，6： | 1 |
| 19 | Hepatic undifferentiated(embryonal)sarcoma and rhabdomyosarcoma in children:Results of therapy显示文摘 | Horowitz M E Etcubanas E Webber B L | 1987 | Cancer1987，59，： | 1 |
| 20 | Hysteroscopy combined with hysterosalpingo cont rast sonography (HyCoSy):a new modality for comprehensive evaluation of the female pelvic organs 显示文摘 | Horowitz E Orvieto R Rabinerson D | 2006 | Gynecol Endocrinol2006，22，： | 1 |
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