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| 1 | 不同地域患者罗库溴铵药效学的比较——多中心研究显示文摘目的比较中国、奥地利和美国3个不同地域的当地患者罗库溴铵作用的量效关系和时效关系。方法选择中国大连、美国英格伍德、奥地利格拉茨3个医学中心择期手术患者各18例,异丙酚、芬太尼静脉麻醉诱导后,累积剂量法进行药效学观察,首剂静脉注射罗库溴铵50μg/kg,起效后重复首剂静脉给药6次,再静脉注射罗库溴铵300μg,采用肌机械运动监测仪记录肌肉收缩强度,对数剂量.概率单位绘制剂量-反应曲线。比较3个地域患者罗库溴铵的ED50、ED90和ED95以及Dur25和Dur0.8。结果大连和格拉茨患者罗库溴铵的ED50、ED90和ED95均高于英格伍德患者,格拉茨患者的ED50、ED90和ED95高于大连患者(P<0.05);大连和格拉茨患者的Dur25和Dur0.8均短于英格伍德患者(P<0.05),格拉茨患者的Dur25短于大连患者(P<0.05),但两者Dur0.8的差异无统计学意义(P>0.05)。结论3个地域患者罗库溴铵作用的量效关系和时效关系有明显的差别,临床用量需要考虑地域因素的影响。 | 安刚 肖昭扬 李宝珠 黄磷 魏芳 Ashnaf A. Dahaba Henry Bennett Aryeh Shander Helfried Metzler Peter H. Rehak | 2007 | 中华麻醉学杂志2007，27，3： | 7 |
| 2 | Complex pattern of colon cancer recurrence including a kidney metastasis: A case report显示文摘We report a case of a 77-year-old female with a local recurrence of cancer after right hemicolectomy which infiltrated the pancreatic head affording pancreatoduodenectomy, who developed 3 years later recurrent tumor masses localized in the mesentery of the jejunum and in the lower pole of the left kidney. Partial nephrectomy and a segment resection of the small bowel were performed. Histological examination of both specimens revealed a necrotic metastasis of the primary carcinoma of the colon. Although intraluminal implantation of colon cancer cells in the renal pelvic mucosa from ureteric metastasis has been described, metastasis of a colorectal cancer in the kidney parenchyma is extremely rare and can be treated in an organ preserving manner. A complex pattern of colon cancer recurrence with unusual and rare sites of metastasis is reported. | Helfried Waleczek Moritz N Wente Jürgen Kozianka | 2005 | World Journal of Gastroenterology2005，11，35： | 2 |
| 3 | The application of TRT-True reflection tomography at the unterwald tunnel 显示文摘 | Richard O Edward B Helfried B | 2002 | Geophysics2002，，2： | 1 |
| 4 | The Application of TRT-Ture Reflection Tomography at the Unterwald Tunnel显示文摘 | Edward Button Helfried Bretterebner | 2002 | Geophysics2002，67，2： | 1 |
| 5 | Crosslinking of epiehlorohydrin elastomers显示文摘 | Helfried E | 1985 | Rubber World1985，192，2： | 1 |
| 6 | The Application of TRT-True Reflection Tomography- at the Unterwald Tunnel显示文摘 | Richard O Edward B Helfried B | 2002 | Geophysics2002，2，： | 1 |
| 7 | The Application of TRT-True Reflection Tomography at the Unterwald Tunnel显示文摘 | Richard O Edward B Helfried B | 2002 | Geophysics2002，77，2： | 1 |
| 8 | The Effect of Different Stages of Neuromuscular Block on the Bispectral Index and the Bispectral Index-XP Under Remifentanil/Propofol Anesthesia显示文摘 | Ashraf A. Dahaba Markus Mattweber Andreas Fuchs Wilhelm Zenz Peter H. Rehak Werner F. List Helfried Metzler | 2004 | Anesthesia & Analgesia2004，，3： | 1 |
| 9 | Crosslinking of epichlorohydrin elastomers显示文摘 | Helfried Ehrend Rhein-Chmie | 1985 | Rubber World1985，190，5： | 1 |
| 10 | Attention and working memory as predictors of intelligence显示文摘 | Karl S Helfried M | 2004 | Intelligence2004，，： | 1 |
| 11 | Deuterium excess in precipitation of Alpine regions - moisture recycling显示文摘 | Klaus Froehlich Martin Kralik Wolfgang Papesch Dieter Rank Helfried Scheifinger Willibald Stichler | 2008 | Isotopes in Environmental and Health Studies2008，，1： | 1 |
| 12 | Solar shadows显示文摘 | Bletterie Benoit Brunner Helfried | 2006 | IET Power Engineer2006，20，1： | 1 |
| 13 | Chemical composition and biocompatibility of Ti-Ag-O films prepared by ion beam assisted deposition显示文摘 | Wang Xianghui Prokert Friedrich Reuther Helfried | 2004 | Surface &Coatings Technology2004，185，： | 1 |
| 14 | A convenient synthesis of benzonitriles via electrophilic cyanation w ith N-cyanobenzimidazole显示文摘 | PAZHAMALAI A HELFRIED N MATTHIAS B | 2010 | Chem Eur J2010，16，16： | 1 |
| 15 | Crosslinking of epichlorohydrin elastomers显示文摘 | Helfried Ehrend Rhein-chmie | | 0，，： | 1 |
| 16 | Does a change in obstetric management influence the incidence of traumatic birth lesions in mature, otherwise healthy newborn infants 显示文摘 | Willibald Z Josef H Helfried R | 2007 | J Obstet Gynaecol Res2007，33，4： | 1 |
| 17 | Palladium-cata- lyzed carbonylation reactions of alkenes and alkynes 显示文摘 | Anne B Helfried N Matthias B | 2009 | Chem Cat Chem2009，，1： | 1 |
| 18 | Chemical composition and biocompatibility of Ti-Ag-O films prepared by ion beam assisted deposition显示文摘 | Friedrich Prokert Helfried Reuther | 2004 | Surface and Coatings Technology2004，185，： | 1 |
| 19 | Crosslinking of epichlorohy drinelastomers 显示文摘 | Helfried Ehrend Rhein-Chmie | 1985 | Rubber World1985，190，5： | 1 |
| 20 | Novel mutation in the TOR1A (DYT1) gene in atypical, early onset dystonia and polymorphisms in dystonia and early onset parkinsonism显示文摘 | Joanne Leung Christine Klein Jennifer Friedman Peter Vieregge Helfried Jacobs Dana Doheny Christoph Kamm Deborah DeLeon Peter P. Pramstaller John B. Penney Marvin Eisengart Joseph Jankovic Thomas Gasser Susan B. Bressman David P. Corey Patricia Kramer Mit | 2001 | Neurogenetics2001，，3： | 1 |
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