|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 2 | The naturalhistory of primary dysmen orrhea:a longitudinal study显示文摘 | Weismann A M Hartz A J Hansen M D | 2004 | Br J Obstet Gynaecol2004，111，4： | 1 |
| 3 | Differemial interacting of glimepiride with the beta cell sulfonylurea receptor 显示文摘 | Miieller G Hartz D Punter J Koh H Akiyama Yui K | 2004 | Biochim Bio - phys Acta2004，1191，： | 1 |
| 4 | Novel glimepiride derivatives with potential as double-edged swords against type II diabetes显示文摘 | Müller G Schulz A Hartz D | 2010 | Arch Physiol Biochem2010，116，1： | 1 |
| 5 | Basin modelling of a transform margin setting: Structural, thermal and hydrocar bon evolution of the Tano Basin, Ghana显示文摘 | Rupke L Schmid D Hartz E | 2010 | Petroleum Geo science2010，16，3： | 1 |
| 6 | Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier显示文摘 | Bauer B Hartz A M Miller D S | | 0，，03： | 1 |
| 7 | Role of halogen(I)cation-transfer mechanisms in water chlorination in the presence of bromide ion显示文摘 | Margerum D W Hartz K E H | 2002 | Journal of Environmental Monitoring2002，4，1： | 1 |
| 8 | Composted green waste as a container medium amendment for the production of ornamental plants显示文摘 | BURGER D W HARTZ T K FORISTER G W | 1997 | HortScience1997，32，1： | 1 |
| 9 | Mortality study of 18 000 patients treated with omeprazole显示文摘 | Bateman DN Colin-Jones D Hartz S Langman M Logan RF Mant J | 2003 | Gut2003，52，： | 1 |
| 10 | Bronchial airflow limitation,smoking,body mass index,and statin use are strongly associated with the C-reactive protein level in the elderly显示文摘 | MELBYE H HALVORSEN D S HARTZ I | 2007 | Respir Med2007，101，12： | 1 |
| 11 | Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier显示文摘 | Bauer B Hartz A M S Fricker G Miller D S | 2004 | Mol Pharmacol2004，66，： | 1 |
| 12 | Composted green waste as a container medium amendment for the production of ornamental plants显示文摘 | Burger D W Hartz T K Forister G W | 1997 | HortScience1997，32，1： | 1 |
| 13 | Relationship of body fat distribution to blood pressure, carbohydrate tolerance,and plasma lipids in healthy obese women显示文摘 | KALKHOFF R K HARTZ A H RUPLEY D | 1983 | J Lab Clin Med1983，102，： | 1 |
| 14 | Relationship of body fat distribution to blood pressure,carbohydrate tolerance,and plasma lipids in healthy obese women显示文摘 | Kalkhoff RK Hartz AH Rupley D | 1983 | J Lab Clin Med1983，102，4： | 1 |
| 15 | Mechanisms of unexplained anemia in the nursing home 显示文摘 | HARTZ A S H HFERGUSSON D H HDRINKA P J H | 2004 | HJ Am Geriatr Soe2004，52，3： | 1 |
| 16 | Use of soil solarization to control fu sarium wilt of watermelon显示文摘 | Martyn R D Hartz T K | 1986 | Plant Disease1986，70，8： | 1 |
| 17 | Use of soil soilarization to control Fusarium wilt of watermelon显示文摘 | Martyn R D Hartz T K | 1986 | Plant Disease1986，70，8： | 1 |
| 18 | Evaluating the cost effectiveness of donepezil in the treatment of Alzheimer's disease in Germany using discrete event simulation显示文摘 | Hartz S Getsios D Tao S | 2012 | BMC Neurol2012，，12： | 1 |
| 19 | Selection of the initiator tRNA by Escherichia call initiation factors 显示文摘 | Hartz D McPheeters DS Gold L | 1989 | Genes Dev1989，3，12： | 1 |
| 20 | Differential interaction ofglimepride and glibenclamide with theβ-cell sulfonylureareceptorⅠ显示文摘 | Muller G Hartz D Punter J | 1994 | Biochim Biophys Acta1994，91，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员