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| 1 | 在有分散的胃的息肉的病人的 colorectal 息肉的风险: 盒子控制研究显示文摘 AIM:To assess the risk of colonic polyps,adenomas and advanced neoplastic lesions(ANL) in patients with sporadic gastric polyps,especially those with fundic gland polyps(FGP).METHODS:Clinical records of patients who had performed an upper and a lower digestive endoscopy between September 2007 and August 2008 were retrospectively analyzed.A case-control study was carried out,calling patients with gastric polyps as 'cases' and patients without gastric polyps as 'controls'.The risk of colonic polyps,adenomas and ANL(villous component ≥ 25%,size ≥ 10 mm,or high grade dysplasia) was assessed [odds ratio(OR) and its corresponding 95%CI].RESULTS:Two hundred and forty seven patients were analyzed:78 with gastric polyps(cases) and 169 without gastric polyps(controls).Among the cases,the majority of gastric polyps were FGP(80%,CI:69-88) and hyperplastic(20%,CI:12-31);25% had colonic polyps(25% hyperplastic and 68% adenomas,from which 45% were ANL).Among the controls,20% had colonic polyps(31% hyperplastic and 63% adenomas,from which 41% were ANL).The patients with sporadic FGP had an OR of 1.56(CI:0.80-3.04) for colonic polyps,an OR of 1.78(CI:0.82-3.84) for colonic adenomas,and an OR of 0.80(CI:0.21-2.98) for ANL.Similar results were found in patients with gastric polyps in general.CONCLUSION:The results of this study did not show more risk of colorectal adenomas or ANL neither in patients with sporadic gastric polyps nor in those with FGP. | Daniel Gustavo Cimmino José Manuel Mella Pablo Luna Raquel González Lisandro Pereyra Carolina Fischer Adriana Mohaidle Beatriz Vizcaino Mario Andres Medrano Adrián Hadad Silvia Pedreira Luis Boerr | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，5： | 12 |
| 2 | 树轮记录的自公元1200年以来强火山喷发事件与高亚洲南部河流源区气候水文变化的关联显示文摘强火山喷发作为气候变化重要的外强迫因素,其所造成的气候环境效应一直是气候变化研究热点,而其对于流域水循环影响较少受关注。本文利用采自高亚洲南部河流源区麦吊云杉(Picea brachytyla)树轮样本,研制出一个长达885 a的树木年轮标准宽度年表。基于树轮气候响应分析结果,利用线性回归模型重建研究区自公元1200年上年11月至当年2月平均最低气温变化,重建方程方差解释量47.1%。该气温重建序列显示,研究区自公元1200年经历了8个冷期和9个暖期,包含有10个极冷年和23个极暖年。同时,该气温重建序列验证了自公元1200年来27次强火山喷发(VEI≥5)对于青藏高原东南部河流源区气候的影响,包括1257年Samalas和1815年Tambora等强火山喷发事件。该气温重建序列与相关河流径流数据对比结果表明强火山喷发在引起高亚洲南部河流源区气温出现明显下降的同时,也可能会进一步导致水循环减缓,使得高亚洲南部河流径流量出现减少。 | 陈友平 陈峰 张合理 胡茂 王世杰 Hadad Martín ARIEL Roig Junent Fidel ALEJANDRO | 2021 | 第四纪研究2021，41，2： | 12 |
| 3 | 左氧氟沙星、加替沙星及莫西沙星对肺结核患者的早期及延长早期杀菌活性显示文摘目的:评估左氧氟沙星、加替沙星及莫西沙星等新氟喹诺酮类药物对肺结核患者的早期杀菌活性及延长早期杀菌活性。设计:随机开放临床试验。40例成年新诊断的涂阳肺结核患者(每组10例)分别每日单一接受异烟肼300mg,或左氧氟沙星1000mg,或加替沙星400mg,或莫西沙星400mg的7天治疗。治疗前2天及单药治疗7天期间,每日收集痰液进行定量培养。计量单药治疗开始的头2天(0-2天)及治疗后5天(2-7天)的菌量下降情况,以评估各药的早期及延长早期杀菌活性。对实验室工作人员关于病人治疗分组信息采用单盲法。结果:异烟肼的早期杀菌活性为0.67log10cfu/毫升/天,高于莫西沙星(0.33log10cfu/毫升/天)及加替沙星(0.35log10cfu/毫升/天)。与每日1000mg左氧氟沙星的早期杀菌活性(0.45log10cfu/毫升/天)相比,无统计学差异(P=0.14)。3种氟喹诺酮类药物的早期杀菌活性(0-2天)与延长早期杀菌活性(2-7天)相似。总体说来,氟喹诺酮类药物的延长早期杀菌活性高于异烟肼。结论:莫西沙星、加替沙星及高剂量左氧氟沙星,虽然略低于异烟肼,但均有良好的早期杀菌活性,并具有较高的延长早期杀菌活性。有理由对这些药物敏感的结核病人进行进一步的治疗研究。 | J. L. Johnson D. J. Hadad W. H. Boom C. L. Daley C. A. Peloquin K. D. Eisenach D. D. Jankus S. M. Debanne E. D. Charlebois E. Maciel M. Palaci R. Dietzet 马玙(译) 屠德华(校) 张立兴(审) | 2006 | 国际结核病与肺部疾病杂志2006，1，2： | 5 |
| 4 | Intrahepatic HBV DNA as a predictor of antivirus treatment efficacy in HBeAg-positive chronic hepatitis B patients显示文摘AIM: To evaluate the effect of antiviral agents on intrahepatic HBV DNA in HBeAg-positive chronic hepatitis B patients. METHODS: Seventy-one patients received treatment with lamivudine,interferon alpha (IFN-α2b) or sequential therapy with lamivudine-IFN-α2b for 48 wk. All subjects were followed up for 24 wk. Serum and intrahepatic HBV DNA were measured quantitatively by PCR. HBV genotypes were analyzed by PCR-RFLP. RESULTS: At the end of treatment,the intrahepatic HBV DNA level in 71 patients decreased from a mean of (6.1 ± 1.0) log10 to (4.9 ± 1.4) log10. Further,a larger decrease was seen in the intrahepatic HBV DNA level in patients with HBeAg seroconversion. Intrahepatic HBV DNA level (before and after treatment) was not significantly affected by the patients' HBV genotype,or by the probability of virological flare after treatment. CONCLUSION: Intrahepatic HBV DNA can be effectively lowered by antiviral agents and is a significant marker for monitoring antivirus treatment. Low intrahepatic HBV DNA level may achieve better efficacy of antivirus treatment. | Hai-Ying Lu Li-Wei Zhuang Yan-Yan Yu Hadad Ivan Chong-Wen Si Zheng Zeng Jun Li Dong-Ming Hou Xin-Yue Chen Zhong-Hou Han Yong Chen | 2007 | World Journal of Gastroenterology2007，13，20： | 3 |
| 5 | Pancreatic pseudocyst or a cystic tumor of the pancreas?显示文摘Pancreatic pseudocysts are the most common cystic lesions of the pancreas and may complicate acute pancreatitis, chronic pancreatitis, or pancreatic trauma. While the majority of acute pseudocysts resolve spontaneously, few may require drainage. On the other hand, pancreatic cystic tumors, which usually require extirpation, may disguise as pseudocysts. Hence, the distinction between the two entities is crucial for a successful outcome. We conducted this study to highlight the fundamental differences between pancreatic pseudocysts and cystic tumors so that relevant management plans can be devised. We reviewed the data of patients with pancreatic cystic lesions that underwent intervention between June 2007 and December 2010 in our hospital. We identified 9 patients(5 males and 4 females) with a median age of 40 years(range, 30–70 years). Five patients had pseudocysts, 2 had cystic tumors, and 2 had diseases of undetermined pathology. Pancreatic pseudocysts were treated by pseudocystogastrostomy in 2 cases and percutaneous drainage in 3 cases. One case recurred after percutaneous drainage and required pseudocystogastrostomy. The true pancreatic cysts were serous cystadenoma, which was treated by distal pancreatectomy, and mucinous cystadenocarcinoma, which was initially treated by drainage, like a pseudocyst, and then by distal pancreatectomy when its true nature was revealed. We conclude that every effort should be exerted to distinguish between pancreatic pseudocysts and cystic tumors of the pancreas to avoid the serious misjudgement of draining rather than extirpating a pancreatic cystic tumor. Additionally, percutaneous drainage of a pancreatic pseudocyst is a useful adjunct that may substitute for surgical drainage. | Mohammad Ezzedien Rabie Ismail El Hakeem Mohammad Saad Al Skaini Ahmad El Hadad Salim Jamil Mian Tahir Shah Mahmoud Obaid | 2014 | Chinese Journal of Cancer2014，33，2： | 2 |
| 6 | Adipose stromal cells and platelet-rich plasma therapies synergistically increase revascularization during wound healing显示文摘 | BLANTON M W HADAD I JOHNSTONE B H | 2009 | Plast Reconstr Surg2009，123，2： | 1 |
| 7 | Sensitivity of Phytophthora infestans to Mandipropamid and the Effect of Enforeed Selection Pressure in the Field显示文摘 | COHEN Y RUBIN E HADAD T | 2007 | Plant Pathology2007，56，5： | 1 |
| 8 | Population pharmacokinetics of Levofloxacin,Gat- ifloxacin,and moxifloxacin in adults with pulmonary tuberculosis 显示文摘 | PELOQUIN C A HADAD D J MOLINOL P D et al | 2008 | Antimicrob Agents Chemother2008，53，： | 1 |
| 9 | Adipose stromal cells and platelet-rich plasma therapies synergistically increase revascularization during wound healing显示文摘 | Blanton MW Hadad I Johnstone BH | | 0，，2： | 1 |
| 10 | Phosphorous amount in floating and rooted macrophytes growing in wetlands from the Middle Paran'a River floodplain (Argentina) 显示文摘 | Hadad H R Maine M A | 2007 | Ecological engineering2007，31，： | 1 |
| 11 | Determination of two ternary mixtures containing phenobarbitone by second derivative of the ratio spectrum-zero-crossing and HPLC methods显示文摘 | El-Gindy A Emara S Hadad GM | 2003 | Farmaco2003，58，5： | 1 |
| 12 | Investigation on minimum quantity lubricant-MQL grinding of 100Cr6 hardened steel using different abrasive and coolant-lubricant types 显示文摘 | Tawakoli T Hadad M J Sadeghi M H | 2010 | International Journal of Machine Tools & Manufacture2010，50，： | 1 |
| 13 | A novel reconstructive technique after endoscopic expanded endonasal approaches:vascular pedicle nasoseptal flap显示文摘 | Hadad G Bassagasteguy L Carrau RL | 2006 | Laryngoscope2006，116，10： | 1 |
| 14 | Fatal exertional heat stroke:a case series显示文摘 | Rav-Acha M Hadad E Epstein Y | 2004 | Am J Med Sci2004，328，2： | 1 |
| 15 | Calcium absorption,kinetics,bone density,and bone structure in patients with hereditary vitamin D-resistant rickets显示文摘 | Tiosano D Hadad S Chen Z | 2011 | J Clin Endocrinol Metab2011，96，12： | 1 |
| 16 | Recurrent and novel LDL receptor gene mutations causing heterozygous familial hypercholesterolemia in La Habana显示文摘 | Erasmo Pereira Raoul Ferreira Brigitte Hermelin Ginette Thomas Chantal Bernard Véronique Bertrand Hadad Nassiff Dora Mendez Castillo Gilbert Bereziat Pascale Benlian | 1995 | Human Genetics1995，，3： | 1 |
| 17 | Effect of melatonin on intracranial pressure and brain edema following traumatic brain injury:role of oxidative stresses显示文摘 | Dehghan F Khaksari Hadad M Asadikram G | 2013 | Arch Med Res2013，44，4： | 1 |
| 18 | Fractal and multifractal meas- ures of natural and synthetic fracture networks显示文摘 | BERKOWITZ B Hadad A | 1997 | Journal of Geophysical Research B1997，102，12： | 1 |
| 19 | Delay from symptom onset increases the conversion rate in laparoscopic cholecystectomy for acute cholecystitis显示文摘 | Hadad SM Vaidya JS Baker L | 2007 | World J Surg2007，31，6： | 1 |
| 20 | QuikClot Combat Gauze use for hemorrhage control in military trauma: January 2009 Israel Defense Force experience in the Gaza Strip - - a preliminary report of 14 cases 显示文摘 | Ran Y Hadad E Daher S | 2010 | Prehosp Disaster Med2010，25，6： | 1 |
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