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| 1 | Improvement and performance of parallel multilevel fast multipole algorithm显示文摘The method of establishing data structures plays an important role in the efficiency of parallel multilevel fast multipole algorithm(PMLFMA).Considering the main complements of multilevel fast multipole algorithm(MLFMA) memory,a new parallelization strategy and a modified data octree construction scheme are proposed to further reduce communication in order to improve parallel efficiency.For far interaction,a new scheme called dynamic memory allocation is developed.To analyze the workload balancing performance of a parallel implementation,the original concept of workload balancing factor is introduced and verified by numerical examples.Numerical results show that the above measures improve the parallel efficiency and are suitable for the analysis of electrical large-scale scattering objects. | Zhanhe Liu Peilin Huang Zhe Wu Xu Gao | 2011 | Journal of Systems Engineering and Electronics2011，22，1： | 15 |
| 2 | Inhibition of PI3K/Akt/m TOR signaling pathway enhances the sensitivity of the SKOV3/DDP ovarian cancer cell line to cisplatin in vitro显示文摘The activation of the PI3K/AKT/m TOR pathway plays a key role in ovarian cancer tumorigenesis, progression and chemotherapy resistance. This study aimed to explore the possible mechanism that PI-103, a dual inhibitor of phosphatidylinositide 3-kinase and m TOR, enhances the sensitivity of SKOV3/DDP ovarian cancer cell line to cisplatin chemotherapy. The results showed that PI-103 could significantly increase the sensitivity of SKVO3/DDP cells to cisplatin through inhibiting the activation of PI3K/Akt/m TOR signaling pathway and inducing cell cycle arrest and apoptosis. | Yunlang Cai Xiaoqiang Tan Jun Liu Yang Shen Di Wu Mulan Ren Peilin Huang Dandan Yu | 2014 | Chinese Journal of Cancer Research2014，26，5： | 11 |
| 3 | Series expansion feasibility of singular integral in method of moments显示文摘When calculating electromagnetic scattering using method of moments(MoM), integral of the singular term has a significant influence on the results. This paper transforms the singular surface integral to the contour integral. The integrand is expanded to Taylor series and the integral results in a closed form. The cut-off error is analyzed to show that the series converges fast and only about 2 terms can agree well with the accurate result. The comparison of the perfect electric conductive(PEC) sphere's bi-static radar cross section(RCS) using MoM and the accurate method validates the feasibility in manipulating the singularity. The error due to the facet size and the cut-off terms of the series are analyzed in examples. | Jinzu Ji Peilin Huang | 2014 | Journal of Systems Engineering and Electronics2014，25，3： | 9 |
| 4 | Regulating electrolytic Fe_(0.5)CoNiCuZn_(x) high entropy alloy electrodes for oxygen evolution reactions in alkaline solution显示文摘The properties of high entropy alloys(HEAs)depend on their phase structures and compositions.However,it is difficult to control the composition of the HEAs that contain highly volatile metals by the conventional arc melting method.In this paper,homogeneous powdery face centered cubic(FCC)phase Fe_(0.5)CoNiCuZn_(x) HEAs were prepared by the electrolysis of metal oxides in molten Na_(2)CO_(3)-K_(2)CO_(3) using a stable Ni11Fe10Cu inert oxygen-evolution anode.The use of oxide precursors and relatively low synthetic temperature are beneficial to efficiently preparing HEAs that contain highly volatile elements such as Zn.Moreover,the microstructures and compositions of the electrolytic HEAs can be easily tailored by adjusting the components of oxide precursors,then further regulating its properties.Thus,the electrocatalytic activity of Fe_(0.5)Co NiCuZn_(x) HEAs towards oxygen evolution reactions(OER)was investigated in 1 M KOH.The results show that Zn promotes the OER activity of Fe_(0.5)CoNiCuZn_(x) HEAs,i.e.,the HEA(Zn_(0.8))shows the best OER activity exhibiting a low overpotential of 340 m V at 10 m A/cm^(2) and excellent stability of 24 h.Hence,molten salt electrolysis not only provides a green approach to prepare Fe_(0.5)CoNiCuZn_(x) HEAs but also offers an effective way to regulate the structure of the alloys and thereby optimizes the electrocatalytic activities for water electrolysis. | Jian Huang Peilin Wang Peng Li Huayi Yin Dihua Wang | 2021 | Journal of Materials Science & Technology2021，，34： | 4 |
| 5 | High mixing effectiveness lobed nozzles and mixing mechanisms显示文摘For a circular lobed nozzle with the exit plane displaced from the center body,adding a central plug at exit or replacing the nozzle with an alternating-lobe nozzle can improve the mixing effectiveness.In this study,numerical investigations of jet mixing in the lobed nozzles with a central plug and alternating-lobe nozzles in pumping operation were conducted.The effects of the central plugs with the wake ranging from attached to separated flow on the mixing were analyzed,along with the mechanism of improving the mixing performance in a'sword'alternating-lobe nozzle.The simulation results reveal that the large-scale mixing rate,which is dominated by streamwise vortices,is related to the intensity of the attainable heat and mass transfer in the streamwise vortices.The effects of the streamwise vortices on the normal vortex ring are virtually a manifestation of the heat and mass transfer/mixing process of the streamwise vortices.The simulation results also show that the central plug with the attached rear-flow performs better in improving the mixing effectiveness and pumping performance;on the contrary,if the rear-flow is separated,more pressure loss will be induced.In particular,a completely separated flow over the rear of the central plug will severely degrade the attainable heat and mass transfer in the streamwise vortices.For the sword alternating-lobe nozzle,wider sword deep troughs help to increase the flux of the secondary stream around the core region and delay the confluence of the primary stream in the region between the deep and shallow troughs.Thus,the mixing is improved in the middle and posterior segments.Compared to the lobed nozzle with a central plug,the improved sword alternating-lobe nozzle can achieve a higher mixing effectiveness with much less pressure loss,which is preferred in situations when the power loss of the engine is restricted. | SHENG ZhiQiang CHEN ShiChun WU Zhe HUANG PeiLin | 2015 | Science China(Technological Sciences)2015，58，7： | 3 |
| 6 | POWER-AWARE ROUTING BASED ON DSR FOR MOBILE AD HOC NETWORKS显示文摘Energy consumption is a crucial design concern in Mobile Ad hoc NETworks (MANETs) since nodes are powered by batteries with limited energy, whereas Dynamic Source Routing (DSR) protocol does not take the energy limitation of MANET nodes into account. This paper proposes an energy-saving routing algorithm based on DSR: Power Aware Routing protocol based on DSR (PAR-DSR). The design objective of PAR-DSR is to select energy-efficient paths. The main features of PAR-DSR are: (1) Nodes use the Signal Attenuation Rate (SAR) to conduct power control operations; (2) Minimum path cost as metric to balance the traffic and energy consumption of wireless nodes. The simulation results show that PAR-DSR can greatly reduce the energy consumption of MANET nodes. The average node lifetime of PAR-DSR is 50%-77% longer than that of DSR. | Huang Jingbo Hong Peilin Li Jinsheng | 2007 | Journal of Electronics(China)2007，24，2： | 2 |
| 7 | Soluble CD163 and CD163 Expression on Monocytes Associated with Chronic Hepatitis B Inflammation and HBsAg Loss显示文摘Background and Aims:Monocyte/macrophage-associat-ed CD163 is an indicator of the severity of liver inflam-mation and cirrhosis,but the difference of soluble CD163(sCD163)levels in chronic hepatitis B(CHB)patients and hepatitis B surface antigen(HBsAg)-loss patients is un-clear.Herein,we aimed to compare the sCD163 levels in CHB patients and HBsAg-loss patients with or without an-tiviral treatment.Methods:sCD163 and CD163 expres-sion on monocytes were compared among four groups,healthy subjects,treatment-naïve CHB patients,sponta-neous HBsAg-loss patients,and treatment-related HBsAg-loss patients.The correlation between sCD163 levels and clinical parameters in CHB patients was analyzed.A group of 80 patients with hepatitis B virus(HBV)infection and liver biopsy were recruited.Results:sCD163 levels were higher in the CHB group than in the other three groups.sCD163 levels were higher in treatment-related HBsAg-loss patients than in spontaneous HBsAg-loss patients.sCD163 levels were negatively correlated with hepatitis B e-antigen(HBeAg)and HBsAg levels in HBeAg-positive patients.Liv-er biopsy results further demonstrated that sCD163 levels were elevated in CHB patients with substantial inflamma-tion(A≥2)or fibrosis(F≥2).The sCD163 model was more sensitive in predicting inflammation than other noninvasive models.Its levels were higher in patients with normal ala-nine aminotransferase levels and significant inflammation(A≥2)than in patients with no or mild inflammation.Con-clusions:sCD163 and CD163 expression on monocytes were associated with CHB inflammation and HBsAg loss,and may be used as markers to predict HBV-specific im-mune activation. | Peilin Xie Bilian Yao Dao Huang Yongyan Chen Qiming Gong Xinxin Zhang | 2022 | Journal of Clinical and Translational Hepatology2022，10，6： | 2 |
| 8 | Identification and validation of heterotypic cell-in-cell structure as an adverse prognostic predictor for young patients of resectable pancreatic ductal adenocarcinoma显示文摘Dear Editor,Pancreatic ductal adenocarcinoma(PDAC)has a poor prognosis,with an overall 5-year survival rate of less than 10%.Between 20 and 30%of PDAC cases are resectable at diagnosis;however,patients’post-operative survival periods vary widely,irrespective of active therapeutic interventions.1 Therefore,extensive efforts have been made to identify biomarkers that may identify patients with an improved prognosis.Although profound local immune suppression had been implicated in PDAC progression and poor patient survival,a prognostic marker that can directly and functionally read immune evasion in situ is not yet available. | Hongyan Huang Meifang He Yanbin Zhang Bo Zhang Zubiao Niu You Zheng Wen Li Peilin Cui Xiaoning Wang Qiang Sun | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 2 |
| 9 | Enhancement of immunity and disease resistance in the white shrimp, Litopenaeus vannamei, by the probiotic, Bacillus subtilis E20显示文摘 | TSENG Dengyu HO Peilin HUANG Sungyan | 2009 | Fish & Shellfish Immunology2009，26，： | 1 |
| 10 | Fatty Acid Synthase Regulates Proliferation and Migration of Colorectal Cancer Cells Via HER2-PI3K/Akt Signaling Pathway显示文摘 | Nan Li Xiaodong Bu Xiaoqiang Tian Peng Wu Lin Yang Peilin Huang | 2012 | Nutrition and Cancer2012，，6： | 1 |
| 11 | Fatty Acid Synthase Regulates Proliferation and Migration of Colorectal Cancer Cells Via HER2-PI3K/Akt Signaling Pathway显示文摘 | Nan Li Xiaodong Bu Xiaoqiang Tian Peng Wu Lin Yang Peilin Huang | 2012 | Nutrition and Cancer2012，，6： | 1 |
| 12 | The “HER2–PI3K/Akt–FASN Axis” Regulated Malignant Phenotype of Colorectal Cancer Cells显示文摘 | Nan Li Xiaodong Bu Peng Wu Pingping Wu Peilin Huang | 2012 | Lipids2012，，4： | 1 |
| 13 | Design of readout electronics based on peak-holding circuit and multiplexer for a fast neutron spectrometer显示文摘Background Fast neutron detection is meaningful in many research fields such as space environment monitoring.A scintillating fiber array model for fast neutron detection was proposed and developed in 1980s.Aerospace applications of the model require electronics in small size.Purpose To design a dedicated electronic system to readout and process the 384-channel signals from scintillating fiber array,and to use the designed system to fabricate a neutron detector for aerospace applications.Methods With the method of nuclear recoil,fast neutron is detected by tracking recoil proton of n–p scatter in scintillating plastic fibers.Using the peak-holding circuits and multiplexers,the system size and power consumption were reduced.Results The detector fabricated with the designed system,had 34 cm×34 cm×27 cm mechanical size,20.4 kg weight,and 30.05W power consumption.Comparing to traditional waveform sampling electronics,the designed electronics was highly integrated and had a small size.The readout electronics also gave a better energy resolution of 39%in neutron detection,while the energy resolution was 43%in previous version.Conclusion In this study,a highly integrated readout electronic system was designed and verified.The detector using the system gave good performance.The designed electronics had potential development in fast neutron detection and other high energy physics detection system. | Liyang Sun Kai Zhuang Xiaoming Wang Fanjian Zeng Heng An Daowu Li Yuxiong Xue Zhiming Zhang Wei Zhou Yingjie Wang Baotong Feng Peilin Wang Xiaohui Li Jiale Cai Teng Tong Fanhui Meng Junguang Zhou Huan Huang Xuanhou Hu Xiubo Qin | 2018 | Radiation Detection Technology and Methods2018，2，1： | 1 |
| 14 | Electron-ion collider in China显示文摘Lepton scattering is an established ideal tool for studying inner structure of small particles such as nucleons as well as nuclei.As a future high energy nuclear physics project,an Electron-ion collider in China(EicC)has been proposed.It will be constructed based on an upgraded heavy-ion accelerator,High Intensity heavy-ion Accelerator Facility(HIAF)which is currently under construction,together with a new electron ring.The proposed collider will provide highly polarized electrons(with a po-larization of 80%)and protons(with a polarization of 70%)with variable center of mass energies from 15 to 20 GeV and the luminosity of(2–3)×1033 cm^(−2)·s^(−1).Polarized deuterons and Helium-3,as well as unpolarized ion beams from Carbon to Uranium,will be also available at the EicC.The main foci of the EicC will be precision measurements of the structure of the nucleon in the sea quark region,including 3D tomography of nucleon;the partonic structure of nuclei and the parton interaction with the nuclear environment;the exotic states,especially those with heavy flavor quark contents.In addition,issues fundamental to understanding the origin of mass could be addressed by measurements of heavy quarkonia near-threshold production at the EicC.In order to achieve the above-mentioned physics goals,a hermetical detector system will be constructed with cutting-edge technologies.This document is the result of collective contributions and valuable inputs from experts across the globe.The EicC physics program complements the ongoing scientific programs at the Jefferson Laboratory and the future EIC project in the United States.The success of this project will also advance both nuclear and particle physics as well as accelerator and detector technology in China. | Daniele PAnderle Valerio Bertone Xu Cao Lei Chang Ningbo Chang Gu Chen Xurong Chen Zhuojun Chen Zhufang Cui Lingyun Dai Weitian Deng Minghui Ding Xu Feng Chang Gong Longcheng Gui Feng-Kun Guo Chengdong Han Jun He Tie-Jiun Hou Hongxia Huang Yin Huang KrešImir KumeričKi LPKaptari Demin Li Hengne Li Minxiang Li Xueqian Li Yutie Liang Zuotang Liang Chen Liu Chuan Liu Guoming Liu Jie Liu Liuming Liu Xiang Liu Tianbo Liu Xiaofeng Luo Zhun Lyu Boqiang Ma Fu Ma Jianping Ma Yugang Ma Lijun Mao Cédric Mezrag HervéMoutarde Jialun Ping Sixue Qin Hang Ren Craig DRoberts Juan Rojo Guodong Shen Chao Shi Qintao Song Hao Sun PawełSznajder Enke Wang Fan Wang Qian Wang Rong Wang Ruiru Wang Taofeng Wang Wei Wang Xiaoyu Wang Xiaoyun Wang Jiajun Wu Xinggang Wu Lei Xia Bowen Xiao Guoqing Xiao Ju-Jun Xie Yaping Xie Hongxi Xing Hushan Xu Nu Xu Shusheng Xu Mengshi Yan Wenbiao Yan Wencheng Yan Xinhu Yan Jiancheng Yang Yi-Bo Yang Zhi Yang Deliang Yao Zhihong Ye Peilin Yin C-PYuan Wenlong Zhan Jianhui Zhang Jinlong Zhang Pengming Zhang Yifei Zhang Chao-Hsi Chang Zhenyu Zhang Hongwei Zhao Kuang-Ta Chao Qiang Zhao Yuxiang Zhao Zhengguo Zhao Liang Zheng Jian Zhou Xiang Zhou Xiaorong Zhou Bingsong Zou Liping Zou | 2021 | Frontiers of physics2021，16，6： | 1 |
| 15 | Rational design ternary platinum based electrocatalysts for effective methanol oxidation reaction显示文摘Exploring effective, durable, and affordable electrocatalysts of methanol oxidation reaction(MOR) is of vital significance for the industrial application of direct methanol fuel cells. Herein, an efficient, general,and expandable method is developed to synthesis two-dimensional(2D) ternary Pt Bi M nanoplates(NPLs), in which various M(Co, Ni, Cu, Zn, Sn) is severed as the third component to the binary Pt Bi system. The MOR performance of Pt Bi M NPLs is entirely investigated, demonstrating that both the MOR activity and durability is enhanced with the introduction of the additional composition. Pt3Bi3Zn NPLs shows much higher MOR activity and stability than that of the Pt Bi counterparts, not to mention the current advanced Pt Ru/C and Pt/C catalysts. The prominent performances are attributed to the modulated electronic structure of the surface Pt in Pt Bi NPLs by the addition of Zn, resulting in a weakened affination between Pt and the adsorbed poisoning species(mainly CO) compared with Pt Bi NPLs, verified by density functional theory(DFT) calculations. In addition, the absorbed OH can be generated on the surface of Zn atom due to its favorable water activation properties, thus the CO removal on the adjacent Pt atoms is accelerated, further leading to a high activity and anti-poisoning performance of the resulting Pt_(3)Bi_(3)Zn catalyst. This work provides new insights and robust strategy for highly efficient MOR electrocatalyst with extraordinary anti-poisoning performance and stability. | Hao Tian Daoxiong Wu Jing Li Junming Luo Chunman Jia Zhongxin Liu Wei Huang Qi Chen Chong Michael Shim Peilin Deng Yijun Shen Xinlong Tian | 2022 | Journal of Energy Chemistry2022，31，7： | 1 |
| 16 | One-dimensional PtFe hollow nanochains for the efficient oxygen reduction reaction显示文摘Integration of electronic and strain effects with tailored structures is significant to tuning the electrocatalytic activity and stability of the electrocatalysts for the oxygen reduction reaction(ORR).In this study,onedimensional PtFe hollow nanochains are synthesized by a facile and effective method,which exhibit a highly open and porous structure.The modulated electronic and strain effects of Pt atoms are verified by extensive structural characterizations,and the mass and specific activities of the prepared catalyst are roughly 7.45 and 12.44 times higher than those of the commercial Pt/C catalyst,respectively.Remarkably,the catalyst demonstrates robust performance with negligible activity decay after an accelerated durability test for 30,000 cycles.The high activity of the catalyst is probably due to the optimized absorption affinity of Pt-O accelerating the reaction kinetics induced by the cooperation of Fe atoms as well as the unique hollow and curved structures.This study provides new insights into the rational design of high-performance ORR catalysts with considerable durability. | Peng Rao Junming Luo Jing Li Wei Huang Wei Sun Qi Chen Chunman Jia Zhongxin Liu Peilin Deng Yijun Shen Xinlong Tian | 2022 | Carbon Energy2022，4，6： | 0 |
| 17 | Heteroatom dopant strategy triggered high-potential plateau to non-graphitized carbon with highly disordered microstructure for high-performance sodium ion storage显示文摘Non-graphitized carbon(NGC)has been extensively utilized as carbonaceous anode in sodium-ion batteries(SIBs).However,more optimization to achieve competitive capacity and stability is still challenging for SIBs.In the study,the dopant strategy is utilized to construct nitrogen/sulfur-doped non-graphitized carbon(N-NGC or S-NGC)shell decorated on three-dimensional graphene foam(GF)as a self-support electrode.The highly disordered microstructures of heteroatom doped carbons are produced by applying a low-temperature pyrolysis treatment to precursors containing nitrogen and sulfur.The DFT calculations of Na-ion adsorption energies at diverse heteroatom sites show marginal-S,pyrrolic N and pyridinic N with more intensive Na-ion adsorption ability than middle-S,C=O and pristine carbon.The N-NGC with dominant small graphitic regions delivers adsorption ability to Na-ion,while the S-NGC with significant single carbon lattice stripes demonstrates redox reaction with Na-ion.Evidently,in comparison with only adsorption-driven slope regions at high potential for N-NGC,the redox reaction-generated potentialplateau enables non-graphitized S-NGC superior discharge/charge capacity and cycle-stability in the slope region.This work could provide deep insight into the rational design of non-graphitized carbon with rich microstructure and composition. | Peilin Zhang Chen Huang Mingzhen Xiu Siyu Zhu Weiwei Wang Bo Zhu Likang Qin Yizhong Huang Luyang Chen | 2023 | Journal of Energy Chemistry2023，，4： | 0 |
| 18 | Cux1^(+)proliferative basal cells promote epidermal hyperplasia in chronic dry skin disease identified by single-cell RNA transcriptomics显示文摘Pathological dry skin is a disturbing and intractable healthcare burden,characterized by epithelial hyperplasia and severe itch.Atopic dermatitis(AD)and psoriasis models with complications of dry skin have been studied using single-cell RNA sequencing(scRNA-seq).However,scRNA-seq analysis of the dry skin mouse model(acetone/ether/water(AEW)-treated model)is still lacking.Here,we used scRNA-seq and in situ hybridization to identify a novel proliferative basal cell(PBC)state that exclusively expresses transcription factor CUT-like homeobox 1(Cux1).Further in vitro study demonstrated that Cux1 is vital for keratinocyte proliferation by regulating a series of cyclin-dependent kinases(CDKs)and cyclins.Clinically,Cux1+PBCs were increased in patients with psoriasis,suggesting that Cux1+PBCs play an important part in epidermal hyperplasia.This study presents a systematic knowledge of the transcriptomic changes in a chronic dry skin mouse model,as well as a potential therapeutic target against dry skin-related dermatoses. | Minhua Huang Ning Hua Siyi Zhuang Qiuyuan Fang Jiangming Shang Zhen Wang Xiaohua Tao Jianguo Niu Xiangyao Li Peilin Yu Wei Yang | 2023 | Journal of Pharmaceutical Analysis2023，13，7： | 0 |
| 19 | RRCNN: Request Response-Based Convolutional Neural Network for ICS Network Traffic Anomaly Detection显示文摘Nowadays,industrial control system(ICS)has begun to integrate with the Internet.While the Internet has brought convenience to ICS,it has also brought severe security concerns.Traditional ICS network traffic anomaly detection methods rely on statistical features manually extracted using the experience of network security experts.They are not aimed at the original network data,nor can they capture the potential characteristics of network packets.Therefore,the following improvements were made in this study:(1)A dataset that can be used to evaluate anomaly detection algorithms is produced,which provides raw network data.(2)A request response-based convolutional neural network named RRCNN is proposed,which can be used for anomaly detection of ICS network traffic.Instead of using statistical features manually extracted by security experts,this method uses the byte sequences of the original network packets directly,which can extract potential features of the network packets in greater depth.It regards the request packet and response packet in a session as a Request-Response Pair(RRP).The feature of RRP is extracted using a one-dimensional convolutional neural network,and then the RRP is judged to be normal or abnormal based on the extracted feature.Experimental results demonstrate that this model is better than several other machine learning and neural network models,with F1,accuracy,precision,and recall above 99%. | Yan Du Shibin Zhang Guogen Wan Daohua Zhou Jiazhong Lu Yuanyuan Huang Xiaoman Cheng Yi Zhang Peilin He | 2023 | Computers, Materials & Continua2023，，6： | 0 |
| 20 | General approach for atomically dispersed precious metal catalysts toward hydrogen reaction显示文摘As a carbon-free energy carrier,hydrogen has become the pivot for future clean energy,while efficient hydrogen production and combustion still require precious metal-based catalysts.Single-atom catalysts(SACs)with high atomic utilization open up a desirable perspective for the scale applications of precious metals,but the general and facile preparation of various precious metal-based SACs remains challenging.Herein,a general movable printing method has been developed to synthesize various precious metal-based SACs,such as Pd,Pt,Rh,Ir,and Ru,and the features of highly dispersed single atoms with nitrogen coordination have been identified by comprehensive characterizations.More importantly,the synthesized Pt-and Ru-based SACs exhibit much higher activities than their corresponding nanoparticle counterparts for hydrogen oxidation reaction and hydrogen evolution reaction(HER).In addition,the Pd-based SAC delivers an excellent activity for photocatalytic hydrogen evolution.Especially for the superior mass activity of Ru-based SACs toward HER,density functional theory calculations confirmed that the adsorption of the hydrogen atom has a significant effect on the spin state and electronic structure of the catalysts. | Ruisong Li Daoxiong Wu Peng Rao Peilin Deng Jing Li Junming Luo Wei Huang Qi Chen Zhenye Kang Yijun Shen Xinlong Tian | 2023 | Carbon Energy2023，5，7： | 0 |
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