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| 1 | Role of the IL-33-ST2 axis in sepsis显示文摘Sepsis remains a major clinical problem with high morbidity and mortality. As new inflammatory mediators are characterized, it is important to understand their roles in sepsis. Interleukin 33(IL-33) is a recently described member of the IL-1 family that is widely expressed in cells of barrier tissues. Upon tissue damage, IL-33 is released as an alarmin and activates various types of cells of both the innate and adaptive immune system through binding to the ST2/IL-1 receptor accessory protein complex. IL-33 has apparent pleiotropic functions in many disease models, with its actions strongly shaped by the local microenvironment. Recent studies have established a role for the IL-33-ST2 axis in the initiation and perpetuation of inflammation during endotoxemia, but its roles in sepsis appear to be organism and model dependent. In this review, we focus on the recent advances in understanding the role of the IL-33/ST2 axis in sepsis. | Hui Xu Heth R. Turnquist Rosemary Hoffman Timothy R. Billiar | 2017 | Military Medical Research2017，4，1： | 14 |
| 2 | 法律术语翻译原则的符号学诠释显示文摘由于法律术语是法律概念的语言符号,法律术语翻译作为符号意义的转换与重构而兼具语言的符号性和法律的专业性。文章以符号学为理论基础,发现在法律术语制定、解释、翻译到接受整个过程中共实现了两次主动符内联系,并基于语义三角模型与翻译三角模型从符号表象、意义和符号解释角度解读了法律术语翻译五原则。此外,文章还发现语料库从微观角度研究翻译特征对法律术语翻译原则及法律翻译的探索具有指导与反哺意义。 | 程乐 Graig Hoffman | 2017 | 浙江工商大学学报2017，，6： | 6 |
| 3 | Remarkable Link between Projected Uncertainties of Arctic Sea-Ice Decline and Winter Eurasian Climate显示文摘We identify that the projected uncertainty of the pan-Arctic sea-ice concentration(SIC) is strongly coupled with the Eurasian circulation in the boreal winter(December–March; DJFM), based on a singular value decomposition(SVD) analysis of the forced response of 11 CMIP5 models. In the models showing a stronger sea-ice decline, the Polar cell becomes weaker and there is an anomalous increase in the sea level pressure(SLP) along 60°N, including the Urals–Siberia region and the Iceland low region. There is an accompanying weakening of both the midlatitude westerly winds and the Ferrell cell,where the SVD signals are also related to anomalous sea surface temperature warming in the midlatitude North Atlantic.In the Mediterranean region, the anomalous circulation response shows a decreasing SLP and increasing precipitation. The anomalous SLP responses over the Euro-Atlantic region project on to the negative North Atlantic Oscillation–like pattern.Altogether, pan-Arctic SIC decline could strongly impact the winter Eurasian climate, but we should be cautious about the causality of their linkage. | Hoffman H.N.CHEUNG Noel KEENLYSIDE Nour-Eddine OMRANI Wen ZHOU | 2018 | Advances in Atmospheric Sciences2018，35，1： | 6 |
| 4 | Quality indicators for colonoscopy显示文摘 | Douglas K. Rex John L. Petrini Todd H. Baron Amitabh Chak Jonathan Cohen Stephen E. Deal Brenda Hoffman Brian C. Jacobson Klaus Mergener Bret T. Petersen Michael A. Safdi Douglas O. Faigel Irving M. Pike | 2006 | Gastrointestinal Endoscopy2006，，4： | 4 |
| 5 | 显微CT的锥束重建技术显示文摘显微CT技术一直是Iowa大学CT/显微CT实验室研究的焦点。这篇文章报告了我们在锥束显微CT方面最近取得的一些进展。我们利用Feldkamp类算法进行了多X光源和检测器偏置条件下的近似图象重建;解释了Grangeat精确重构框架下的图象伪影。最后重点介绍了最近有关一般分块迭代Landweber格式的收敛性结果;给出了模拟和实验结果,探讨了进一步的研究方向。 | 王革 姜明 Seung Wook Lee 刘泓 Eric Hoffman | 2002 | CT理论与应用研究(中英文)2002，11，3： | 4 |
| 6 | 获得性单纯无巨核细胞性血小板减少性紫癜显示文摘本症简称APATP,是一种较少见的骨髓衰竭,其特点是严重的血小板减少伴骨髓巨核细胞数绝对缺乏或显著减少。许多疾病,包括再障、急性白血病、骨髓增生异常征及化疗效疗后,常引起巨核细胞和血小板减少,但它们大多伴有其他造血系的明显异常,而APATP其他造血细胞的改变轻微。 | Hoffman R 陆德炎 | 1993 | 国外医学(输血及血液学分册)1993，16，1： | 4 |
| 7 | En bloc resection for locally advanced cancer of the pancreas: Is it worthwhile?显示文摘 | Aaron R. Sasson M.D. John P. Hoffman M.D. Eric A. Ross Ph.D. Steven A. Kagan James F. Pingpank M.D. Burton L. Eisenberg M.D | 2002 | Journal of Gastrointestinal Surgery2002，，2： | 4 |
| 8 | 在每日的内视镜检查法常规挑选操作员 choledochoscopy 和它的角色显示文摘 Different diagnostic procedures exist for the detection of bile duct lesions in clinical practice.However,neither retrograde contrast imaging of the bile duct endoscopic retrograde cholangiopancreatogram nor other imaging procedures allow a safe diagnosis of the lesions.Therefore choledochoscopy may be a useful diagnostic procedure in macroscopic assessing lesions of the bile duct.Even if the diagnostic sensitivity and specificity is not sufficient,first studies suggest an enhanced diagnostic accuracy for choledochoscopy.Since the progress of choledochoscopy has started in the 1970 different improvements were achieved.Meanwhile,the examination can be performed by an examiner and samples can be taken.Image and Resolution quality has improved over the past years,also.The SpyGlass system is a technically advanced cholangioscopic device to provide endoscopic diagnosis in case of inconclusive bile duct findings.Further more,two more lumina allow specific biopsy forceps and optical fibers for electrohydraulic or laser lithotripsy.The most frequent useful insert of SpyGlass in clinical practice are in complex gallstones and bile duct lesions of unclear dignity. | Arthur Hoffman Johannes Wilhelm Rey Ralf Kiesslich | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，5： | 3 |
| 9 | How Do Delirium and Dementia Increase Length of Stay of Elderly General Medical Inpatients?显示文摘 | Stephen M. Saravay Michael Kaplowitz John Kurek David Zeman Simcha Pollack Sonia Novik Scott Knowlton Michael Brendel Lillian Hoffman | 2011 | Psychosomatics2011，，3： | 3 |
| 10 | Cardiovascular Function and Treatment in β-Thalassemia Major: A Consensus Statement From the American Heart Association显示文摘 | Dudley J. Pennell James E. Udelson Andrew E. Arai Biykem Bozkurt Alan R. Cohen Renzo Galanello Timothy M. Hoffman Michael S. Kiernan Stamatios Lerakis Antonio Piga John B. Porter John Malcolm Walker John Wood | 2013 | Circulation2013，，3： | 3 |
| 11 | The alternative of CubeSat-based advanced infrared and microwave sounders for high impact weather forecasting显示文摘近年来,小卫星技术的发展给传统气象卫星提供了经济有效的替补方案。本文针对可能出现的传统气象卫星的缺失情形,借助快速的区域观测系统模拟试验,探索了利用小卫星填补空缺的可能性。研究表明,单个小卫星,无论是近红外高光谱还是微波探测仪,都能够对局地强风暴天气的预报有所改进。然而,为了填补传统卫星缺失带来的影响,需要发射三颗甚至更多的小卫星来增加观测的覆盖面,以弥补小卫星精度略低、通道略少的缺陷。 | LI Zhenglong LI Jun SCHMIT Timothy J. WANG Pei LIM Agnes LI Jinlong NAGLE Fredrick W. BAI Wenguang OTKIN Jason A. ATLAS Robert HOFFMAN Ross N. BOUKABARA Sid-Ahmed ZHU Tong BLACKWELL William J. PAGANO Thomas S. | 2019 | Atmospheric and Oceanic Science Letters2019，12，2： | 3 |
| 12 | Measuring the Customer Experience in Online Environments: A Structural Modeling Approach显示文摘 | Thomas P. Novak Donna L. Hoffman Yiu-Fai Yung | 2000 | Marketing Science2000，，1： | 3 |
| 13 | Hepatitis C virus genotypes distribution and transmission risk factors in Luxembourg from 1991 to 2006显示文摘AIM:To analyze the Hepatitis C virus (HCV) genotype distribution and transmission risk factors in a population of unselected patients in Luxembourg. METHODS:Epidemiological information (gender, age and transmission risks) were collected from 802 patients newly diagnosed for hepatitis C and living in Luxembourg, among whom 228 patients referred from prison. Genotyping using 5'noncoding (5'NC) sequencing was performed. We compared categorical data using the Fisher's exact F-test and odds ratios (OR) were calculated for evaluating association of HCV genotype and risk factors. RESULTS:The sex ratio was predominantly male (2.2) and individuals aged less than 40 years represented 49.6% of the population. Genotype 1 was predominant (53.4%) followed by genotype 3 (33%). Among risk factors, intravenous drug usage (IVDU) was the most frequently reported (71.4%) followed by medical-related transmission (17.6%) including haemophilia, transfusion recipients and other nosocomial reasons. Genotype 3 was significantly associated to IVDU (OR = 4.84, P < 0.0001) whereas genotype 1 was significantly associated with a medical procedure (OR = 2.42, P < 0.001). The HCV genotype distribution from inmate patients differed significantly from the rest of the population (Chi-square test with four degrees of freedom, P < 0.0001) with a higher frequency of genotype 3 (46.5% vs 27.5%) and a lower frequency of genotype 1 and 4 (44.7% vs 56.8% and 5.3% vs 9.6%, respectively). IVDU was nearly exclusively reported as a risk factor in prison. CONCLUSION:We report the first description of the HCV genotype distribution in Luxembourg. The repartition is similar to other European countries, with one of the highest European prevalence rates of genotype 3 (33%). Since serology screening became available in 1991, IVDU remains the most common way of HCV transmission in Luxembourg. | Francois Roman Karin Hawotte Daniel Struck Anne-Marie Ternes Jean-Yves Servais Vic Arendt Patrick Hoffman Robert Hemmer Thérèse Staub Carole Seguin-Devaux Jean-Claude Schmit | 2008 | World Journal of Gastroenterology2008，14，8： | 3 |
| 14 | EVA预辐射接枝N-异丙基丙烯酰胺制备热敏性材料显示文摘采用预辐射接枝法,将N-异丙基丙烯酰胺(NIPAAm)接枝到乙烯-醋酸乙烯酯共聚物(EVA)试片上。研究了各种因素对接枝反应的影响。结果表明,接枝体系具有一般预辐照液-固两相接枝体系的共性,如在接枝反应前期,反应速度不变,以后逐渐下降,接枝率与反应温度成正比,少量的Cu(NO3)2,就能使接枝率急剧下降。经NIPAAm接枝的EVA表面,呈现与NIPAAm凝胶相似的热敏性,即在低于“较低临界溶解温度”(LCST)的温度时溶胀于水,而在高于LCST时,迅速退溶胀,其LCST约为32℃,水含量随温度的变化是可逆的。相比之下,接枝NIPAAm的EVA表面比NIPAAm凝胶具有更灵敏的热敏性。试片的LCST会随着接枝层的组成变化而漂移。 | 丁中立 浦鸿汀 叶宏 马瑞德 Allan.S Hoffman | 1994 | 辐射研究与辐射工艺学报1994，12，1： | 3 |
| 15 | microRNAs and Alu elements in the p53-Mdm2-Mdm4 regulatory network显示文摘 | Yonit Hoffman Yitzhak Pilpel Moshe Oren | 2014 | Journal of Molecular Cell Biology2014，8，3： | 2 |
| 16 | A simple and very efficient method for generating cDNA libraries 显示文摘 | Gubler U Hoffman BJ | 1983 | Gene1983，25，23： | 2 |
| 17 | Impact of freezing and thawing on the quality of meat: Review显示文摘 | Coleen Leygonie Trevor J. Britz Louwrens C. Hoffman | 2012 | Meat Science2012，，2： | 2 |
| 18 | Ethylene Biosynthesis and its Regulation in Higher Plants显示文摘 | S F Yang N E Hoffman | 1984 | Annual Review of Plant Physiology1984，，： | 2 |
| 19 | The incidence of congenital heart disease显示文摘 | Julien I.E Hoffman Samuel Kaplan | 2002 | Journal of the American College of Cardiology2002，，12： | 2 |
| 20 | Skin toxicity determined in vitro by three- dimensional,native-state histoculture显示文摘 | Li L N Margolis L B Hoffman R M | 1991 | Proc Natl Acad Sci USA1991，88，： | 2 |
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