|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | GRADE指南:Ⅶ.证据质量评价--不一致性显示文摘本文针对二分类变量结局指标相对(而非绝对)治疗效果的不一致性。证据本身不会因不同研究结果具有一致性而升级,但可能因不一致而降低质量级别。衡量一致性的标准包括点估计值的相似性、可信区间的重叠程度以及统计学判定标准包括异质性检验和I2。系统评价作者应提出并检验少数几个与患者、干预措施、结局指标以及方法学相关的先验假设以探寻异质性来源。当不一致性很大且无法解释时,因不一致性而降低质量级别是恰当的,特别当某些研究显示有显著益处而其他显示无益甚至有害时(而非仅是疗效大与疗效小的比较)。明显的亚组效应可能不可靠。如果亚组效应满足以下条件,其可信度将会增加:基于少数几个有具体方向的先验假设、亚组比较来自研究内而非研究间、交互检验的P值小、结果有生物学意义。 | Gordon H.Guyatt Andrew D.Oxman Regina Kunz James Woodcock Jan Brozek Mark Helfand Pablo Alonso-Coello Paul Glasziou Roman Jaeschke Elie A.Akl Susan Norris Gunn Vist Philipp Dahm Vijay K.Shukla Julian Higgins Yngve Falck-Ytter Holger J.Schünemann 代表GRADE小组 李幼平 杨晓妍 王莉 蔡羽嘉 陈群飞 | 2011 | 中国循证医学杂志2011，11，12： | 33 |
| 2 | 数字技术支持的教师学习:研究与项目综述(上)显示文摘本文在系统回顾教师知识与教师学习本质的基础上,讨论了数字技术与教师学习活动之间的关系,主张将数字技术的效用描述为教师学习中有目的的一组活动,即:知识建构、分布式认知、社群与沟通以及约定,通过对五个技术支持的教师学习的典型案例,分析了数字技术对教师学习的支持作用。最后指出了数字技术支持的教师学习与专业发展之方向。 | Tony Fisher Chris Higgins Avril Loveless 焦建利(译) | 2008 | 远程教育杂志2008，26，4： | 9 |
| 3 | From the Early Paleozoic Platforms of Baltica and Laurentia to the Caledonide Orogen of Scandinavia and Greenland显示文摘 | David G. Gee Haakon Fossen Niels Henriksen Anthony K. Higgins | 2008 | Episodes2008，31，1： | 5 |
| 4 | The DNA Topoisomerase VI-B Subunit OsMTOPVIB Is Essential for Meiotic Recombination Initiation in Rice显示文摘 | Ming Fu ChongWang Feiyang Xue James Higgins Mingjiao Chen Dabing Zhang Wanqi Liang | 2016 | Molecular Plant2016，9，11： | 4 |
| 5 | 数字技术支持的教师学习:研究与项目综述(下)显示文摘本文在系统回顾教师知识与教师学习本质的基础上,讨论了数字技术与教师学习活动之间的关系,主张将数字技术的效用描述为教师学习中有目的的一组活动,即:知识建构、分布式认知、社群与沟通以及约定,通过对五个技术支持的教师学习的典型案例,分析了数字技术对教师学习的支持作用。最后指出了数字技术支持的教师学习与专业发展之方向。 | Tony Fisher Chris Higgins Avril Loveless 焦建利 | 2008 | 远程教育杂志2008，26，5： | 4 |
| 6 | Mesoporous Ag nanocubes synthesized via selectively oxidative etching at room temperature for surface- enhanced Raman spectroscopy显示文摘Silver nanocubes enriched with {100} facets have been extensively used for surface-enhanced Raman scattering. Herein, we report a new water-phase synthesis method for weU-defined Ag nanocubes with tunable sizes via a two-step procedure at room temperature. First, irregularly shaped Ag nanoparticles (INPs) were prepared by reducing silver ammonia solution using ethylal. Second, the agglomerated INPs were selectively etched with HNO3 and C1- to yield {100} facet-rich mesoporous Ag nanocubes. The mechanism of Ag-nanocube formation and growth was investigated in detail by elucidating the involved chemical reactions and physical changes at each step during the synthesis. The addition of C1- anions was responsible for facilitating Ag nanoparticle growth by removing surface-adsorbed Ag+ species, thereby eliminating inter-particle repulsive forces. This agglomeration was found crucial for the subsequent selective oxidation of Ag nanoparticles because the protective agent used, polyvinylpyrrolidone (PVP), was the most effective one for adsorption on the surfaces of Ag nanoparticles of size greater than approximately 50 nm. Importantly mesopores were found inside the Ag nanocubes; this can be attributed to the unavoidable imperfect packing during the agglomeration of INPs. The newly prepared Ag nanocubes were further used to enhance the Raman signal of rhodamine 6G, which is capable of reducing the detection limitation to 10-16 mol·L-1. | Lin Gan Meijia Yang Xi Ke Guofeng Cui Xudong Chen Shiva Gupta William Kellogg Drew Higgins Gang Wu | 2015 | Nano Research2015，8，7： | 4 |
| 7 | 纳入研究的质量评价:数据提取形式的新建议显示文摘纳人研究的方法学质量评价是Cochrane系统评价不可或缺的组成部分之一。目前,《Cochrane干预措施系统评价手册》对分配隐藏的评价提出了具体的指导意见(分为“充分”、“不充分”或“不清楚”),且这些评价结果可直接进人RevMan。但对于其它方面的质量,如盲法和意向治疗分析的使用,却是由不同的系统评价小组以不同的方式在阐述。 | Julian Higgins Doug Altman 刁骧 秦莉 | 2007 | 中国循证医学杂志2007，7，1： | 4 |
| 8 | Subseasonal features of the Asian summer monsoon in the NCEP climate forecast system显示文摘The operational climate forecast system(CFS)of the US National Centers for Environmental Prediction provides climate predictions over the world,and CFS products are becoming an important source of information for regional climate predictions in many Asian countries where monsoon climate dominates.Recent studies have shown that,on monthly-to-seasonal time-scales,the CFS is highly skillful in simulating and predicting the variability of the Asian monsoon.The higher-frequency variability of the Asian summer monsoon in the CFS is analyzed,using output from a version with a spectral triangular truncation of 126 waves in horizontal and 64 sigma layers in vertical,focusing on synoptic,quasi-biweekly,and intraseasonal time-scales.The onset processes of different regional monsoon components were investigated within Asia.Although the CFS generally overestimates variability of monsoon on these time-scales,it successfully captures many major features of the variance patterns,especially for the synoptic time-scale.The CFS also captures the timing of summer monsoon onsets over India and the Indo-China Peninsula.However,it encounters difficulties in simulating the onset of the South China Sea monsoon.The success and failure of the CFS in simulating the onset of monsoon precipitation can also be seen from the associated features of simulated atmospheric circulation processes.Overall,the CFS is capable of simulating the synoptic-to-intraseasonal variability of the Asian summer monsoon with skills.As for seasonal-to-interannual time-scales shown previously,the model is expected to possess a potential for skillful predictions of the high-frequency variability of the Asian monsoon. | Song YANG WEN Min R Wayne HIGGINS | 2008 | Acta Oceanologica Sinica2008，27，3： | 3 |
| 9 | 流域生态修复系统规划方法及其应用--以美国佩诺布斯科特河为例显示文摘河流生态修复对于改善退化的河流生态系统具有重要作用。以美国缅因州佩诺布斯科特河的生态修复项目为例,介绍了一种流域生态修复系统规划方法,具体说明了方法的应用过程。该方法以流域为评估单位,以数据和多种分析方法为支撑;强调在规划之初开展以数据为基础的现状分析,并与利益相关方共同规划修复目标以保证项目长期可持续开展;根据威胁识别保护策略,定量地分析保护情景;最终选择可行的高生态效益保护方案。同时倡导在推动流域修复的同时实施监测与适应性管理,为保护项目的长效机制提供有效反馈。通过对比分析国内外河流生态修复在目标、理念、具体方法及项目监测调整上的差异,为今后国内的河流生态修复研究与实践提供参考。 | 刘昊 靳彤 李丹宁 汪卢弘 王龙柱 郭乔羽 Jonathan Higgins Nicholas Miller Joshua Royte | 2018 | 环境影响评价2018，40，4： | 3 |
| 10 | Impacts of Land Process on the Onset and Evolution of Asian Summer Monsoon in the NCEP Climate Forecast System显示文摘Impacts of land models and initial land conditions(ICs) on the Asian summer monsoon,especially its onset,were investigated using the NCEP Climate Forecast System(CFS).Two land models,the Oregon State University(OSU) land model and the NCEP,OSU,Air Force,and Hydrologic Research Laboratory(Noah) land model,were used to get parallel experiments.The experiments also used land ICs from the NCEP/Department of Energy(DOE) Global Reanalysis 2(GR2) and the Global Land Data Assimilation System(GLDAS).Previous studies have demonstrated that,a systematic weak bias appears in the modeled monsoon,and this bias may be related to a cold bias over the Asian land mass.Results of the current study show that replacement of the OSU land model by the Noah land model improved the model's cold bias and produced improved monsoon precipitation and circulation patterns.The CFS predicted monsoon with greater proficiency in El Nin o years,compared to La Nin a years,and the Noah model performed better than the OSU model in monsoon predictions for individual years.These improvements occurred not only in relation to monsoon onset in late spring but also to monsoon intensity in summer.Our analysis of the monsoon features over the India peninsula,the Indo-China peninsula,and the South Chinese Sea indicates different degrees of improvement.Furthermore,a change in the land models led to more remarkable improvement in monsoon prediction than did a change from the GR2 land ICs to the GLDAS land ICs. | Song YANG 温敏 Rongqian YANG Wayne HIGGINS 张人禾 | 2011 | Advances in Atmospheric Sciences2011，28，6： | 3 |
| 11 | Recombinant protein expression in Pichia pastoris显示文摘 | James M. Cregg Joan Lin Cereghino Jianying Shi David R. Higgins | 2000 | Molecular Biotechnology2000，，1： | 3 |
| 12 | Recombinant protein expression in Pichia pastoris显示文摘 | James M. Cregg Joan Lin Cereghino Jianying Shi David R. Higgins | 2000 | Molecular Biotechnology2000，，1： | 3 |
| 13 | 昆士兰急救部介绍(英文)显示文摘昆士兰急救部 (QAS)是从 1892年时的一个单纯的病人运输机构 ,发展成为世界上第四大急救中心 ,拥有世界一流的院前急救的专业技术人员。QAS和昆士兰科技大学 (QUT)合作培养急救的专业人员和管理专家。因为QAS的急救服务不是一个“使用者支付”的系统 ,所以它能保证急救服务于每个人。QAS作为一个政府机构 ,在它的系统组成 ,功能分布 ,人力资源分配以及发展过程方面 。 | JIM Higgins 侯香玉 | 2005 | 中华急诊医学杂志2005，14，1： | 3 |
| 14 | 冠心病中7个凝血基因的多态性:对66155例冠心病患者及91307例对照者的荟萃分析显示文摘Background: Variants of certain haemostatic genes(such as that encoding factor V Leiden) are involved in the development of venous thrombosis, but studies of such variants in coronary disease have reported apparently conflicting results. We did meta-analyses on seven such haemostatic genetic variants for which the available evidence on each comprises at least 5000 coronary disease cases and at least 5000 controls. Methods: Meta-analyses were done of 191 studies in relation to factor V G1691A(ie, factor V Leiden), factor VII G10976A, prothrombin G20210A, plasminogen activator inhibitor-1(PAI-1) [-675] 4G/5G, and three platelet glycoprotein(GP)receptor variants(GPIa C807T, GPIbα T[-5]C,GPIIIa C1565T), involving a total of 66 155 coronary disease cases and 91 307 controls. We explored potential sources of heterogeneity. Findings: In a combined analysis of all studies, the per-allele relative risks(RR) for coronary disease of factor V 1691A and of prothrombin 20210A were 1.17(95% CI 1.08-1.28) and 1.31(1.12-1.52), respectively. Combined analyses of studies of the PAI-1 [-675] 4G variant yielded a per-allele relative risk for coronary disease of 1.06(1.02-1.10), but there was an indication of publication bias in these studies. Combined analyses of the factor VII 10976A, GPIa 807T, GPIbα [-5]C, and GPIIIa 1565T variants showed no significant overall associations with coronary disease, yielding per-allele RRs of 0.97(0.91-1.04), 1.02(0.97-1.08), 1.05(0.96-1.13), and 1.03(0.98-1.07) , respectively. Interpretation: The 1691A variant of the factor V gene and the 20210A variant of the prothrombin gene, both of which increase circulating thrombin generation, might each be moderately associated with the risk of coronary disease. Further studies are merited to assess these associations in greater detail(including any gene-gene and gene-environment interactions) and to determine any implications with regard to potential therapies designed to reverse patients prothrombotic phenotype, such as selective plasma factor V or factor Xa inhibition. | Higgins J.P. J. Danesh 马超 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，8： | 2 |
| 15 | Hepatitis B virus subgenotyping: History, effects of recombination, misclassifications, and corrections显示文摘 | Weifeng Shi Zhong Zhang Cheng Ling Weimin Zheng Chaodong Zhu Michael J. Carr Desmond G. Higgins | 2013 | Infection Genetics and Evolution2013，，： | 2 |
| 16 | Biomechanical Analysis of Distal Femur Fracture Fixation: Fixed-Angle Screw-Plate Construct Versus Condylar Blade Plate显示文摘 | Thomas F Higgins Gavin Pittman Jerod Hines Kent N Bachus | 2007 | Journal of Orthopaedic Trauma2007，，1： | 2 |
| 17 | Energy Beverages: Content and Safety显示文摘 | John P. Higgins Troy D. Tuttle Christopher L. Higgins | 2010 | Mayo Clinic Proceedings2010，，11： | 2 |
| 18 | Promotion and Prevention: Regulatory Focus as A Motivational Principle显示文摘 | E. Tory Higgins | 1998 | Advances in Experimental Social Psychology1998，，： | 2 |
| 19 | Promotion and Prevention: Regulatory Focus as A Motivational Principle显示文摘 | E. Tory Higgins | 1998 | Advances in Experimental Social Psychology1998，，： | 2 |
| 20 | Postprandial dyslipidemia in insulin resistant states in adolescent populations显示文摘Obesity and the metabolic syndrome are becoming increasingly prevalent not only in adults,but also in adolescents.The metabolic syndrome,a complex cluster of metabolic abnormalities,increases one’s risk of developing type 2 diabetes and cardiovascular disease(CVD).Dyslipidemia,a key component of the metabolic syndrome,is highly associated with insulin resistance and contributes to increased CVD risk.Dyslipidemia has traditionally been assessed using a fasting lipid profile [i.e.fasting triglycerides,total cholesterol,low-density lipoprotein cholesterol(LDL-C),and high-density lipoprotein cholesterol(HDL-C)].However,the postprandial state predominates over the course of a day and non-fasting triglycerides independently predict CVD risk.In insulin resistant states,the intestine overproduces triglyceride-rich lipoprotein(TRL) particles,termed chylomicrons(CMs),following ingestion of a fat-containing meal,as well as in the fasting state.Along with elevated hepatic TRLs(i.e.very-low density lipoproteins),CMs contribute to remnant lipoprotein accumulation,small dense LDL particles,and reduced HDL-C,which collectively increase CVD risk.Given the early genesis of atherosclerosis and physiological metabolic changes during adolescence,studying postprandial dyslipidemia in the adolescent population is an important area of study.Postprandial dyslipidemia in the pediatric population poses a significant public health concern,warranting a better understanding of its pathogenesis and association with insulin resistance and CVD.This review discusses the metabolic syndrome,focusing on the link between insulin resistance,postprandial dyslipidemia,and CVD risk.Furthermore,the clinical significance and functional assessment of postprandial dyslipidemia,specifically in the adolescent population,is discussed in more detail. | Victoria Higgins Khosrow Adeli | 2020 | The Journal of Biomedical Research2020，34，5： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员