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| 1 | Reprogramming of ovine adult fibroblasts to pluripotency via drug-inducible expression of defined factors显示文摘在 enucleated 鸡蛋的体的房间的 Reprogramming 做了多丽,绵羊,在 1996 的第一个成功地克隆的哺乳动物。然而,绵羊的机制体的房间 reprogramming 还没被探讨了。而且,绵羊胚胎的茎(ES ) 细胞仍然不是可得到的,它限制精确修改基因的绵羊的产生。在这研究,我们报导体的房间能是的那只绵羊直接 reprogrammed 到导致的 pluripotent 用定义因素(Oct4, Sox2, c-Myc, Klf4, Nanog, Lin28, SV40 大 T 和 hTERT ) 的茎(iPS ) 房间。我们的观察显示从绵羊的体的细胞比从另外的种,在 iPS,细胞被报导了的体的细胞对改编更困难。我们证明绵羊 iPS 房间表示 ES 房间标记,包括碱的磷酸酶, Oct4, Nanog, Sox2, Rex1,阶段特定的胚胎的 antigen-1, TRA-1-60, TRA-1-81 和 E-cadherin。绵羊 iPS 房间展出了正常 karyotypes 并且能在 vitro 并且在 teratomas 区分进所有三细菌层。我们的学习可以帮助在绵羊揭示体的房间 reprogramming 的机制并且提供一个平台为绵羊 ES 房间探索文化条件。而且,绵羊 iPS 房间可以直接被用来产生精确修改基因的绵羊。 | Lei Bao Lixiazi He Jijun Chen Zhao Wu Jing Liao Lmgdun Rao Jiangtao Ren Hui Li Hui Zhu Lei Qian Yijun Gu Huimin Dai Xun Xu Jinqiu Zhou Wen Wang Chun Cui Lei Xiao | 2011 | Cell Research2011，21，4： | 32 |
| 2 | Isoliquiritigenin inhibits TGF-β1-induced fibrogenesis through activating autophagy via PI3K/AKT/mTOR pathway in MRC-5 cells显示文摘Isoliquiritigenin(ISL),a natural flavonoid derived from the root of liquorice,has been reported to possess anti-inflammatory and antioxidant activities.Previous studies have found that ISL plays a crucial role in anti-fibrosis of adipose tissue and renal tissue;however,its effect on pulmonary fibrogenesis has not been demonstrated.In this study,we aimed to explore the roles and the underlying mechanisms of ISL in TGF-β1-induced fibrogenesis using human lung fibroblast-derived MRC-5 cells.Cell proliferation and migration were determined by MTT and wound healing assay,respectively.The expression levels of alpha-smooth muscle actin(α-SMA),collagen type I alpha 1(COLIA1)and fibronectin(FN),microtubule-associated protein light chain 3(LC3)and related signaling molecules were detected by quantitative real-time PCR,western blot and immunofluorescence assay,correspondingly.EGFP-LC3 transfection was used for autophagy analysis.The results showed that ISL inhibited the TGF-β1-induced proliferation and migration,and down-regulated the expressions ofα-SMA,COLIA1 and FN.ISL treatment led to up-regulation of LC3 in TGF-β1-treated MRC-5 cells,accompanied by significant decrease in the phosphorylation levels of phosphatidylinositol 3-kinase(PI3K),protein kinase B(AKT),and mammalian target of rapamycin(mTOR).In addition,the inhibitory effects of ISL on TGF-β1-induced fibrogenic features in MRC-5 cells were enhanced by pretreatment with autophagy activator Rapmycin and PI3K/AKT inhibitor LY294002 and reversed by autophagy inhibitor 3-methyladenine and PI3K/AKT activator IGF-1.Taken together,our results demonstrated that ISL could attenuate the fibrogenesis of TGF-β1-treated MRC-5 cells by activating autophagy via suppressing the PI3K/AKT/mTOR pathway.Therefore,ISL holds a great potential to be developed as a novel therapeutic agent for the treatment of pulmonary fibrosis. | Jinjuan He Hao Peng Meifang Wang Ying Liu Xingrong Guo Bin Wang Longjun Dai Xueqin Cheng Zhongji Meng Leyong Yuan Fenglin Cai Yijun Tang | 2020 | Acta Biochimica et Biophysica Sinica2020，52，8： | 16 |
| 3 | ZnO@MOF@PANI core-shell nanoarrays on carbon cloth for high-performance supercapacitor electrodes显示文摘Hierarchical ZnO@metal-organic framework @polyaniline(ZnO@MOF@PANI) core-shell nanorod arrays on carbon cloth has been fabricated by combining electrodeposition and hydrothermal method. Well-ordered Zn O nanorods not only act as a scaffold for growth of MOF/PANI shell but also as Zn source for the formation of MOF. The morphology of ZnO@MOF@PANI composite is greatly influenced by the number of PANI electrodeposition cycles. Their structural and electrochemical properties were characterized with different techniques. The results indicate that the Zn O@MOF@PANI with 13 CV cycles of PANI deposition demonstrates the maximum specific capacitance of 340.7 F g-1 at 1.0 A g-1, good rate capability with84.3% capacitance retention from 1.0 to 10 A g-1 and excellent cycling life of 82.5% capacitance retention after 5000 cycles at high current density of 2.0 A g-1. This optimized core-shell nanoarchitecture endows the composite electrode with short ion diffusion pathway, rapid ion/electron transfer and high utilization of active materials, which thus result in excellent electrochemical performance of the ternary composite. | Chunmei Zhu Ying He Yijun Liu Natalia Kazantseva Petr Saha Qilin Cheng | 2019 | Journal of Energy Chemistry2019，28，8： | 10 |
| 4 | A Global Identification and Analysis of Small Nucleolar RNAs and Possible Intermediate-Sized Non-Coding RNAs in Oryza sativa显示文摘积累的证据建议非编码的 RNA (ncRNAs ) 在许多真核细胞的有机体普遍、机能上地重要。在这研究,我们采用了分别和 cDNA 图书馆构造方法列在后面由的一种特殊尺寸 454 系统地介绍米饭的深定序中间尺寸的 ncRNAs。我们的分析总共导致了 1349 ncRNAs 的鉴定,包括一个未知功能的范畴的 754 新奇 ncRNAs。所有识别 ncRNAs 的染色体分发没显示出海滨偏爱,并且显示了类似于与很少染色体相关性在编码蛋白质的基因观察了那的一个模式。非常, ncRNAs 的一半被集中在附近编码区域的 5 和 3 个终点正海滨。新奇 ncRNAs 的多数是米饭特定,当 78% 小核仁的 RNA (snoRNAs ) 被保存时。双人脚踏车复制驾驶了扩大在 snoRNA 基因家庭的一半上。而且, 90% snoRNA 候选人被显示特别地生产在 2030 nt,其 80% 通常与淘金者蛋白质被联系,和 AGO1b 之间的小 RNA。总的来说,我们的调查结果在 monocot 种提供中间尺寸的非编码的 transcriptome 的一个全面看法,它将为 ncRNA 函数的深入的分析用作一个有用平台。 | Ting-Ting Liu Danmeng Zhu Wei Chen Wei Deng Hang He Guangming He Baoyan Bai Yijun Qi Runsheng Chen Xing Wang Deng | 2013 | Molecular Plant2013，6，3： | 10 |
| 5 | Generation of hircine-induced pluripotent stem cells by somatic cell reprogramming显示文摘 | Jiangtao Ren Yongjun Pak Lixiazi He Lei Qian Yijun Gu Hui Li Lingjun Rao Jing Liao Chun Cui Xun Xu Jinqiu Zhou Hakchol Ri Lei Xiao | 2011 | Cell Research2011，21，5： | 10 |
| 6 | Development and validation of an endoscopic images-based deep learning model for detection with nasopharyngeal malignancies显示文摘Background:Due to the occult anatomic location of the nasopharynx and frequent presence of adenoid hyperpla-sia,the positive rate for malignancy identification during biopsy is low,thus leading to delayed or missed diagnosis for nasopharyngeal malignancies upon initial attempt.Here,we aimed to develop an artificial intelligence tool to detect nasopharyngeal malignancies under endoscopic examination based on deep learning.Methods:An endoscopic images-based nasopharyngeal malignancy detection model(eNPM-DM)consisting of a fully convolutional network based on the inception architecture was developed and fine-tuned using separate training and validation sets for both classification and segmentation.Briefly,a total of 28,966 qualified images were collected.Among these images,27,536 biopsy-proven images from 7951 individuals obtained from January 1st,2008,to December 31st,2016,were split into the training,validation and test sets at a ratio of 7:1:2 using simple randomiza-tion.Additionally,1430 images obtained from January 1st,2017,to March 31st,2017,were used as a prospective test set to compare the performance of the established model against oncologist evaluation.The dice similarity coef-ficient(DSC)was used to evaluate the efficiency of eNPM-DM in automatic segmentation of malignant area from the background of nasopharyngeal endoscopic images,by comparing automatic segmentation with manual segmenta-tion performed by the experts.Results:All images were histopathologically confirmed,and included 5713(19.7%)normal control,19,107(66.0%)nasopharyngeal carcinoma(NPC),335(1.2%)NPC and 3811(13.2%)benign diseases.The eNPM-DM attained an overall accuracy of 88.7%(95%confidence interval(CI)87.8%-89.5%)in detecting malignancies in the test set.In the prospective comparison phase,eNPM-DM outperformed the experts:the overall accuracy was 88.0%(95%CI 86.1%-89.6%)vs.80.5%(95%CI 77.0%-84.0%).The eNPM-DM required less time(40 s vs.110.0±5.8 min)and exhibited encouraging performance in automatic segmentation of nasopharyngeal malignant area from the background,with an average DSC of 0.78±0.24 and 0.75±0.26 in the test and prospective test sets,respectively.Conclusions:The eNPM-DM outperformed oncologist evaluation in diagnostic classification of nasopharyngeal mass into benign versus malignant,and realized automatic segmentation of malignant area from the background of nasopharyngeal endoscopic images. | Chaofeng Li Bingzhong Jing Liangru Ke Bin Li Weixiong Xia Caisheng He Chaonan Qian Chong Zhao Haiqiang Mai Mingyuan Chen Kajia Cao Haoyuan Mo Ling Guo Qiuyan Chen Linquan Tang Wenze Qiu Yahui Yu Hu Liang Xinjun Huang Guoying Liu Wangzhong Li Lin Wang Rui Sun Xiong Zou Shanshan Guo Peiyu Huang Donghua Luo Fang Qiu Yishan Wu Yijun Hua Kuiyuan Liu Shuhui Lv Jingjing Miao Yanqun Xiang Ying Sun Xiang Guo Xing Lv | 2018 | Cancer Communications2018，38，1： | 9 |
| 7 | Conformal isoparametric hypersurfaces with two distinct conformal principal curvatures in conformal space显示文摘The conformal geometry of regular hypersurfaces in the conformal space is studied.We classify all the conformal isoparametric hypersurfaces with two distinct conformal principal curvatures in the conformal space up to conformal equivalence. | NIE ChangXiong 1,2,LI TongZhu 3,HE YiJun 4 & WU ChuanXi 5 1 Faculty of Mathematics and Computer Sciences,Hubei University,Wuhan 430062,China 2 School of Mathematical Sciences,Peking University,Beijing 100871,China 3 Faculty of Sciences,Beijing Institute of Technology,Beijing 100081,China 4 School of Mathematical Sciences,Shanxi University,Taiyuan 030006,China 5 Institute of Mathematics,Hubei University,Wuhan 430062,China | 2010 | Science China Mathematics2010，53，4： | 9 |
| 8 | Nanolubricant additives: A review显示文摘Using nanoadditives in lubricants is one of the most effective ways to control friction and wear,which is of great significance for energy conservation,emission reduction,and environmental protection.With the scientific and technological development,great advances have been made in nanolubricant additives in the scientific research and industrial applications.This review summarizes the categories of nanolubricant additives and illustrates the tribological properties of these additives.Based on the component elements of nanomaterials,nanolubricant additives can be divided into three types:nanometal-based,nanocarbon-based,and nanocomposite-based additives.The dispersion stabilities of additives in lubricants are also discussed in the review systematically.Various affecting factors and effective dispersion methods have been investigated in detail.Moreover,the review summarizes the lubrication mechanisms of nanolubricant additives including tribofilm formation,micro-bearing effect,self-repair performance,and synergistic effect.In addition,the challenges and prospects of nanolubricant additives are proposed,which guides the design and synthesis of novel additives with significant lubrication and antiwear properties in the future. | Jun ZHAO Yiyao HUANG Yongyong HE Yijun SHI | 2021 | Friction2021，9，5： | 9 |
| 9 | Defect and Doping Co‑Engineered Non‑Metal Nanocarbon ORR Electrocatalyst显示文摘Exploring low-cost and earth-abundant oxygen reduction reaction(ORR)electrocatalyst is essential for fuel cells and metal–air batteries.Among them,non-metal nanocarbon with multiple advantages of low cost,abundance,high conductivity,good durability,and competitive activity has attracted intense interest in recent years.The enhanced ORR activities of the nanocarbons are normally thought to originate from heteroatom(e.g.,N,B,P,or S)doping or various induced defects.However,in practice,carbon-based materials usually contain both dopants and defects.In this regard,in terms of the co-engineering of heteroatom doping and defect inducing,we present an overview of recent advances in developing non-metal carbon-based electrocatalysts for the ORR.The characteristics,ORR performance,and the related mechanism of these functionalized nanocarbons by heteroatom doping,defect inducing,and in particular their synergistic promotion effect are emphatically analyzed and discussed.Finally,the current issues and perspectives in developing carbon-based electrocatalysts from both of heteroatom doping and defect engineering are proposed.This review will be beneficial for the rational design and manufacturing of highly efficient carbon-based materials for electrocatalysis. | Jian Zhang Jingjing Zhang Feng He Yijun Chen Jiawei Zhu Deli Wang Shichun Mu Hui Ying Yang | 2021 | Nano-Micro Letters2021，13，4： | 8 |
| 10 | Ocean surface wave measurements from fully polarimetric SAR imagery显示文摘A new method for the retrieval of ocean wave parameters from SAR imagery is developed,based on the shape-from-shading(SFS)technique.Previously,the SFS technique has been used in the reconstruction of 3D landform information from SAR images,in order to generate elevation maps of topography for land surfaces.Here,in order to retrieve ocean wave characteristics,we apply the SFS methodology,together with a method to orient the angular measurements of the azimuth slope and range slope,in the measurement of ocean surface waves.This method is applied to high resolution fine-quad polarization mode(HH,VV,VH and HV)C-band RADARSAT-2 SAR imagery,in order to retrieve ocean wave spectra and extract wave parameters.Collocated in situ buoy measurements are used to validate the reliability of this method.Results show that the method can reliably estimate wave height,dominant wave period,dominant wave length and dominant wave direction from C-band SAR images.The advantage of this method is that it does not depend on modulation transfer functions(MTFs),in order to measure ocean surface waves.This method can be used in monitoring ocean surface wave propagation through open water areas into ice-covered areas,especially the marginal ice zone(MIZ)in polar oceans. | XIE Tao William PERRIE HE YiJun LI HaiYan FANG He ZHAO ShangZhuo YU WenJin | 2015 | Science China Earth Sciences2015，58，10： | 6 |
| 11 | Detection of weak ship signals with the optimization of polarimetric contrast enhancement显示文摘An optimization of polarimetric contrast enhancement method is proposed to detect ships with lowship-to-clutter power ratio.The received power is calculated with Kennaugh matrix and an iterative algo-rithm is adopted to get the optimal polarimetric states.The optimization method depresses the power of o-cean clutter and increases the power of ship signal.With the double effects,the contrast of ship to oceanis dramatically increased.Thus small ship or weak signals of low ship-to-ocean power ratio can easily bedetected.Ship signals can be distinguished from speckle noise using the different variation trend after op-timization,and thus the threshold problem can be avoided.Moreover,the analyses of different ship'sKennaugh matrices give two implications.One is that the results are affected little by choosing differentKennaugh matrices of ships with strong intensity from Synthetic Aperture Radar(SAR)images.The otheris that ship's Kennaugh matrix chosen from real SAR images is more favorable than that of ideal scatter-ing.Finally,the optimization results are confirmed by polarimetric scattering angle and co-polarizationphase difference. | 李海艳 He Yijun | 2008 | High Technology Letters2008，14，1： | 6 |
| 12 | Proteomic analysis of long-term salinity stress-responsive proteins in Thellungiella halophila leaves显示文摘Salinity is one of the most severe environmental factors that may impair crop productivity. A proteomic study based on two-dimensional gel electrophoresis is performed in order to analyze the long-term salinity stress response of Thellungiella halophila, an Arabidopsis-related halophyte. Four-week-old seedlings are exposed to long-term salinity treatment. The total crude proteins are extracted from leaf blades, separated by 2-DE, stained with Coomassie Brilliant Blue, and differentially displayed spots are identified by MALDI-TOF MS or QTOF MS/MS. Among 900 protein spots reproducibly detected on each gel, 30 spots exhibit significant change and some of them are identified. The identified proteins include not only some previously characterized stress-responsive proteins such as TIR-NBS-LRR class disease resistance protein, ferritin-1, and pathogenesis-related protein 5, but also some proteins related to energy pathway, metabolism, RNA processing and protein degradation, as well as proteins with unknown functions. The possible functions of these proteins in salinity tolerance of T. halophila are discussed and it is suggested that the long-term salinity tolerance of T. halophila is achieved, at least partly, by enhancing defense system, adjusting energy and metabolic pathway and maintaining RNA structure. | GAO Fei ZHOU YiJun HUANG LingYun HE DaChengt ZHANG GenFa | 2008 | Chinese Science Bulletin2008，53，22： | 6 |
| 13 | A new method to retrieve salinity profiles from sea surface salinity observed by SMOS satellite显示文摘This paper proposes a new method to retrieve salinity profiles from the sea surface salinity(SSS) observed by the Soil Moisture and Ocean Salinity(SMOS) satellite. The main vertical patterns of the salinity profiles are firstly extracted from the salinity profiles measured by Argo using the empirical orthogonal function. To determine the time coefficients for each vertical pattern, two statistical models are developed. In the linear model, a transfer function is proposed to relate the SSS observed by SMOS(SMOS_SSS) with that measured by Argo, and then a linear relationship between the SMOS_SSS and the time coefficient is established. In the nonlinear model, the neural network is utilized to estimate the time coefficients from SMOS_SSS, months and positions of the salinity profiles. The two models are validated by comparing the salinity profiles retrieved from SMOS with those measured by Argo and the climatological salinities. The root-mean-square error(RMSE) of the linear and nonlinear model are 0.08–0.16 and 0.08–0.14 for the upper 400 m, which are 0.01–0.07 and 0.01–0.09 smaller than the RMSE of climatology. The error sources of the method are also discussed. | YANG Tingting CHEN Zhongbiao HE Yijun | 2015 | Acta Oceanologica Sinica2015，34，9： | 6 |
| 14 | Cloning, expression, and characterization of a novel diketoreductase from Acinetobacter baylyi显示文摘oxidoreductases 催化的羰基组的减小涉及所有生物过程并且经常是重要 biocatalyst 的一个班。在这篇文章,我们报导指定为 diketoreductase (DKR ) 能与优秀 stereoselectivity 在 diketo 酉旨把二个羰基组归结为相应 dihydroxy 酉旨的新奇的酶。DKR 被反向的基因方法从 Acinetobacter baylyi 克隆,不同类地在 Escherichia coli 表示了,并且净化了到由二色析法的步的同质。这新奇的酶展出了双余因子特性,与在 NADPH 上的 NADH 的偏爱。DKR 催化的 dihydroxy 酉旨产品仅仅是有两 diastereomeric 过量的 3R,5S 立体异构, enantiomeric 过量珍视超过 99.5% 。另外,酶的一些生物化学的性质例如最佳的 pH 和温度,也被描绘。而且,顺序分析显示这新酶对细菌的 3-hydroxyacyl 辅酶相应 -- 脱氢酶。基于唯一的催化活动和优秀 stereoselectivity,更重要地, DKR 能在珍贵 chiral 药中介的合成被利用,例如 Lipitor ? 。 | Xuri Wu Nan Liu Yunmian He Yijun Chen | 2009 | Acta Biochimica et Biophysica Sinica2009，41，2： | 3 |
| 15 | Oil spill detection on the ocean surface using hybrid polarimetric SAR imagery显示文摘Hybrid-polarimetric SAR(synthetic aperture radar) is a new SAR mode, with relatively simple architecture, low cost, and wide swath, which will be carried by several Earth-observing systems from now to the near future. Here, we show how the second Stokes parameter of hybrid-polarimetric SAR can be employed to detect oil on the ocean surface using the classic well-known Otsu threshold methodology, in relation to contributions from different polarizations and dampening effects on backscatter intensity, neglecting the specific scattering mechanisms and oil types for an oil-covered surface. The detection methodology is demonstrated to be reliable in three example cases: oil-on-water experiments conducted by the Norwegian Clean Seas Association, natural oil seeps from the Gulf of Mexico, and observations from the Deep Water Horizon oil spill disaster in 2010. | LI HaiYan PERRIE William ZHOU YuanZe HE YiJun | 2016 | Science China Earth Sciences2016，59，2： | 2 |
| 16 | Reliable sensors based on graphene textile with negative resistance variation in three dimensions显示文摘The weft-knitted reduced graphene oxide(r-GO)textile that is made up of many conductive r-GO coated fibers was successfully prepared dependent on the electrospray deposition technique.Interestingly,the r-GO textile presents negative resistance variation not only in axial direction as the pressure increases but also in transverse direction as the lateral stretch increases which makes it has the advantage to fabricate the reliable sensors based on strain-resistance effect.The transverse-strain and pressure sensors based on the r-GO textiles all show the excellent sensing characteristics such as high sensitivity,reliability,and good durability,etc.The maximum gauge factors(GF)of the transverse-sensor are 27.1 and 153.5 in the x-and/-direction,respectively.And the practical detection range can up to 40%in the x-direction and 35%in the y-direction,respectively.The r-GO textile pressure sensor also shows high sensitivity for a broad pressure range that with a GF up to 716.8 kPa-1 for less than 4.5 kPa region and still has more sensitive pressure sensing characteristics even the pressure goes up to 14 kPa.Based on those good performances of r-GO textile sensors,its potential applications in human body states monitoring have been studied. | Wenpeng Han Yijun Wu He Gong Linxin Liu Junxiang Yan Mengfei Li Yunze Long Guozhen Shen | 2021 | Nano Research2021，14，8： | 2 |
| 17 | Fabrication of iridium oxide neural electrodes at the wafer level显示文摘Electro-deposition, electrical activation, thermal oxidation, and reactive ion sputtering are the four primary methods to fabricate iridium oxide film. Among these methods, reactive ion sputtering is a commonly used method in standard micro-fabrication processes. In different sputtering conditions, the component, texture, and electrochemistry character of iridium oxide varies considerably. To fabricate the iridium oxide film compatible with the wafer-level processing of neural electrodes, the quality of iridium oxide film must be able to withstand the mechanical and chemical impact of post-processing, and simultaneously achieve good performance as a neural electrode. In this study, parameters of sputtering were researched and developed to achieve a balance between mechanical stability and good electrochemical characteristics of iridium oxide film on electrode. Iridium oxide fabricating process combined with fabrication flow of silicon electrodes, at wafer-level, is introduced to produce silicon based planar iridium oxide neural electrodes. Compared with bare gold electrodes, iridium oxide electrodes fabricated with this method exhibit particularly good electrochemical stability, low impedance of 386 kW at 1 kH z, high safe charge storage capacity of 3.2 m C/cm^2, and good impedance consistency of less than 25% fluctuation. | ZHANG He PEI WeiHua ZHAO ShanShan YANG XiaoWei LIU RuiCong LIU YuanYuan WU Xian GUO DongMei GUI Qiang GUO XuHong XING Xiao WANG YiJun CHEN HongDa | 2016 | Science China(Technological Sciences)2016，59，9： | 2 |
| 18 | Vertical development of a Prorocentrum donghaiense bloom in the coastal waters of the East China Sea: coupled biophysical numerical modeling显示文摘Algal blooms caused by Prorocentrum donghaiense occurred frequently in the East China Sea(ECS) during spring in recent years. In this study, a coupled biophysical model was used to hindcast a massive P. donghaiense bloom that occurred in 2005 and to determine the factors influencing bloom initiation and development. The model comprised the Regional Ocean Modeling System tailored for the ECS that utilized a multi-nested configuration and a population dynamics model for P. donghaiense. Comparisons between simulations and observations revealed that the biological model is capable of reproducing the characteristics of P. donghaiense growth under different irradiances and phosphorus limitation scenarios. The variation of intracellular phosphorus and the effects of P. donghaiense on ambient nutrients conditions were also reproduced. The biophysical model hindcasted the hydrodynamics and spatiotemporal distributions of the P. donghaiense bloom reasonably well.Bloom development was consistent with observations reported in earlier studies. The results demonstrate the capability of the model in capturing subsurface incubation during bloom initiation. Then model's hindcast solutions were further used to diagnose the factors controlling the vertical distribution. Phosphate appeared to be one of the factors controlling the subsurface incubation, whereas surface wind fields played an important role in determining P. donghaiense distribution. The results highlight the importance of nutrient-limitation as a mechanism in the formation of P. donghaiense subsurface layers and the dispersing of P. donghaiense blooms.This coupled biophysical model should be improved and used to investigate P. donghaiense blooms occurring in different scenarios. | SUN Ke QIU Zhongfeng HE Yijun FAN Wei WEI Zexun | 2017 | Acta Oceanologica Sinica2017，36，6： | 2 |
| 19 | Four COVID-19 Cases of New Variant B.1.351 First Emerging in South Africa in Chinese Passengers on Same Flight-Shenzhen,China,January 2021显示文摘At 04∶50 on January 1,2021,a 36-year-old Chinese project manager(Case A),a 29-year-old Chinese worker(Case B),and a 53-year-old Chinese businessman(Case C)returned from Africa(Case A and B from South Africa and Case C from Lesotho)on the same flight and tested coronavirus disease 2019(COVID-19)RNA positive by real-time polymerase chain reaction(PCR)by Baoan District People’s Hospital.Shenzhen CDC received their oral nasopharyngeal swabs packages from the hospital and retested COVID-19 RNA positive at 09∶50.Meanwhile,Case D. | Cong Cheng Lei Wang Ziquan Lyu Bo Peng Yinghui Li Dongfeng Kong Le Zuo Xiaomin Zhang Chao Yang Weiwen Liu Jia Wan Yijun Tang Junjia He Ying Wen Shule Xu Weihua Wu Ying Chen Guangnan Liu Junjie Xia Xuan Zou Renli Zhang Qinghua Hu Shujiang Mei Tiejian Feng | 2021 | China CDC weekly2021，3，8： | 2 |
| 20 | Purification, composition analysis and antioxidant activity of the polysaccharides from Dendrobium nobile Lindl.显示文摘 | AoXue Luo XingJin He SongDong Zhou YiJun Fan AoShuang Luo Ze Chun | 2009 | Carbohydrate Polymers2009，，4： | 2 |
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