|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of music therapy derived from the five elements in Traditional Chinese Medicine on post-stroke depression显示文摘OBJECTIVE: To evaluate the clinical efficacy and safety of five phase music therapy in patients with depression after ischemic stroke.METHODS: A total of 92 patients with post-stroke depression were randomly divided into the control group(32 cases), treatment group A(30 cases), and treatment group B(30 cases). All groups were given basic therapies for cerebral infarction. In addition,the control group was administerd 50 mg of oral sertraline hydrochloride daily, while treatment groups A and B received needling at Baihui(GV 20)plus acupoint injection at Yanglingquan(GB 34) daily; treatment group B also received music therapy derived from the five phases in Traditional ChineseMedicine theory twice daily. All treatments were administered for 5 d per treatment cycle for three cycles, with a 1 d interval between cycles. In all three groups, Hamilton's depression scale(HAMD-17)score and the activities of daily life(ADL) score were measured before and after treatment, and side effects were assessed with the treatment emergent symptom scale.RESULTS: The HAMD-17 score significantly decreased after treatment in all three groups, and the post-treatment reduction in HAMD-17 score was markedly greater in treatment group B than in treatment group A(P < 0.01). The ADL score significantly increased after treatment in all three groups,and the post-treatment increase in ADL score was significantly greater in treatment group B than in treatment group A(P < 0.01). The treatment emergent symptom scale score was highest in the control group, and lowest in group B, and significantly differed between the three groups(P < 0.01).CONCLUSION: Five phase music therapy plus acupoint needling and acupoint injection can improve the symptoms in patients with post-stroke depression. | Lin Facai Huang Dehong He Nana Gu Yihuang Wu Yunchuan | 2017 | Journal of Traditional Chinese Medicine2017，37，5： | 12 |
| 2 | Piglets cloned from induced pluripotent stem cells显示文摘 | Nana Fan Jijun Chen Zhouchun Shang Hongwei Dou Guangzhen Ji Qingjian Zou Lu Wu Lixiazi He Fang Wang Kai Liu Na Liu Jianyong Han Qi Zhou Dengke Pan Dongshan Yang Bentian Zhao Zhen Ouyang Zhaoming Liu Yu Zhao Lin Lin Chongming Zhong Quanlei Wang Shouqi Wang Ying Xu Jing Luan Yu Liang Zhenzhen Yang Jing Li Chunxia Lu Gabor Vajta Ziyi Li Hongsheng Ouyang Huayan Wang Yong Wang Yang Yang Zhonghua Liu Hong Wei Zhidong Luan Miguel A Esteban Hongkui Deng Huanming Yang Duanqing Pei Ning Li Gang Pei Lin Liu Yutao Du Lei Xiao Liangxue Lai | 2013 | Cell Research2013，23，1： | 12 |
| 3 | Green light-emitting diodes based on hybrid perovskite films with mixed cesium and methylammonium cations显示文摘我们报导高质量的 C 0.4 麻省 0.6 PbBr 3 有在进 perovskite 晶体的 C + 的介绍之上的将近完整的表面范围和好排放性质的薄电影。C 0.4 麻省 0.6 PbBr 3 薄电影在轻射出的二极管作为放射性的层被使用。~ 的最大的外部量效率 2.0% 为这些绿射出的设备被完成。 | Junjie Si Yang Liu Nana Wang Meng Xu Jing Li Haiping He Jianpu Wang Yizheng Jin | 2017 | Nano Research2017，10，4： | 9 |
| 4 | Nosema bombycis (Microsporidia) suppresses apoptosis in BmN cells (Bombyx mori)显示文摘Nosema bombycis (N。bombycis, Nb ) 一真菌相关并且要求在蚕引起长期的蚕胞子虫病疾病的细胞内部的寄生虫。在感染主人以后,孢子从主人房间获得精力并且幸存几天。在病原体和宿主细胞之间的这共生建议那 N。bombycis 阻止 apoptosis 和宿主细胞的反应的氧种(ROS ) 生产为它的生长和发展创造最佳的环境条件。在这研究,不同方法被用来证明那 N。bombycis 在 BmN 房间压制了 apoptosis。流动 cytometry 分析结果证明孢子在感染以后在 2 和 5 天压制了 BmN 房间的 apoptosis (P < 0.05 ) 。与放线菌素 D (ActD ) 处理相比, BmN 房间的 apoptosis 显然在孢子感染以后被减少(P < 0.01 ) 。在感染以后的 48 个小时, BmN 房间的 ROS 生产在为 6 h 的 ActD 处理以后与那相比是下面调整的。而且, N。bombycis 阻止了 apoptosomes 的形成由下面调整 apaf-1 和细胞色素 C 的表示。另外, N。bombycis 也起来调整 buffy 的表示。西方的污点分析证明孢子减少了在 48 和 98 h 柱子感染的主人细胞色素 C 的水平。因此,我们的结果建议了那 N。bombycis 禁止了主人房间的 mitochondrial apoptotic 小径为它的自己的幸存创造最佳的环境。 | Xinyi He Zhangwuke Fu Mingqian Li Han Liu Shunfeng Cai Nana Man Xingmeng Lu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，9： | 4 |
| 5 | Microcavity top-emission perovskite light-emitting diodes显示文摘Light-emitting diodes(LEDs)based on perovskites show great potential in lighting and display applications.However,although perovskite films with high photoluminescence quantum efficiencies are commonly achieved,the efficiencies of perovskite LEDs are largely limited by the low light out-coupling efficiency.Here,we show that high-efficiency perovskite LEDs with a high external quantum efficiency of 20.2% and an ultrahigh radiant exitance up to 114.9mWcm^(−2) can be achieved by employing the microcavity effect to enhance light extraction.The enhanced microcavity effect and light outcoupling efficiency are confirmed by the study of angle-dependent emission profiles.Our results show that both the optical and electrical properties of the device need to be optimized to achieve high-performance perovskite LEDs. | Yanfeng Miao Lu Cheng Wei Zou Lianghui Gu Ju Zhang Qiang Guo Qiming Peng Mengmeng Xu Yarong He Shuting Zhang Yu Cao Renzhi Li Nana Wang Wei Huang Jianpu Wang | 2020 | Light(Science & Applications)2020，9，1： | 4 |
| 6 | Factors and mechanism driving the land-use conversion in Jiangxi Province显示文摘This article explores the factors and mechanism driving the land-use conversion at regional level by developing and using an econometric approach which is called the simultaneous equations model (SEM). A case study in Jiangxi Province of China is conducted by establishing the SEM, which consists of three equations including agricultural production, land conversion of cultivated land to built-up area and land conversion of cultivated land to forest cover/grassland from 1988 to 2005. And then this paper employs the method of piecewise estimation to represent the influences of the factors such as population, society, economy, location and geophysical conditions on the process of land-use conversion in Jiangxi Province. Estimation results show that population is a predominant factor driving the land-use conversion at counties, while social and economic factors are determinant factors in the short term for the entire Jiangxi Province. Specifically, the size of agricultural population and the magnitude of agricultural input determine the agricultural production to a large extent; population size, plain area proportion at counties and land management policies together affect the direction and magnitude of conversion between cultivated land and built-up area; agricultural population proportion, terrain slope, grain production and non-agricultural industry promote the conversion of cultivated land to forest cover/grassland. Furthermore, the explored mechanism also reveals the underlying causes of the land use changes driven by a series of factors in Jiangxi Province. Finally, this paper concludes that factors proven to play an important role in driving the land-use conversion need to be considered when the land management agencies make out the land use planning to optimize the land use, expand the agricultural production, and conserve the cultivated land. | ZHAN Jinyan SHI Nana HE Shujin LIN Yingzhi | 2010 | Journal of Geographical Sciences2010，20，4： | 4 |
| 7 | Fault diagnosis of the steam turbine condenser system based on SOM neural network显示文摘 | HU Niansu HE Nana HU Sheng | 2003 | Machine Learning and Cybernetics2003，，2： | 1 |
| 8 | Alginate/ Graphene Oxide fibers with Enhanced Mechanical Strength Pre- pared by Wet Spinning显示文摘 | He Yongqiang Zhang Nana Gong Qiaojuan | 2012 | Carbohydrate Polymers2012，88，： | 1 |
| 9 | Alginate/graphene oxide fibers with enhanced mechanical strength prepared by wet spinning显示文摘 | He Yongqiang Zhang Nana Gong Qiaojuan | 2012 | Carbohydrate Polymers2012，88，3： | 1 |
| 10 | Generation of gene-target dogs using CRISPR/Cas9 system显示文摘Dear Editor,Dogs(Canis familiaris)serve as human companions and are raised to herd livestock,aid hunters,guard homes,perform police and rescue work,and guide the blind.Dogs exhibit close similarities to humans in terms of metabolic,physiological,and anatomical characteristics,and thus are ideal genetic and clinical models to study human diseases(Tsai et al.,2007).Gene target technology is a powerful tool to create new strains of animals with favorable traits.However,thus far,gene-target dogs have not been developed due to their unique species-specific reproductive characteristics,which limits the applications of dogs especially in the field of biomedical research.Recently,clustered regularly interspaced short palindromic repeats(CRISPRs)/CRISPR-associated(Cas)9 system was applied to edit specific genes with a high efficiency(Cong et al.,2013;Mali et al.,2013).Here we attempt to explore the feasibility of producing gene knockout(KO)dogs by using this technology.Beagle dog,the most widely used breed in biomedical research,was used as our animal model.Myostatin(MSTN)was chosen as the first gene of interest. | Qingjian Zou Xiaomin Wang Yunzhong Liu Zhen Ouyang Haibin Long Shu Wei Jige Xin Bentian Zhao Sisi Lai Jun Shen Qingchun Ni Huaqiang Yang Huilin Zhong Li Li Minhua Hu Quanjun Zhang Zhidong Zhou Jiaxin He Quanmei Yan Nana Fan Yu Zhao Zhaoming Liu Lin Guo Jiao Huang Guanguan Zhang Jun Ying Liangxue Lai Xiang Gao | 2015 | Journal of Molecular Cell Biology2015，7，6： | 1 |
| 11 | Alginate/Graphene Oxide Fibers with Enhanced Mechanical Strength Prepared by Wet Spinning显示文摘 | He Yongqiang Zhang Nana Gong Qiaojuan | 2012 | Carbohydrate Polymers2012，88，3： | 1 |
| 12 | Studies on the Preparation of Stable PSt Latex in the Presence of Cyclodextrins and a Small Amount of Surfactant显示文摘 | Nana Huang Yuhong Zhang Meigui Zhao Peixin He | 2012 | Journal of Dispersion Science and Technology2012，，11： | 1 |
| 13 | Field-portable ratiometric fluorescence imaging of dual-color label-free carbon dots for uranyl ions detection with cellphone-based optical platform显示文摘Under the public spotlight,uranyl(UO22+)ions has attracted considerable attention for the extreme radioactive and chemical toxicity to ourselves and our environment.Herein,we present a simple and effective ratiometric fluorescence imaging method for the visualizing and quantitative detection UO22+ions by cellphone-based optical platform.The sensing solution was prepared by mixing label-free red carbon dots(r-CDs)and blue carbon dots(b-CDs)together with a fixed photoluminescence intensity ratio of 4:1.When UO22+ions were added,the fluorescence of r-CDs can be selectively quenched,while the fluorescence of b-CDs remains stable without spectral cha nges.With the gradually increase the amounts of UO22+ions,the different response of dual-color CDs resulted in a signification color evolution from deep red to dark purple under the ultraviolet(UV)light illumination.Then,a cellphone-based optical platform was constructed for directly imaging the color change of the samples,and the built-in Colorpicker APP quickly output the red,green and blue(RGB)channel values of these images within one second.Interesting,there was a linear relationship between the ratio of red and blue(R/B)channel values and UO22+ions concentration from 0μmol/L to 30.0μmol/L(R^2=0.92804)with the detection limit of^8.15μmol/L(signal-to-noise ratio of 3).In addition,the optical platform has also been applied to the quantification of UO22+ions in tap water and river water sample.With the advantage of low-cost,portable,easy to operation,we anticipate that this method would greatly improve the accessibility of UO22+ions detection even in resource-limited areas. | Jingjing Qian Nana Cao Jian Zhang Jinjin Hou Qian Chen Cheng Zhang Yudie Sun Shengjun Liu Lifang He Kui Zhang Haibo Zhou | 2020 | Chinese Chemical Letters2020，31，11： | 0 |
| 14 | An Insight of the First Community Infected COVID-19 Patient in Beijing by Imported Case: Role of Deep Learning-Assisted CT Diagnosis显示文摘In the era of coronavirus disease 2019(COVID-19)pandemic,imported COVID-19 cases pose great challenges to many countries.Chest CT examination is considered to be complementary to nucleic acid test for COVID-19 detection and diagnosis.Wie report the first community infected COVID-19 patient by an imported case in Beijing,which manifested as nodular lesions on chest CT imaging at the early stage.Deep Learning(DL)-based diagnostic systems quantitatively monitored the progress of pulmonary lesions in 6 days and timely made alert for suspected pneumonia,so that prompt medical isolation was taken.The patient was confirmed as COVID-19 case after nucleic acid test,for which the community transmission was prevented timely.The roles of DL-assisted diagnosis in helping radiologists screening suspected COVID cases were discussed. | Dasheng Li Dawei Wang Nana Wang Haiwang Xu He Huang Jianping Dong Chen Xia | 2021 | Chinese Medical Sciences Journal2021，36，1： | 0 |
| 15 | High-temperature ferromagnetic metallic phase in LaMnO_(3)/Sr_(3)Al_(2)O_(6)heterostructure显示文摘To achieve a flexible single-crystal multifunctional membrane,the freestanding process of a rigid epitaxial transition metal oxide thin film via a buffered water-dissolution sacrificial layer has attracted reasonable attentions.Owing to the difference in chemical potential,specific element affinity,and lattice constant between the target membrane and the sacrificial layer,the freestanding process may cause an indelible change of physics property once the target thin film is sensitive to the above factors.Here,the heterostructures composed of the generally adopted sacrificial layer Sr_(3)Al_(2)O_(6)(SAO)and LaMnO_(3)(LMO)have been systematically investigated.The electrical and magnetic properties of LMO show extreme sensitivity to the thickness of SAO(tSAO).Then we have also found that LMO/SAO heterostructures can exhibit the coexistence of two ferromagnetic phases,the significantly enhanced Curie temperature~342 K,and the large magnetoresistance-23.3%at 300 K,which is similar to the optimal-doped manganite such as La_(2/3)Sr_(1/3)MnO_(3).X-ray diffraction results show that continuously tunable strain from out-of-plane tension to relaxation and then to compression can be generated by adjusting tSAO.This strain can stabilize the migrated oxygen from LMO to SAO,which is induced by the large oxygen affinity difference between Bsite Mn and Al.It is believed that these unexpected electrical/magnetic phenomena are originated from the combined effects of interfacial element diffusion and strain.Our study provides a strategy for designing new magnetic phases,and a reference for the fundamental understanding of strongly correlated transition metal oxide systems in the freestanding process. | Di Wang Bin He Jinrui Guo Qixiang Wang Chaoqun Shi Yue Han Hong Fang Jie Wang Nana Zhang Peng Zhang Yanan Chen Changwen Zhang Weiming Lü Shishen Yan | 2022 | Journal of Materials Science & Technology2022，，24： | 0 |
| 16 | Scutellarin prevents acute alcohol-induced liver injury via inhibiting oxidative stress by regulating the Nrf2/HO-1 pathway and inhibiting inflammation by regulating the AKT,p38 MAPK/NF-κB pathways显示文摘Alcoholic liver disease(ALD)is the most frequent liver disease worldwide,resulting in severe harm to personal health and posing a serious burden to public health.Based on the reported antioxidant and anti-inflammatory capacities of scutellarin(SCU),this study investigated its protective role in male BALB/c mice with acute alcoholic liver injury after oral administration(10,25,and 50 mg/kg).The results indicated that SCU could lessen serum alanine aminotransferase(ALT)and aspartate aminotransferase(AST)levels and improve the histopathological changes in acute alcoholic liver;it reduced alcohol-induced malondialdehyde(MDA)content and increased glutathione peroxidase(GSH-Px),catalase(CAT),and superoxide dismutase(SOD)activity.Furthermore,SCU decreased tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),and IL-1βmessenger RNA(mRNA)expression levels,weakened inducible nitric oxide synthase(iNOS)activity,and inhibited nucleotide-binding oligomerization domain(NOD)-like receptor protein 3(NLRP3)inflammasome activation.Mechanistically,SCU suppressed cytochrome P450 family 2 subfamily E member 1(CYP2E1)upregulation triggered by alcohol,increased the expression of oxidative stress-related nuclear factor erythroid 2-related factor 2(Nrf2)and heme oxygenase-1(HO-1)pathways,and suppressed the inflammation-related degradation of inhibitor of nuclear factor-κB(NF-κB)-α(IκBα)as well as activation of NF-κB by mediating the protein kinase B(AKT)and p38 mitogen-activated protein kinase(MAPK)pathways.These findings demonstrate that SCU protects against acute alcoholic liver injury via inhibiting oxidative stress by regulating the Nrf2/HO-1 pathway and suppressing inflammation by regulating the AKT,p38 MAPK/NF-κB pathways. | Xiao ZHANG Zhicheng DONG Hui FAN Qiankun YANG Guili YU Enzhuang PAN Nana HE Xueqing LI Panpan ZHAO Mian FU Jingquan DONG | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，7： | 0 |
| 17 | Tunneling, Information Asymmetry, and Private Placement Discounts显示文摘私人放置成为了公平为管理者,列出的公司,和投资者供的一个日益重要的方法。这份报纸分析基于控制股东影响私人放置折扣的因素机会主义的行为和信息不对称现象。我们的调查结果显示订户的类型是私人放置折扣的一个关键决定因素,特别地当订户是控制股东时。在列出的公司和投资者之间的不对称的信息是另一个重要决定因素:越高信息不对称现象的度,私人放置打折越多 greater。 | Dan He Nana Wang | 2012 | Frontiers of Business Research in China2012，6，3： | 0 |
| 18 | Computation Tree Logic Model Checking of Multi-Agent Systems Based on Fuzzy Epistemic Interpreted Systems显示文摘Model checking is an automated formal verification method to verify whether epistemic multi-agent systems adhere to property specifications.Although there is an extensive literature on qualitative properties such as safety and liveness,there is still a lack of quantitative and uncertain property verifications for these systems.In uncertain environments,agents must make judicious decisions based on subjective epistemic.To verify epistemic and measurable properties in multi-agent systems,this paper extends fuzzy computation tree logic by introducing epistemic modalities and proposing a new Fuzzy Computation Tree Logic of Knowledge(FCTLK).We represent fuzzy multi-agent systems as distributed knowledge bases with fuzzy epistemic interpreted systems.In addition,we provide a transformation algorithm from fuzzy epistemic interpreted systems to fuzzy Kripke structures,as well as transformation rules from FCTLK formulas to Fuzzy Computation Tree Logic(FCTL)formulas.Accordingly,we transform the FCTLK model checking problem into the FCTL model checking.This enables the verification of FCTLK formulas by using the fuzzy model checking algorithm of FCTL without additional computational overheads.Finally,we present correctness proofs and complexity analyses of the proposed algorithms.Additionally,we further illustrate the practical application of our approach through an example of a train control system. | Xia Li Zhanyou Ma Zhibao Mian Ziyuan Liu Ruiqi Huang Nana He | 2024 | Computers, Materials & Continua2024，78，3： | 0 |
| 19 | Rapid and sensitive detection of Oncorhynchus mykiss adulteration in Salmo salar by recombinase polymerase amplification combined with lateral flow strip显示文摘Oncorhynchus mykiss,a kind of freshwater fish,belongs to the Salmonidae family and Oncorhynchus genus[1].O.mykiss is farmed in more than 20 cities in China,being one of the most common cold-water farming fish.The wide range of O.mykiss may attribute to its rapid growth and tolerance of different environmental conditions.Salmo salar attracts customers’interest for its delicious taste and high nutrient contents.However,wild S.salar supply is far less than high demands,and artificial breeding faces difficulties in yield and cost.External morphological characteristics can distinguish full-fledged fish,but it is difficult to distinguish after processing with pigments for the white and blue O.mykiss meat displaying orange color and texture[2].The food industry provides cheaper O.mykiss adulteration in S.salar,infringing consumers’rights and interests.Moreover,farmed O.mykiss in fresh water may risk parasite infection,and customers who eat raw food face food safety concerns[3]. | Qiankun Yang Xia Liu Lei Wang Guili Yu Haitao Yang Hang Fu Xueqing Li Nana He Hong Yu Jingquan Dong | 2022 | Acta Biochimica et Biophysica Sinica2022，54，7： | 0 |
| 20 | Potentials of miR-9-5p in promoting epileptic seizure and improving survival of glioma patients显示文摘Background Epilepsy affects over 70 million people worldwide;however,the underlying mechanisms remain unclear.MicroRNAs(miRNAs)have essential functions in epilepsy.miRNA-9,a brain-specific/enriched miRNA,plays a role in various nervous system diseases and tumors,but whether miRNA-9 is involved in epilepsy and glioma-associated epilepsy remains unknown.Therefore,we aimed to explore the potential role of miR-9-5p in seizures and its effect on the survival of glioma patients,in order to provide new targets for the treatment of epilepsy and glioma.Methods The YM500v2 database was used to validate the expression of hsa-miR-9-5p in tissues.Moreover,qRT-PCR was performed to investigate the expression of miR-9-5p in temporal lobe epilepsy patients and rats with lithium-pilocarpine-induced seizures.Recombinant adeno-associated virus containing miR-9-5p was constructed to overexpress miR-9-5p in vivo.The effects of miR-9-5p on the behavior and electroencephalographic activities of the lithium-pilocarpine rat model of epilepsy were tested.Bioinformatics analysis was used to predict the targets of miR-9-5p and explore its potential role in epilepsy and glioma-associated epilepsy.Results The expression of miR-9-5p increased at 6 h and 7 days after lithium-pilocarpine-induced seizures in rats.Overexpression of miR-9-5p significantly shortened the latency of seizures and increased seizure intensity at 10 min and 20 min after administration of pilocarpine(P<0.05).Predicted targets of miR-9-5p were abundant and enriched in the brain,and affected various pathways related to epilepsy and tumor.Survival analysis revealed that overexpression of miR-9-5p significantly improved the survival of patients from with low-grade gliomas and glioblastomas.The involvement of miR-9-5p in the glioma-associated epileptic seizures and the improvement of glioma survival may be related to multiple pathways,including the Rho GTPases and hub genes included SH3PXD2B,ARF6,and ANK2.Conclusions miR-9-5p may play a key role in promoting epileptic seizures and improving glioma survival,probably through multiple pathways,including GTPases of the Rho family and hub genes including SH3PXD2B,ARF6 and ANK2.Understanding the roles of miR-9-5p in epilepsy and glioma and the underlying mechanisms may provide a theoretical basis for the diagnosis and treatment of patients with epilepsy and glioma. | Shenglin Wang Xuzhi He Nana Bao Mingyue Chen Xiaomi Ding Ming Zhang Li Zhao Shunxian Wang Guohui Jiang | 2022 | Acta Epileptologica2022，5，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员