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| 1 | Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI显示文摘 | Wang L Zang Y He Y Liang M Zhang X Tian L Wu T Jiang T Li K | 2006 | 中国生物学文摘2006，20，10： | 84 |
| 2 | On the combined effect of soil fertility and topography on tree growth in subtropical forest ecosystems—a study from SE China显示文摘Aims The aim of our research was to understand small-scale effects of topography and soil fertility on tree growth in a forest biodiversity and ecosystem functioning(BEF)experiment in subtropical SE China.Methods Geomorphometric terrain analyses were carried out at a spatial resolution of 5×5 m.Soil samples of different depth increments and data on tree height were collected from a total of 566 plots(667 m2 each).The soils were analyzed for carbon(soil organic carbon[SOC]),nitrogen,acidity,cation exchange capacity(CEC),exchangeable cations and base saturation as soil fertility attributes.All plots were classified into geomorphological units.Analyses of variance and linear regressions were applied to all terrain,soil fertility and tree growth attributes.Important Findings In general,young and shallow soils and relatively small differences in stable soil properties suggest that soil erosion has truncated the soils to a large extent over the whole area of the experiment.This explains the concurrently increasing CEC and SOC stocks downslope,in hollows and in valleys.However,colluvial,carbon-rich sediments are missing widely due to the convexity of the footslopes caused by uplift and removal of eroded sediments by adjacent waterways.The results showed that soil fertility is mainly influenced by topography.Monte-Carlo flow accumulation(MCCA),curvature,slope and aspect significantly affected soil fertility.Furthermore,soil fertility was affected by the different geomorphological positions on the experimental sites with ridge and spur positions showing lower exchangeable base cation contents,especially potassium(K),due to leaching.This geomorphological effect of soil fertility is most pronounced in the topsoil and decreases when considering the subsoil down to 50 cm depth.Few soil fertility attributes affect tree height after 1-2 years of growth,among which C stocks proved to be most important while pH_(KCl)and CEC only played minor roles.Nevertheless,soil acidity and a high proportion of Al on the exchange complex affected tree height even after only 1-2 years growth.Hence,our study showed that forest nutrition is coupled to a recycling of litter nutrients,and does not only depend on subsequent supply of nutrients from the mineral soil.Besides soil fertility,topography affected tree height.We found that especially MCCA as indicator of water availability affected tree growth at small-scale,as well as aspect.Overall,our synthesis on the interrelation between fertility,topography and tree growth in a subtropical forest ecosystem in SE China showed that topographic heterogeneity lead to ecological gradients across geomorphological positions.In this respect,small-scale soil-plant interactions in a young forest can serve as a driver for the future development of vegetation and biodiversity control on soil fertility.In addition,it shows that terrain attributes should be accounted for in ecological research. | Thomas Scholten Philipp Goebes Peter Kühn Steffen Seitz Thorsten Assmann Jürgen Bauhus Helge Bruelheide Francois Buscot Alexandra Erfmeier Markus Fischer Werner Härdtle Jin-Sheng He Keping Ma Pascal A.Niklaus Michael Scherer-Lorenzen Bernhard Schmid Xuezheng Shi Zhengshan Song Goddert von Oheimb Christian Wirth Tesfaye Wubet Karsten Schmidt | 2017 | Journal of Plant Ecology2017，10，1： | 22 |
| 3 | Assessing Vulnerability to Drought Based on Exposure,Sensitivity and Adaptive Capacity:A Case Study in Middle Inner Mongolia of China显示文摘In this paper,we proposed a framework for evaluating the performance of ecosystem strategies prepared for enhancing vulnerability reduction in the face of hazards due to climate change.The framework highlights the positive effects of human activities in the coupled human and natural system(CHANS) by introducing adaptive capacity as an evaluation criterion.A built-in regional vulnerability to a certain hazard was generated based upon interaction of three dimensions of vulnerability:exposure,sensitivity and adaptive capacity.We illustrated the application of this framework in the temperate farming-grazing transitional zone in the middle Inner Mongolia of the northern China,where drought hazard is the key threat to the CHANS.Specific indices were produced to translate such climate variance and social-economic differences into specific indicators.The results showed that the most exposed regions are the inner land areas,while counties located in the eastern part are potentially the most adaptive ones.Ordos City and Bayannur City are most frequently influenced by multiple climate variances,showing highest sensitivity.Analysis also indicated that differences in the ability to adapt to changes are the main causes of spatial differences.After depiction of the spatial differentiations and analysis of the reasons,climate zones were divided to depict the differences in facing to the drought threats.The climate zones were shown to be similar to vulnerability zones based on the quantitative structure of indexes drafted by a triangular map.Further analysis of the composition of the vulnerability index showed that the evaluation criteria were effective in validating the spatial differentiation but potentially ineffective because of their limited time scope.This research will be a demonstration of how to combine the three dimensions by quantitative methods and will thus provide a guide for government to vulnerability reduction management. | LIU Xiaoqian WANG Yanglin PENG Jian Ademola K BRAIMOH YIN He | 2013 | Chinese Geographical Science2013，23，1： | 17 |
| 4 | Induction of mucosal and systemic immune response by single-dose oral immunization with biodegradable microparticles containing DNA encoding HBsAg显示文摘 | He XW Wang F Jiang L Li J Liu SK Xiao ZY Jin XQ Zhang YN He Y Li K Guo YJ Sun SH | 2005 | 第二军医大学学报2005，26，10： | 5 |
| 5 | Chemical Constituents in Extracts from Leaves of Lantana trifolia and Their In Vitro Anti-oxidative Activity显示文摘Objective To isolate, purify, and analyze the anti-oxidants from the leaves of Lantanatrifolia. Methods The anti-oxidative activities of the crude extracts from liquid-liquid extraction of L. trifolia leaves were assayed by 1,1-diphenyl-2-picrylhydrazyl(DPPH) method to assess their radical scavenging and reducing abilities. The total flavonoidsand phenol contents in the ethyl acetate fraction were determined by colorimetric and Folin–Ciocalteu methods, respectively. Chemical constituents were isolated from the ethyl acetate fraction and repeatedly purified using silica gel, Sephadex LH-20 column chromatography, and HPLC, respectively. The chemical structures isolated were identified by spectral analysis and chemical evidence. Results Ethyl acetate partition from liquid-liquid extraction exhibited the highest anti-oxidative activity with an IC50 value of 4.94 μg/mL, close to that of the standard(vitamin C, VC, 4.23 μg/mL). The extract was proved to contain total flavonoids and phenol contents with values of(39.0 ± 1.6) and(29.27 ± 1.46) mg/g, respectively. Six compounds were isolated and identified as kaempferol-3,7-dimethyl ether(1), verbascoside(2), apigenin(3), umuhengerin(4), ladanetin(5), and scutellarein-7-O-β-D-apiofuranoside(6).Conclusion The ethyl acetate extract from the leaves of L. trifolia possesses the potent anti-oxidative and free radical scavenging activities which are directly proportional to the concentration of phenolic contents. The anti-oxidative activity of the extract from the leaves of L. trifolia is due to its proton donating ability that converts free radicals to more stable products and terminates chain reactions. Compound 1 is isolated from the plants of Lantana Linn. for the first time. The mechanisms may be related to the therapeutic benefits of the certain traditional claims of wild L. trifolia. | Palmer Sivoko Imbenzi Yong-zhi He Zhi-xue Yan Eric Kibagendi Osoro Peter K Cheplogoi | 2014 | Chinese Herbal Medicines2014，6，3： | 4 |
| 6 | Prevalence of the metabolic syndrome and overweight among adults in China显示文摘 | Dongfeng Gu Kristi Reynolds Xigui Wu Jing Chen Xiufang Duan Robert F Reynolds Paul K Whelton Jiang He | 2005 | 2005 (9468)2005，，9468： | 3 |
| 7 | Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI显示文摘 | Wang L Zang Y He Y Liang M Zhang X Tian L Wu T Jiang T Li K | 2006 | 中国生物学文摘2006，20，8： | 3 |
| 8 | Loss of MeCP2 in cholinergic neurons causes part of RTT- like phenotypes via α7 receptor in hippocampus显示文摘 | Ying Zhang Shu-Xia Cao Peng Sun Hai-Yang He Ci-Hang Yang Xiao-Juan Chen Chen-Jie Shen Xiao-Dong Wang Zhong Chen Darwin K Berg Shumin Duan Xiao-Ming Li | 2016 | Cell Research2016，26，6： | 3 |
| 9 | Noncontrast-enhanced MRI-based Noninvasive Score for Portal Hypertension(CHESS1802):An International Multicenter Study显示文摘Background and Aims:This study aimed to determine the performance of the non-invasive score using noncontrastenhanced MRI(CHESS-DIS score)for detecting portal hy-pertension in cirrhosis.Methods:In this international multicenter,diagnostic study(ClinicalTrials.gov,NCT03766880),patients with cirrhosis who had hepatic venous pressure gradient(HVPG)measurement and noncontrast-enhanced MRI were prospectively recruited from four university hospitals in China(n=4)and Turkey(n=1)between December 2018 and April 2019.A cohort of patients was retrospectively recruited from a university hospital in Italy between March 2015 and November 2017.After segmentation of the liver on fat-suppressed T1-weighted MRI maps,CHESS-DIS score was calculated automatically by an in-house developed code based on the quantification of liver surface nodularity.Results:A total of 149 patients were included,of which 124 were from four Chinese hospitals(training cohort)and 25 were from two international hospitals(validation cohort).A positive correlation between CHESS-DIS score and HVPG was found with the correlation coefficients of 0.36(p<0.0001)and 0.55(p<0.01)for the training and validation cohorts,respectively.The area under the receiver operating characteristic curve of CHESS-DIS score in detection of clinically significant portal hypertension(CSPH)was 0.81 and 0.9 in the training and validation cohorts,respectively.The intra-class correlation coefficients for assessing the inter-and intra-observer agreement were 0.846 and 0.841,respectively.Conclusions:A non-invasive score using noncontrast-enhanced MRI was developed and proved to be significantly correlated with invasive HVPG.Besides,this score could be used to detect CSPH in patients with cirrhosis. | Yanna Liu Tianyu Tang NecatiÖrmeci Yifei Huang Jitao Wang Xiaoguo Li Zhiwei Li Weimin An Dengxiang Liu Chunqing Zhang Changchun Liu Jinqiang Liu Chuan Liu Guangchuan Wang Cristina Mosconi Alberta Cappelli Antonio Bruno Seray Akçalar EmrecanÇelebioğlu EvrenÜstüner Sadık Bilgiç Zeynep Ellik ÖzgünÖmer Asiller Lei Li Haijun Zhang Ning Kang Dan Xu Ruiling He Yan Wang Yang Bu Ye Gu Shenghong Ju Rita Golfieri Xiaolong Qi | 2021 | Journal of Clinical and Translational Hepatology2021，9，6： | 3 |
| 10 | 飞秒激光辅助的白内障手术发展现状显示文摘白内障激光手术始于上世纪70年代:1975年应用694 nm Q开关红宝石激光器,随后用193~351nm紫外波段激光,80年代,开始应用红外波段激光。Nd∶YAG激光最早应用于人工晶体眼患者的后囊切开术,也曾用于前囊切开术,但因炎症。 | He LM Sheehy K Culbertson W 张佳莹 | 2011 | 中国激光医学杂志2011，20，5： | 2 |
| 11 | Geographic variations in the prevalence, awareness, treatment and control of hypertension in China显示文摘 | Kristi Reynolds Dongfeng Gu Paul Muntner Xigui Wu Jing Chen Guanyong Huang Xiufang Duan Paul K Whelton Jiang He | 2003 | Journal of Hypertension2003，，7： | 2 |
| 12 | Prevalence of the metabolic syndrome and overweight among adults in China显示文摘 | Dongfeng Gu Kristi Reynolds Xigui Wu Jing Chen Xiufang Duan Robert F Reynolds Paul K Whelton Jiang He | 2005 | The Lancet . 2005 (9468)2005，，9468： | 2 |
| 13 | Global burden of hypertension: analysis of worldwide data显示文摘 | Patricia M Kearney Megan Whelton Kristi Reynolds Paul Muntner Paul K Whelton Jiang He | 2005 | The Lancet2005，，9455： | 2 |
| 14 | Global burden of hypertension: analysis of worldwide data显示文摘 | Patricia M Kearney Megan Whelton Kristi Reynolds Paul Muntner Paul K Whelton Jiang He | 2005 | The Lancet . 2005 (9455)2005，，9455： | 2 |
| 15 | Global burden of hypertension: analysis of worldwide data显示文摘 | Patricia M Kearney Megan Whelton Kristi Reynolds Paul Muntner Paul K Whelton Jiang He | 2005 | The Lancet2005，，9455： | 2 |
| 16 | Global burden of hypertension: analysis of worldwide data显示文摘 | Patricia M Kearney Megan Whelton Kristi Reynolds Paul Muntner Paul K Whelton Jiang He | 2005 | 2005 (9455)2005，，9455： | 2 |
| 17 | Synthesis and crystal structure of K4H2·18H2O显示文摘 | Ye SR Shan Y K He M Y | 2002 | Zeitschrift fur Kristallographie NCS2002，217，： | 2 |
| 18 | Liquid-Phase Microextraction in a Single Drop of Organic Solvent by Using a Conventional Microsyringe显示文摘 | He Y Lee H K | 1997 | Anal Chem1997，69，： | 2 |
| 19 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 20 | Passive and hybrid control systems for seismic protection of a benchmark cable-stayed bridge 显示文摘 | He W L Aqrawal A K | 2007 | Structural Control and Health Monitoring2007，14，1： | 1 |
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