|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ideal cardiovascular health and incidence of atherosclerotic cardiovascular disease among Chinese adults:the China-PAR project显示文摘Existing evidence on the relationship between cardiovascular health(CVH) metrics and cardiovascular disease(CVD) was primarily derived from western populations. We aimed to evaluate the benefits of ideal CVH metrics on preventing incident atherosclerotic CVD(ASCVD) in Chinese population. This study was conducted among 93,987 adults from the China-PAR project(Prediction for ASCVD Risk in China) who were followed up until 2015. Cox proportional hazard regression models were used to estimate the hazard ratios(HRs) and their corresponding 95% confidence intervals(CIs) of CVH metrics for the risk of ASCVD, including coronary heart disease(CHD), stroke and ASCVD death. We further estimated the population-attributable risk percentage(PAR%) of these metrics in relation to each outcome. We observed gradient inverse associations between the number of ideal CVH metrics and ASCVD incidence. Compared with participants having ≤2 ideal CVH metrics, the multivariable-adjusted HRs(95% CIs) of ASCVD for those with 3, 4, 5, 6 and 7 ideal CVH metrics were 0.83(0.74–0.93), 0.66(0.59–0.74), 0.55(0.48–0.61), 0.44(0.38–0.50) and 0.24(0.18–0.31), respectively(P for trend <0.0001). Approximately 62.1% of total ASCVD, 38.7% of CHD, 66.4% of stroke, and 60.5% of ASCVD death were attributable to not achieving all the seven ideal CVH metrics. After adjusting effects of ideal health factors, having four ideal health behaviors could independently bring adults health benefits in preventing 17.4% of ASCVD, 18.0% of CHD, 16.7% of stroke, and 10.1% of ASCVD death. Among all the seven CVH metrics, to keep with ideal blood pressure(BP) implied the largest public health gains against various ASCVD events(PAR% between 33.0% and 47.2%), while ideal diet was the metric most difficult to be achieved in the long term. Our study indicates that the more ideal CVH metrics adults have, the less ASCVD burden there is in China. Special efforts of health education and behavior modification should be made on keeping ideal BP and dietary habits in general Chinese population to prevent the epidemic of ASCVD. | Chao Han Fangchao Liu Xueli Yang Jichun Chen Jianxin Li Jie Cao Ying Li Chong Shen Ling Yu Zhendong Liu Xianping Wu Liancheng Zhao Dongshen Hu Xiangfeng Lu Xigui Wu Dongfeng Gu | 2018 | Science China(Life Sciences)2018，61，5： | 60 |
| 2 | Predicting lifetime risk for developing atherosclerotic cardiovascular disease in Chinese population:the China-PAR project显示文摘Evidence on the lifetime risk for atherosclerotic cardiovascular disease(ASCVD) is insufficient;yet,estimating an individual's lifetime risk allows for a comprehensive assessment of ASCVD burden.We developed and validated lifetime risk prediction equations for ASCVD using four large and ongoing prospective cohorts of Chinese,the China-PAR project(Prediction for ASCVD Risk in China).Sexspecific equations were developed using two cohorts(as the derivation cohort) of 21,320 participants.Two other independent cohorts with 14,123 and 70,838 participants were used for their external validation,respectively.We evaluated both calibration and discrimination measures for model performance.Furthermore,we estimated ASCVD-free years lost or excess absolute risk attributable to high 10-year risk(!10.0%) and/or high lifetime risk(!32.8%).After 12.3 years' follow-up of the derivation cohort,1048 ASCVD events and 1304 non-ASCVD deaths were identified.Our sex-specific equations had good internal validation,with discriminant C statistics of 0.776(95% confidence interval [CI]:0.757–0.794) and 0.801(95% CI:0.778–0.825),and calibration χ~2 of 9.2(P = 0.418) and 5.6(P = 0.777) for men and women,respectively.Good external validation was also demonstrated with predicted rates closely matched to the observed ones.Compared with men having both low 10-year and low lifetime risk,men would develop ASCVD 3.0,4.6 and 8.6 years earlier if they had high 10-year risk alone,high lifetime risk alone,or both high 10-year and high lifetime risk at the index age of 35 years,respectively.We developed wellperformed lifetime risk prediction equations that will help to identify those with the greatest potential to avert ASCVD burden after implementation of innovative clinical and public health interventions in China. | Fangchao Liu Jianxin Li Jichun Chen Dongsheng Hu Ying Li Jianfeng Huang Xiaoqing Liu Xueli Yang Jie Cao Chong Shen Ling Yu Zhendong Liu Xianping Wu Liancheng Zhao Xigui Wu Dongfeng Gu Xiangfeng Lu | 2018 | Science Bulletin2018，63，12： | 30 |
| 3 | The expression of cyclooxygenase-2 (COX-2) and p16 in non-Hodgkin's lymphomas and its clinical significance显示文摘目的将在 non-Hodgkin 的淋巴瘤(NHL ) 和他们与它的开始和进步的关系调查 cyclooxygenase-2 (COX-2 ) 和 p16 蛋白质的表示。COX-2 和 p16 蛋白质的表达式被流动血细胞计数与非恶意的疾病从 60 个 NHL 病人和 10 个控制病人在淋巴结织物学习的方法。结果在 NHL 纸巾的 COX-2 蛋白质表示的积极的率(63.3% , 38/60 ) 在在纸巾的正常单桅单甲板平底船比那高(0, 0/10 ) 。差别在二个组之间是重要的(P <
0.01 ) 。COX-2 蛋白质的表示与 NHL 的临床的阶段被联系。在舞台我 + II 病人,它显著地更低(35.0%+54.6%) 比那在阶段 III + IV 病人(84.6%+87.5%)(P <
0.01 ) 。在不同性别,变老,恶意的度,国际新闻学会等级,额外的节的参与和 B 症状组织的肿瘤, COX-2 表示的差别不是统计上重要的(P >
0.05 ) 。p16 蛋白质表示的积极的率(41.7% , 25/60 ) 在正常淋巴瘤在 NHL' 是比那统计上低的(100% , 10/10 )(P <
0.01 ) 。p16 蛋白质的表示与 NHL 的恶意的度有关。在低恶意的度纸巾的 p16 蛋白质的积极的率(64.7% , 11/17 ) 在高恶意的度纸巾比那高(14.3% , 2/14 )(P <
0.05 ) 。在不同性别,年龄,国际新闻学会等级,额外的节的参与,临床的阶段和 B 症状的 NHL 纸巾的 p16 蛋白质的积极的率不是统计上重要的(P >
0.05 ) 。在 COX-2 积极病人的 p16 蛋白质表示是 47.4%(18/38 ) ,并且在否定病人,它是 31.8%(7/22 ) 。有没有统计上他们之间的差别(P >
0.05 ) 。在那里揭示的关联分析不是在 COX-2 和 p16 蛋白质的表示之间的关联。COX-2 和 p16 蛋白质都可以与开始有关系并且 NHL 进行的结论。在 NHL 的 COX-2 蛋白质的表示可以是差的预示的指示物。COX-2 和 p16 蛋白质可能在 NHL 的开始和进步有不同机制。他们的关系第一在这篇文章被提出并且需要推进学习。 | Xigui Yang Huazhi Zhang Ling Wei Liya Jia | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，2： | 4 |
| 4 | Mechanical model for controlling floor heave in deep roadways with U-shaped steel closed support显示文摘Open U-shaped steel arch supports are commonly used in large-section static-pressure roadways in coal mines that are more than 900 m deep;however,it is very difficult to control floor heave of roadways.In this paper,a U-shaped steel closed support with an inverted U-shaped steel arch in the floor is proposed as a method for improving the support effect of the surrounding rock during the process of floor heaving.This research established a mechanical model for the U-shaped steel closed support,and determined the reaction forces at the connection of a camber angle.Using the limit load method calculated the critical buckling load of the inverted U-shaped steel arch,and use of a strength check method tested the strength of the U-shaped steel material.A numerical simulation was conducted using the finite difference software FLAC3 D.The simulation results show that the U-shaped steel closed support is able to control the floor heave of roadways,which is successfully used in the West 11-2 development roadway of the Zhuji Mine in the Huainan mining area in China.The cumulative floor heave over two years was less than50 mm. | Zhao Yiming Liu Na Zheng Xigui Zhang Nong | 2015 | International Journal of Mining Science and Technology2015，25，5： | 4 |
| 5 | Prevalence of the metabolic syndrome and overweight among adults in China显示文摘 | Dongfeng Gu Kristi Reynolds Xigui Wu Jing Chen Xiufang Duan Robert F Reynolds Paul K Whelton Jiang He | 2005 | 2005 (9468)2005，，9468： | 3 |
| 6 | Comparative study on microstructure of β-Ni(OH)_(2) as cathode material for Ni-MH battery显示文摘Microstructures such as micro-strain, crystallite as well as stacking faults can result in broadening of X-ray diffraction lines. Based on least square principle, new com- putation method and programs, which can separate the two-fold broadening effect caused by crystallite/stacking faults and which can separate the three-fold broadening effect caused by crystallite/residual stress/stacking faults, have been proposed. As a result, mi- cro-strain and crystallite sizes as well as stacking fault probability can be calculated re- spectively and investigated in detail. Then the microstructures of β-Ni(OH)2 are investi- gated by means of these methods. The main results are as follows: 1) The shape and size of crystallite as well as stacking fault probability of raw β-Ni(OH)2 are dependent on its preparation technique. 2) Activation changes the microstructure of β-Ni(OH)2. It transforms the crystallite shape from short-fat cylinder into polyhedrons or nearly equiaxial grains. Activation also alters the residual strain states and stacking fault probability. 3) After charge-discharge and cycle-lifetime testing, the crystallites of β-Ni(OH)2 are fined further and its residual strain and fault probability were alternated. The extent of these effects are dependent on circulating conditions. 4) Calcium additive in β-Ni(OH)2 restrains grain fining process and turns twin fault into deformation fault. 5) Comprehensive analysis reveals that micro structural parameters of β-Ni(OH)2 are correlated with some performance of Ni-MH battery. | LOU Yuwan YANG Chuanzheng ZHANG Xigui MA Liping XIA Baojia | 2006 | Science China(Technological Sciences)2006，49，3： | 3 |
| 7 | Conversion of D-glucose to L-lactate via pyruvate by an optimized cell-free enzymatic biosystem containing minimized reactions显示文摘Cell-free synthetic enzymatic biosystem is emerging to expand the traditional biotechnological mode by utilizing a number of purified/partially purified enzymes and coenzymes in a single reaction vessel for the production of desired products from low-cost substrates.Here,a cell-free synthetic biosystem containing minimized number of reactions was designed for the conversion of D-glucose to L-lactate via pyruvate.This NADH-balanced biosystem was comprised of only 5 thermophilic enzymes without ATP supplementation.After optimization of enzyme loading amounts,buffer concentration and cofactor concentration,D-glucose was converted to L-lactate with a product yield of∼90%.Our study has provided an emerging platform with potentials in producing pyruvatederived chemicals,and may promote the development of cell-free synthetic enzymatic biosystems for biomanufacturing. | Leipeng Xie Xinlei Wei Xigui Zhou Dongdong Meng Ruimin Zhou Yi-Heng P.Job Zhang Shuxia Xu Chun You | 2018 | Synthetic and Systems Biotechnology2018，3，3： | 3 |
| 8 | Late Quaternary Strata and Carbon Burial Records in the Yellow River Delta, China显示文摘Sediment carbon sequestration plays an essential role in mitigating atmospheric CO2 increases and the subsequently global greenhouse effect. To clarify the late Quaternary strata and carbon burial records in Yellow River delta(YRD), detailed analysis of benthic foraminifera, total carbon(TC), organic carbon(Corg), sedimentary characteristics and moisture contents of sediments, was performed on core ZK3, 30.3 m in length and obtained from YRD in 2007. Eight depositional units(designated U1-U8 in ascending order) were identified. A comprehensive analysis method of historical geography and sedimentary geology was used to determine the precise depositional ages of the modern Yellow River delta(MYRD), from which pre-MYRD ages were deduced. The results indicates that the maximum burial rates of TC, inorganic carbon(IC) and Corg occurred in the delta front(U5), and the minimum in the shallow sea(U3). Remarkable high sedimentation rates in the MYRD are responsible for burial efficiency of carbon, with an average rate of Corg burial reaching 2087±251 g(m2 yr)-1, and that of IC reaching 13741±808 g(m2 yr)-1, which are much higher than those of other regions with high contents of Corg. Therefore, YRD has a significant burial efficiency for carbon sequestration. | ZHAO Guangming YE Siyuan LI Guangxue DING Xigui YUAN Hongming | 2015 | Journal of Ocean University of China2015，14，3： | 3 |
| 9 | Geographic variations in the prevalence, awareness, treatment and control of hypertension in China显示文摘 | Kristi Reynolds Dongfeng Gu Paul Muntner Xigui Wu Jing Chen Guanyong Huang Xiufang Duan Paul K Whelton Jiang He | 2003 | Journal of Hypertension2003，，7： | 2 |
| 10 | Prevalence of the metabolic syndrome and overweight among adults in China显示文摘 | Dongfeng Gu Kristi Reynolds Xigui Wu Jing Chen Xiufang Duan Robert F Reynolds Paul K Whelton Jiang He | 2005 | The Lancet . 2005 (9468)2005，，9468： | 2 |
| 11 | Fabrication of ceramic layer on an Al-Si alloy by MAO process显示文摘The MAO (Micro-Arc Oxidation) process is applied to a eutectic Al-Si alloy (Al-12.0%Si-l.0%Cu-0.9%Mg(mass fraction)). The oxide ceramic layer was fabricated with about 220 μm thickness and 3000 Hv micro-hardness. ByXRD (X-ray diffractometry) and DSC (differential scanning calorimetry) analyses, the oxide layer consists of amorphousAl2O3, which is distinct from the results reported by the other researchers. The SEM photographs of such layer show that thelayer is fixed tightly on the substrate alloy. So this alloy can be used in the high temperature and friction environment after itis treated with such process. | SONG Xigui, BIAN Xiufang, QI Xiaogang, and ZHANG JunyanKey Laboratory of Liquid Structure and Heredity of Materials, Ministry of Education, Shandong University (Southern Campus), Jinan 250061, China (Received 2002-04-11) | 2003 | Rare Metals2003，22，2： | 2 |
| 12 | Major causes of death among men and women in China显示文摘 | Jiang He Dongfeng Gu Xigui Wu | 2005 | N EnglJ Med2005，353，11： | 1 |
| 13 | Major causes of death among men and women in China显示文摘 | Jiang He Dongfeng Gu Xigui Wu | 2005 | N Engl J Med2005，353，11： | 1 |
| 14 | Uncata- lyzed ring-opening crosslinking reaction of a fully aromatic poly (ether ketone) hearing macrocyclic cauda显示文摘 | Yue Xigui Wei Wei Zhang Haibo | 2011 | Journal of Macromolecular Science Part a-Pure and Applied Chemistry2011，48，4： | 1 |
| 15 | Prevalence of the metabolic syndrome and overweight among adults in China显示文摘 | GU Dongfeng Reynolds K WU Xigui | | 0，，： | 1 |
| 16 | Major Causes of Death among Men and Women in China显示文摘 | Jiang He Dongfeng Gu Xigui Wu Whelton | 2005 | N Engl J Med2005，353，： | 1 |
| 17 | Major causes of death among men and women in China显示文摘 | Jiang He Dongfeng Gu Xigui Wu | 2005 | N Engl J Med2005，353，： | 1 |
| 18 | Major causes of death among men and women in China显示文摘 | He Jiang Gu Dongfeng Wu Xigui | 2005 | N Engl J Med2005，353，： | 1 |
| 19 | On existence of 2π-periodic solutions for delay Duffing eqution x'+g(t,x(t-(t)))= p(t)显示文摘 | | 1994 | Chinese Science Bulletin1994，，39： | 1 |
| 20 | Major causes of death among men and women in china显示文摘 | Jiang he Dongfeng Gu Xigui W u | 2005 | N Engl J Med2005，353，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员