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| 1 | Small sphincterotomy combined with papillary dilation with large balloon permits retrieval of large stones without mechanical lithotripsy显示文摘瞄准:介绍一个新方法:小内视镜的括约肌切开术(ES ) 与内视镜的乳突的大汽球膨胀(SES + EPLBD ) 结合了与大胆汁的石头对待病人。方法:大胆汁的石头的检索在 88 个病人被执行。吝啬的石头尺寸是 3 公里和石头的吝啬的数字是的 14 +/- 2.5 +/- 3.5。第一,有一个小切口的 ES 被执行。下次,内视镜的乳突的膨胀与一个大汽球被执行慢慢地匹配胆汁管的尺寸。石头然后与一个汽球和一个篮子从胆汁的管被检索。结果:没有需要,石头检索在除了一个膀胱的管石头盒子的所有情况中是成功的压碎大石头。吝啬的过程时间是 30 +/- 5 min。与一个大汽球扩大乳突的孔使没有压碎他们,顺利移开大石头可能。在有大汽球的膨胀以后,有流着,而是没有穿孔的一些例子。procedural 以后胰腺炎(1%) 的一个例子发生了。结论:没有机械碎石术的使用, SES + EPLBD 为大胆汁的石头的检索是有效的。 | Atsushi Minami Shinji Hirose Tomohiro Nomoto Shoichiro Hayakawa | 2007 | World Journal of Gastroenterology2007，13，15： | 24 |
| 2 | DISTRIBUTION AND CHARACTERIZATION OF POLYCYCLIC AROMATIC HYDROCARBON COMPOUNDS IN AIRBORNE PARTICULATES OF EAST ASIA显示文摘A review is presented on the distribution and characterization of polycyclic aromatic hydrocarbons (PAHs) and their derivatives, including nitro-PAHs and hydro-PAHs, on atmospheric particulates of East Asia. Generally, PAH compounds with two or three aromatic rings are released mainly into the gas phase, while those containing three or more aromatic rings are associated with particulate matter (PM) emission. Particle-associated PAHs are primarily adsorbed on fine particles, and little associated with coarse particles. Investigation into the concentration level of PAHs in different areas can serve not only to reflect the pollutant status and sources but also to lead to the formulation of control strategies. The results of the present study show that China has more severe PAH pollution than such East Asian countries as Ja-pan and Korea. | Yan Liu Libin Liu Jin-Ming Lin Ning Tang Kazuichi Hayakawa | 2006 | China Particuology2006，4，6： | 14 |
| 3 | Development of analytical methods for polycyclic aromatic hydrocarbons (PAHs) in airborne particulates: A review显示文摘在现在的工作,不同样品收集,为多不的芳香的烃的预告的处理 andanalytical 方法(哼) 在里面 issystematacially 考察的在空中的微粒,和预告的处理和在 detail.Some 比较的分析方法 forPAHsare 在未来期望上评价的这些的应用也被介绍。 | LIU Li-bin LIU Yan LIN Jin-ming TANG Ning HAYAKAWA Kazuichi MAEDA Tsuneaki | 2007 | Journal of Environmental Sciences2007，19，1： | 10 |
| 4 | Aggressive preoperative management and extended surgery for hilar cholangiocarcinoma: Nagoya experience显示文摘 | Yuji Nimura Junichi Kamiya Satoshi Kondo Masato Nagino Katsuhiko Uesaka Koji Oda Tsuyoshi Sano Hideo Yamamoto Naokazu Hayakawa | 2000 | Journal of Hepato - Biliary - Pancreatic Surgery2000，，2： | 6 |
| 5 | Risk factors for perforation during endoscopic retrograde cholangiopancreatography in post-reconstruction intestinal tract显示文摘BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP) in patients with surgically altered anatomy has been a major challenge to gastrointestinal endoscopists with low success rates for reaching the target site as well as high complication rates. The knowledge of ERCP-related risk factors is important for reducing unexpected complications.AIM To identify ERCP-related risk factors for perforation in patients with surgically altered anatomy.METHODS The medical records of 187 patients with surgically altered anatomy who underwent ERCP at our institution between April 2009 and December 2017 were retrospectively reviewed. An analysis of patient data, including age, sex, type of reconstruction, cause of surgery, aim of ERCP, success rate of reaching target site,success rate of procedure, adverse events, type of scope, time to reach the target site, and duration of procedure, was performed. In patients with Billroth-Ⅱ reconstruction, additional potential risk factors were the shape of the inserted scope and whether the anastomosis was antecolic or retrocolic.RESULTS All patients(n = 187) had surgical anatomy, such as Billroth-Ⅰ(n = 22), Billroth-Ⅱ(n = 33), Roux-en-Y(n = 54), Child, or Whipple reconstruction(n = 75). ERCP was performed for biliary drainage in 43 cases(23%), stone removal in 29 cases(16%),and stricture dilation of anastomosis in 59 cases(32%). The scope was unable to reach the target site in 17 cases(9%), and an aimed procedure could not be accomplished in 54 cases(29%). Adverse events were pancreatitis(3%),hyperamylasemia(10%), cholangitis(6%), cholestasis(4%), excessive sedation(1%), perforation(2%), and others(3%). Perforation occurred in three cases, all of which were in patients with Billroth-Ⅱ reconstruction; in these patients, further analysis revealed loop-shaped insertion of the scope to be a significant risk for perforation(P = 0.01).CONCLUSION Risk factors for perforation during ERCP in patients with surgically altered anatomy were Billroth-Ⅱ reconstruction and looping of the scope during BillrothⅡ procedure. | Shinichi Takano Mitsuharu Fukasawa Hiroko Shindo Ei Takahashi Sumio Hirose Yoshimitsu Fukasawa Satoshi Kawakami Hiroshi Hayakawa Hiroshi Yokomichi Makoto Kadokura Tadashi Sato Nobuyuki Enomoto | 2019 | World Journal of Clinical Cases2019，7，1： | 6 |
| 6 | The ultra-low-frequency magnetic disturbances associated with earthquakes显示文摘The ultra-low-frequency(ULF) electromagnetic emission is recently recognized as one of the most promising candidates for short-term earthquake(EQ) prediction.This paper reviews previous convincing evidence on the presence of ULF emissions before three major EQs.Then,we present further statistical study on the ULF occurrence,our networks of ULF monitoring in different spatial scales in Japan and finally we present several signal processings to identify the seismogenic emissions by showing latest results for recent large EQs. | Masashi Hayakawa Yasuhide Hobara Kenji Ohta Katsumi Hattori | 2011 | Earthquake Science2011，24，6： | 5 |
| 7 | Probing the lower ionospheric perturbations associated with earthquakes by means of subionospheric VLF/LF propagation显示文摘There have been reports for many years that the ionosphere is very sensitive to seismic effects, and the detection of ionospheric perturbations associated with earthquakes(EQs) attracts a lot of attention as a very promising candidate for short-term EQ prediction.In this review we present a possible use of VLF/LF (very low frequency(3-30 kHz)/low frequency(30-300 kHz)) radio sounding of seismo-ionospheric perturbations. In order to avoid the overlapping with my own previous reviews,we first show some pioneering results for the Kobe EQ and we try to present the latest results including the statistical evidence on the correlation between the VLF/LF propagation anomalies(ionospheric perturbations) and EQs(especially with large magnitude and with shallow depth),medium-distance(6-8 Mm) propagation anomalies,the fluctuation spectra of subionospheric VLF/LF data(the effect of atmospheric gravity waves,the effect of Earth’s tides,etc.),and the mechanism of lithosphere-atmosphere-ionosphere coupling.Finally,we indicate the present situation of this kind of VLF/LF activities going on in different parts of the globe and we suggest the importance of international collaboration in this seismo-electromagnetic study. | Masashi Hayakawa | 2011 | Earthquake Science2011，24，6： | 5 |
| 8 | 日本香川地区荷斯坦牛乳与娟姗牛乳营养成分的比较显示文摘目的比较日本香川地区荷斯坦和娟姗牛乳中乳清蛋白的总蛋白质含量,乳过氧化物酶(LPO)和乳铁蛋白的一些基本性质。方法以荷斯坦和娟姗牛乳为对象,经酸沉淀除酪蛋白后,通过离心,SP-Sepharose离子交换层析分离纯化得到乳过氧化物酶和乳铁蛋白,利用考马斯亮蓝定量、SDS-PAGE定性、ABTS检测乳过氧化物酶活性、最后通过基质辅助激光解吸电离飞行时间质谱(MALDI-TOF-MS)确认分子量。结果娟姗牛乳中乳清蛋白的总蛋白质和乳过氧化物酶含量均高于荷斯坦中乳清蛋白中的总蛋白质和乳过氧化物酶含量。娟姗乳清蛋白中的乳过氧化物酶活性(0.870 5 U/ml)高于荷斯坦乳清蛋白中的乳过氧化物酶活性(0.758 9 U/ml)。娟姗乳清蛋白中的乳过氧化物酶和乳铁蛋白分子量分别为786 48.154和831 23.538 k Da,荷斯坦乳清蛋白中的乳过氧化物酶和乳铁蛋白分子量分别为777 64.841和827 65.494 k Da。结论对于乳酪行业,当考虑养殖奶牛品种生产乳酪同时又想最大限度利用需要处理的乳清蛋白和乳铁蛋白的时候,相比于荷斯坦奶牛,娟姗奶牛是更好的选择。 | 王任 Shigeru Hayakawa 周明昊 罗金文 | 2015 | 中国食品卫生杂志2015，27，6： | 4 |
| 9 | Distal pancreatectomy withen bloc resection of the celiac artery for carcinoma of the body and tail of the pancreas显示文摘 | Toshihiko Mayumi Yuji Nimura Junichi Kamiya Satoshi Kondo Masato Nagino Michio Kanai Masahiko Miyachi Katsura Hamaguchi Naokazu Hayakawa | 1997 | International Journal of Gastrointestinal Cancer1997，，1： | 4 |
| 10 | 超低频地磁异常与2000年日本伊豆诸岛震群的关系显示文摘通过研究电磁现象与大地震的联系有助于建立监测地壳运动(如地震、火山喷发)的电磁方法.在地震的紧急预报中,超低频(ULF)地磁的方法是最有前途的方法之一.本文将一种主要分量分析的新方法应用在了与2000年日本伊豆诸岛震群有关的ULF地磁资料的研究中.这次震群活动始于2000年6月26日,同年9月结束.在这次地震活动中,观测到5次震级超过6级的大地震(分别发生在7月1日、8日、15日、30日和8月18日).在此期间,我们的超低频地磁观测站幸运地记录下了数据,其中有三个观测站相距很近(大约5 km的距离),距地震中心大约80~100 km.因为我们可以在正交分解的基础上,用主要分量分析法将一些噪声分辨出来,所以我们把主要分量分析法用在了超低频地磁水平方向的NS分量中.我们研究了主要分量分析法结果中本征值和本征矢量的临时变化,这些结果总结如下.第一主要分量是源于日地交互作用影响的信号,如:地磁脉动.第一主要分量的本征矢量的变化说明这种信号在整个分析过程中非常稳定.第二主要分量中混有当地的人为的噪音.而最小的第三分量出现在伊豆半岛当地的子夜,在大地震前几天,第三本征值明显地增加.大约在震群活动开始前三个月,第三本征值的水平有微小增强.相应地,在信号的子空间中本征矢量方向的模式同时改变,在震群活动后又恢复到了其原来的水平.这些特征可能与大地震有关.最后我们强调主要分量分析的方法是目前监测地壳活动最有前途的方法. | Katsumi Hattori Aya Serita Kaoru Gotoh Chie Yoshino Makoto Harada Nobuhiro Isezaki Masashi Hayakawa 辛长江 | 2005 | 国际地震动态2005，，11： | 4 |
| 11 | Influence of Agricultural Activity on Nitrogen Budget in Chinese and Japanese Watersheds显示文摘To analyze the effect of agricultural activity on nitrogen(N) budget at the watershed scale,a comparative study was conducted at two Japanese watersheds,the Shibetsu River watershed(SRW) and Upper-Naka River watershed(UNRW),and one Chinese watershed,the Jurong Reservoir watershed(JRW).The total area and the proportion of agricultural area(in parentheses) of the watersheds were 685(51%),1 299(21%),and 46 km 2(55%) for SRW,UNRW,and JRW,respectively.The main agricultural land use in SRW was forage grassland,while paddy fields occupied the highest proportion of cropland in UNRW(11% of total area) and JRW(31% of total area).The farmland surplus N was 61,48,and 205 kg N ha 1 year 1 for SRW,UNRW,and JRW,respectively.The total input and output for the whole watershed were 89 and 76,83 and 61,and 353 and 176 kg N ha 1 year 1 for SRW,UNRW,and JRW,respectively.The proportion of discharged N to net anthropogenic N input was 31%,37%,and 1.7% for SRW,UNRW,and JRW,respectively.The two watersheds in Japan showed similar proportions of discharged N to those of previous reports,while the watershed in China(JRW) showed a totally different characteristic compared to previous studies.The high N input in JRW did not increase the amount of discharged N at the outlet of the watershed due to high proportions of paddy fields and water bodies,which was an underestimated N sink at the landscape scale. | S. D. KIMURA YAN Xiao-Yuan R. HATANO A. HAYAKAWA K. KOHYAMA TI Chao-Pu DENG Mei-Hua M. HOJITO S. ITAHASHI K. KURAMOCHI CAI Zu-Cong M. SAITO | 2012 | Pedosphere2012，22，2： | 4 |
| 12 | STUDY ON SIMILARITY LAWS OF A DISTORTED RIVER MODEL WITH A MOVABLE BED显示文摘WT5”BZ]In this study, by considering the scale ratio related to the specific gravity of the submerged bed material, and introducing a degree of distortion, n the similarity laws for a distorted river model with a movable bed were derived under the conditions that the values of dual dimensionless parameters in a regime-criterion diagram for the bars are the same in a model as they are in a prototype, and that a resistance law such as the Manning-Strickler-type formula is to be valid for a model and a prototype. The usefulness of the similarity laws derived in this study was verified by comparing the bed forms from the distroted model experiments with the bed forms from the 1/50-scale undistorted model experiments, which were performed by the Hokkaido Development Bureau (H. D. B.), Japan, to examine the tentative plan for the improvement of a low-flow channel in the Chubetsu River, which is a tributary of the Ishikari River. It is considered that the distorted model experiments to be valid with either sand or lightweight bed material. [WT5”HZ] | Wei Bing-qian, Kunihide Uchijima, Hiroshi Hayakawa Department of Civil Engineering, Kitami Institude of Technology, 165, Koen-cho, Kitami, Hokkaido 090-8507, Japan | 2001 | Journal of Hydrodynamics2001，13，1： | 3 |
| 13 | Hepatic segmentectomy with caudate lobe resection for bile duct carcinoma of the hepatic hilus显示文摘 | Yuji Nimura M.D. Naokazu Hayakawa M.D. Junichi Kamiya M.D. Satoshi Kondo M.D. Shigehiko Shionoya M.D | 1990 | World Journal of Surgery1990，，4： | 2 |
| 14 | Progastrin Stimulates Colonic Cell Proliferation via CCKBR- and β-Arrestin–Dependent Suppression of BMP2显示文摘 | Guangchun Jin C. Benedikt Westphalen Yoku Hayakawa Daniel L. Worthley Samuel Asfaha Xiangdong Yang Xiaowei Chen Yiling Si Hongshan Wang Yagnesh Tailor Richard A. Friedman Timothy C. Wang | 2013 | Gastroenterology2013，，： | 2 |
| 15 | Differences in the time course of splenial and white matter lesions in clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS)显示文摘 | Jun-ichi Takanashi Atsushi Imamura Fumio Hayakawa Hitoshi Terada | 2010 | Journal of the Neurological Sciences2010，，1： | 2 |
| 16 | 2-14 Investigation of the Thermonuclear 18Ne(α, p)21Na Reaction Rate via Resonant Elastic Scattering of 21Na + p显示文摘A nuclear astrophysics experiment was performed at CRIB (CNS low-energy Radioactive-Ion Beam separator)on Mar. 2011. The goal of this experiment is to study the reaction rate of 18Ne(,p)21Na reaction, which mightbe a key breakout reaction from the hot CNO cycle to rp-process in X-ray burst and nova. Yet its reaction rate ispoorly known.Explosive hydrogen burning is thought to be the main source of energy generation and a source of nucleosynthesisin X-ray burst and nova[1;2]. For example, XRBs are characterized by a sudden increase of X-ray emission withinonly a few seconds to a total energy output of about 1040 ergs, which is observed to repeat with some regularity.The recurrence time for single bursts can range from hours to days at the typical temperature of 0.4~2 GK. Thebursts have been interpreted as being generated by thermonuclear runaway on the surface of a neutron star thataccretes H- and He-rich material from a less evolved companion star in a close binary system. As shown in Fig. 1,under its typical temperature, the hydrogen burning in X-ray burst occurs from the hot CNO cycle: | Zhang Liyong He Jianjun Xu Shiwei H.Yamaguchi S. Kubono Y.Wakabayashi Chen Size Hu Jun Ma Peng Y. Togano T. Hashimoto D. Kahl T. Teranishi Chen Ruofu Wang Hongwei Tian Wendong Guo Bing S. Hayakawa N. Iwasa T. Yamada T. Komatsubara | 2014 | IMP & HIRFL Annual Report2014，，1： | 2 |
| 17 | On-chip 3D rotation of oocyte based on a vibration-induced local whirling flow显示文摘We propose a novel on-chip 3D cell rotation method based on a vibration-induced flow.When circular vibration is applied to a microchip with micropillar patterns,a highly localized whirling flow is induced around the micropillars.The direction and velocity of this flow can be controlled by changing the direction and amplitude of the applied vibration.Furthermore,this flow can be induced on an open chip structure.In this study,we adopted a microchip with three micropillars arranged in a triangular configuration and an xyz piezoelectric actuator to apply the circular vibration.At the centre of the micropillars,the interference of the vibration-induced flows originating from the individual micropillars induces rotational flow.Consequently,a biological cell placed at this centre rotates under the influence of the flow.Under three-plane circular vibrations in the xy,xz or yz plane,the cell can rotate in both the focal and vertical planes of the microscope.Applying this 3D cell rotation method,we measured the rotational speeds of mouse oocytes in the focal and vertical planes as 63.7±4.0°s^(−1) and 3.5±2.1°s^(−1),respectively.Furthermore,we demonstrated the transportation and rotation of the mouse oocytes and re-positioned their nuclei into a position observable by microscope. | Takeshi Hayakawa Shinya Sakuma Fumihito Arai | 2015 | Microsystems & Nanoengineering2015，1，1： | 2 |
| 18 | Examining the properties and therapeutic potential of glial restricted precursors in spinal cord injury显示文摘In the aftermath of spinal cord injury,glial restricted precursors(GRPs) and immature astrocytes offer the potential to modulate the inflammatory environment of the injured spinal cord and promote host axon regeneration.Nevertheless clinical application of cellular therapy for the repair of spinal cord injury requires strict quality-assured protocols for large-scale production and preservation that necessitates long-term in vitro expansion.Importantly,such processes have the potential to alter the phenotypic and functional properties and thus therapeutic potential of these cells.Furthermore,clinical use of cellular therapies may be limited by the inflammatory microenvironment of the injured spinal cord,altering the phenotypic and functional properties of grafted cells.This report simulates the process of large-scale GRP production and demonstrates the permissive properties of GRP following long-term in vitro culture.Furthermore,we defined the phenotypic and functional properties of GRP in the presence of inflammatory factors,and call attention to the importance of the microenvironment of grafted cells,underscoring the importance of modulating the environment of the injured spinal cord. | Kazuo Hayakawa Christopher Haas Itzhak Fischer | 2016 | Neural Regeneration Research2016，11，4： | 2 |
| 19 | Systemic Inflammation and Disseminated Intravascular Coagulation in Early Stage of ALI and ARDS: Role of Neutrophil and Endothelial Activation显示文摘 | Satoshi Gando Takashi Kameue Naoyuki Matsuda Atsushi Sawamura Mineji Hayakawa Hirokatsu Kato | 2004 | Inflammation2004，，4： | 2 |
| 20 | Decomposition of Polycyclic Aromatic Hydrocarbon (PAHs) on Mineral Surface under Controlled Relative Humidity显示文摘多不的芳香的烃的命运(哼) 居住在空气在最近的年里收到了庞大的注意由于他们的诱变并且人的健康上的 carcinogenicrisks。在这上下文,分核的稳定性(当一个代表哼) 在石英,氧化铝,胶岭石,高岭石,腐殖酸和与 sorbed 涂的石英上,腐殖酸在控制相对湿度被调查(RH:即 5% 和 30%) 没有轻照耀以便在 PAHsdecomposition 上检测矿物质表面的催化效果的存在。分核的稳定性被发现强烈取决于底层的物理化学性质。尽管它与 sorbed 腐殖酸是涂的,石英为分核的分解显示出强壮的催化效果。蒙脱石和腐殖酸上的分核 sorbed 在试验性的时期期间仍然保持稳定(即 3 天) 。在试验性的房间的潮湿也特别地影响了分核的稳定性矿物质。特别,氧化铝上的分核 sorbed 很快在更高的 RH 被分解。然而,有几乎不在石英,高岭石和腐殖酸的情况中完成。取决于喷雾器和 RH 的物理化学性质,有在空气的矿物质的 PAHsassociated 将被分解或稳定地居住在空气。 | Shuji TAMAMURA Tsutomu SATO Yukie OTA Ning TANG Kazuichi HAYAKAWA | 2006 | Acta Geologica Sinica(English Edition)2006，80，2： | 2 |
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