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| 1 | 中国的噪声性听力损害是一个潜在严重的公众健康问题显示文摘听力损失和耳鸣是长期噪声暴露的最常见的后果,它是大多数发展中国家将面临的严重健康问题。快速的工业化进程与人们生活方式的改变使得我国对噪声暴露和噪声诱发听力损失(NIHL)越来越关注。然而我国对NI-HL的研究仍然有限。本文回顾了我国噪声暴露及NIHL的研究,讨论了其对我国人口的影响,以及Dangerous Deci-bels?等研究模型在我国有效应用的可能性,以呼吁加强对我国公民(特别是年轻人)关于NIHL及其预防措施的科普教育工作,并提出语言文化对国际信息传播和行为干预方面的影响。 | 石勇兵 William Hal Martin 隋音 张晶平 | 2016 | 中华耳科学杂志2016，14，6： | 30 |
| 2 | Nature:骨髓微环境发生突变可导致造血干细胞异常显示文摘白血病骨髓微环境中支持血液发育的某些DNA突变可以驱动周围造血干细胞形成白血病,来自艾默里大学温希普癌症研究所和亚特兰大儿童健康中心的研究人员在国际学术期刊Nature上公布了他们的最新研究进展。许多致癌突变都作用于细胞自身。让细胞自身生长更快。相比之下,努南综合征小鼠模型上可以观察到间接的邻近细胞效应,努南综合征是一种能够增加白血病患病风险的遗传紊乱。 | Lei Dong, Wen-Mei Yu, Hong Zheng, Melinda Pauly, Muxiang Zhou Cheng-Kui Qu Mignon L. Loh Silvia T. Bunting Gang Huang Hal E. Broxmeyer David T. Scadden | 2016 | 现代生物医学进展2016，16，35： | 18 |
| 3 | 不断发展的触摸屏技术显示文摘我们可能都有过这样的经历:为了使触摸屏能捕获到输入,我们一而再再而三地点击触摸屏,且一次比一次加大力气。早期的电阻式触摸屏技术有很多不足,如易受各种机械磨损的影响,以及在某些环境下性能不稳定等。而现在这一切都改变了。 | Hal Philipp | 2008 | 世界电子元器件2008，，4： | 13 |
| 4 | 澳大利亚的健康老龄化:政策响应和研究机遇显示文摘 | Colette Browning Hal Kendig Shane Thomas 杨辉 | 2006 | 中国全科医学2006，9，19： | 11 |
| 5 | mi R-122 negatively correlates with liver fibrosis as detected by histology and FibroScan显示文摘AIM: To investigate whether expression of selected mi RNAs obtained from fibrotic liver biopsies correlate with fibrosis stage.METHODS: Altogether, 52 patients were enrolled in the study representing various etiologic backgrounds of fibrosis: 24 cases with chronic hepatitis infections(types B, C), 19 with autoimmune liver diseases(autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, overlapping syndrome cases), and 9 of mixed etiology(alcoholic and nonalcoholic steatosis, cryptogenic cases). Severity of fibrosis was determined by both histologic staging using the METAVIR scoring system and noninvasive transient elastography. Following RNAisolation, expression levels of mi R-21, mi R-122, mi R-214, mi R-221, mi R-222, and mi R-224 were determined using Taq Man Micro RNA Assays applying mi R-140 as the reference. Selection of mi RNAs was based on their characteristic up- or downregulation observed in hepatocellular carcinoma. Relative expression of mi RNAs was correlated with fibrosis stage and liver stiffness(LS) value measured by transient elastography, as well as with serum alanine aminotransferase(ALT) level.RESULTS: The expression of individual mi RNAs showed deregulated patterns in stages F1-F4 as compared with stage F0, but only the reduced level of mi R-122 in stage F4 was statistically significant(P < 0.04). When analyzing mi RNA expression in relation to fibrosis, levels of mi R-122 and mi R-221 showed negative correlations with fibrosis stage, and mi R-122 was found to correlate negatively and mi R-224 positively with LS values(all P < 0.05). ALT levels displayed a positive correlation with mi R-21(P < 0.04). Negative correlations were observed in the fibrosis samples of mixed etiology between mi R-122 and fibrosis stage and LS values(P < 0.05), and in the samples of chronic viral hepatitis, between mi R-221 and fibrosis stage(P < 0.01), whereas mi R-21 showed positive correlation with ALT values in the samples of autoimmune liver diseases(P < 0.03). The results also revealed a strong correlation between fibrosis stage and LS values(P < 0.01) when etiology of fibrosis was not taken into account.CONCLUSION: Reduced expression of mi R-122 in advanced fibrosis and its correlation with fibrosis stage and LS values seem to be characteristic of hepatic fibrosis of various etiologies. | Tünde Halász Gábor Horváth Gabriella Pár Klára Werling András Kiss Zsuzsa Schaff Gábor Lendvai | 2015 | World Journal of Gastroenterology2015，21，25： | 11 |
| 6 | A new iridoid glycoside from Gardenia jasminoides显示文摘新 iridoid glycoside, 6 ′ - O-sinapoylgeniposide,从栀子 jasminoides 埃利斯被孤立,它的结构根据 1D 和 2D NMR 被阐明, HR-ESI-MS 技术。 | Xiao Qin Zhou Zhi Ming Bi Ping Li Dan Tang Hal Xia Cai | 2007 | Chinese Chemical Letters2007，18，10： | 10 |
| 7 | Frequency of infarct-related artery with myocardial bridging in patients with ST-elevation myocardial infarction and its impact upon percutaneous coronary intervention显示文摘Background Myocardial bridging (MB) as a congenital condition with a reported frequency of 5%-12% in diagnostic coronary angiography may be an important factor causing myocardial ischemia. However, its frequency in the infarct-related artery (IRA) of patients with ST-elevation myocardial infarction (STEMI) and the impact upon percutaneous coronary intervention (PCI) remain undetermined. In this study, we investigated MB frequency and its impact upon primary PCI in patients with STEMI. Methods The data of coronary angiography for 554 consecutive patients with STEMI who had undergone successful primary PCI were retrospectively analyzed to identify a frequency of MB in the IRA and its association with gender and age. According to the angiographic findings, the patients were divided into MB patients and non-MB patients. The endpoints of this study included immediate angiographic findings after primary PCI and 6-month major adverse cardiac events (MACE) (death, recurrent myocardial infarction, target lesion or vessel revascularization) between the MB patients and the non-MB patients. Results A frequency of MB in the IRA of 46 patients (8.3%) was identified in this series; it was more common in patients ≥65 years old (36/206) than in those <65 years old (10/348) (17.5% vs 2.9%, P<0.001). The trend of MB in the IRA was observed more frequently in women without significant difference than in men (10.2% vs 7.8%). TIMI grade III flow was achieved in 91.9% (509/554) of all patients following primary PCI, in 60.9% (28/46) of the MB patients and in 94.7% (481/508) of the non-MB patients respectively (P<0.001). The in-hospital mortality was 4.7% (26/554) in this series including 13.0% (6/46) of the MB patients and 3.9% (20/508) of the non-MB patients (P<0.001). A significant difference in 6 months MACE was seen between the MB patients (19%) and the non-MB patients (6.2%) (P<0.001). Conclusions MB in the IRA is relatively common in elderly patients with STEMI with a more evident trend in women, suggesting that arteriosclerosis and plaque rupture occurs more easily in the proximal artery to MB than in younger patients. Poor TIMI grade flow in patients with MB in the IRA after primary PCI may contribute to a high in-hospital mortality rate (13%) and 6-month MACE (19%) in the MB patients. | YAN Hong-bing WANG Jian ZHU Xiao-ling GAO Hal LI Nan AI Hui | 2006 | Chinese Medical Journal2006，，7： | 9 |
| 8 | 资源型城市财源建设的风险识别与制度优化路径--以陕西省延安市为例显示文摘1994年财税体制改革促成了此后延续至今的改革红利,但其财政分权的改革远未到位,近年来能源富集区经济发展中遇到的地方税收体系建设滞后、地方政府财政困难、提供基本公共服务能力弱等问题均与此密切相关。今后所实施新一轮改革中,财税体制改革是全面深化经济体制改革的核心之一,应重点解决资源富集区矿产资源开发收益没有得到合理分配对地方政府财源建设所带来的风险。本文以陕西省延安市为例,认真分析财源结构、三次产业税收收入、税收收入与非税收收入的状况,以及省市分税的影响,深入研究现行财政分权影响地方财源建设的四大风险:税收与税源分离的风险、三次产业税源结构调整的风险、财政收支缺口的风险和税制改革滞后所引发的潜在风险,并深入剖析问题根源,积极探索优化资源型城市财源建设的制度路径。 | 宋敏 刘学敏 Hal T.Nelson | 2016 | 中国软科学2016，，10： | 7 |
| 9 | 触摸屏设计日益简化 投射式电容触摸屏前景广阔显示文摘现今社会上很多人都频繁地接触到触摸屏。这种装置最常见于PDA和手机等手持设备和售票终端系统等应用,其中大部分都基于电阻性技术。电阻性技术采用一个柔性外层,其压触固定内层时,会产生电信号,然后转换为x—Y坐标位置。此外,还有其它两种常用技术:表面声波(SAW)和电容感测技术,不过,一直以来,由于成本和构建的限制,这两种技术都仅用在公用信息服务应用(Kioskapplications)中。 | Hal Philipp | 2009 | 中国电子商情2009，，9： | 5 |
| 10 | A Novel Sesquiterpenoid from Glechoma longituba显示文摘A novel sesquiterpenoid was isolated from the whole plant of Glechoma longituba. Its structure was elucidated as 1, 8-epoxy-7(11)-germacren-5-one-12, 8-olide 1 on the basis of spectral evidences. | Qian Jun ZHANG Xiao Sheng YANG Hal Yan ZHU Ye WANG Xiao Jiang HAO Bao An SONG | 2006 | Chinese Chemical Letters2006，17，3： | 5 |
| 11 | Deep Brain Stimulation──A new treatment for tinnitus显示文摘Intractable tinnitus can lead to serious consequences. Study evidence indicates that the central nervous system is involved in generation and maintenance of chronic tinnitus and that tinnitus and other neurologic symptoms such as chronic pain may share similar mechanisms. Brain ablation and stimulation are used to treat chronic pain with success. Recent studies showed that ablation and stimulation in non-auditory areas resulted in tinnitus improvement. Deep brain stimulation (DBS) may be an alternative treatment for intractable tinnitus and deserves further study. | William Hal Martin | 2007 | Journal of Otology2007，2，1： | 4 |
| 12 | Full scale experimental study of a small natural draft dry cooling tower for concentrating solar thermal power plant显示文摘Concentrating solar thermal power system can provide low carbon,renewable energy resources in countries or regions with strong solar irradiation.For this kind of power plant which is likely to be located in the arid area,natural draft dry cooling tower is a promising choice.To develop the experimental studies on small cooling tower,a 20 m high natural draft dry cooling tower with fully instrumented measurement system was established by the Queensland Geothermal Energy Centre of Excellence.The performance of this cooling tower was measured with the constant heat input of 600 kW and 840 kW and with ambient temperature ranging from 20 ℃ to 32 ℃.The cooling tower numerical model was refined and validated with the experimental data.The model of 1 MW concentrating solar thermal supercritical CO2 power cycle was developed and integrated with the cooling tower model.The influences of changing ambient temperature and the performance of the cooling tower on efficiency of the power system were simulated.The differences of the mechanism of the ambient temperature effect on Rankine cycle and supercritical CO2 Brayton cycle were analysed and discussed. | Xiaoxiao Li Sam Duniam Hal Gurgenci Zhiqiang Guan Anand Veeraragavan 侯恩哲 | 2017 | 建筑节能2017，45，5： | 4 |
| 13 | Recommender systems显示文摘 | Paul Resnick Hal R. Varian | 1997 | Communications of the ACM1997，，3： | 4 |
| 14 | RANKL/RANK control Brca1 mutation-driven mammary tumors显示文摘 | Verena Sig Kwadwo Owusu-Boaitey Puma A Joshi Anoop Kavirayani Gerald Wimsberger Maria Novatchkova Ivona Kozieradzki Daniel Schramek Nnamdi Edokobi Jerome Hersl Aishia Sampson Ashley Odai-Afotey Conxi Lazaro Eva Gonzalez-Suarez Miguel A Pujaaa for CIMBA Holger Heyn Enrique Vidal Jennifer Cru. ickshank Hal Berman Renu Sarao Melita Tieevic Iris Uribesalgo Luigi Tortola Shuan Rao Yen Tan Georg Pfeiler Eva YHP Lee Zsuzsanna Bago-Horvath Lukas Kenner Helmuth Popper Christian Singer Rama Khokha LaundeRe P Jones Josef M Penninger | 2016 | Cell Research2016，26，7： | 3 |
| 15 | 温度对碳热还原/氮化法合成氮化硅的影响显示文摘碳热还原/氮化合成Si3N4在1300~1600℃下N2或N2-H2混合气中进行。反应物由非晶SiO2与C粉以1∶4.5摩尔比混合、压片。产生的CO由红外传感器监测,样品中氧、氮、碳含量由LECO元素分析仪测得,混合物各相由X射线衍射(XRD)检测。SiO2还原反应在1300℃以下开始,速率随温度升高增大;温度高于1570℃时,速率因反应物表面被生成物覆盖降低。由于还原产物CO平衡分压差别小,选择生成Si3N4或SiC的临界温度不明显。碳热还原/氮化法合成氮化硅的原理需进一步探讨。 | 万小涵 张广清 Oleg Ostrovski Hal Aral | 2015 | 中国工程科学2015，17，1： | 3 |
| 16 | Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease显示文摘 | Edward M. Kennedy Leda C. Bassit Henrik Mueller Anand V.R. Kornepati Hal P. Bogerd Ting Nie Payel Chatterjee Hassan Javanbakht Raymond F. Schinazi Bryan R. Cullen | 2014 | Virology2014，，： | 3 |
| 17 | 基于切削电流指数新异检测的长壁采煤机监测方法研究显示文摘在定义采煤机切削电流指数的基础上,采用统计分析和支持向量机方法,对采煤机健康状态进行了新异故障检测方法的研究,通过大量正常数据,构建和训练了新异类检测器.通过对澳大利亚某煤矿1号采煤机的实测数据应用表明,该检测器可有效检测意外发生的未知故障.图7,表3,参8. | 秦国军 胡茑庆 官志强 Hal Gurgenci | 2006 | 湖南科技大学学报(自然科学版)2006，21，2： | 2 |
| 18 | Elevated miR-33a and miR-224 in steatotic chronic hepatitis Cliver biopsies显示文摘AIM:To assess the expression of selected microRNAs(miRNA) in hepatitis C,steatotic hepatitis C,noninfected steatotic and normal liver tissues.METHODS:The relative expression levels of miR-21,miR-33 a,miR-96,miR-122,miR-125 b,miR-221 and miR-224 were determined in 76 RNA samples isolated from 18 non-steatotic and 28 steatotic chronic hepatitis C(CHC and CHC-Steatosis,respectively) cases,18 non-infected,steatotic liver biopsies of metabolic origin(Steatosis) and 12 normal formalin-fixed paraffin-embedded liver tissues using TaqMan MicroRNA Assays.All CHC biopsy samples were obtained prior to initiating therapy.Patients' serum biochemical values,which included glucose,triglyceride,cholesterol,alanine aminotransferase(ALT),aspartate aminotransferase(AST),gamma-glutamyl-transferase(GGT),alkaline phosphatase(AP),were obtained and correlated with relative miRNA expression.RESULTS:When compared with control non-infected liver samples,miR-122 and miR-221 levels were reduced in CHC-Steatosis(P < 0.03) and in CHC,CHCSteatosis and Steatosis(P < 0.01).Alternatively,the expression of miR-33 a and miR-224 were elevated in CHC-Steatosis and Steatosis in comparison to control tissue(P < 0.01).The levels of miR-33 a and miR-224 in CHC-Steatosis(P < 0.02) and miR-224 in Steatosis(P < 0.001) were increased in comparison to CHC samples.By contrast,the expression of miR-21 did not differ statistically between diseased and normal liver samples.Levels of miR-33 a correlated negatively with serum AST and AP levels in Steatosis as well as with necroinflammatory grade in CHC,whereas miR-21 correlated positively with AST in Steatosis and displayed negative correlation with triglyceride level in CHC-Steatosis.In contrast,miRNA levels were not correlated with ALT,GGT,cholesterol levels or fibrosis stage.CONCLUSION:Differences in miRNA expression were observed between CHC and steatotic CHC,CHC and steatotic liver,but not between steatotic CHC and steatotic liver of metabolic origin. | Gabor Lendvai Katalin Jármay Gizella Karácsony Tünde Halász Ilona Kovalszky Kornélia Baghy Tibor Wittmann Zsuzsa Schaff András Kiss | 2014 | World Journal of Gastroenterology2014，20，41： | 2 |
| 19 | Predicting the Present with Google Trends显示文摘 | HYUNYOUNG CHOI HAL VARIAN | 2012 | Economic Record2012，，： | 2 |
| 20 | A randomised control trial of a self-management program for people with a chronic illness from Vietnamese, Chinese, Italian and Greek backgrounds显示文摘 | Hal Swerissen John Belfrage Amanda Weeks Lucinda Jordan Christine Walker John Furler Brian McAvoy Meredith Carter Chris Peterson | 2006 | Patient Education and Counseling2006，，1： | 2 |
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