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| 1 | Label-free detection repeatability of protein microarrays by oblique-incidence reflectivity difference method显示文摘We examine the repeatabilities of oblique-incidence reflectivity difference(OIRD) method for label-free detecting biological molecular interaction using protein microarrays.The experimental results show that the repeatabilities are the same in a given microarray or microarray-microarray and are consistent,indicating that OIRD is a promising label-free detection technique for biological microarrays. | DAI Jun LI Lin WANG JingYi HE LiPing LU HuaBin RUAN KangCheng JIN KuiJuan YANG GuoZhen | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，12： | 3 |
| 2 | A risk-prediction score for colorectal lesions on 12,628 participants at high risk of colorectal cancer显示文摘Background The uptake of colonoscopy is low in individuals at risk of colorectal cancer(CRC).We constructed a riskprediction score(RPS)in a large community-based sample at high risk of CRC to enable more accurate risk stratification and to motivate and increase the uptake rate of colonoscopy.Methods A total of 12,628 participants classified as high-risk according to positivity of immunochemical fecal occult blood tests or High-Risk Factor Questionnaire underwent colonoscopy.Logistic regression was used to derive a RPS and analysed the associations of the RPS with colorectal lesions,giving odds ratios(ORs)and 95%confidence intervals(CIs).Results Of the participants,men(OR=1.73,95%CI=1.58–1.90),older age(≥65 years;1.41,1.31–1.53),higher body mass index(≥28 kg/m^(2);1.22,1.07–1.39),ever smoking(1.47,1.31–1.65),and weekly alcohol use(1.28,1.09–1.52)were associated with a higher risk of colorectal lesions.We assigned 1 point to each of the above five risk factors and derived a RPS ranging from 0 to 5,with a higher score indicating a higher risk.Compared with a RPS of 0,a RPS of 1,2,3,and 4–5 showed a higher risk of colorectal lesions,with the OR(95%CI)being 1.50(1.37–1.63),2.34(2.12–2.59),3.58(3.13–4.10),and 3.91(3.00–5.10),respectively.The area under the receiver-operating characteristic curve of RPS in predicting colorectal lesions was 0.62.Conclusions Participants with an increase in the RPS of≥1 point had a significantly higher risk of colorectal lesions,suggesting the urgency for measuring colonoscopy in this very high-risk group.High-risk strategies incorporating RPS may be employed to achieve a higher colonoscopy-uptake rate. | Lixin Liang Yingru Liang Ke Li Pengzhe Qin Guozhen Lin Yan Li Huan Xu Suixiang Wang Qinlong Jing Boheng Liang Lin Xu | 2022 | Gastroenterology Report2022，10，1： | 2 |
| 3 | Orchestrating Network Functions in Software-Defined Networks显示文摘Software.defined networking(SDN) enables third.part companies to participate in the network function innovations. A number of instances for one network function will inevitably co.exist in the network. Although some orchestration architecture has been proposed to chain network functions, rare works are focused on how to optimize this process. In this paper, we propose an optimized model for network function orchestration, function combination model(FCM). Our main contributions are as following. First, network functions are featured with a new abstraction, and are open to external providers. And FCM identifies network functions using unique type, and organizes their instances distributed over the network with the appropriate way. Second, with the specialized demands, we can combine function instances under the global network views, and formulate it into the problem of Boolean linear program(BLP). A simulated annealing algorithm is designed to approach optimal solution for this BLP. Finally, the numerical experiment demonstrates that our model can create outstanding composite schemas efficiently. | Hongchao Hu Lin Pang Zhenpeng Wang Guozhen Cheng | 2017 | China Communications2017，14，2： | 2 |
| 4 | Photo- luminescence and Raman studies in thin-film materi- als: Transition from amorphous to microcrystalline silicon显示文摘 | Yue Guozhen Lorentzen J D Lin Jing | 1999 | Appl Phys Lett1999，75，4： | 1 |
| 5 | Interfacial-Strain-Induced Structural and Polarization Evolutions in Epitaxial Multiferroic BiFeO_3(001) Thin Films显示文摘Varying the film thickness is a precise route to tune the interfacial strain to manipulate the properties of the multiferroic materials.Here,to explore the effects of the interfacial strain on the properties of the multiferroic BiFeO_3films,we investigated thickness-dependent structural and polarization evolutions of the BiFeO_3 films.The epitaxial growth with an atomic stacking sequence of BiO/TiO_2 at the interface was confirmed by scanning transmission electron microscopy.Combining X-ray diffraction experiments and first-principles calculations,a thickness-dependent structural evolution was observed from a fully strained tetragonality to a partially relaxed one without any structural phase transition or rotated twins.The tetragonality(c/a) of the BiFeO_3 films increases as the film thickness decreases,while the polarization is in contrast with this trend,and the size effect including the depolarization field plays a crucial role in this contradiction in thinner films.These findings offer an alternative strategy to manipulate structural and polarization properties by tuning the interfacial strain in epitaxial multiferroic thin films. | 郭海中 Ruiqiang Zhao Kui-juan Jin Lin Gu Dongdong Xiao Zhenzhong Yang Xiaolong Li Le Wang Xu He Junxing Gu Qian Wan Can Wang Huibin Lu Chen Ge Meng He Guozhen Yang | 2015 | 功能材料信息2015，12，3： | 1 |
| 6 | Photoluminescence and Raman Studies in Thin-film Materials:Transition from Amorphous to Microcrystalline Silicon显示文摘 | Guozhen Y Lorentzen D Jing Lin | 1999 | Applied Physics Letter1999，75，4： | 1 |
| 7 | Interactive Effects Between Temperature and PM_(2.5) on Mortality:A Study of Varying Coefficient Distributed Lag Model-Guangzhou,Guangdong Province,China,2013-2020显示文摘Introduction:There is a large body of epidemiological evidence showing significantly increased mortality risks from air pollution and temperature.However,findings on the modification of the association between air pollution and mortality by temperature are mixed.Methods:We used a varying coefficient distributed lag model to assess the complex interplay between air temperature and PM_(2.5) on daily mortality in Guangzhou City from 2013 to 2020,with the aim of establishing the PM_(2.5)-mortality association at different temperatures and exploring synergetic mortality risks from PM_(2.5) and temperature on vulnerable populations.Results:We observed near-linear concentrationresponse associations between PM_(2.5) and mortality across different temperature levels.Each 10μg/m^(3)increase of PM_(2.5) in low,medium,and high temperature strata was associated with increments of 0.73%[95%confidence interval(CI):0.38%,1.09%],0.12%(95%CI:−0.27%,0.52%),and 0.46%(95%CI:0.11%,0.81%)in non-accidental mortality,with a statistically significant difference between low and medium temperatures(P=0.02).There were significant modification effects of PM_(2.5) by low temperature for cardiovascular mortality and among individuals 75 years or older.Conclusions:Low temperatures may exacerbate physiological responses to short-term PM_(2.5) exposure in Guangzhou,China. | Sujuan Chen Hang Dong Mengmeng Li Lin Huang Guozhen Lin Qiyong Liu Boguang Wang Jun Yang | 2022 | China CDC weekly2022，4，26： | 1 |
| 8 | Discovery and characterization of gene cassettes-containing integrons in clinical strains of Riemerella anatipestifer显示文摘 | Fuying Zheng Guozhen Lin Jizhang Zhou Xiaoan Cao Xiaowei Gong Guanghua Wang Changqing Qiu | 2011 | Veterinary Microbiology (-)2011，，3： | 1 |
| 9 | Novel Electric Double‐Layer Capacitor with a Coaxial Fiber Structure显示文摘 | Xuli Chen Longbin Qiu Jing Ren Guozhen Guan Huijuan Lin Zhitao Zhang Peining Chen Yonggang Wang Huisheng Peng | 2013 | Adv Mater2013，，44： | 1 |
| 10 | Novel systemic lupus erythematosus autoantigens identified by human protein microarray technology显示文摘 | Wei Huang Chaojun Hu Haipan Zeng Ping Li Lei Guo Xiaofeng Zeng Guozhen Liu Fengchun Zhang Yongzhe Li Lin Wu | 2012 | Biochemical and Biophysical Research Communications2012，，2： | 1 |
| 11 | Clinical Observation on Shuanghuanglian Powder in Treating Viral Myocarditis of Children显示文摘 | LIN Guozhen LIU Dongmei ZHU Lin | 2000 | CJIM2000，6，2： | 1 |
| 12 | Photoluminescence and Raman studies in thin-film materials: Transition from amorphous to microcrystalline silicon显示文摘 | Guozhen Yue Lorentzen D Jing Lin | 1999 | Applied Physics Letters1999，75，4： | 1 |
| 13 | Protein microarray:A key approach of proteomics显示文摘Proteins are vital parts of living organisms,for they consist of the main components of physiological metabolic pathways.The expression and modification status of proteins in cells are time-and space-dependent based upon functions as well as responses to stress.A subject aiming at understanding of protein status under certain physiological condition in a large scale,termed proteomics,is fundamentally important in life science.Although the proteomic investigation mainly relies on electrophoresis,liquid chromatography,and mass spectrometry,protein microarray is emerging as one of new techniques,and its power is being recognized in the field recently.Herein,we highlight progress in protein microarray,both its generation and application. | Wei HUANG Lin WU Guozhen LIU Siqi LIU | 2010 | Frontiers in Biology2010，5，4： | 0 |
| 14 | Structural biology investigation of EMF effect on insulin in solution显示文摘It was reported that the a-helix of protein molecules could be destroyed when they were exposed to the electromagnetic field(EMF) and finally the signal transduction could be affected.To study this effect,one signal molecule,insulin,was exposed to electromagnetic fields at different combinations of the field strength,repetition rate and exposure time.For the first time,structural biology approach was used to detect the EMF effect.The results of a series of measurements on the interaction of electromagnetic fields with insulin in vitro are described.Under our experimental conditions,no effects of electromagnetic field exposure were observed on the molecular conformation. | LIU Yahui CHEN Yongbin XU Chunyan XU Shenglong SUN Bo ZHOU Huan SUN Lihua YU Feng TANG Lin GUO Guozhen HE Jianhua | 2011 | Nuclear Science and Techniques2011，22，3： | 0 |
| 15 | The quaternion beam model for hard-magnetic flexible cantilevers显示文摘The recently developed hard-magnetic soft(HMS)materials manufactured by embedding high-coercivity micro-particles into soft matrices have received considerable attention from researchers in diverse fields,e.g.,soft robotics,flexible electronics,and biomedicine.Theoretical investigations on large deformations of HMS structures are significant foundations of their applications.This work is devoted to developing a powerful theoretical tool for modeling and computing the complicated nonplanar deformations of flexible beams.A so-called quaternion beam model is proposed to break the singularity limitation of the existing geometrically exact(GE)beam model.The singularity-free governing equations for the three-dimensional(3D)large deformations of an HMS beam are first derived,and then solved with the Galerkin discretization method and the trustregion-dogleg iterative algorithm.The correctness of this new model and the utilized algorithms is verified by comparing the present results with the previous ones.The superiority of a quaternion beam model in calculating the complicated large deformations of a flexible beam is shown through several benchmark examples.It is found that the purpose of the HMS beam deformation is to eliminate the direction deviation between the residual magnetization and the applied magnetic field.The proposed new model and the revealed mechanism are supposed to be useful for guiding the engineering applications of flexible structures. | Wei CHEN Guozhen WANG Yiqun LI Lin WANG Zhouping YIN | 2023 | Applied Mathematics and Mechanics(English Edition)2023，44，5： | 0 |
| 16 | YBa_(2)Cu_(3)O_(7-x) Superconducting Thin Films Grown on CaNdA1O_(4)(100) Substrates显示文摘We report the fabrication of high temperature superconducting YBa_(2)Cu_(3)O_(7-x) thin films on CaNdA1O_(4)(100) substrate by pulsed laser deposition.Films have excellent features.X-ray diffraction patterns show that thin films are epitaxial with c-axis orientation normal to the surface of su bstrate.The four-terminal measurements indicate the zero resistance temperature of 92.1 K,and transition width of 0.7K,the critical current density of 3×10^(6)A/cm^(2)at 77K and under zero magnetic field. | XU Shifa ZHOU Yueliang LÜHuibin CUI Dafu CHEN Zhenghao YANG Guozhen TIAN Yongjun LIU Junzheng LI Lin CHANG Yingchuan HOU Desen FAN Hui ZHANG Zuren | 1994 | Chinese Physics Letters1994，11，5： | 0 |
| 17 | Bibliometric evaluation of the status of Picea research and research hotspots:comparison of China to other countries显示文摘Picea Mill.species are important components of boreal and subalpine forests.They have a wide geographical range in the Northern Hemisphere,extending from the Eurasian continent to North America.In this study,publications on Picea species from 2002 to 2016 were identified via the Web of Science(WoS)and the China National Knowledge Infrastructure(CNKI)databases,and subjected to relationship network visualization using CiteSpace software.This study represents the first such analysis of Picea and provides a reference for bibliometrics in forest tree species research.The results show that the total number of publications on Picea archived in WoS was20,958 and that the number of papers published annually has increased over time,peaking at 1725 in 2013.The studies were mainly conducted in North America,Europe and Asia;among them,Canada published the most papers and showed the strongest betweenness centrality(0.11).Among research institutions,the Swedish University of Agricultural Sciences in Uppsala had the highest publication record.The research contributions of the Chinese Academy of Sciences,the Chinese Academy of Forestry,and Beijing Forestry University have improved rapidly in recent years,greatly enhancing the international impact of Chinese research in this field.The research contents were grouped into five categories:forest ecosystems,pest resistance,extraction and functional analyses of active ingredients from various plant organs,nursery and afforestation techniques,and timber quality research.In China,the number of papers from the CNKI database was4532,increasing at an even pace.The research topics on Picea included forest ecosystems,seedling and afforestation techniques,basic studies on individual species and populations,and pests and diseases.Within and outside China,hotspots in Picea research included the relationships between Picea and environmental factors,and the genomic sequences of Picea. | Guozhen Duan Yu'e Bai Dongmei Ye Tao Lin Peng Peng Min Liu Shulan Bai | 2020 | Journal of Forestry Research2020，31，4： | 0 |
| 18 | N:ZnO/MoS_(2)-heterostructured flexible synaptic devices enabling optoelectronic co-modulation for robust artificial visual systems显示文摘With the merits of non-contact,highly efficient,and parallel computing,optoelectronic synaptic devices combining sensing and memory in a single unit are promising for constructing neuromorphic computing and artificial visual chip.Based on this,a N:ZnO/MoS_(2)-heterostructured flexible optoelectronic synaptic device is developed in this work,and its capability in mimicking the synaptic behaviors is systemically investigated under the electrical and light signals.Versatile synaptic functions,including synaptic plasticity,long-term/short-term memory,and learning-forgetting-relearning property,have been achieved in this synaptic device.Further,an artificial visual memory system integrating sense and memory is emulated with the device array,and the visual memory behavior can be regulated by varying the light parameters.Moreover,the optoelectronic co-modulation behavior is verified by applying mixed electric and light signals to the array.In detail,a transient recovery property is discovered when the electric signals are applied in synergy during the decay of the light response,of which property facilitates the development of robust artificial visual systems.Furthermore,by superimposing electrical signals during the light response process,a differentiated response of the array is achieved,which can be used as a proof of concept for the color perception of the artificial visual system. | Lei Xu Wenxiao Wang Yang Li Yonghui Lin Wenjing Yue Kai Qian Qinglei Guo Jeonghyun Kim Guozhen Shen | 2024 | Nano Research2024，17，3： | 0 |
| 19 | Preface to the Special Issue on Flexible Materials and Structures for Bioengineering,Sensing,and Energy Applications显示文摘Human body with curved and soft interfaces requests advanced flexible materials and structures for the interaction with organs and signal collection from targets in applications such as bioengineering and diagnostic devices.Among them,it is highly demanded to achieve creative design in flexible materials and structures with great stretchable capability for required applications.To this end,both inorganic and organic materials could be adopted and designed with assembly and self-assembly methods for flexible electronics and electrodes.Soft or flexible materials and structures inspired by nature can lead to highly conformal contacts between devices and the human body.These approaches hold great potential for applications in flexible electronics,medical imaging technology and portable disease diagnostics.Novel strategy on related sensors/actuator and energy storage/generation devices could overcome certain limitations on flexible materials engineering and thus advance the field as well.All these methods would deliver a profound impact to our future intelligent society. | Yongfeng Mei Wei Gao Hui Fang Yuan Lin Guozhen Shen | 2020 | Journal of Semiconductors2020，41，4： | 0 |
| 20 | High-performance terahertz modulators induced by substrate field in Te-based all-2D heterojunctions显示文摘High-performance active terahertz modulators as the indispensable core components are of great importance for the next generation communication technology.However,they currently suffer from the tradeoff between modulation depth and speed.Here,we introduce two-dimensional(2D)tellurium(Te)nanofilms with the unique structure as a new class of optically controlled terahertz modulators and demonstrate their integrated heterojunctions can successfully improve the device performances to the optimal and applicable levels among the existing all-2D broadband modulators.Further photoresponse measurements confirm the significant impact of the stacking order.We first clarify the direction of the substrate-induced electric field through first-principles calculations and uncover the unusual interaction mechanism in the photoexcited carrier dynamics associated with the charge transfer and interlayer exciton recombination.This advances the fundamental and applicative research of Te nanomaterials in high-performance terahertz optoelectronics. | Pujing Zhang Qihang Liang Qingli Zhou Jinyu Chen Menglei Li Yuwang Deng Wanlin Liang Liangliang Zhang Qinghua Zhang Lin Gu Chen Ge Kui-juan Jin Cunlin Zhang Guozhen Yang | 2024 | Light(Science & Applications)2024，13，3： | 0 |
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