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| 1 | Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: Results of a multicent显示文摘AIM: Anti-Saccharomyces cerevisiae antibodies (ASCA), anti-nuclear associated anti-neutrophil antibodies (NANA) and antibodies to exocrine pancreas (PAB), are serological tools for discriminating Crohn’s disease (CrD) and ulcerative colitis (UC). Like CrD, coeliac disease (CoD) is an inflammatory bowel disease (IBD) associated with (auto) antibodies. Performing a multicenter study we primarily aimed to determine the performance of ASCA, NANA and PAB tests for IBD diagnosis in children and adults, and secondarily to evaluate the prevalence of these markers in CoD. METHODS: Sera of 109 patients with CrD, 78 with UC, 45 with CoD and 50 healthy blood donors were retrospectively included. ASCA, NANA and PAB were detected by indirect immunofluorescence (IIF). RESULTS: ASCA+/NANA- profile displayed a positive predictive value of 94.2% for CrD. Detection of ASCA was correlated with a more severe clinical profile of CrD and treatment of the disease did not influence their serum levels. ASCA positivity was found in 37.9% of active CoD.PAB were found in 36.7% CrD and 13.3% CoD patients and were not correlated with clinical features of CrD, except with an early onset of the disease. Fifteen CrD patients were ASCA negative and PAB positive. CONCLUSION: ASCA and PAB detected by IIF are specific markers for CrD although their presence does not rule out a possible active CoD. The combination of ASCA, NANA and PAB tests improves the sensitivity of immunological markers for CrD. Repeating ASCA, NANA, and PAB testing during the course of CrD has no clinical value. | S Desplat-Jégo C Johanet A Escande J Goetz N Fabien N Olsson E Ballot J Sarles JJ Baudon JC Grimaud M Veyrac P Chamouard RL Humbel | 2007 | World Journal of Gastroenterology2007，13，16： | 24 |
| 2 | Structural and morphologic evaluation of a novel detergent-enzymatic tissue-engineered tracheal tubular matrix显示文摘 | Jungebluth P Tetsuhiko Go M Asnaghi A | | 0，，： | 1 |
| 3 | Scasonal patterns of nitriogen and denitrification in a natural and a restored salt marsh 显示文摘 | Paerl H W Go M C | 1995 | Estuaries1995，18，： | 1 |
| 4 | Evidence for the electrolysis'of water by atmospheric-pressure plasmas formed at the surface of aqueous solutions显示文摘 | Witzke M Rumbach P Go D B | 2012 | Journal of Physics D: Applied Physics2012，45，44： | 1 |
| 5 | Extraction of gelatin from fish skins by high pressure treatment显示文摘 | M C Go'mez-Guille'n B Gime'nez P Montero | 2005 | Food hydrocolloids2005，19，： | 1 |
| 6 | Seasonal patterns of nitrification and denitrification in a natural and a restored salt marsh显示文摘 | Thompson S P Paeri H W Go M C | 1995 | Estuaries1995，18，2： | 1 |
| 7 | Microbial transglutaminase as a tool to restore the functionality of gluten from insect - damaged wheat 显示文摘 | Bonet A Caballero P A Go'mez M | 2005 | Cereal Chemistry2005，82，4： | 1 |
| 8 | Antimalarial alkoxylated and hydroxylated chalcones:Structure-activity relationship analysis显示文摘 | Liu M Wilairat P Go M L | 2001 | J Med Chem2001，44，： | 1 |
| 9 | Antiplasmodial chalcones inhibit sorbitol-induced hemolysis of Plasmodium falciparum-infected erythrocytes显示文摘 | Go M L Liu M Wilairat P | | 0，，09： | 1 |
| 10 | Antimalarial alkoxylated and hydroxylated chalones:structure-activity relationship analysis显示文摘 | LIU M WILAIRAT P GO ML | 2001 | J Med Chem2001，44，25： | 1 |
| 11 | Open mesh versus non-mesh for repair of femoral and inguinal hernia显示文摘 | Mc Cormack K Graham P Go P M | 2002 | Cochrane Database Syst Rev2002，13，00： | 1 |
| 12 | Role of CYP2D6 in the stereoselective disposition of venlafaxine in humans显示文摘 | Eap CB Lessard E Baumann P Brawand-Amey M Yessine MA Hara GO | 2003 | Pharmacogenetics2003，13，： | 1 |
| 13 | Plasma membrane cholesterol is a key molecule in shear stress-dependent activation of extracellular signal-regulated kinase显示文摘 | Park H Go Y M St John P L | 1998 | J Biol Chem1998，273，32： | 1 |
| 14 | At,Evalu- ation of elemental sulphur in bioclesulphurized low rank coals显示文摘 | Go nsalvesh L Marinov S P Stefanova M | 2011 | Fuel2011，90，： | 1 |
| 15 | Effect of rosuvastatin on low-density lipoprotein cholesterol in patients with hypercholesterolemia显示文摘 | Anders GO John P John M | 2001 | Am J Cardiol2001，88，： | 1 |
| 16 | Adesign concept with a displacement dependent semi-active hydraulic damper for energy dissipation 显示文摘 | Shih M H Sung W P Go C G | 2003 | Experimental Techniques2003，27，6： | 1 |
| 17 | Clinical transplantation of a tissue-engineered airway显示文摘 | Paolo Macchiarini Philipp Jungebluth Tetsuhiko Go M Adelaide Asnaghi Louisa E Rees Tristan A Cogan Amanda Dodson Jaume Martorell Silvia Bellini Pier Paolo Parnigotto Sally C Dickinson Anthony P Hollander Sara Mantero Maria Teresa Conconi Martin A Birchall | 2008 | The Lancet2008，，9655： | 1 |
| 18 | E-heritage in the globalizing society: enabling cross-cuhural engagement through ICT显示文摘 | GO F M LEE R M RUSSO A P | 2003 | Information Technology & Tourism2003，6，1： | 1 |
| 19 | Third-generation cholecystectomy by natural orifices:transgastric and transvesical combined approach (with video)显示文摘 | Rolanda C Lima E Pêgo J M | 2007 | Gastrointest Endosc2007，65，1： | 1 |
| 20 | A Design Concept with a Displacement Dependent Semi-active Hydraulic Damper for Energy Dissipation显示文摘 | Shih M H Sung W P Go C G | 2003 | Experimental Techniques2003，27，6： | 1 |
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