|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: Results of a multicent显示文摘AIM: Anti-Saccharomyces cerevisiae antibodies (ASCA), anti-nuclear associated anti-neutrophil antibodies (NANA) and antibodies to exocrine pancreas (PAB), are serological tools for discriminating Crohn’s disease (CrD) and ulcerative colitis (UC). Like CrD, coeliac disease (CoD) is an inflammatory bowel disease (IBD) associated with (auto) antibodies. Performing a multicenter study we primarily aimed to determine the performance of ASCA, NANA and PAB tests for IBD diagnosis in children and adults, and secondarily to evaluate the prevalence of these markers in CoD. METHODS: Sera of 109 patients with CrD, 78 with UC, 45 with CoD and 50 healthy blood donors were retrospectively included. ASCA, NANA and PAB were detected by indirect immunofluorescence (IIF). RESULTS: ASCA+/NANA- profile displayed a positive predictive value of 94.2% for CrD. Detection of ASCA was correlated with a more severe clinical profile of CrD and treatment of the disease did not influence their serum levels. ASCA positivity was found in 37.9% of active CoD.PAB were found in 36.7% CrD and 13.3% CoD patients and were not correlated with clinical features of CrD, except with an early onset of the disease. Fifteen CrD patients were ASCA negative and PAB positive. CONCLUSION: ASCA and PAB detected by IIF are specific markers for CrD although their presence does not rule out a possible active CoD. The combination of ASCA, NANA and PAB tests improves the sensitivity of immunological markers for CrD. Repeating ASCA, NANA, and PAB testing during the course of CrD has no clinical value. | S Desplat-Jégo C Johanet A Escande J Goetz N Fabien N Olsson E Ballot J Sarles JJ Baudon JC Grimaud M Veyrac P Chamouard RL Humbel | 2007 | World Journal of Gastroenterology2007，13，16： | 24 |
| 2 | 慢性肾脏病中的炎症和动脉硬化:慢性肾功能不全队列研究中的发现显示文摘慢性肾脏病(chronic kidney disease,CKD)和动脉硬化程度与心血管病发病率和死亡率增加相关。目前认为炎症在动脉硬化发展中发挥作用,而CKD被认为是一种促炎症反应的状态。CKD患者的动脉僵硬度增加,横断面数据提示CKD中增多的炎症标志物与较高动脉僵硬度值相关。 | Peyster E Chen J Feldman HI Go AS Gupta J Mitra N Pan Q Porter A Rahman M Raj D Reilly M Wing MR Yang W Townsend RR 陈云 叶鹏 | 2017 | 中华高血压杂志2017，25，11： | 12 |
| 3 | Search for a dark photon in the π 0 → e + e ? γ decay显示文摘 | P. Adlarson W. Augustyniak W. Bardan M. Bashkanov F.S. Bergmann M. Ber?owski H. Bhatt A. Bondar M. Büscher H. Calén I. Ciepa? H. Clement D. Coderre E. Czerwiński K. Demmich E. Doroshkevich R. Engels W. Erven W. Eyrich P. Fedorets K. F?hl K. Fransson F. Go | 2013 | Physics Letters B . 2013 (1-3)2013，，1： | 3 |
| 4 | A regulatory feedback loop involving p63 and IRF6 links the pa'thogenesis of 2 genetically different human ectodermal dysplasias显示文摘 | Moretti F Marinari g go Iacono N | 2010 | J Clin Invest2010，120，5： | 1 |
| 5 | Impact of proteinuria and glo- merular filtration rate on risk of thromboembolism in atrial fibrilla- tion: the anticoagulation and risk factors in atrial fibrillation ( ATRIA ) study 显示文摘 | Go AS Fang MC Udaltsova N | 2009 | Circulation2009，119，10： | 1 |
| 6 | Ultrahigh porosity in Metal-organic frameworks显示文摘 | Furukawa H Ko N Go Y B | 2010 | Science2010，329，： | 1 |
| 7 | C ollective variable description of native protein d yn am ics显示文摘 | Hayward S Go N | 1995 | A nnual R eview of P h y sica l Chem istry1995，46，1： | 1 |
| 8 | Impact of proteinuria and glomerular filtration rate on risk of thromboembolism in atrial fibrilla- tion the anticoagulation and risk factors in atrial fibrillation (AT- RIA) study显示文摘 | Go AS Fang MC Udaltsova N | 2009 | Circulation2009，119，10： | 1 |
| 9 | Nonmotor mani- festations in Parkinson disease显示文摘 | Bernal-Pacheco O Limotai N Go CL | 2012 | Neurologist2012，18，1： | 1 |
| 10 | Antioxidant capacity of the Spanish mediterranean diet显示文摘 | Saura-Calixto F Go(n)i I | 2006 | Food Chemistry2006，，94： | 1 |
| 11 | Interaction of IgA with Fca receptors of human mesangial cells activates transcription factor nuclear factor-kB and induces expression and synthesis of monocyte chemoattractant protein-1, IL-8, and IFN-inducible protein 10 显示文摘 | Duque N Go' mez-Guerro C Egido J | 1997 | J Immunol1997，159，7： | 1 |
| 12 | A molecular marker-based linkage map of diploid bananas (Musa acuminata)显示文摘 | S. Fauré J. L. Noyer J. P. Horry F. Bakry C. Lanaud D. Gońzalez de León | 1993 | Theoretical and Applied Genetics1993，，4： | 1 |
| 13 | Association of MDR1 (C3435T) polymorphism and resistance to carbamazepine in epileptic patients from Turkey 显示文摘 | Ozgon GO Bebek N Gul G | 2008 | European Neurology2008，59，12： | 1 |
| 14 | Maintenance strategy based on a multicriterion classification of equipments 显示文摘 | E'LIX C Go'mez de Leo'n Hijes JOSE Javier Ruiz Cartagena | 2006 | Reliability Engineering and System Safety2006，91，： | 1 |
| 15 | Prognostic value of NT- proBNP and an adapted monin score in patients with asymptomatic aortic stenosis显示文摘 | Farre N Go mez M Molina L | 2014 | Rev Esp Cardiol(Engl Ed)2014，67，1： | 1 |
| 16 | Factors associated with local recurrence and cause - specific survival in patients with ductal carcinoma in situ of the breast treated with breast - conserving therapy or mastectomy显示文摘 | Vargas C Kestin L Go N | 2005 | Int J Radiat Oncol Biol Phys2005，63，5： | 1 |
| 17 | Differentiation of liver epithelial (stem-like) cells into hepatoeytes induced by eoeuhure with hepatic stellate ceils 显示文摘 | Hirokazu N Kunihiko T Go W | 2002 | Biochem Biophys Res Commun2002，293，5： | 1 |
| 18 | Telomerase antagonists GRN163 and GRNI63L inhibit tumor growth and in-crease chemosensitivity of human hepatoma 显示文摘 | DJOJOSUBROTO MW CHIN AC GO N | 2005 | Hepatology2005，42，5： | 1 |
| 19 | Extraction of gelatin from fish skins by high pressure treatment显示文摘 | M C Go'mez-Guille'n B Gime'nez P Montero | 2005 | Food hydrocolloids2005，19，： | 1 |
| 20 | Effect of grape antioxidant dietary fiber on the lipid oxidation of raw and cooked chicken hamburgers显示文摘 | Sáyago-Ayerdi S G Brenes A Go(n)i I | 2009 | LWT-Food Science and Technology2009，，42： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员