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| 1 | 皮质下小血管病诊断的共识声明显示文摘血管性认知损害是用于描述一组涉及大血管和小血管的散发性和遗传性异质性疾病的诊断术语。皮质下小血管病可导致腔隙性梗死和进行性白质损害。被称为宾斯旺格病(Binswanger's disease, BD)的进行性白质损害患者构成了从单纯血管性疾病到合并神经变性病变的疾病谱。BD患者是一个相对同质性的亚组,存在缺氧缺血、腔隙性梗死和炎症,它们协同作用破坏血脑屏障和髓鞘。通过临床、脑脊液、神经心理学和影像学检查获得的多模式疾病标记物能促进该亚组患者的鉴别。本共识声明确定了一系列基于基础病理学改变的潜在生物学标记物,这将有助于诊断以及将来协作性治疗试验的患者选择。 | Gary A Rosenberg Anders Wallin Joanna M Wardlaw Hugh S Markus Joan Montaner Leslie Wolfson Costantino Iadecola Berislav V Zlokovic Anne Joutel Martin Dichgans Marco Duering Reinhold Schmidt Amos D Korczyn Lea T Grinberg Helena C Chui Vladimir Hachinski 王训师 张劼 陈涵丰 俞娅美 徐子奇 罗本燕 | 2016 | 国际脑血管病杂志2016，24，6： | 18 |
| 2 | Anticoagulant modulation of inflammation in severe sepsis显示文摘Inflammation and coagulation are so tightly linked that the cytokine storm which accompanies the development of sepsis initiates thrombin activation and the development of an intravascular coagulopathy. This review examines the interaction between the inflammatory and coagulation cascades, as well as the role of endogenous anticoagulants in regulating this interaction and dampening the activity of both pathways. Clinical trials attempting to improve outcomes in patients with severe sepsis by inhibiting thrombin generation with heparin and or endogenous anticoagulants are reviewed. In general, these trials have failed to demonstrate that anticoagulant therapy is associated with improvement in mortality or morbidity. While it is possible that selective patients who are severelyill with a high expected mortality may be shown to benefit from such therapy, at the present time none of these anticoagulants are neither approved nor can they be recommended for the treatment of sepsis. | Karen S Allen Eva Sawheny Gary T Kinasewitz | 2015 | World Journal of Critical Care Medicine2015，4，2： | 14 |
| 3 | Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial显示文摘 | Matthew T Seymour Sarah R Brown Gary Middleton Timothy Maughan Susan Richman Stephen Gwyther Catherine Lowe Jennifer F Seligmann Jonathan Wadsley Nick Maisey Ian Chau Mark Hill Lesley Dawson Stephen Falk Ann O’Callaghan Kim Benstead Philip Chambers Alfred | 2013 | Lancet Oncology2013，，8： | 6 |
| 4 | Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial显示文摘 | William T Cefalu Lawrence A Leiter Kun-Ho Yoon Pablo Arias Leo Niskanen John Xie Dainius A Balis William Canovatchel Gary Meininger | 2013 | The Lancet2013，，： | 3 |
| 5 | Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial显示文摘 | Matthew T Seymour Lindsay C Thompson Harpreet S Wasan Gary Middleton Alison E Brewster Stephen F Shepherd M Sinead O’Mahony Timothy S Maughan Mahesh Parmar Ruth E Langley | 2011 | The Lancet2011，，9779： | 2 |
| 6 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 7 | Redicting Business Failure: A Macroeconomic Perspective 显示文摘 | Rose Peter S Andrews Wesley T Giroux Gary A P | 1982 | Journal of Accounting Auditing and Finance1982，，1： | 1 |
| 8 | Strands of theory and research in collective behavior显示文摘 | Gary T Marx James L Wood | 1975 | Annual Review of Sociology1975，1，： | 1 |
| 9 | Depressive symptoms and metabolic control in African 一 Americans with type 2 diabetes 显示文摘 | Gary T L Crum R M Cooper-Patrick L | 2000 | Diabetes Care2000，23，1： | 1 |
| 10 | Paleoshoreline evidence for postglacial tilting in Southern Manitoba显示文摘 | Gary E T Donald R C Bruce G B | 1998 | Journal of Paleolin- nology1998，19，： | 1 |
| 11 | Recommendations for the management of COPD显示文摘 | Gary T | 2006 | Chest2006，，： | 1 |
| 12 | Thrombosis of the inferior vena cava related to Ormond's disease 显示文摘 | Paetzold S Gary T Hafner F | 2013 | Clin Rheumatol2013，，： | 1 |
| 13 | Sommargren laser doppler velocimeter for velocity and length measurements of moving surfaces 显示文摘 | BRUCE E T FRANK C D GARY E | 1984 | Applied Optics January1984，23，1： | 1 |
| 14 | Inactivation of viruses and bacteria by ozone, with and without sonication显示文摘 | GARY R BURLESON T M MURRAY MORRIS POLLARD | 1975 | Applied microbiology march1975，29，3： | 1 |
| 15 | Developments in recirculating systems for Arctic char culture in North America显示文摘 | SUMMERFELT STEVEN T GARY WILTON DAVID ROBERTS | | 0，，： | 1 |
| 16 | Clinical and demographic factors associated with fractures among older Americans 显示文摘 | Taylor AJ Gary LC Arora T | 2011 | Osteoporos lnt2011，22，4： | 1 |
| 17 | Milev Interactions of sodium montmorillonite with poly(acrylic acid) 显示文摘 | NGUYEN H T GARY R DENNIS A | 2005 | Journal of Colloid and Interface Science2005，290，2： | 1 |
| 18 | Infrared filters using metallic photonic band gap structures on flexible substrates 显示文摘 | Sandhya G P Gary T T | 1997 | Applied Physics Letters1997，71，17： | 1 |
| 19 | Measuring the Nursing , Teaching , and Interpersonal Eflectiveness of clinical Instruetors 显示文摘 | Gary T McCauley | 1993 | journal of Nursing Education1993，32，7： | 1 |
| 20 | Screening for primary aldosteronism in essential hypertension : diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity显示文摘 | Gary L Schwartz T Stephen T | 2005 | Clinical Chemistry2005，51，2： | 1 |
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