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| 1 | Metastatic type 1 gastric carcinoid:A real threat or just a myth?显示文摘AIM:To describe disease characteristics and treatment modalities in a group of rare patients with metastatic gastric carcinoid type 1(GCA1).METHODS:Information on clinical,biochemical,radiological,histopathological findings,the extent of the disease,as well as the use of different therapeutic modalities and the long-term outcome were recorded.Patients’data were assessed at presentation,and thereafter at 6 to 12 monthly intervals both clinically and biochemically,but also endoscopically and histopathologically.Patients were evaluated for the presence of specific symptoms;the presence of autoimmune disorders and the presence of other gastrointestinal malignancies in other family members were also recorded.The evaluation of response to treatment was defined using established WHO criteria.RESULTS:We studied twenty consecutive patients with a mean age of 55.1 years.The mean follow-up period was 83 mo.Twelve patients had regional lymph node metastases and 8 patients had liver metastases.The primary tumor mean diameter was 20.13±10.83mm(mean±SD).The mean Ki-67 index was 6.8%±11.2%.All but one patient underwent endoscopic or surgical excision of the tumor.The disease was stable in all but 3 patients who had progressive liver disease.All patients remained alive during the follow-up period.CONCLUSION:Metastatic GCA1 carries a good overall prognosis,being related to a tumor size of≥1 cm,an elevated Ki-67 index and high serum gastrin levels. | Simona Grozinsky-Glasberg Dimitrios Thomas Jonathan R Strosberg Ulrich-Frank Pape Stephan Felder Apostolos V Tsolakis Krystallenia I Alexandraki Merav Fraenkel Leonard Saiegh Petachia Reissman Gregory Kaltsas David J Gross | 2013 | World Journal of Gastroenterology2013，19，46： | 11 |
| 2 | A review of human carcinogens—Part B: biological agents显示文摘 | Véronique Bouvard Robert Baan Kurt Straif Yann Grosse Béatrice Secretan Fatiha El Ghissassi Lamia Benbrahim-Tallaa Neela Guha Crystal Freeman Laurent Galichet Vincent Cogliano | 2009 | Lancet Oncology2009，，4： | 4 |
| 3 | Carcinogenicity of alcoholic beverages显示文摘 | Robert Baan Kurt Straif Yann Grosse Béatrice Secretan Fatiha El Ghissassi Véronique Bouvard Andrea Altieri Vincent Cogliano | 2007 | Lancet Oncology2007，，4： | 2 |
| 4 | Tentorial dural arteriovenous fistula presenting as myelopathy: Case series and review of literature显示文摘Dural arteriovenous fistula(DAVF) is a rare type of cerebral arteriovenous malformation. Common presenting symptoms are related to hemorrhage. However, rarely these patients may present with myelopathy. We present two cases of DAVF presenting as rapidly progressive myelopathy. Two treatment options are available: microsurgical interruption of the fistula and endovascular embolization. These treatment options of DAVFs have improved significantly in the last decade. The optimal treatment of DAVFs remains controversial, and there is an ongoing debate as to whether primary endovascular or primary microsurgical treatment is the optimal management for these lesions. However, despite treatment a high percentage of patients are still left with severe disability. The potential for functional ambulation in patients with DAVF is related to the time of intervention. This emphasizes the important of early diagnosis and early intervention in DAVF. The eventual outcome may depend on several factors, such as the duration of symptoms, the degree of disability before treatment, and the success of the initial procedure to close the fistula. The usage of magnetic resonance imaging and selective angiography has significantly improved the ability to characterize DAVFs, however, these lesions remain inefficiently diagnosed. If intervention is delayed even prolonged time in rehabilitation does not change the grave prognosis. This review outlines the presentation, classication and management of DAVF as well as discussing patient outcomes. | Robert Gross Rushna Ali Max Kole Curtis Dorbeistein Mahesh V Jayaraman Muhib Khan | 2014 | World Journal of Clinical Cases2014，2，12： | 2 |
| 5 | The dopamine D3 recep-tor plays an essential role in alcohol-seeking and relapse显示文摘 | Vengeliene V Leonardi-Essmann F Perreau-Lenz S Gebicke-Haerter P Drescher K Gross G | 2006 | FASEB J2006，20，13： | 1 |
| 6 | Inhibition of pressure natriuresis in mice lacking the AT2 receptor显示文摘 | Gross V Schunck WH Honeck H | 2000 | Kidney Int2000，57，19： | 1 |
| 7 | Chemotactic signaling via carbohydrate phosphotransferase systems in Escherichia coli显示文摘 | Neumann S Grosse K Sourjik V | | 0，，： | 1 |
| 8 | 查看详情显示文摘 | D W Yoon D E Gross V M Lynch J M Sessler B P Hay C H Lee | | 0，，： | 1 |
| 9 | Zur morphologie der Bromeliaceen samen unter berucksichtig-ung systematisch-taxonomischer aspekte显示文摘 | Gross E Bromelienstudien I V | 1988 | Tropische und subtropische Pflanzenwelt1988，64，： | 1 |
| 10 | Membrane signaling and progesterone in female and male osteoblasts:involvement of intracellalar Ca2+,inositol triphosphate and diacylglycerol,but not cAMP显示文摘 | Grosse B Kachkache M Le Mellay V | 2000 | J Cell Biochem2000，79，2： | 1 |
| 11 | Infammatory mediators and cytokines-new aspects of the pathophysiology and assessment of severity of acute pancreatitis显示文摘 | Gross V Leser HG Heinisch A | | 0，，06： | 1 |
| 12 | Sedimentary characteristics and origin of the Late Pleistocene Ice Complex on north-east Siberian Arctic coastal lowlands and islands - A review 显示文摘 | Schin'meister L Kunitsky V Grosse G | 2011 | Quaternary International2011，241，： | 1 |
| 13 | A Lumping and Reaction Scheme for Catalytic Cracking 显示文摘 | SOLOMON M J GROSS B STERLING E V | 1976 | AIChE J1976，22，4： | 1 |
| 14 | Copper metalorganic chemical vapor deposition reactions of hexafluoroacetylacetonate Cu(I) vinyltrimethylsilane and bis (hexafluoroacetylacetonate) Cu(II) adsorbed on titanium nitride 显示文摘 | DONNELLY V M GROSS M E | 1993 | Journal of Vacuum Science Technology A1993，，： | 1 |
| 15 | Inflammatory me- diators and cytokines-new aspects of the pathophysiology and assessment of severity of acute pancreatitis显示文摘 | Gross V Leser HG Heiniseh A | 1993 | Hepa- togastroenterology1993，40，6： | 1 |
| 16 | Cardiac hypertrophy and fibrosis in chro- nic L-NAME-treated AT2 receptor-deficient mice 显示文摘 | Gross V Obst M Kiss E | 2004 | J Hypertens2004，22，5： | 1 |
| 17 | Extended serogrouping scheme for motile, mesophilic Aeromonas spp 显示文摘 | THOMAS L V GROSS R J | 1990 | Clinical Microbiol1990，28，3： | 1 |
| 18 | Chronic effects of lovastatin and bezafibrate on cortical andmedullary hemodynamics in deoxycorticosterone acetate salt hypertensive mice显示文摘 | GROSS V SCHNEIDER W SCHUNCK WH | 1999 | J Am Soc Nephrol1999，10，7： | 1 |
| 19 | Species Independence of Mutual Information in Coding and Non-coding DNA显示文摘 | GROSSE I HERZEL H BULDYREV V | 2000 | Physical Review2000，61，： | 1 |
| 20 | Pharmacokinetics of caffeine in plasma and saliva, and the influence of caffeine abstinence on CYP1A2 metrics显示文摘 | Perera V Gross AS Xu H McLachlan AJ | 2011 | J Pharm Pharmacol2011，63，9： | 1 |
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