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| 1 | Gastric cancer: Current status of lymph node dissection显示文摘D2 procedure has been accepted in Far East as the standard treatment for both early(EGC) and advanced gastric cancer(AGC) for many decades. Recently EGC has been successfully treated with endoscopy by endoscopic mucosal resection or endoscopic submucosal dissection, when restricted or extended Gotoda's criteria can be applied and D1+ surgery is offered only to patients not fitted for less invasive treatment. Furthermore, two randomised controlled trials(RCTs) have been demonstrating the non inferiority of minimally invasive technique as compared to standard open surgery for the treatment of early cases and recently the feasibility of adequate D1+ dissection has been demonstrated also for the robot assisted technique. In case of AGC the debate on the extent of nodal dissection has been open for many decades. While D2 gastrectomy was performed as the standard procedure in eastern countries, mostly based on observational and retrospective studies, in the west the Medical Research Council(MRC), Dutch and Italian RCTs have been conducted to show a survival benefit of D2 over D1 with evidence based medicine. Unfortunately both the MRC and the Dutch trials failed to show a survival benefit after the D2 procedure, mostly due to the significant increase of postoperative morbidity and mortality, which was referred to splenopancreatectomy. Only 15 years after the conclusion of its accrual, the Dutch trial could report a significant decrease of recur-rence after D2 procedure. Recently the long term survival analysis of the Italian RCT could demonstrate a benefit for patients with positive nodes treated with D2 gastrectomy without splenopancreatectomy. As nowadays also in western countries D2 procedure can be done safely with pancreas preserving technique and without preventive splenectomy, it has been suggested in several national guidelines as the recommended procedure for patients with AGC. | Maurizio Degiuli Giovanni De Manzoni Alberto Di Leo Domenico D'Ugo Erica Galasso Daniele Marrelli Roberto Petrioli Karol Polom Franco Roviello Francesco Santullo Mario Morino | 2016 | World Journal of Gastroenterology2016，22，10： | 29 |
| 2 | A Likert Scale-Based Model for Benchmarking Operational Capacity,Organizational Resilience,and Disaster Risk Reduction显示文摘Likert scales are a common methodological tool for data collection used in quantitative or mixed-method approaches in multiple domains.They are often employed in surveys or questionnaires,for benchmarking answers in the fields of disaster risk reduction,business continuity management,and organizational resilience.However,both scholars and practitioners may lack a simple scale of reference to assure consistency across disciplinary fields.This article introduces a simple-to-use rating tool that can be used for benchmarking responses in questionnaires,for example,for assessing disaster risk reduction,gaps in operational capacity,and organizational resilience.We aim,in particular,to support applications in contexts in which the target groups,due to cultural,social,or political reasons,may be unsuitable for in-depth analyses that use,for example,scales from 1 to 7 or from 1 to 10.This methodology is derived from the needs emerged in our recent fieldwork on interdisciplinary projects and from dialogue with the stakeholders involved.The output is a replicable scale from 0 to 3 presented in a table that includes category labels with qualitative attributes and descriptive equivalents to be used in the formulation of model answers.These include examples of levels of resilience,capacity,and gaps.They are connected to other tools that could be used for in-depth analysis.The advantage of our Likert scale-based response model is that it can be applied in a wide variety of disciplines,from social science to engineering. | Gianluca Pescaroli Omar Velazquez Irasema Alcántara-Ayala Carmine Galasso Patty Kostkova David Alexander | 2020 | International Journal of Disaster Risk Science2020，11，3： | 8 |
| 3 | 一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas. | Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P | 2014 | 中华神经外科疾病研究杂志2014，13，5： | 6 |
| 4 | Current status of device-assisted enteroscopy: Technical matters, indication, limits and complications显示文摘Enteroscopy, defined as direct visualization of the smallbowel with the use of a fiberoptic or capsule endoscopy, has progressed considerably over the past severalyears. The need for endoscopic access to improvediagnosis and treatment of small bowel disease hasled to the development of novel technologies one ofwhich is noninvasive, the video capsule, and a type of invasive technique, the deviceassisted enteroscopy.In particular, the device-assisted enteroscopy consiststhen of three different types of instruments all able toallow, in skilled hands, to display partially or throug-hout its extension (if necessary) the small intestine.Newer devices, double balloon, single balloon and spiral endoscopy, are just entering clinical use. The aim of this article is to review recent advances in small bowelenteroscopy, focusing on indications, modifications toimprove imaging and techniques, pitfalls, and clinical applications of the new instruments. With new technologies, the trials and tribulations of learning new endo-scopic skills and determining their role in the diagnosisand treatment of small bowel disease come. Identification of small bowel lesions has dramatically improved.Studies are underway to determine the best strategy toapply new enteroscopy technologies for the diagnosisand management of small bowel disease, particularly obscure bleeding. Vascular malformations such as angiectasis and small bowel neoplasms as adenocar cinomaor gas trointestinal stromal tumors. Complete entero-scopy of the small bowel is now possible. However, because of the length of the small bowel, endoscopic examination and the rapeutic maneuvers require significant skill, radiological assistance, the use of deep sedation with the assistance of the anesthetist. Prospective ran-domized studies are needed to guide diagnostic testing and the rapy with these new endoscopic techniques. | Riccioni Maria Elena Urgesi Riccardo Cianci Rossella Alessandra Bizzotto Galasso Domenico Costamagna Guido | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，10： | 5 |
| 5 | Antiplatelet therapy in very elderly and comorbid patients with acute coronary syndromes显示文摘With population ageing and rise of life expectancy,a progressively increasing proportion of patients presenting with an acute coronary syndrome(ACS)are older adults,including those at extreme chronological age.Increasing amounts of data,including randomized clinical trials,have shown that the benefits of an early revascularization are maintained also at very old age,resulting in improved outcome after an acute coronary event.On the contrary,the optimal antiplatelet therapy(APT)remains unclear in these patients,because of both safety and efficacy concerns.Indeed,age-related multiple organ dysfunction and high prevalence of comorbidities may on the one hand reduce the therapeutic effects of administered drugs;on the other hand,it leads to increased vulnerability to drug toxicity and side effects.Therefore,management of APT is particularly challenging in elderly patients because of higher risk of both ischemic and bleeding events.The aim of the present paper is to review the current evidence,gaps in knowledge and ongoing research regarding APT in the setting of an ACS in elderly and very elderly patients,and in those with significant comorbidities including chronic kidney disease,diabetes mellitus and frailty. | Roberta De Rosa Federico Piscione Gennaro Galasso Stefano De Servi Stefano Savonitto | 2019 | Journal of Geriatric Cardiology2019，16，2： | 4 |
| 6 | Minimum platelet count threshold before invasive procedures in cirrhosis:Evolution of the guidelines显示文摘Cirrhotic patients with severe thrombocytopenia are at increased risk of bleeding during invasive procedures.The need for preprocedural prophylaxis aimed at reducing the risk of bleeding in cirrhotic patients with thrombocytopenia who undergo scheduled procedures is assessed via the platelet count;however,establishing a minimum threshold considered safe is challenging.A platelet count≥50000/μL is a frequent target,but levels vary by provider,procedure,and specific patient.Over the years,this value has changed several times according to the different guidelines proposed in the literature.According to the latest guidelines,many procedures can be performed at any level of platelet count,which should not necessarily be checked before the procedure.In this review,we aim to investigate and describe how the guidelines have evolved in recent years in the evaluation of the minimum platelet count threshold required to perform different invasive procedures,according to their bleeding risk. | Marco Biolato Federica Vitale Tiziano Galasso Antonio Gasbarrini Antonio Grieco | 2023 | World Journal of Gastrointestinal Surgery2023，15，2： | 2 |
| 7 | Pancreatic duct replication is increased with obesity and type2 diabetes in humans显示文摘 | Butler AE Galasso R Matveyenko A | 2010 | Diabetoiogia2010，53，1： | 1 |
| 8 | Detailed compositional comparison of acidic NSO compounds in biodegraded reservoir and surface crude oils by negative ion electrospray Fourier transform ion cyclotron resonance mass spectrometry显示文摘 | HUGHEY C A GALASSO S A ZUMBERGL J E | 2007 | Fuel2007，86，56： | 1 |
| 9 | Late reopening of an occluded infarct related artery improves left ventricular function and long term clinical outcome显示文摘 | Piscione F Galasso G De Luca G | 2005 | Heart2005，91，5： | 1 |
| 10 | Current research on influenza and other respiratory viruses:Ⅱ international symposium显示文摘 | Munoz FM Galasso GJ Gwaltney JM Jr | 2000 | Antiviral Res2000，46，2： | 1 |
| 11 | Monocyte chemoattractant piotein-1 is a mediator of acute excitotoxic injury in neonatal rat brain显示文摘 | Galasso JM Liu Y Szaflarski J | 2000 | Neuroscience2000，101，3： | 1 |
| 12 | Adiponectin promotes endothelial progenitor cell number and function显示文摘 | Rei Shibata Carsten Skurk Noriyuki Ouchi Gennaro Galasso Kazuhisa Kondo Taiki Ohashi Masayuki Shimano Shinji Kihara Toyoaki Murohara Kenneth Walsh | 2008 | FEBS Letters2008，，11： | 1 |
| 13 | CEO overconfidence and innovation 显示文摘 | GALASSO A SIMCOE T S | 2010 | NBER Working Paper2010，，： | 1 |
| 14 | Current research on influenza and other respiratory virus : II international symposium 显示文摘 | Munoz FM Galasso GJ Gwaltney JM | 2000 | Antiviral Res2000，46，2： | 1 |
| 15 | Single-flowered vetch (Vicia articulata Hornem.): A relic crop in Italy显示文摘 | G. Laghetti A.R. Piergiovanni I. Galasso K. Hammer P. Perrino | 2000 | Genetic Resources and Crop Evolution2000，，4： | 1 |
| 16 | Uncertainty in early warning predictions of engineering ground motion parame- ters: What really matters? 显示文摘 | Iervolino I M Giorgio C Galasso | 2009 | Geophysical Research Let-ters2009，36，： | 1 |
| 17 | Comparison of Molecular Cytogenetic and Genetic Analyses in Accessions of the Two Biotypes of Vicia benghalensis L.显示文摘 | INCORONATA GALASSO GABRIELLA SONNANTE DONATO GUIDO TOTA DOMENICO PIGNONE | 1997 | Annals of Botany1997，，3： | 1 |
| 18 | CEO Overconfidence and innovation显示文摘 | GALASSO A SIMCOE T S | 2011 | Management Science2011，57，8： | 1 |
| 19 | The anti -inflammatory cytokine IL - 1Ra protects from high fat diet - induced hyperglycemia显示文摘 | Sauter NS Schuhhess vr Galasso R | 2008 | Endocrinology2008，149，5： | 1 |
| 20 | MicroRNA expression signaturesin solid malignancies显示文摘 | Galasso M Sandhu SK Volinia S | 2012 | Cancer J2012，18，3： | 1 |
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