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| 1 | Hepatitis B in pregnancy显示文摘Chronic hepatitis B virus (HBV) infection affects about 350 million individuals worldwide. Management of HBV infection in pregnancy is difficult because of several peculiar and somewhat controversial aspects. The aim of the present review is to provide a tool that may help physicians to correctly manage HBV infection in pregnancy. This review focuses on (1) the effect of pregnancy on HBV infection and of HBV infection on pregnancy; (2) the potential viral transmission from mother to newborn despite at-birth prophylaxis with immunoglobulin and vaccine; (3) possible prevention of mother-to-child transmission through antiviral drugs, the type of antiviral drug to use considering their efficacy and potential teratogenic effect, and the timing of their administration and discontinuation; and (4) the evidence for the use of elective caesarean section vs vaginal delivery and the possibility of breastfeeding. | Guglielmo Borgia Maria Aurora Carleo Giovanni Battista Gaeta Ivan Gentile | 2012 | World Journal of Gastroenterology2012，18，34： | 16 |
| 2 | Application of a Robust Model Reference Adaptive Control Algorithm to a Nonlinear Automotive Actuator显示文摘Model reference adaptive control is a viable control method to impose the demanded dynamics on plants whose parameters are affected by large uncertainty. In this paper, we show by means of experiments that robust adaptive methods can effectively face nonlinearities that are common to many automotive electromechanical devices. We consider here, as a representative case study, the control of a strongly nonlinear automotive actuator. The experimental results confirm the effectiveness of the method to cope with unmodeled nonlinear terms and unknown parameters. In addition, the engineering performance indexes computed on experimental data clearly show that the robust adaptive strategy provides better performance compared with those given by a classical model-based control solution with fixed gains. | Alessandro di Gaeta Umberto Montanaro | 2014 | International Journal of Automation and computing2014，11，4： | 5 |
| 3 | Statements from the Taormina expert meeting on occult hepatitis B virus infection显示文摘 | Giovanni Raimondo Jean-Pierre Allain Maurizia R. Brunetto Marie-Annick Buendia Ding-Shinn Chen Massimo Colombo Antonio Craxì Francesco Donato Carlo Ferrari Giovanni B. Gaeta Wolfram H. Gerlich Massimo Levrero Stephen Locarnini Thomas Michalak Mario U. Mon | 2008 | Journal of Hepatology2008，，4： | 5 |
| 4 | Sustained virological response: A milestone in the treatment of chronic hepatitis C显示文摘AIM: To evaluate the long-term eradication of hepatitis C virus (HCV) infection and liver-related complications in chronically infected patients that have achieved sustained virological response. METHODS: One hundred and fifty subjects with chronic hepatitis C (CHC) or cirrhosis and sustained virological response (SVR) between the years of 1989 and 2008 were enrolled in a long-term clinical follow-up study at the Gastrointestinal and Liver Unit of the University Hospital of Naples 'Federico Ⅱ'. At the beginning of the study, the diagnosis of HCV infection was made on the basis of serum positivity for antibodies to HCV and detection of HCV RNA transcripts, while a diagnosis of chronic hepatitis was formulated using imaging techniques and/or a liver biopsy. SVR was achieved by interferon-based therapy, both conventional and pegylated, with and without ribavirin treatment. The patients were evaluated for follow-up at a median length of 8.6 years, but ranged from 2-19.9 years. Among them, 137 patients had pre-treatment CHC and 13 had cirrhosis. The patients were followed with clinical, biochemical, virological, and ultrasound assessments on a given schedule. Finally, a group of 27 patients underwent a liver biopsy at the beginning of the study and transient elastography at their final visit to evaluate changes in liver fibrosis. RESULTS: The median follow-up was 8.6 years (range 2-19.9 years). HCV RNA remained undetectable in all patients, even in patients who eventually developed liver-related complications, indicating no risk of HCV recurrence. Three liver-related complications were observed: two cases of hepatocellular carcinoma and one case of bleeding from esophageal varices resulting in an incidence rate of 0.23%/person per year. Further, all three complications took place in patients diagnosed with cirrhosis before treatment began. Only one death due to liver-related causes occurred, resulting in a mortality rate of 0.077% person per year. This amounts to a 99.33% survival rate in our cohort of patients after therapy for HCV infection. Finally, of the 27 patients who underwent a liver biopsy at the beginning of the study, a reduction in liver fibrosis was observed in 70.3% of the cases; only three cases registering values of liver stiffness indicative of significant fibrosis. CONCLUSION: Patients with CHC and SVR show an excellent prognosis with no risk of recurrence and a very low rate of mortality. Our data indicate that viruseradication following interferon treatment can last up to 20 years. | Filomena Morisco Rocco Granata Tommaso Stroffolini Maria Guarino Laura Donnarumma Laura Gaeta Ilaria Loperto Ivan Gentile Francesco Auriemma Nicola Caporaso | 2013 | World Journal of Gastroenterology2013，19，18： | 4 |
| 5 | Restored Function of HBV-Specific T Cells After Long-term Effective Therapy With Nucleos(t)ide Analogues显示文摘 | Carolina Boni Diletta Laccabue Pietro Lampertico Tiziana Giuberti Mauro Viganò Simona Schivazappa Arianna Alfieri Marco Pesci Giovanni B. Gaeta Giuseppina Brancaccio Massimo Colombo Gabriele Missale Carlo Ferrari | 2012 | Gastroenterology2012，，4： | 3 |
| 6 | Almond diversity and homozygosity define structure, kinship, inbreeding, and linkage disequilibrium in cultivated germplasm, and reveal genomic associations with nut and seed weight显示文摘Almond[Prunus dulcis Miller(D.A.Webb)]is the main tree nut species worldwide.Here,genotyping-by-sequencing(GBS)was applied to 149 almond cultivars from the ex situ collections of the Italian Council for Agricultural Research(CREA)and the Spanish National Research Council(CSIC),leading to the detection of 93,119 single-nucleotide polymorphisms(SNPs).The study of population structure outlined four distinct genetic groups and highlighted diversification between the Mediterranean and Californian gene pools.Data on SNP diversity and runs of homozygosity(ROHs)allowed the definition of kinship,inbreeding,and linkage disequilibrium(LD)decay in almond cultivated germplasm.Four-year phenotypic observations,gathered on 98 cultivars of the CREA collection,were used to perform a genome-wide association study(GWAS)and,for the first time in a crop species,homozygosity mapping(HM),resulting in the identification of genomic associations with nut,shell,and seed weight.Both GWAS and HM suggested that loci controlling nut and seed weight are mostly independent.Overall,this study provides insights on the almond cultivation history and delivers information of major interest for almond genetics and breeding.In a broader perspective,our results encourage the use of ROHs in crop science to estimate inbreeding,choose parental combinations minimizing the risk of inbreeding depression,and identify genomic footprints of selection for specific traits. | Stefano Pavan Chiara Delvento Rosa Mazzeo Francesca Ricciardi Pasquale Losciale Liliana Gaeta Nunzio D’Agostino Francesca Taranto Raquel Sanchez-Perez Luigi Ricciardi Concetta Lotti | 2021 | Horticulture Research2021，8，1： | 2 |
| 7 | Fever of unknown origin:a systematic review of the literature for 1995-2004 显示文摘 | GAETA G B FUSCO F M NARDIELLO S | 2006 | Nucl Med Commun2006，27，3： | 1 |
| 8 | Metals ions and neurodegeneration显示文摘 | Molina-holgado F Hider RC Gaeta A | 2007 | Biometals2007，20，34： | 1 |
| 9 | Twisted Ovarian Fibroma with High Signal Intensity on T1- weighted MR Image:a New Sign of Torsion of Ovarian Tumors显示文摘 | Minutoli F Blandino A Gaeta M | 2001 | Eur Radiol2001，11，7： | 1 |
| 10 | Pattern of recurrence of bronchioloaveolar cell carcinoma after surgical resection:a radiological,histologic,and immunohistochemical study显示文摘 | Gaeta M Blandino A Pergolizzi S | | 0，，03： | 1 |
| 11 | CT and MR imaging findings in athletes with early tibial stress injuries:comparison with bone scintigraphy findings and emphasis on cortical abnormalities显示文摘 | Gaeta M Minutoli F Scribano E | | 0，，02： | 1 |
| 12 | Fever of unknown origin:a systematic review of the literature for 1995-2004显示文摘 | Gaeta GB Fusco FM Nardiello S | 2006 | Nucl Med Commun2006，27，3： | 1 |
| 13 | Osteopathic manipulative treatment in the emergency department for patients with acute ankle sprains 显示文摘 | Eisenhart AW Gaeta TJ Yens DP | 2003 | J Am Osteopath Assoc2003，103，9： | 1 |
| 14 | Shock index in the first trimesterof pregnancy and its relationship to ruptured eetopic pregnancy显示文摘 | Birkhahn RH Gaeta TJ Bei R | 2002 | Acad Emerg Med2002，9，2： | 1 |
| 15 | ELAM-1 mediates cell adhesion by recognition of a carbhydrate ligand, Sialyl-Lex 显示文摘 | Phillips M L Nudel man E Gaeta F C | 1990 | Science1990，250，4984： | 1 |
| 16 | Long-lasting phosphorescence in oxygen-deficient Ge-doped silica glasses at room temperature显示文摘 | Qiu J Gaeta A L Hirao K | 2001 | Chem Phys Lett2001，，333： | 1 |
| 17 | Pattern of recurrence of Bronchioloarcell carcinoma after surgrcal resection : a radiological, histolagic, and innunohis tochemical study 显示文摘 | Gaeta M Blandino A Pergolizzi S | 2003 | Lung cancer2003，62，： | 1 |
| 18 | The radiology of the pterygoid canal:normal and pathologic finding显示文摘 | Gaeta M Blandino A | 1987 | Am J Neuroradioly1987，8，3： | 1 |
| 19 | Metals ions and neurodegeneration显示文摘 | Molina-Holgado F Hider RC Gaeta A | 2007 | Biometals2007，20，34： | 1 |
| 20 | Computed Tomography Halo Sign in Pulmonary Nodules:Frequency and Diagnostic Value显示文摘 | Gaeta M Blandino A Scribano E | 1999 | J Thorac Imaging1999，14，2： | 1 |
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