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| 1 | Early phase of acute pancreatitis: Assessment and management显示文摘Acute pancreatitis(AP) is a potentially life-threatening disease with a wide spectrum of severity. The overall mortality of AP is approximately 5%. According to the revised Atlanta classification system, AP can be classified as mild, moderate, or severe. Severe AP often takes a clinical course with two phases, an early and a late phase, which should both be considered separately. In this review article, we first discuss general aspects of AP, including incidence, pathophysiology, etiology, and grading of severity, then focus on the assessment of patients with suspected AP, including diagnosis and risk stratification, followed by the management of AP during the early phase, with special emphasis on fluid therapy, pain management, nutrition, and antibiotic prophylaxis. | Veit Phillip Jrg M Steiner Hana Algül | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，3： | 19 |
| 2 | Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting. | Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov | 2014 | World Journal of Gastroenterology2014，20，45： | 9 |
| 3 | Hypothalamic-pituitary-adrenal axis function during perinatal depression显示文摘Abnormal function of the hypothalamic–pituitary–adrenal(HPA) axis is an important pathological finding in pregnant women exhibiting major depressive disorder. They show high levels of cortisol proinflammatory cytokines, hypothalamic-pituitary peptide hormones and catecholamines, along with low dehydroepiandrosterone levels in plasma. During pregnancy, the TH2 balance together with the immune system and placental factors play crucial roles in the development of the fetal allograft to full term. These factors, when altered, may generate a persistent dysfunction of the HPA axis that may lead to an overt transfer of cortisol and toxicity to the fetus at the expense of reduced activity of placental 11β-hydroxysteroid dehydrogenase type 2. Epigenetic modifications also may contribute to the dysregulation of the HPA axis. Affective disorders in pregnant women should be taken seriously, and therapies focused on preventing the deleterious effects of stressors should be implemented to promote the welfare of both mother and baby. | Phillipe Leff Gelman Mónica Flores-Ramos Margarita López-Martínez Carlos Cruz Fuentes Juan Pablo Reyes Grajeda | 2015 | Neuroscience Bulletin2015，31，3： | 6 |
| 4 | 酗酒对年轻人血压水平和其他心血管健康指标的影响:2011-2014年美国国家健康与营养调查结果显示文摘无节制地饮酒(酗酒)在年轻人中流行率最高,然而,酗酒对年龄18~45岁的个体血压和其他心血管健康指标的影响知之甚少。为了确定长期酗酒对血压、血脂和血糖水平的影响,并确定这些关联在男性和女性之间是否存在差异,Piano等分析了来自美国国家健康与营养调查(the US national health and nutrition examination survey)的数据. | 刘莉 叶鹏 Piano MR Burke L Kang M Phillips SA | 2018 | 中华高血压杂志2018，26，8： | 5 |
| 5 | Dairy food consumption and body weight and fatness studied longitudinally over the adolescent period显示文摘 | PHILLIPS S M BANDINI L G CYR H | 2003 | International Journal of Obesity2003，27，： | 2 |
| 6 | A new aluminum hydroxide octamer (SO4)5 · 16H2O显示文摘 | Casey W H Olmstead M M Phillips B L | 2005 | Inorg Chem2005，44，： | 1 |
| 7 | Dissemination and evaluation of the ASAS/EULAR eeommendations for the management of ankylosing spondylitis: results of a study among 1507 rheumatologists 显示文摘 | GOSSEC L DOUGADOS M PHILLIPS C | 2008 | Ann Rheum Dis2008，67，6： | 1 |
| 8 | Guaranteed passive balancing transformations for model order reduction 显示文摘 | Phillips J R Daniel L Silveira L M | 2003 | IEEE Transactions on Computer aided Design of Integrated Circuits and Systems2003，22，8： | 1 |
| 9 | Natural levels of dimethyl sulfide in rough rice and its products显示文摘 | Ren Y L Desmarchelier J M Phillip W | 2001 | Journal of Agricultural and Food Chemistry2001，49，： | 1 |
| 10 | Determination of organic acids in Vaccinium berry standard reference materials显示文摘 | Phillips M M Case R J Rimmer C A Sander L C Sharpless K E Wise S A Yen J H | 2010 | Analytical and Bioanalytical Chemistry2010，398，1： | 1 |
| 11 | Storage of Light in Atomic Vapor显示文摘 | Phillips D F Fleischhauer A Mair A Walsworth R L Lukin M D | 2001 | Phys Rev Lett2001，86，78： | 1 |
| 12 | Advancing fine root research with minirhizotrons显示文摘 | Johnson M G Tingey D T Phillips D L | 2001 | Environmental and Experimental Botany2001，45，3： | 1 |
| 13 | Reproduction in the deepwater squid Moroteuthis ingens 显示文摘 | Jackson G D Semmens J M Phillips K L | 2004 | Mar Biol2004，145，： | 1 |
| 14 | Condensed phase relations in the systems ZrO2-WO2-WO3 and HfO2-WO2-WO3显示文摘 | SCROGER M G PHILLIPS B | 1967 | Journal of The America Ceramic Society1967，50，： | 1 |
| 15 | Genetic instability of plant tissue cultures,breakdown of normal controls显示文摘 | Phillips R L Kaeppler S M Olhoft P | 1994 | Proc Natl Acad Sci USA1994，91，： | 1 |
| 16 | Dolomitization front geometry,fluid flow patterns and the origin of massive dolomite 显示文摘 | Wilson E N Hardie L A Phillips O M | 1990 | America Journal of Science1990，290，5： | 1 |
| 17 | The use of eonfocal microscopy for the examination of El2 sheet plastinated human tissue显示文摘 | Phillips M Nash L Barnett R | 2002 | J Int Sue Plastination2002，17，1： | 1 |
| 18 | Validation of ventilation rate measurement methods and ammonia emission from naturally ventilated dairy and beef buildings in the United Kingdom显示文摘 | Demmers T G M Phillips VR Short L S | 2001 | Journal of Agricultural Engineering Research2001，，： | 1 |
| 19 | Lapse, relapse and survival among opiate addicts after treatment : a prospective follow - up study显示文摘 | Gossop M Green L Phillips G | 1989 | Br J Psychiatry1989，154，： | 1 |
| 20 | Direct measurement of optical phase in the near field 显示文摘 | Knight J C Pottage J M Kakarantzas G Russell P St J | 2000 | Applied Physics Letters2000，76，5： | 1 |
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